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                             123 results found
no title author magazine year volume issue page(s) type
1 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation Caffrey, Brian

297 4 p.
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2 A C terminus–dependent conformational change is required for HDAC3 activation by nuclear receptor corepressors Li, Jian

297 4 p.
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3 Activation of the cytosolic calcium-independent phospholipase A2 β isoform contributes to TRPC6 externalization via release of arachidonic acid Putta, Priya

297 4 p.
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4 Activity-dependent release of phosphorylated human tau from Drosophila neurons in primary culture Ismael, Sazan

297 4 p.
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5 Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca2+–calmodulin binding Amini, Mahnaz

297 4 p.
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6 ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium Ma, Xiang

297 4 p.
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7 A fully reversible 25-hydroxy steroid kinase involved in oxygen-independent cholesterol side-chain oxidation Jacoby, Christian

297 4 p.
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8 Aim32 is a dual-localized 2Fe-2S mitochondrial protein that functions in redox quality control Zhang, Danyun

297 4 p.
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9 Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation Kazyken, D.

297 4 p.
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10 An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15 Perry, Jason K.

297 4 p.
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11 A new carbohydrate-active oligosaccharide dehydratase is involved in the degradation of ulvan Bäumgen, Marcus

297 4 p.
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12 An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors Lin, Jing-Yu

297 4 p.
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13 Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin Susan-Resiga, Delia

297 4 p.
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14 A solid-supported membrane electrophysiology assay for efficient characterization of ion-coupled transport Thomas, Nathan E.

297 4 p.
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15 A Split-Cre system designed to detect simultaneous expression of two genes based on SpyTag/SpyCatcher conjugation and Split-GFP dimerization Wei, Xundong

297 4 p.
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16 A Trypanosoma brucei β3 glycosyltransferase superfamily gene encodes a β1-6 GlcNAc-transferase mediating N-glycan and GPI anchor modification Duncan, Samuel M.

297 4 p.
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17 Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14 Enríquez, Paul

297 4 p.
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18 Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission Luo, Xiaoyu

297 4 p.
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19 Calmodulin acetylation: A modification to remember Sugimoto, Chiho

297 4 p.
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20 Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation Glass, Sarah M.

297 4 p.
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21 CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA Ishikura, Shuhei

297 4 p.
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22 Characterization of the specific DNA-binding properties of Tnp26, the transposase of insertion sequence IS26 Pong, Carol H.

297 4 p.
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23 Characterization of the transactivation and nuclear localization functions of Pichia pastoris zinc finger transcription factor Mxr1p Gupta, Aditi

297 4 p.
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24 Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action Eren, Elif

297 4 p.
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25 Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity Ercig, Bogac

297 4 p.
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26 Correction: Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages Yao, Zhenyu

297 4 p.
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27 Correction: Identification of an N6-methyladenosine-mediated positive feedback loop that promotes Epstein–Barr virus infection Dai, Dan-Ling

297 4 p.
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28 Correction: Potentiation of tumor necrosis factor-α-induced tumor cell apoptosis by a small molecule inhibitor for anti-apoptotic protein hPEBP4 Qiu, Jianming

297 4 p.
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29 Cover
297 4 p.
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30 Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor Wang, Yifan

297 4 p.
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31 Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif Lorenzo, Ramiro

297 4 p.
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32 Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics Gupta, Arnav

297 4 p.
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33 Democratizing calcium visualization Oldach, Laurel

297 4 p.
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34 D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation Yang, Tzu-Jing

297 4 p.
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35 Dietary lysine restriction induces lipid accumulation in skeletal muscle through an increase in serum threonine levels in rats Goda, Yuki

297 4 p.
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36 Direct detection of the myosin super-relaxed state and interacting-heads motif in solution Chu, Sami

297 4 p.
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37 Discovery of ancestral L-ornithine and L-lysine decarboxylases reveals parallel, pseudoconvergent evolution of polyamine biosynthesis Li, Bin

297 4 p.
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38 Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response Jin, Danni

297 4 p.
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39 DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells Waldrip, Zachary J.

297 4 p.
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40 DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington’s disease via insertion sequences of its catalytic domain Chan, Kara Y.

