nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A bona fide MAP kinase
|
Oldach, Laurel |
|
|
298 |
10 |
p. |
artikel |
2 |
A cathelicidin antimicrobial peptide from Hydrophis cyanocinctus inhibits Zika virus infection by downregulating expression of a viral entry factor
|
Wang, Jing |
|
|
298 |
10 |
p. |
artikel |
3 |
A conserved loop sequence of the proteasome system depupylase Dop regulates substrate selectivity in Mycobacterium tuberculosis
|
Yoo, Jin Hee |
|
|
298 |
10 |
p. |
artikel |
4 |
A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus
|
Tan, Stephanie |
|
|
298 |
10 |
p. |
artikel |
5 |
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans
|
Wizrah, Maha S.I. |
|
|
298 |
10 |
p. |
artikel |
6 |
AI protein structure prediction-based modeling and mutagenesis of a protostome receptor and peptide ligands reveal key residues for their interaction
|
Guo, Shi-Qi |
|
|
298 |
10 |
p. |
artikel |
7 |
Alkaline-sensitive two-pore domain potassium channels form functional heteromers in pancreatic β-cells
|
Khoubza, Lamyaa |
|
|
298 |
10 |
p. |
artikel |
8 |
An ELISA-based platform for rapid identification of structure-dependent nucleic acid–protein interactions detects novel DNA triplex interactors
|
Economos, Nicholas G. |
|
|
298 |
10 |
p. |
artikel |
9 |
An evolutionary divergent thermodynamic brake in ZAP-70 fine-tunes the kinetic proofreading in T cells
|
Gangopadhyay, Kaustav |
|
|
298 |
10 |
p. |
artikel |
10 |
A novel Tetrahymena thermophila sterol C-22 desaturase belongs to the fatty acid hydroxylase/desaturase superfamily
|
Sanchez Granel, María L. |
|
|
298 |
10 |
p. |
artikel |
11 |
A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond
|
Medley, Brendon J. |
|
|
298 |
10 |
p. |
artikel |
12 |
A shared, stochastic pathway mediates exosome protein budding along plasma and endosome membranes
|
Fordjour, Francis K. |
|
|
298 |
10 |
p. |
artikel |
13 |
Assembly-promoting protein Munc18c stimulates SNARE-dependent membrane fusion through its SNARE-like peptide
|
Liu, Furong |
|
|
298 |
10 |
p. |
artikel |
14 |
A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability
|
Koochaki, Sebastian H.J. |
|
|
298 |
10 |
p. |
artikel |
15 |
ATP-binding cassette protein ABCA7 deficiency impairs sphingomyelin synthesis, cognitive discrimination, and synaptic plasticity in the entorhinal cortex
|
Iqbal, Jahangir |
|
|
298 |
10 |
p. |
artikel |
16 |
Chloroplast envelope ATPase PGA1/AtFtsH12 is required for chloroplast protein accumulation and cytosol-chloroplast protein homeostasis in Arabidopsis
|
Li, Qinglong |
|
|
298 |
10 |
p. |
artikel |
17 |
Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching
|
Wei, Wei |
|
|
298 |
10 |
p. |
artikel |
18 |
Correction: Structural basis for the DNA-binding activity of human ARID4B Tudor domain
|
Ren, Jie |
|
|
298 |
10 |
p. |
artikel |
19 |
Correction: The mechanism of β-N-methylamino-L-alanine inhibition of tRNA aminoacylation and its impact on misincorporation
|
Han, Nien-Ching |
|
|
298 |
10 |
p. |
artikel |
20 |
Correction: Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium
|
Hazim, Roni A. |
|
|
298 |
10 |
p. |
artikel |
21 |
Correlated STORM-homoFRET imaging reveals highly heterogeneous membrane receptor structures
|
Driouchi, Amine |
|
|
298 |
10 |
p. |
artikel |
22 |
Covalent conjugation of ubiquitin-like ISG15 to apoptosis-inducing factor exacerbates toxic stimuli-induced apoptotic cell death
|
Jeon, Seo Jeong |
|
|
298 |
10 |
p. |
artikel |
23 |
Cover
|
|
|
|
298 |
10 |
p. |
artikel |
24 |
CRY–BARs: Versatile light-gated molecular tools for the remodeling of membrane architectures
|
Wurz, Anna I. |
|
|
298 |
10 |
p. |
artikel |
25 |
α-Crystallin chaperone mimetic drugs inhibit lens γ-crystallin aggregation: Potential role for cataract prevention
|
Islam, Sidra |
|
|
298 |
10 |
p. |
artikel |
26 |
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors
|
Saccoccia, Fulvio |
|
|
298 |
10 |
p. |
artikel |
27 |
Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3
|
Leighton, Gage O. |
|
|
298 |
10 |
p. |
artikel |
28 |
Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation
|
Salaun, Christine |
|
|
298 |
10 |
p. |
