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                             92 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A dedicated C-6 β-hydroxyacyltransferase required for biosynthesis of the glycolipid anchor for Vi antigen capsule in typhoidal Salmonella Liston, S.D.

298 11 p.
artikel
2 Aging-associated REGγ proteasome decline predisposes to tauopathy Tu, Jialu

298 11 p.
artikel
3 Ancestral archaea expanded the genetic code with pyrrolysine Guo, Li-Tao

298 11 p.
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4 Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death Shrestha, Shikshya

298 11 p.
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5 Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage Gao, Zhengyu

298 11 p.
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6 A programmable system to methylate and demethylate N 6-methyladenosine (m6A) on specific RNA transcripts in mammalian cells Chang, Chen

298 11 p.
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7 Artificial pore blocker acts specifically on voltage-gated potassium channel isoform KV1.6 Gigolaev, Andrei M.

298 11 p.
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8 Aurora A–mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression Jiang, Ya

298 11 p.
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9 Bacterial conversion of a host weapon into a nutritional signal Valvano, Miguel A.

298 11 p.
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10 Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists Irwin, Sean

298 11 p.
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11 BTK kinase activity is dispensable for the survival of diffuse large B-cell lymphoma Yuan, Hongwei

298 11 p.
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12 Cell adhesion molecule CD44v10 promotes stem-like properties in triple-negative breast cancer cells via glucose transporter GLUT1-mediated glycolysis Guo, Qian

298 11 p.
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13 Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation Wang, Hongrui

298 11 p.
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14 Computational and functional studies of the PI(4,5)P2 binding site of the TRPM3 ion channel reveal interactions with other regulators Zhao, Siyuan

298 11 p.
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15 Cooperative assembly of filopodia by the formin FMNL2 and I-BAR domain protein IRTKS Fox, Sarah

298 11 p.
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16 Coprinopsis cinerea dioxygenase is an oxygenase forming 10(S)-hydroperoxide of linoleic acid, essential for mushroom alcohol, 1-octen-3-ol, synthesis Teshima, Takuya

298 11 p.
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17 Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion Sparks, Robert P.

298 11 p.
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18 Correction: CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA Su, Guangsong

298 11 p.
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19 Correction: Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis Du, Meng-ge

298 11 p.
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20 Correction: Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells He, Songwei

298 11 p.
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21 Correction: Sj7170, a unique dual-function peptide with a specific α-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom Song, Yu

298 11 p.
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22 Correction: Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains Zhang, Ning

298 11 p.
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23 Cover
298 11 p.
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24 Death domain–associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT Ishikura, Shuhei

298 11 p.
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25 “Disruption of the molecular clock severely affects lipid metabolism in a hepatocellular carcinoma cell model” Monjes, Natalia M.

298 11 p.
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26 Dissipation of the proton electrochemical gradient in chloroplasts promotes the oxidation of ATP synthase by thioredoxin-like proteins Sekiguchi, Takatoshi

298 11 p.
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27 Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein Dhakal, Shailendra

298 11 p.
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28 DNA-mediated proteolysis by neutrophil elastase enhances binding activities of the HMGB1 protein Wang, Xi

298 11 p.
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29 Eisosome protein Pil1 regulates mitochondrial morphology, mitophagy, and cell death in Saccharomyces cerevisiae Pal, Amita

298 11 p.
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30 Elucidation of the substrate of tRNA-modifying enzymes MnmEG leads to in vitro reconstitution of an evolutionarily conserved uridine hypermodification Bommisetti, Praneeth

298 11 p.
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31 Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890 Randolph, Clinita E.

298 11 p.
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32 Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA Britton, Brooke M.

298 11 p.
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33 Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay Embree, Caleb M.

298 11 p.
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34 Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model Saunders, Justin M.

298 11 p.
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35 Glycosyltransferases EXTL2 and EXTL3 cellular balance dictates heparan sulfate biosynthesis and shapes gastric cancer cell motility and invasion Marques, Catarina

298 11 p.
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36 Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures Belachew, Binyam

298 11 p.
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37 Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the interorganelle transport protein CERT Benedyk, Tomasz H.

298 11 p.
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38 Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis Kotani, Norihiro

298 11 p.
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39 Improved mammalian retromer cryo-EM structures reveal a new assembly interface Kendall, Amy K.

298 11 p.
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40 Inner membrane YfgM–PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation Miyazaki, Ryoji

298 11 p.
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41 Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates Kuhlmann, F. Matthew

298 11 p.
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42 Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens Quinlan, Roy A.

298 11 p.
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43 Integrated proteomics identifies PARP inhibitor-induced prosurvival signaling changes as potential vulnerabilities in ovarian cancer Deng, Ou

298 11 p.
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44 Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation Martinez, Chloe-Anne

298 11 p.
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45 Isocitrate binds to the itaconic acid–responsive LysR-type transcriptional regulator RipR in Salmonella pathogenesis Ki, Nayeon

298 11 p.
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46 Lactic acid bacteria–derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids Noguchi, Makoto

298 11 p.
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47 Large Rab GTPase Rab44 regulates microtubule-dependent retrograde melanosome transport in melanocytes Maruta, Yuto

298 11 p.
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48 Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca2+ ATPase uncoupling in muscle Geromella, Mia S.

