nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A dedicated C-6 β-hydroxyacyltransferase required for biosynthesis of the glycolipid anchor for Vi antigen capsule in typhoidal Salmonella
|
Liston, S.D. |
|
|
298 |
11 |
p. |
artikel |
2 |
Aging-associated REGγ proteasome decline predisposes to tauopathy
|
Tu, Jialu |
|
|
298 |
11 |
p. |
artikel |
3 |
Ancestral archaea expanded the genetic code with pyrrolysine
|
Guo, Li-Tao |
|
|
298 |
11 |
p. |
artikel |
4 |
Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death
|
Shrestha, Shikshya |
|
|
298 |
11 |
p. |
artikel |
5 |
Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage
|
Gao, Zhengyu |
|
|
298 |
11 |
p. |
artikel |
6 |
A programmable system to methylate and demethylate N 6-methyladenosine (m6A) on specific RNA transcripts in mammalian cells
|
Chang, Chen |
|
|
298 |
11 |
p. |
artikel |
7 |
Artificial pore blocker acts specifically on voltage-gated potassium channel isoform KV1.6
|
Gigolaev, Andrei M. |
|
|
298 |
11 |
p. |
artikel |
8 |
Aurora A–mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression
|
Jiang, Ya |
|
|
298 |
11 |
p. |
artikel |
9 |
Bacterial conversion of a host weapon into a nutritional signal
|
Valvano, Miguel A. |
|
|
298 |
11 |
p. |
artikel |
10 |
Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists
|
Irwin, Sean |
|
|
298 |
11 |
p. |
artikel |
11 |
BTK kinase activity is dispensable for the survival of diffuse large B-cell lymphoma
|
Yuan, Hongwei |
|
|
298 |
11 |
p. |
artikel |
12 |
Cell adhesion molecule CD44v10 promotes stem-like properties in triple-negative breast cancer cells via glucose transporter GLUT1-mediated glycolysis
|
Guo, Qian |
|
|
298 |
11 |
p. |
artikel |
13 |
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation
|
Wang, Hongrui |
|
|
298 |
11 |
p. |
artikel |
14 |
Computational and functional studies of the PI(4,5)P2 binding site of the TRPM3 ion channel reveal interactions with other regulators
|
Zhao, Siyuan |
|
|
298 |
11 |
p. |
artikel |
15 |
Cooperative assembly of filopodia by the formin FMNL2 and I-BAR domain protein IRTKS
|
Fox, Sarah |
|
|
298 |
11 |
p. |
artikel |
16 |
Coprinopsis cinerea dioxygenase is an oxygenase forming 10(S)-hydroperoxide of linoleic acid, essential for mushroom alcohol, 1-octen-3-ol, synthesis
|
Teshima, Takuya |
|
|
298 |
11 |
p. |
artikel |
17 |
Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion
|
Sparks, Robert P. |
|
|
298 |
11 |
p. |
artikel |
18 |
Correction: CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA
|
Su, Guangsong |
|
|
298 |
11 |
p. |
artikel |
19 |
Correction: Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis
|
Du, Meng-ge |
|
|
298 |
11 |
p. |
artikel |
20 |
Correction: Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells
|
He, Songwei |
|
|
298 |
11 |
p. |
artikel |
21 |
Correction: Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom
|
Song, Yu |
|
|
298 |
11 |
p. |
artikel |
22 |
Correction: Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains
|
Zhang, Ning |
|
|
298 |
11 |
p. |
artikel |
23 |
Cover
|
|
|
|
298 |
11 |
p. |
artikel |
24 |
Death domain–associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT
|
Ishikura, Shuhei |
|
|
298 |
11 |
p. |
artikel |
25 |
“Disruption of the molecular clock severely affects lipid metabolism in a hepatocellular carcinoma cell model”
|
Monjes, Natalia M. |
|
|
298 |
11 |
p. |
artikel |
26 |
Dissipation of the proton electrochemical gradient in chloroplasts promotes the oxidation of ATP synthase by thioredoxin-like proteins
|
Sekiguchi, Takatoshi |
|
|
298 |
11 |
p. |
artikel |
27 |
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein
|
Dhakal, Shailendra |
|
|
298 |
11 |
p. |
artikel |
28 |
DNA-mediated proteolysis by neutrophil elastase enhances binding activities of the HMGB1 protein
|
Wang, Xi |
|
|
298 |
11 |
p. |
artikel |
29 |
Eisosome protein Pil1 regulates mitochondrial morphology, mitophagy, and cell death in Saccharomyces cerevisiae
|
Pal, Amita |
|
|
298 |
11 |
p. |
artikel |
30 |
Elucidation of the substrate of tRNA-modifying enzymes MnmEG leads to in vitro reconstitution of an evolutionarily conserved uridine hypermodification
|
Bommisetti, Praneeth |