artikel |
29 |
Differential activity of mGlu7 allosteric modulators provides evidence for mGlu7/8 heterodimers at hippocampal Schaffer collateral-CA1 synapses
|
Lin, Xin |
|
|
298 |
10 |
p. |
artikel |
30 |
Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism
|
Pederick, Jordan L. |
|
|
298 |
10 |
p. |
artikel |
31 |
Distinct functions of dimeric and monomeric scaffold protein Alix in regulating F-actin assembly and loading of exosomal cargo
|
Qiu, Xiaohui |
|
|
298 |
10 |
p. |
artikel |
32 |
DNA methyltransferase DNMT3A forms interaction networks with the CpG site and flanking sequence elements for efficient methylation
|
Dukatz, Michael |
|
|
298 |
10 |
p. |
artikel |
33 |
Early stage β-amyloid-membrane interactions modulate lipid dynamics and influence structural interfaces and fibrillation
|
Kenyaga, June M. |
|
|
298 |
10 |
p. |
artikel |
34 |
Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress
|
Jaworek, Witold |
|
|
298 |
10 |
p. |
artikel |
35 |
Engineering functional thermostable proteins using ancestral sequence reconstruction
|
Thomson, Raine E.S. |
|
|
298 |
10 |
p. |
artikel |
36 |
ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence
|
Hirata, Tetsuya |
|
|
298 |
10 |
p. |
artikel |
37 |
Estradiol production of granulosa cells is unaffected by the physiological mix of nonesterified fatty acids in follicular fluid
|
Baddela, Vijay Simha |
|
|
298 |
10 |
p. |
artikel |
38 |
Evolution and molecular basis of substrate specificity in a 3-ketoacyl-CoA synthase gene cluster from Populus trichocarpa
|
Chen, Jeff Y. |
|
|
298 |
10 |
p. |
artikel |
39 |
Expression of myelin transcription factor 1 and lamin B receptor mediate neural progenitor fate transition in the zebrafish spinal cord pMN domain
|
Xing, Lingyan |
|
|
298 |
10 |
p. |
artikel |
40 |
Fluorescent detection of hydrogen sulfide (H2S) through the formation of pyrene excimers enhances H2S quantification in biochemical systems
|
Pose, Manuela |
|
|
298 |
10 |
p. |
artikel |
41 |
Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome
|
Al Khatib, Iman |
|
|
298 |
10 |
p. |
artikel |
42 |
GC × GC-TOFMS metabolomics analysis identifies elevated levels of plasma sugars and sugar alcohols in diabetic mellitus patients with kidney failure
|
Duangkumpha, Kassaporn |
|
|
298 |
10 |
p. |
artikel |
43 |
Glu289 residue in the pore-forming motif of Vibrio cholerae cytolysin is important for efficient β-barrel pore formation
|
Mondal, Anish Kumar |
|
|
298 |
10 |
p. |
artikel |
44 |
Glycosylation of a key cubilin Asn residue results in reduced binding to albumin
|
Yadav, Shiv Pratap Singh |
|
|
298 |
10 |
p. |
artikel |
45 |
GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral membrane and regulates epithelial apicobasal polarity
|
Sakurai, Tsubasa |
|
|
298 |
10 |
p. |
artikel |
46 |
G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin
|
Varney, Matthew J. |
|
|
298 |
10 |
p. |
artikel |
47 |
Hedgehog acyltransferase catalyzes a random sequential reaction and utilizes multiple fatty acyl-CoA substrates
|
Schonbrun, Adina R. |
|
|
298 |
10 |
p. |
artikel |
48 |
2022 Herbert Tabor Early Career Investigator Awards: Call for nominations
|
Farabaugh, Kenneth T. |
|
|
298 |
10 |
p. |
artikel |
49 |
High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding
|
Gnann, Andrew D. |
|
|
298 |
10 |
p. |
artikel |
50 |
Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth
|
Stewart, Tracy Murray |
|
|
298 |
10 |
p. |
artikel |
51 |
How an assembly factor enhances covalent FAD attachment to the flavoprotein subunit of complex II
|
Maklashina, Elena |
|
|
298 |
10 |
p. |
artikel |
52 |
Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA
|
Izidoro, Mario Servulo |
|
|
298 |
10 |
p. |
artikel |
53 |
Hyperactivation of the proteasome in Caenorhabditis elegans protects against proteotoxic stress and extends lifespan
|
Anderson, Raymond T. |
|
|
298 |
10 |
p. |
artikel |
54 |
Identification of lysophosphatidic acid in serum as a factor that promotes epithelial apical junctional complex organization
|
Sakakibara, Shotaro |
|
|
298 |
10 |
p. |
artikel |
55 |
Impaired Cdc20 signaling promotes senescence in normal cells and apoptosis in non–small cell lung cancer cells
