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                             125 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 ABCA1 and cholesterol transfer protein Aster-A promote an asymmetric cholesterol distribution in the plasma membrane Ogasawara, Fumihiko

298 12 p.
artikel
2 A bovine antibody possessing an ultralong complementarity-determining region CDRH3 targets a highly conserved epitope in sarbecovirus spike proteins Burke, Matthew J.

298 12 p.
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3 A CACNA1C variant associated with cardiac arrhythmias provides mechanistic insights in the calmodulation of L-type Ca2+ channels Zhao, Juan

298 12 p.
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4 Accessing isotopically labeled proteins containing genetically encoded phosphoserine for NMR with optimized expression conditions Vesely, Cat Hoang

298 12 p.
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5 A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators Ciulla, Daniel A.

298 12 p.
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6 A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling Brüggenthies, Johanna B.

298 12 p.
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7 A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines Mideksa, Yonatan G.

298 12 p.
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8 A higher plant FAD synthetase is fused to an inactivated FAD pyrophosphatase Lynch, Joseph H.

298 12 p.
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9 A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions Guan, Wendy

298 12 p.
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10 A method for the isolation and characterization of autophagic bodies from yeast provides a key tool to investigate cargos of autophagy Kawamata, Tomoko

298 12 p.
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11 A mutated glycosaminoglycan-binding domain functions as a novel probe to selectively target heparin-like epitopes on tumor cells Xu, Yingying

298 12 p.
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12 Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1 Busch, Lukas

298 12 p.
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13 Analysis of Plasmodium falciparum myosin B ATPase activity and structure in complex with the calmodulin-like domain of its light chain MLC-B Pires, Isa

298 12 p.
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14 Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice Harada, Naoki

298 12 p.
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15 A new nanobody-enzyme fusion protein–linked immunoassay for detecting antibodies against influenza A virus in different species Ji, Pinpin

298 12 p.
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16 Angiotensin-converting enzyme 2 improves hepatic insulin resistance by regulating GABAergic signaling in the liver Chen, Qi

298 12 p.
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17 Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants Watt, Kathryn J.C.

298 12 p.
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18 A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes Scarpitti, MaKenzie R.

298 12 p.
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19 A novel connection between Trypanosoma brucei mitochondrial proteins TbTim17 and TbTRAP1 is discovered using Biotinylation Identification (BioID) Soto-Gonzalez, Fidel

298 12 p.
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20 A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding Shillingford, Shanelle

298 12 p.
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21 Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1 Chen, Yiyan

298 12 p.
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22 A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers Pirhaghi, Mitra

298 12 p.
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23 Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules Haanen III, Terrance J.

298 12 p.
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24 Biophysical insights into glucose-dependent transcriptional regulation by PDX1 Usher, Emery T.

298 12 p.
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25 Brain-derived neurotrophic factor stimulates the retrograde pathway for axonal autophagy Sidibe, David Kader

298 12 p.
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26 Cancer-associated Notch receptor variants lead to O-fucosylation defects that deregulate Notch signaling Pennarubia, Florian

298 12 p.
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27 Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing Huang, Fan

298 12 p.
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28 Chimeric galectin-3 and collagens: Biomarkers and potential therapeutic targets in fibroproliferative diseases Nangia-Makker, Pratima

298 12 p.
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29 Control of cell surface expression of GABAA receptors by a conserved region at the end of the N-terminal extracellular domain of receptor subunits Yuan, Banghao

298 12 p.
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30 Correction: Aurora A–mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression Jiang, Ya

298 12 p.
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31 Correction: Cytochrome c nitrite reductase from the bacterium Geobacter lovleyi represents a new NrfA subclass Campeciño, Julius

298 12 p.
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32 Correction: The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics Francis, Vincent

298 12 p.
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33 Cover
298 12 p.
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34 Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α2β2 tetramer Murthy, Abhinandan V.

298 12 p.
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35 Crystal structures of photosystem II from a cyanobacterium expressing psbA 2 in comparison to psbA 3 reveal differences in the D1 subunit Nakajima, Yoshiki

298 12 p.
artikel
36 Cytochrome b5 reductases: Redox regulators of cell homeostasis Hall, Robert

298 12 p.
artikel
37 Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition Haynes, Laura M.

298 12 p.
artikel
38 Dietary polyphenols link extracellular histones and nonhistone proteins Liu, Jiuyang

298 12 p.
artikel
39 Differential contributions of the proteasome, autophagy, and chaperones to the clearance of arsenite-induced protein aggregates in yeast Hua, Sansan

298 12 p.
artikel
40 Dimers of D76N-β2-microglobulin display potent antiamyloid aggregation activity Maya-Martinez, Roberto

298 12 p.
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41 Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment Donahue, Kristine

298 12 p.
artikel
42 Disentangling autoproteolytic cleavage from tethered agonist–dependent activation of the adhesion receptor ADGRL3 Perry-Hauser, Nicole A.