298 11 p.
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49 m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells Suphakhong, Kusuma

298 11 p.
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50 MicroRNA-16 inhibits the TLR4/NF-κB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea Xi, Meijuan

298 11 p.
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51 Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold Lorente Cobo, Neil

298 11 p.
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52 MqsR is a noncanonical microbial RNase toxin that is inhibited by antitoxin MqsA via steric blockage of substrate binding Yu, Victor

298 11 p.
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53 Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks Murach, Kevin A.

298 11 p.
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54 Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability Shukla, Prakash K.

298 11 p.
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55 Natural and engineered inflammasome adapter proteins reveal optimum linker length for self-assembly Diaz-Parga, Pedro

298 11 p.
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56 Natural polyphenols convert proteins into histone-binding ligands Yamaguchi, Kosuke

298 11 p.
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57 N-terminal acetylation and arginylation of actin determines the architecture and assembly rate of linear and branched actin networks Chin, Samantha M.

298 11 p.
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58 Outer surface lipoproteins from the Lyme disease spirochete exploit the molecular switch mechanism of the complement protease C1s Garrigues, Ryan J.

298 11 p.
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59 Oxidative stress–induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain Rocco-Machado, Nathália

298 11 p.
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60 Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains Lee, Pei Wen

298 11 p.
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61 Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function Fallon, Ciara M.

298 11 p.
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62 Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions Shaik, Gouse M.

298 11 p.
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63 Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity Franco-Echevarría, Elsa

298 11 p.
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64 Precise and simultaneous quantification of mitochondrial DNA heteroplasmy and copy number by digital PCR Shoop, Wendy K.

298 11 p.
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65 Protein arginine methyltransferase 1 in the generation of immune megakaryocytes: A perspective review Zhao, Xinyang

298 11 p.
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66 Protein tyrosine kinase 6 regulates activation of SRC kinase Alwanian, Wanian M.

298 11 p.
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67 Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules Meyer, Mark B.

298 11 p.
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68 Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation Bao, Letian

298 11 p.
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69 Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation Carlson, Christopher R.

298 11 p.
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70 Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα Ayombil, Francis

298 11 p.
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71 SARS-CoV-2 hijacks macropinocytosis to facilitate its entry and promote viral spike–mediated cell-to-cell fusion Zhang, Yu-Yuan

298 11 p.
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72 Seq’ing the origins of cells in the developing spinal cord Rajebhosale, Prithviraj

298 11 p.
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73 Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability Iwahori, Satoko

298 11 p.
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74 Structural and functional studies of Arabidopsis thaliana triphosphate tunnel metalloenzymes reveal roles for additional domains Pesquera, Marta

298 11 p.
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75 Structural model for ligand binding and channel opening of an insect gustatory receptor Morinaga, Satoshi

298 11 p.
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76 Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action Weinhäupl, Katharina

298 11 p.
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77 α-synuclein buildup is alleviated via ESCRT-dependent endosomal degradation brought about by p38MAPK inhibition in cells expressing p25α Borland, Helena

298 11 p.
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78 The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis Endo, Makoto

298 11 p.
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79 The ChaC family of γ-glutamyl cyclotransferases is required for Leishmania to switch to a slow growth state and for long-term survival of the parasite Das, Sumit

298 11 p.
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80 The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling Gayen, Manoshi

298 11 p.
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81 The extracellular domain of site-2-metalloprotease RseP is important for sensitivity to bacteriocin EntK1 Kristensen, Sofie S.

298 11 p.
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82 The ganglioside GM1a functions as a coreceptor/attachment factor for dengue virus during infection Tantirimudalige, Sarala Neomi

298 11 p.
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83 The major trimeric antenna complexes serve as a site for qH-energy dissipation in plants Bru, Pierrick

298 11 p.
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84 The N-terminal disease–associated R5L Tau mutation increases microtubule shrinkage rate due to disruption of microtubule-bound Tau patches Cario, Alisa

298 11 p.
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85 The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice Wang, Xiaoxin X.

298 11 p.
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86 The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation Leitgeb, Urban

298 11 p.
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87 Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural–biological analysis Selinger, Martin

298 11 p.
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88 Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells Koizumi, Maria

298 11 p.
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89 Transcription suppression is mediated by the HDAC1–Sin3 complex in Xenopus nucleoplasmic extract Quaas, Colleen E.

298 11 p.
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90 Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes Miyata, Yugo

298 11 p.
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91 Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates Schneider, Kara L.

298 11 p.
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92 Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway Liang, Junrong

298 11 p.
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                             92 gevonden resultaten
 
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