|
Volonte, Daniela |
|
|
298 |
10 |
p. |
artikel |
56 |
Isc10, an inhibitor of the Smk1 MAPK, prevents activation loop autophosphorylation and substrate phosphorylation through separate mechanisms
|
Rimal, Abhimannyu |
|
|
298 |
10 |
p. |
artikel |
57 |
Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell–dependent tumor growth and metastasis in vivo
|
Su, Kevin |
|
|
298 |
10 |
p. |
artikel |
58 |
Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma
|
Chu, Tian-Huei |
|
|
298 |
10 |
p. |
artikel |
59 |
Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase
|
Anindita, Paulina Duhita |
|
|
298 |
10 |
p. |
artikel |
60 |
Metabolomics reveals inosine 5′-monophosphate is increased during mice adipocyte browning
|
Takahashi, Haruya |
|
|
298 |
10 |
p. |
artikel |
61 |
Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation
|
Pauly, Thomas |
|
|
298 |
10 |
p. |
artikel |
62 |
Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies
|
Temme, J. Sebastian |
|
|
298 |
10 |
p. |
artikel |
63 |
Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets
|
Bowler, Jeannette T. |
|
|
298 |
10 |
p. |
artikel |
64 |
Multi-OMICs analysis reveals metabolic and epigenetic changes associated with macrophage polarization
|
Sowers, Mark L. |
|
|
298 |
10 |
p. |
artikel |
65 |
New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain
|
Sander, Simon |
|
|
298 |
10 |
p. |
artikel |
66 |
N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase
|
Rosenau, Jana |
|
|
298 |
10 |
p. |
artikel |
67 |
Nontraditional translation is the key to UFMylation and beyond
|
Lin, Mengjia |
|
|
298 |
10 |
p. |
artikel |
68 |
Outer membrane vesicles as molecular biomarkers for Gram-negative sepsis: Taking advantage of nature’s perfect packages
|
Michel, Lea Vacca |
|
|
298 |
10 |
p. |
artikel |
69 |
Oxidation of two cysteines within yeast Hsp70 impairs proteostasis while directly triggering an Hsf1-dependent cytoprotective response
|
Santiago, Alec |
|
|
298 |
10 |
p. |
artikel |
70 |
Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice
|
Yenilmez, Batuhan |
|
|
298 |
10 |
p. |
artikel |
71 |
Peptide OM-LV20 protects astrocytes against oxidative stress via the ‘PAC1R/JNK/TPH1’ axis
|
Yin, Saige |
|
|
298 |
10 |
p. |
artikel |
72 |
Peristaltic pumps adapted for laminar flow experiments enhance in vitro modeling of vascular cell behavior
|
Abello, Javier |
|
|
298 |
10 |
p. |
artikel |
73 |
Phase-separation antagonists potently inhibit transcription and broadly increase nucleosome density
|
Meduri, Rajyalakshmi |
|
|
298 |
10 |
p. |
artikel |
74 |
Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery
|
Singh, Jayanti |
|
|
298 |
10 |
p. |
artikel |
75 |
Pore-forming moss protein bryoporin is structurally and mechanistically related to actinoporins from evolutionarily distant cnidarians
|
Šolinc, Gašper |
|
|
298 |
10 |
p. |
artikel |
76 |
PrkA is an ATP-dependent protease that regulates sporulation in Bacillus subtilis
|
Zhang, Ao |
|
|
298 |
10 |
p. |
artikel |
77 |
Proteasomal degradation of WT proinsulin in pancreatic beta cells
|
Xu, Xiaoxi |
|
|
298 |
10 |
p. |
artikel |
78 |
Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma
|
Li, Bingbing X. |
|
|
298 |
10 |
p. |
artikel |
79 |
Proto-oncogene FAM83A contributes to casein kinase 1–mediated mitochondrial maintenance and white adipocyte differentiation
|
Huang, Kuilong |
|
|
298 |
10 |
p. |
artikel |
80 |
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
|
Luciano, Amelia K. |
|
|
298 |
10 |
p. |
artikel |
81 |
Pyrvinium doubles against WNT-driven cancer
|
Fan, Jiaming |
|
|
298 |
10 |
p. |
artikel |
82 |
Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors
|
Wang, Ya-Juan |
|
|
298 |
10 |
p. |
artikel |
83 |
Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin
|
Ponde, Nicole O. |
|
|
298 |
10 |
p. |
artikel |
84 |
Recognition of extracellular DNA by type IV pili promotes biofilm formation by Clostridioides difficile
|
Ronish, Leslie A. |
|
|
298 |
10 |
p. |
artikel |
85 |
Sequential in vitro enzymatic N-glycoprotein modification reveals site-specific rates of glycoenzyme processing
|
Adams, Trevor M. |
|
|