298 12 p.
artikel
43 Disruption of the glucagon receptor increases glucagon expression beyond α-cell hyperplasia in zebrafish Kang, Qi

298 12 p.
artikel
44 Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy Guhathakurta, Piyali

298 12 p.
artikel
45 Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise Komori, Tadasuke

298 12 p.
artikel
46 Export of polybasic motif–containing secretory proteins BMP8A and SFRP1 from the endoplasmic reticulum is regulated by surfeit locus protein 4 Tang, Xiao

298 12 p.
artikel
47 Flow cytometric reporter assays provide robust functional analysis of signaling complexes Muusse, Timothy W.

298 12 p.
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48 Gambogic acid and juglone inhibit RNase P through distinct mechanisms Wu Meyers, Nancy

298 12 p.
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49 Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors Moore, Amy

298 12 p.
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50 Glucagon changes substrate preference in gluconeogenesis Xu, Huiting

298 12 p.
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51 Glucagon-like peptide-1 analog liraglutide leads to multiple metabolic alterations in diet-induced obese mice Park, Seokjae

298 12 p.
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52 Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity Jin, Xiaohan

298 12 p.
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53 G protein gamma subunit, a hidden master regulator of GPCR signaling Kankanamge, Dinesh

298 12 p.
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54 Grim-19 plays a key role in mitochondrial steroidogenic acute regulatory protein stability and ligand-binding properties in Leydig cells Qu, Hu

298 12 p.
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55 Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP Chrispell, Jared D.

298 12 p.
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56 Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel CaV1.2 Bartels, Peter

298 12 p.
artikel
57 Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation Espinoza, Mateo F.

298 12 p.
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58 Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress Pitts, Stephanie

298 12 p.
artikel
59 Identification of a S-(2-succino)cysteine breakdown pathway that uses a novel S-(2-succino) lyase Hillmann, Katie B.

298 12 p.
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60 Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain Moecking, Jonas

298 12 p.
artikel
61 Intracellular pathogen Leishmania intervenes in iron loading into ferritin by cleaving chaperones in host macrophages as an iron acquisition strategy Sen, Sandhya

298 12 p.
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62 Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction Magat, Jenna

298 12 p.
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63 Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD Ostendorp, Anna

298 12 p.
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64 In vitro transdifferentiated signatures of goat preadipocytes into mammary epithelial cells revealed by DNA methylation and transcriptome profiling Yan, Xiao-Ru

298 12 p.
artikel
65 Long noncoding RNA HOTAIR regulates the stemness of breast cancer cells via activation of the NF-κB signaling pathway Wang, Jiajia

298 12 p.
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66 Long noncoding RNA SNHG5 promotes podocyte injury via the microRNA-26a-5p/TRPC6 pathway in diabetic nephropathy Zhou, Yan

298 12 p.
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67 Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin Kihn, Kyle

298 12 p.
artikel
68 Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells Aoyama, Megumi

298 12 p.
artikel
69 Loss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells Slade, Logan

298 12 p.
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70 Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV) Ishikawa, Yoshihiro

298 12 p.
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71 Macromolecular crowding amplifies allosteric regulation of T-cell protein tyrosine phosphatase Tun, May Thwe

298 12 p.
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72 Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis Prasad, Archna

298 12 p.
artikel
73 Mechanistic insights into poly(C)-binding protein hnRNP K resolving i-motif DNA secondary structures Wu, Wen-Qiang

298 12 p.
artikel
74 Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension Jacob, Christina

298 12 p.
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75 Metal migration and subunit swapping in ALS-linked SOD1: Zn2+ transfer between mutant and wild-type occurs faster than the rate of heterodimerization Dashnaw, Chad M.

298 12 p.
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76 Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity Wang, Zixuan

298 12 p.
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77 Might nontransferrin-bound iron in blood plasma and sera be a nonproteinaceous high-molecular-mass FeIII aggregate? Vali, Shaik Waseem

298 12 p.
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78 MITF is a novel transcriptional regulator of the calcium sensor STIM1: Significance in physiological melanogenesis Tanwar, Jyoti

298 12 p.
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79 Molecular simulation of lignin-related aromatic compound permeation through gram-negative bacterial outer membranes Vermaas, Josh V.

298 12 p.
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80 Mutations in the α4-α5 allosteric lobe of RAS do not significantly impair RAS signaling or self-association Whaby, Michael

298 12 p.
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81 N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains Stavenhagen, Kathrin

298 12 p.
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82 N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis Xie, Furong

298 12 p.
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83 OCA7 is a melanosome membrane protein that defines pigmentation by regulating early stages of melanosome biogenesis Beyers, Wyatt C.

298 12 p.
artikel
84 On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w Van Oss, S. Branden

298 12 p.
artikel
85 Ornate, large, extremophilic (OLE) RNA forms a kink turn necessary for OapC protein recognition and RNA function Lyon, Seth E.