297 4 p.
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41 DNA polymerases η and κ bypass N 2-guanine-O 6-alkylguanine DNA alkyltransferase cross-linked DNA-peptides Ghodke, Pratibha P.

297 4 p.
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42 Dynamic interplay of two molecular switches enabled by the MEK1/2–ERK1/2 and IL-6–STAT3 signaling axes controls epithelial cell migration in response to growth factors Qin, Lyugao

297 4 p.
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43 Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics King, William T.

297 4 p.
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44 ECHDC1 knockout mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism Dewulf, Joseph P.

297 4 p.
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45 Enzymology and significance of protein histidine methylation Jakobsson, Magnus E.

297 4 p.
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46 FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX Manne, Rajesh Kumar

297 4 p.
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47 From OCR and ECAR to energy: Perspectives on the design and interpretation of bioenergetics studies Schmidt, Cameron A.

297 4 p.
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48 Gene body methylation safeguards ribosomal DNA transcription by preventing PHF6-mediated enrichment of repressive histone mark H4K20me3 Huang, Xiaoke

297 4 p.
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49 Glyceraldehyde-3-phosphate dehydrogenase present in extracellular vesicles from Leishmania major suppresses host TNF-alpha expression Das, Priya

297 4 p.
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50 GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6 Yang, Pei-Lin

297 4 p.
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51 Human DIMT1 generates N 2 6,6A-dimethylation–containing small RNAs Shen, Hui

297 4 p.
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52 Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2 Prévost, Jérémie

297 4 p.
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53 In silico and in vitro analysis of an Aspergillus niger chitin deacetylase to decipher its subsite sugar preferences Bonin, Martin

297 4 p.
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54 Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis Fisher, Allison L.

297 4 p.
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55 Linking nuclear matrix–localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z Chen, Zhaosu

297 4 p.
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56 LPA1-mediated PKD2 activation promotes LPA-induced tissue factor expression via the p38α and JNK2 MAPK pathways in smooth muscle cells Hao, Feng

297 4 p.
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57 Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I Liu, Ge

297 4 p.
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58 Metabolic flexibility maintains proliferation and migration of FGFR signaling–deficient lymphatic endothelial cells Song, Hongyuan

297 4 p.
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59 Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis Pang, Huimin

297 4 p.
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60 Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage Bubb, Kristina

297 4 p.
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61 Mitochondria–plasma membrane interactions and communication Montes de Oca Balderas, Pavel

297 4 p.
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62 Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease Li, Shanshan

297 4 p.
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63 Monitoring cellular redox dynamics using newly developed BRET-based redox sensor proteins Fu, Nae

297 4 p.
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64 MS imaging of multicellular tumor spheroids and organoids as an emerging tool for personalized medicine and drug discovery Wang, Yijia

297 4 p.
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65 Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state Fenton, Benjamin A.

297 4 p.
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66 Myricetin slows liquid–liquid phase separation of Tau and activates ATG5-dependent autophagy to suppress Tau toxicity Dai, Bin

297 4 p.
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67 N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization Currie, Michael J.

297 4 p.
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68 New strategies for targeting kinase networks in cancer Yesilkanal, Ali E.

297 4 p.
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69 Novel human cell expression method reveals the role and prevalence of posttranslational modification in nonmuscle tropomyosins Carman, Peter J.

297 4 p.
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70 Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P Ma, Jianhong

297 4 p.
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71 Optimized expression and purification of adipose triglyceride lipase improved hydrolytic and transacylation activities in vitro Kulminskaya, Natalia

297 4 p.
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72 Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization Martin, Carly E.

297 4 p.
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73 Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils Hughes, Michael P.

297 4 p.
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74 PROFICS: A bacterial selection system for directed evolution of proteases Kröß, Christina

297 4 p.
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75 Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation Pollecker, Karen

297 4 p.
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76 Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples Ansari, Fariha

297 4 p.
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77 Rapid inactivation of the yeast Sec complex selectively blocks transport of post-translationally translocated proteins Yi, Jae Kyo

297 4 p.
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78 Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells Reijneveld, Josephine F.

297 4 p.
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79 Receptor binding, immune escape, and protein stability direct the natural selection of SARS-CoV-2 variants Upadhyay, Vaibhav

297 4 p.
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80 Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase Peshenko, Igor V.