|
|
298 |
11 |
p. |
artikel |
31 |
Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890
|
Randolph, Clinita E. |
|
|
298 |
11 |
p. |
artikel |
32 |
Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA
|
Britton, Brooke M. |
|
|
298 |
11 |
p. |
artikel |
33 |
Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay
|
Embree, Caleb M. |
|
|
298 |
11 |
p. |
artikel |
34 |
Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model
|
Saunders, Justin M. |
|
|
298 |
11 |
p. |
artikel |
35 |
Glycosyltransferases EXTL2 and EXTL3 cellular balance dictates heparan sulfate biosynthesis and shapes gastric cancer cell motility and invasion
|
Marques, Catarina |
|
|
298 |
11 |
p. |
artikel |
36 |
Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures
|
Belachew, Binyam |
|
|
298 |
11 |
p. |
artikel |
37 |
Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the interorganelle transport protein CERT
|
Benedyk, Tomasz H. |
|
|
298 |
11 |
p. |
artikel |
38 |
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis
|
Kotani, Norihiro |
|
|
298 |
11 |
p. |
artikel |
39 |
Improved mammalian retromer cryo-EM structures reveal a new assembly interface
|
Kendall, Amy K. |
|
|
298 |
11 |
p. |
artikel |
40 |
Inner membrane YfgM–PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation
|
Miyazaki, Ryoji |
|
|
298 |
11 |
p. |
artikel |
41 |
Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates
|
Kuhlmann, F. Matthew |
|
|
298 |
11 |
p. |
artikel |
42 |
Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens
|
Quinlan, Roy A. |
|
|
298 |
11 |
p. |
artikel |
43 |
Integrated proteomics identifies PARP inhibitor-induced prosurvival signaling changes as potential vulnerabilities in ovarian cancer
|
Deng, Ou |
|
|
298 |
11 |
p. |
artikel |
44 |
Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation
|
Martinez, Chloe-Anne |
|
|
298 |
11 |
p. |
artikel |
45 |
Isocitrate binds to the itaconic acid–responsive LysR-type transcriptional regulator RipR in Salmonella pathogenesis
|
Ki, Nayeon |
|
|
298 |
11 |
p. |
artikel |
46 |
Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids
|
Noguchi, Makoto |
|
|
298 |
11 |
p. |
artikel |
47 |
Large Rab GTPase Rab44 regulates microtubule-dependent retrograde melanosome transport in melanocytes
|
Maruta, Yuto |
|
|
298 |
11 |
p. |
artikel |
48 |
Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca2+ ATPase uncoupling in muscle
|
Geromella, Mia S. |
|
|
298 |
11 |
p. |
artikel |
49 |
m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells
|
Suphakhong, Kusuma |
|
|
298 |
11 |
p. |
artikel |
50 |
MicroRNA-16 inhibits the TLR4/NF-κB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea
|
Xi, Meijuan |
|
|
298 |
11 |
p. |
artikel |
51 |
Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold
|
Lorente Cobo, Neil |
|
|
298 |
11 |
p. |
artikel |
52 |
MqsR is a noncanonical microbial RNase toxin that is inhibited by antitoxin MqsA via steric blockage of substrate binding
|
Yu, Victor |
|
|
298 |
11 |
p. |
artikel |
53 |
Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
|
Murach, Kevin A. |
|
|
298 |
11 |
p. |
artikel |
54 |
Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability
|
Shukla, Prakash K. |
|
|
298 |
11 |
p. |
artikel |
55 |
Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly
|
Diaz-Parga, Pedro |
|
|
298 |
11 |
p. |
artikel |
56 |
Natural polyphenols convert proteins into histone-binding ligands
|
Yamaguchi, Kosuke |
|
|
298 |
11 |
p. |
artikel |
57 |
N-terminal acetylation and arginylation of actin determines the architecture and assembly rate of linear and branched actin networks
|
Chin, Samantha M. |
|
|
298 |
11 |
p. |
artikel |
58 |
Outer surface lipoproteins from the Lyme disease spirochete exploit the molecular switch mechanism of the complement protease C1s
|
Garrigues, Ryan J. |
|
|
298 |
11 |
p. |
artikel |
59 |
Oxidative stress–induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain
|
Rocco-Machado, Nathália |
|
|
298 |
11 |
p. |
artikel |
60 |
Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains
|
Lee, Pei Wen |
|
|
298 |
11 |
p. |
artikel |
61 |
Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function
|
Fallon, Ciara M. |