298 12 p.
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86 Phosphatidylserine exposure modulates adhesion GPCR BAI1 (ADGRB1) signaling activity Lala, Trisha

298 12 p.
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87 PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis Gnanapradeepan, Keerthana

298 12 p.
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88 Products of the visual cycle are detected in mice lacking retinol binding protein 4, the only known vitamin A carrier in plasma Montenegro, Diego

298 12 p.
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89 Programmed death ligand 1 intracellular interactions with STAT3 and focal adhesion protein Paxillin facilitate lymphatic endothelial cell remodeling Schafer, Johnathon B.

298 12 p.
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90 Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells Kropotov, Andrey

298 12 p.
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91 Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1 Wang, Carl J.H.

298 12 p.
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92 Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing Huffines, Abigail K.

298 12 p.
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93 Redox properties and PAS domain structure of the Escherichia coli energy sensor Aer indicate a multistate sensing mechanism Maschmann, Zachary A.

298 12 p.
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94 Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet Selen, Ebru S.

298 12 p.
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95 Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding Alhumaidi, Maryam

298 12 p.
artikel
96 Role of the membrane anchor in the regulation of Lck activity Porciello, Nicla

298 12 p.
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97 Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury van Gijsel-Bonnello, Manuel

298 12 p.
artikel
98 Scaffold proteins as dynamic integrators of biological processes DiRusso, Christopher J.

298 12 p.
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99 Sequential hydrolysis of FAD by ecto-5′ nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B2 into cells Shichinohe, Natsuki

298 12 p.
artikel
100 Specificity of a β-porphyranase produced by the carrageenophyte red alga Chondrus crispus and implications of this unexpected activity on red algal biology Manat, Guillaume

298 12 p.
artikel
101 Spirodalesol analog 8A inhibits NLRP3 inflammasome activation and attenuates inflammatory disease by directly targeting adaptor protein ASC Liu, Wen

298 12 p.
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102 Src-mediated phosphorylation of the ribosome biogenesis factor hYVH1 affects its localization, promoting partitioning to the 60S ribosomal subunit DaDalt, Ashley A.

298 12 p.
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103 Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling Sunilkumar, Siddharth

298 12 p.
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104 Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission Egner, John M.

298 12 p.
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105 Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif Ru, Wenwen

298 12 p.
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106 Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction Chen, Xingchen

298 12 p.
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107 Suppression of amyloid-β fibril growth by drug-engineered polymorph transformation Mafimoghaddam, Sima

298 12 p.
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108 Targeting dendritic cells with TLR-2 ligand–coated nanoparticles loaded with Mycobacterium tuberculosis epitope induce antituberculosis immunity Kumar Das, Deepjyoti

298 12 p.
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109 TFEB acetylation promotes lysosome biogenesis and ameliorates Alzheimer’s disease–relevant phenotypes in mice Li, Tianyou

298 12 p.
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110 The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection Tsai, MuChun

298 12 p.
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111 The ferredoxin/thioredoxin pathway constitutes an indispensable redox-signaling cascade for light-dependent reduction of chloroplast stromal proteins Yoshida, Keisuke

298 12 p.
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112 The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy Sun, Shan

298 12 p.
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113 The interdependent transport of yeast vacuole Ca2+ and H+ and the role of phosphatidylinositol 3,5-bisphosphate Zhang, Chi

298 12 p.
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114 The leucine-rich repeat (LRR) domain of NLRP3 is required for NLRP3 inflammasome activation in macrophages Duan, Yanhui

298 12 p.
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115 The noncatalytic regions of the tyrosine kinase Tnk1 are important for activity and substrate specificity Ahmed, Sultan

298 12 p.
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116 The SCF–FBXW7 E3 ubiquitin ligase triggers degradation of histone 3 lysine 4 methyltransferase complex component WDR5 to prevent mitotic slippage Hänle-Kreidler, Simon

298 12 p.
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117 The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity Tomida, Seita

298 12 p.
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118 Three-dimensional structure of a mycobacterial oligoribonuclease reveals a unique C-terminal tail that stabilizes the homodimer Badhwar, Pooja

298 12 p.
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119 Toll-like receptor 4 and lipopolysaccharide from commensal microbes regulate Tembusu virus infection Wu, Zhen

298 12 p.
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120 Transmembrane anterior posterior transformation 1 regulates BMP signaling and modulates the protein stability of SMAD1/5 Wang, Bo

298 12 p.
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121 Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation Zhang, Yikai

298 12 p.
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122 Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10 Sheehan, Colin T.

298 12 p.
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123 Ultrahigh resolution MS1/MS2-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action Fan, Teresa W.-M.

298 12 p.
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124 Unusual reactivity of a flavin in a bifurcating electron-transferring flavoprotein leads to flavin modification and a charge-transfer complex Mohamed-Raseek, Nishya

298 12 p.
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125 Withdrawal: Toxoplasma gondii virulence factor ROP18 inhibits the host NF-κB pathway by promoting p65 degradation Du, Jian

298 12 p.
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                             125 gevonden resultaten
 
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