297 4 p.
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81 RetS inhibits Pseudomonas aeruginosa biofilm formation by disrupting the canonical histidine kinase dimerization interface of GacS Ryan Kaler, Kylie M.

297 4 p.
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82 Ribosylation of the CD8αβ heterodimer permits binding of the nonclassical major histocompatibility molecule, H2-Q10 Goodall, Katharine Jennifer

297 4 p.
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83 Role of substrate recognition in modulating strigolactone receptor selectivity in witchweed Chen, Jiming

297 4 p.
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84 S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity Puthenveetil, Robbins

297 4 p.
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85 SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity Olia, Adam S.

297 4 p.
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86 Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β Nies, Sarah Helena

297 4 p.
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87 Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity Kim, Hyunsup

297 4 p.
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88 Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR Gubensäk, Nina

297 4 p.
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89 Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins Bowen, Nicole E.

297 4 p.
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90 Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1 Guo, Yusong

297 4 p.
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91 Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus Madland, Eva

297 4 p.
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92 Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection Dwivedi, Rohini

297 4 p.
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93 Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex Liu, Weifeng

297 4 p.
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94 Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets Chua, Sheena M.H.

297 4 p.
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95 Structural insights into the mechanism of pH-selective substrate specificity of the polysaccharide lyase Smlt1473 Pandey, Shubhant

297 4 p.
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96 Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis Carr, Samuel C.

297 4 p.
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97 Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide–catabolizing nitroreductase from Sphingopyxis sp. strain HMH Kim, Sang-Hoon

297 4 p.
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98 Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction Ahmad, Javeed

297 4 p.
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99 TBK1 has a new Akt Shaw, Leslie M.

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100 TFEB insufficiency promotes cardiac hypertrophy by blocking autophagic degradation of GATA4 Song, Rui

297 4 p.
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101 TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters Webb, Bryan M.

297 4 p.
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102 The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy Gandelman, Mandi

297 4 p.
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103 The circular RNA circBCL2L1 regulates innate immune responses via microRNA-mediated downregulation of TRAF6 in teleost fish Zheng, Weiwei

297 4 p.
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104 The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress Stromberg, Benjamin R.

297 4 p.
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105 The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium Tamura, Isao

297 4 p.
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106 The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions Gopalakrishnan, Rajaraman

297 4 p.
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107 The macromolecular complexes of histones affect protein arginine methyltransferase activities Fulton, Melody D.

297 4 p.
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108 The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation Yoast, Ryan E.

297 4 p.
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109 The periodic table of ribonucleotide reductases Ruskoski, Terry B.

297 4 p.
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110 The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene Mori, Kohji

297 4 p.
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111 The predicted stem-loop structure in the 3′-end of the human norovirus antigenomic sequence is required for its genomic RNA synthesis by its RdRp Shimoike, Takashi

297 4 p.
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112 The receptor-type protein tyrosine phosphatase CD45 promotes onset and severity of IL-1β–mediated autoinflammatory osteomyelitis Kralova, Jarmila

297 4 p.
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113 The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels Chen, Xu

297 4 p.
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114 The transcription factor Tfcp2l1 promotes primordial germ cell–like cell specification of pluripotent stem cells Zhang, Meng

297 4 p.
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115 The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids Frankovsky, Jan

297 4 p.
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116 Titratable transmembrane residues and a hydrophobic plug are essential for manganese import via the Bacillus anthracis ABC transporter MntBC-A Kuznetsova, Anastasiya

297 4 p.
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117 Topological analyses of the L-lysine exporter LysO reveal a critical role for a conserved pair of intramembrane solvent-exposed acidic residues Dubey, Swati

297 4 p.
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118 Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro Nguyen, Phong Quoc

297 4 p.
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119 Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid Zhao, Yang

297 4 p.
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120 USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates Zhang, Fengwu

297 4 p.
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121 Valproate activates the Snf1 kinase in Saccharomyces cerevisiae by decreasing the cytosolic pH Salsaa, Michael

297 4 p.
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122 Vitamin D signaling inhibits HBV activity by directly targeting the HBV core promoter Ahluwalia, Shivaksh

297 4 p.
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123 Working toward reducing bias in peer review Rye, Kerry-Anne

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                             123 results found
 
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