|
|
298 |
11 |
p. |
artikel |
62 |
Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions
|
Shaik, Gouse M. |
|
|
298 |
11 |
p. |
artikel |
63 |
Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity
|
Franco-Echevarría, Elsa |
|
|
298 |
11 |
p. |
artikel |
64 |
Precise and simultaneous quantification of mitochondrial DNA heteroplasmy and copy number by digital PCR
|
Shoop, Wendy K. |
|
|
298 |
11 |
p. |
artikel |
65 |
Protein arginine methyltransferase 1 in the generation of immune megakaryocytes: A perspective review
|
Zhao, Xinyang |
|
|
298 |
11 |
p. |
artikel |
66 |
Protein tyrosine kinase 6 regulates activation of SRC kinase
|
Alwanian, Wanian M. |
|
|
298 |
11 |
p. |
artikel |
67 |
Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules
|
Meyer, Mark B. |
|
|
298 |
11 |
p. |
artikel |
68 |
Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
|
Bao, Letian |
|
|
298 |
11 |
p. |
artikel |
69 |
Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation
|
Carlson, Christopher R. |
|
|
298 |
11 |
p. |
artikel |
70 |
Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα
|
Ayombil, Francis |
|
|
298 |
11 |
p. |
artikel |
71 |
SARS-CoV-2 hijacks macropinocytosis to facilitate its entry and promote viral spike–mediated cell-to-cell fusion
|
Zhang, Yu-Yuan |
|
|
298 |
11 |
p. |
artikel |
72 |
Seq’ing the origins of cells in the developing spinal cord
|
Rajebhosale, Prithviraj |
|
|
298 |
11 |
p. |
artikel |
73 |
Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability
|
Iwahori, Satoko |
|
|
298 |
11 |
p. |
artikel |
74 |
Structural and functional studies of Arabidopsis thaliana triphosphate tunnel metalloenzymes reveal roles for additional domains
|
Pesquera, Marta |
|
|
298 |
11 |
p. |
artikel |
75 |
Structural model for ligand binding and channel opening of an insect gustatory receptor
|
Morinaga, Satoshi |
|
|
298 |
11 |
p. |
artikel |
76 |
Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action
|
Weinhäupl, Katharina |
|
|
298 |
11 |
p. |
artikel |
77 |
α-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25α
|
Borland, Helena |
|
|
298 |
11 |
p. |
artikel |
78 |
The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis
|
Endo, Makoto |
|
|
298 |
11 |
p. |
artikel |
79 |
The ChaC family of γ-glutamyl cyclotransferases is required for Leishmania to switch to a slow growth state and for long-term survival of the parasite
|
Das, Sumit |
|
|
298 |
11 |
p. |
artikel |
80 |
The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling
|
Gayen, Manoshi |
|
|
298 |
11 |
p. |
artikel |
81 |
The extracellular domain of site-2-metalloprotease RseP is important for sensitivity to bacteriocin EntK1
|
Kristensen, Sofie S. |
|
|
298 |
11 |
p. |
artikel |
82 |
The ganglioside GM1a functions as a coreceptor/attachment factor for dengue virus during infection
|
Tantirimudalige, Sarala Neomi |
|
|
298 |
11 |
p. |
artikel |
83 |
The major trimeric antenna complexes serve as a site for qH-energy dissipation in plants
|
Bru, Pierrick |
|
|
298 |
11 |
p. |
artikel |
84 |
The N-terminal disease–associated R5L Tau mutation increases microtubule shrinkage rate due to disruption of microtubule-bound Tau patches
|
Cario, Alisa |
|
|
298 |
11 |
p. |
artikel |
85 |
The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice
|
Wang, Xiaoxin X. |
|
|
298 |
11 |
p. |
artikel |
86 |
The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation
|
Leitgeb, Urban |
|
|
298 |
11 |
p. |
artikel |
87 |
Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural–biological analysis
|
Selinger, Martin |
|
|
298 |
11 |
p. |
artikel |
88 |
Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells
|
Koizumi, Maria |
|
|
298 |
11 |
p. |
artikel |
89 |
Transcription suppression is mediated by the HDAC1–Sin3 complex in Xenopus nucleoplasmic extract
|
Quaas, Colleen E. |
|
|
298 |
11 |
p. |
artikel |
90 |
Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes
|
Miyata, Yugo |
|
|
298 |
11 |
p. |
artikel |
91 |
Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates
|
Schneider, Kara L. |
|
|
298 |
11 |
p. |
artikel |
92 |
Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway
|
Liang, Junrong |
|
|
298 |
11 |
p. |
artikel |