298 |
10 |
p. |
artikel |
86 |
Single-channel characterization of the chitooligosaccharide transporter chitoporin (SmChiP) from the opportunistic pathogen Serratia marcescens
|
Soysa, H. Sasimali M. |
|
|
298 |
10 |
p. |
artikel |
87 |
Single molecule microscopy reveals diverse actions of substrate sequences that impair ClpX AAA+ ATPase function
|
Wang, Xiao |
|
|
298 |
10 |
p. |
artikel |
88 |
Specific phosphorylation of microtubule-associated protein 2c by extracellular signal–regulated kinase reduces interactions at its Pro-rich regions
|
Plucarová, Jitka |
|
|
298 |
10 |
p. |
artikel |
89 |
Still rocking in the structural era: A molecular overview of the small multidrug resistance (SMR) transporter family
|
Burata, Olive E. |
|
|
298 |
10 |
p. |
artikel |
90 |
Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction
|
Elamin, Tasneem |
|
|
298 |
10 |
p. |
artikel |
91 |
Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA
|
Luo, Jiwei |
|
|
298 |
10 |
p. |
artikel |
92 |
Structural variations and roles of rhamnose-rich cell wall polysaccharides in Gram-positive bacteria
|
Guérin, Hugo |
|
|
298 |
10 |
p. |
artikel |
93 |
Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition
|
Johnson, D. Alex |
|
|
298 |
10 |
p. |
artikel |
94 |
Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity
|
Aryal, Pramod |
|
|
298 |
10 |
p. |
artikel |
95 |
Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6
|
Bassett, Jacob |
|
|
298 |
10 |
p. |
artikel |
96 |
The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila
|
Dang, Tien T. |
|
|
298 |
10 |
p. |
artikel |
97 |
The atypical Rab GTPase associated with Parkinson’s disease, Rab29, is localized to membranes
|
Nagai-Ito, Yuki |
|
|
298 |
10 |
p. |
artikel |
98 |
The conformations and basal conformational dynamics of translocation factor SecDF vary with translocon SecYEG interaction
|
Weaver, D.R. |
|
|
298 |
10 |
p. |
artikel |
99 |
The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size
|
Zapata-Mercado, Elmer |
|
|
298 |
10 |
p. |
artikel |
100 |
The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity
|
Ricketts, M. Daniel |
|
|
298 |
10 |
p. |
artikel |
101 |
The histone deacetylases Rpd3 and Hst1 antagonistically regulate de novo NAD+ metabolism in the budding yeast Saccharomyces cerevisiae
|
Groth, Benjamin |
|
|
298 |
10 |
p. |
artikel |
102 |
The iron–sulfur cluster assembly (ISC) protein Iba57 executes a tetrahydrofolate-independent function in mitochondrial [4Fe–4S] protein maturation
|
Mühlenhoff, Ulrich |
|
|
298 |
10 |
p. |
artikel |
103 |
The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function
|
Klau, Leesa J. |
|
|
298 |
10 |
p. |
artikel |
104 |
The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane
|
Li, Mei-Ling |
|
|
298 |
10 |
p. |
artikel |
105 |
The SET-domain protein CgSet4 negatively regulates antifungal drug resistance via the ergosterol biosynthesis transcriptional regulator CgUpc2a
|
Bhakt, Priyanka |
|
|
298 |
10 |
p. |
artikel |
106 |
The transcription factor Cdx2 regulates inflammasome activity through expression of the NLRP3 suppressor TRIM31 to maintain intestinal homeostasis
|
Jahan, Sanzida |
|
|
298 |
10 |
p. |
artikel |
107 |
Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferases
|
Strassler, Sarah E. |
|
|
298 |
10 |
p. |
artikel |
108 |
Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin
|
Wu, Chunshuai |
|
|
298 |
10 |
p. |
artikel |
109 |
Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A
|
Liu, Yixin |
|
|
298 |
10 |
p. |
artikel |
110 |
Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu5a receptor internalization
|
van Senten, Jeffrey R. |
|
|
298 |
10 |
p. |
artikel |
111 |
Using T4 genetics and Laemmli’s development of high-resolution SDS gel electrophoresis to reveal structural protein interactions controlling protein folding and phage self-assembly
|
King, Jonathan |
|
|
298 |
10 |
p. |
artikel |
112 |
Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes
|
Hansen, Jens |
|
|
298 |
10 |
p. |
artikel |
113 |
Withdrawal: The chloroplast NAD(P)H dehydrogenase complex interacts with photosystem I in Arabidopsis
|
Peng, Lianwei |
|
|
298 |
10 |
p. |
artikel |