no |
title |
author |
magazine |
year |
volume |
issue |
page(s) |
type |
1 |
AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation
|
Caffrey, Brian |
|
|
297 |
4 |
p. |
article |
2 |
A C terminus–dependent conformational change is required for HDAC3 activation by nuclear receptor corepressors
|
Li, Jian |
|
|
297 |
4 |
p. |
article |
3 |
Activation of the cytosolic calcium-independent phospholipase A2 β isoform contributes to TRPC6 externalization via release of arachidonic acid
|
Putta, Priya |
|
|
297 |
4 |
p. |
article |
4 |
Activity-dependent release of phosphorylated human tau from Drosophila neurons in primary culture
|
Ismael, Sazan |
|
|
297 |
4 |
p. |
article |
5 |
Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca2+–calmodulin binding
|
Amini, Mahnaz |
|
|
297 |
4 |
p. |
article |
6 |
ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium
|
Ma, Xiang |
|
|
297 |
4 |
p. |
article |
7 |
A fully reversible 25-hydroxy steroid kinase involved in oxygen-independent cholesterol side-chain oxidation
|
Jacoby, Christian |
|
|
297 |
4 |
p. |
article |
8 |
Aim32 is a dual-localized 2Fe-2S mitochondrial protein that functions in redox quality control
|
Zhang, Danyun |
|
|
297 |
4 |
p. |
article |
9 |
Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation
|
Kazyken, D. |
|
|
297 |
4 |
p. |
article |
10 |
An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15
|
Perry, Jason K. |
|
|
297 |
4 |
p. |
article |
11 |
A new carbohydrate-active oligosaccharide dehydratase is involved in the degradation of ulvan
|
Bäumgen, Marcus |
|
|
297 |
4 |
p. |
article |
12 |
An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors
|
Lin, Jing-Yu |
|
|
297 |
4 |
p. |
article |
13 |
Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin
|
Susan-Resiga, Delia |
|
|
297 |
4 |
p. |
article |
14 |
A solid-supported membrane electrophysiology assay for efficient characterization of ion-coupled transport
|
Thomas, Nathan E. |
|
|
297 |
4 |
p. |
article |
15 |
A Split-Cre system designed to detect simultaneous expression of two genes based on SpyTag/SpyCatcher conjugation and Split-GFP dimerization
|
Wei, Xundong |
|
|
297 |
4 |
p. |
article |
16 |
A Trypanosoma brucei β3 glycosyltransferase superfamily gene encodes a β1-6 GlcNAc-transferase mediating N-glycan and GPI anchor modification
|
Duncan, Samuel M. |
|
|
297 |
4 |
p. |
article |
17 |
Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14
|
Enríquez, Paul |
|
|
297 |
4 |
p. |
article |
18 |
Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission
|
Luo, Xiaoyu |
|
|
297 |
4 |
p. |
article |
19 |
Calmodulin acetylation: A modification to remember
|
Sugimoto, Chiho |
|
|
297 |
4 |
p. |
article |
20 |
Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation
|
Glass, Sarah M. |
|
|
297 |
4 |
p. |
article |
21 |
CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA
|
Ishikura, Shuhei |
|
|
297 |
4 |
p. |
article |
22 |
Characterization of the specific DNA-binding properties of Tnp26, the transposase of insertion sequence IS26
|
Pong, Carol H. |
|
|
297 |
4 |
p. |
article |
23 |
Characterization of the transactivation and nuclear localization functions of Pichia pastoris zinc finger transcription factor Mxr1p
|
Gupta, Aditi |
|
|
297 |
4 |
p. |
article |
24 |
Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action
|
Eren, Elif |
|
|
297 |
4 |
p. |
article |
25 |
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity
|
Ercig, Bogac |
|
|
297 |
4 |
p. |
article |
26 |
Correction: Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages
|
Yao, Zhenyu |
|
|
297 |
4 |
p. |
article |
27 |
Correction: Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein–Barr virus infection
|
Dai, Dan-Ling |
|
|
297 |
4 |
p. |
article |
28 |
Correction: Potentiation of tumor necrosis factor-α-induced tumor cell apoptosis by a small molecule inhibitor for anti-apoptotic protein hPEBP4
|
Qiu, Jianming |
|
|
297 |
4 |
p. |
article |
29 |
Cover
|
|
|
|
297 |
4 |
p. |
article |
30 |
Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor
|
Wang, Yifan |
|
|
297 |
4 |
p. |
article |
31 |
Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif
|
Lorenzo, Ramiro |
|
|
297 |
4 |
p. |
article |
32 |
Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics
|
Gupta, Arnav |
|
|
297 |
4 |
p. |
article |
33 |
Democratizing calcium visualization
|
Oldach, Laurel |
|
|
297 |
4 |
p. |
article |
34 |
D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation
|
Yang, Tzu-Jing |
|
|
297 |
4 |
p. |
article |
35 |
Dietary lysine restriction induces lipid accumulation in skeletal muscle through an increase in serum threonine levels in rats
|
Goda, Yuki |
|
|
297 |
4 |
p. |
article |
36 |
Direct detection of the myosin super-relaxed state and interacting-heads motif in solution
|
Chu, Sami |
|
|
297 |
4 |
p. |
article |
37 |
Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis
|
Li, Bin |
|
|
297 |
4 |
p. |
article |
38 |
Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response
|
Jin, Danni |
|
|
297 |
4 |
p. |
article |
39 |
DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
|
Waldrip, Zachary J. |
|
|
297 |
4 |
p. |
article |
40 |
DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington’s disease via insertion sequences of its catalytic domain
|
Chan, Kara Y. |
|
|
297 |
4 |
p. |
article |
41 |
DNA polymerases η and κ bypass N 2-guanine-O 6-alkylguanine DNA alkyltransferase cross-linked DNA-peptides
|
Ghodke, Pratibha P. |
|
|
297 |
4 |
p. |
article |
42 |
Dynamic interplay of two molecular switches enabled by the MEK1/2–ERK1/2 and IL-6–STAT3 signaling axes controls epithelial cell migration in response to growth factors
|
Qin, Lyugao |
|
|
297 |
4 |
p. |
article |
43 |
Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics
|
King, William T. |
|
|
297 |
4 |
p. |
article |
44 |
ECHDC1 knockout mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism
|
Dewulf, Joseph P. |
|
|
297 |
4 |
p. |
article |
45 |
Enzymology and significance of protein histidine methylation
|
Jakobsson, Magnus E. |
|
|
297 |
4 |
p. |
article |
46 |
FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX
|
Manne, Rajesh Kumar |
|
|
297 |
4 |
p. |
article |
47 |
From OCR and ECAR to energy: Perspectives on the design and interpretation of bioenergetics studies
|
Schmidt, Cameron A. |
|
|
297 |
4 |
p. |
article |
48 |
Gene body methylation safeguards ribosomal DNA transcription by preventing PHF6-mediated enrichment of repressive histone mark H4K20me3
|
Huang, Xiaoke |
|
|
297 |
4 |
p. |
article |
49 |
Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression
|
Das, Priya |
|
|
297 |
4 |
p. |
article |
50 |
GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6
|
Yang, Pei-Lin |
|
|
297 |
4 |
p. |
article |
51 |
Human DIMT1 generates N 2 6,6A-dimethylation–containing small RNAs
|
Shen, Hui |
|
|
297 |
4 |
p. |
article |
52 |
Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2
|
Prévost, Jérémie |
|
|
297 |
4 |
p. |
article |
53 |
In silico and in vitro analysis of an Aspergillus niger chitin deacetylase to decipher its subsite sugar preferences
|
Bonin, Martin |
|
|
297 |
4 |
p. |
article |
54 |
Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis
|
Fisher, Allison L. |
|
|
297 |
4 |
p. |
article |
55 |
Linking nuclear matrix–localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z
|
Chen, Zhaosu |
|
|
297 |
4 |
p. |
article |
56 |
LPA1-mediated PKD2 activation promotes LPA-induced tissue factor expression via the p38α and JNK2 MAPK pathways in smooth muscle cells
|
Hao, Feng |
|
|
297 |
4 |
p. |
article |
57 |
Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I
|
Liu, Ge |
|
|
297 |
4 |
p. |
article |
58 |
Metabolic flexibility maintains proliferation and migration of FGFR signaling–deficient lymphatic endothelial cells
|
Song, Hongyuan |
|
|
297 |
4 |
p. |
article |
59 |
Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis
|
Pang, Huimin |
|
|
297 |
4 |
p. |
article |
60 |
Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage
|
Bubb, Kristina |
|
|
297 |
4 |
p. |
article |
61 |
Mitochondria–plasma membrane interactions and communication
|
Montes de Oca Balderas, Pavel |
|
|
297 |
4 |
p. |
article |
62 |
Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease
|
Li, Shanshan |
|
|
297 |
4 |
p. |
article |
63 |
Monitoring cellular redox dynamics using newly developed BRET-based redox sensor proteins
|
Fu, Nae |
|
|
297 |
4 |
p. |
article |
64 |
MS imaging of multicellular tumor spheroids and organoids as an emerging tool for personalized medicine and drug discovery
|
Wang, Yijia |
|
|
297 |
4 |
p. |
article |
65 |
Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state
|
Fenton, Benjamin A. |
|
|
297 |
4 |
p. |
article |
66 |
Myricetin slows liquid–liquid phase separation of Tau and activates ATG5-dependent autophagy to suppress Tau toxicity
|
Dai, Bin |
|
|
297 |
4 |
p. |
article |
67 |
N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
|
Currie, Michael J. |
|
|
297 |
4 |
p. |
article |
68 |
New strategies for targeting kinase networks in cancer
|
Yesilkanal, Ali E. |
|
|
297 |
4 |
p. |
article |
69 |
Novel human cell expression method reveals the role and prevalence of posttranslational modification in nonmuscle tropomyosins
|
Carman, Peter J. |
|
|
297 |
4 |
p. |
article |
70 |
Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P
|
Ma, Jianhong |
|
|
297 |
4 |
p. |
article |
71 |
Optimized expression and purification of adipose triglyceride lipase improved hydrolytic and transacylation activities in vitro
|
Kulminskaya, Natalia |
|
|
297 |
4 |
p. |
article |
72 |
Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization
|
Martin, Carly E. |
|
|
297 |
4 |
p. |
article |
73 |
Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils
|
Hughes, Michael P. |
|
|
297 |
4 |
p. |
article |
74 |
PROFICS: A bacterial selection system for directed evolution of proteases
|
Kröß, Christina |
|
|
297 |
4 |
p. |
article |
75 |
Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation
|
Pollecker, Karen |
|
|
297 |
4 |
p. |
article |
76 |
Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples
|
Ansari, Fariha |
|
|
297 |
4 |
p. |
article |
77 |
Rapid inactivation of the yeast Sec complex selectively blocks transport of post-translationally translocated proteins
|
Yi, Jae Kyo |
|
|
297 |
4 |
p. |
article |
78 |
Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells
|
Reijneveld, Josephine F. |
|
|
297 |
4 |
p. |
article |
79 |
Receptor binding, immune escape, and protein stability direct the natural selection of SARS-CoV-2 variants
|
Upadhyay, Vaibhav |
|
|
297 |
4 |
p. |
article |
80 |
Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase
|
Peshenko, Igor V. |
|
|
297 |
4 |
p. |
article |
81 |
RetS inhibits Pseudomonas aeruginosa biofilm formation by disrupting the canonical histidine kinase dimerization interface of GacS
|
Ryan Kaler, Kylie M. |
|
|
297 |
4 |
p. |
article |
82 |
Ribosylation of the CD8αβ heterodimer permits binding of the nonclassical major histocompatibility molecule, H2-Q10
|
Goodall, Katharine Jennifer |
|
|
297 |
4 |
p. |
article |
83 |
Role of substrate recognition in modulating strigolactone receptor selectivity in witchweed
|
Chen, Jiming |
|
|
297 |
4 |
p. |
article |
84 |
S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity
|
Puthenveetil, Robbins |
|
|
297 |
4 |
p. |
article |
85 |
SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity
|
Olia, Adam S. |
|
|
297 |
4 |
p. |
article |
86 |
Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β
|
Nies, Sarah Helena |
|
|
297 |
4 |
p. |
article |
87 |
Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity
|
Kim, Hyunsup |
|
|
297 |
4 |
p. |
article |
88 |
Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR
|
Gubensäk, Nina |
|
|
297 |
4 |
p. |
article |
89 |
Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins
|
Bowen, Nicole E. |
|
|
297 |
4 |
p. |
article |
90 |
Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1
|
Guo, Yusong |
|
|
297 |
4 |
p. |
article |
91 |
Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus
|
Madland, Eva |
|
|
297 |
4 |
p. |
article |
92 |
Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection
|
Dwivedi, Rohini |
|
|
297 |
4 |
p. |
article |
93 |
Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex
|
Liu, Weifeng |
|
|
297 |
4 |
p. |
article |
94 |
Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets
|
Chua, Sheena M.H. |
|
|
297 |
4 |
p. |
article |
95 |
Structural insights into the mechanism of pH-selective substrate specificity of the polysaccharide lyase Smlt1473
|
Pandey, Shubhant |
|
|
297 |
4 |
p. |
article |
96 |
Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis
|
Carr, Samuel C. |
|
|
297 |
4 |
p. |
article |
97 |
Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide–catabolizing nitroreductase from Sphingopyxis sp. strain HMH
|
Kim, Sang-Hoon |
|
|
297 |
4 |
p. |
article |
98 |
Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction
|
Ahmad, Javeed |
|
|
297 |
4 |
p. |
article |
99 |
TBK1 has a new Akt
|
Shaw, Leslie M. |
|
|
297 |
4 |
p. |
article |
100 |
TFEB insufficiency promotes cardiac hypertrophy by blocking autophagic degradation of GATA4
|
Song, Rui |
|
|
297 |
4 |
p. |
article |
101 |
TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters
|
Webb, Bryan M. |
|
|
297 |
4 |
p. |
article |
102 |
The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy
|
Gandelman, Mandi |
|
|
297 |
4 |
p. |
article |
103 |
The circular RNA circBCL2L1 regulates innate immune responses via microRNA-mediated downregulation of TRAF6 in teleost fish
|
Zheng, Weiwei |
|
|
297 |
4 |
p. |
article |
104 |
The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
|
Stromberg, Benjamin R. |
|
|
297 |
4 |
p. |
article |
105 |
The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium
|
Tamura, Isao |
|
|
297 |
4 |
p. |
article |
106 |
The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions
|
Gopalakrishnan, Rajaraman |
|
|
297 |
4 |
p. |
article |
107 |
The macromolecular complexes of histones affect protein arginine methyltransferase activities
|
Fulton, Melody D. |
|
|
297 |
4 |
p. |
article |
108 |
The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation
|
Yoast, Ryan E. |
|
|
297 |
4 |
p. |
article |
109 |
The periodic table of ribonucleotide reductases
|
Ruskoski, Terry B. |
|
|
297 |
4 |
p. |
article |
110 |
The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene
|
Mori, Kohji |
|
|
297 |
4 |
p. |
article |
111 |
The predicted stem-loop structure in the 3′-end of the human norovirus antigenomic sequence is required for its genomic RNA synthesis by its RdRp
|
Shimoike, Takashi |
|
|
297 |
4 |
p. |
article |
112 |
The receptor-type protein tyrosine phosphatase CD45 promotes onset and severity of IL-1β–mediated autoinflammatory osteomyelitis
|
Kralova, Jarmila |
|
|
297 |
4 |
p. |
article |
113 |
The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels
|
Chen, Xu |
|
|
297 |
4 |
p. |
article |
114 |
The transcription factor Tfcp2l1 promotes primordial germ cell–like cell specification of pluripotent stem cells
|
Zhang, Meng |
|
|
297 |
4 |
p. |
article |
115 |
The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids
|
Frankovsky, Jan |
|
|
297 |
4 |
p. |
article |
116 |
Titratable transmembrane residues and a hydrophobic plug are essential for manganese import via the Bacillus anthracis ABC transporter MntBC-A
|
Kuznetsova, Anastasiya |
|
|
297 |
4 |
p. |
article |
117 |
Topological analyses of the L-lysine exporter LysO reveal a critical role for a conserved pair of intramembrane solvent-exposed acidic residues
|
Dubey, Swati |
|
|
297 |
4 |
p. |
article |
118 |
Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro
|
Nguyen, Phong Quoc |
|
|
297 |
4 |
p. |
article |
119 |
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid
|
Zhao, Yang |
|
|
297 |
4 |
p. |
article |
120 |
USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates
|
Zhang, Fengwu |
|
|
297 |
4 |
p. |
article |
121 |
Valproate activates the Snf1 kinase in Saccharomyces cerevisiae by decreasing the cytosolic pH
|
Salsaa, Michael |
|
|
297 |
4 |
p. |
article |
122 |
Vitamin D signaling inhibits HBV activity by directly targeting the HBV core promoter
|
Ahluwalia, Shivaksh |
|
|
297 |
4 |
p. |
article |
123 |
Working toward reducing bias in peer review
|
Rye, Kerry-Anne |
|
|
297 |
4 |
p. |
article |