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                             59 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A Glutathione-independent Glyoxalase of the DJ-1 Superfamily Plays an Important Role in Managing Metabolically Generated Methylglyoxal in Candida albicans * * This work was supported, in whole or in part, by National Institutes of Health Grant R01 GM092999 (to M. A. W.). This work was also supported by Ann L. Kelsall and the Farnesol and Candida albicans Research Fund, University of Nebraska Foundation (to K. W. N.). Hasim, Sahar

289 3 p. 1662-1674
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2 A l-Lysine Transporter of High Stereoselectivity of the Amino Acid-Polyamine-Organocation (APC) Superfamily Kaur, Jagdeep

289 3 p. 1377-1387
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3 Androgen Receptor Splice Variant AR3 Promotes Prostate Cancer via Modulating Expression of Autocrine/Paracrine Factors* * This work was supported, in whole or in part, by National Institutes of Health Grant CA106504 (to Y. Q.). This work was also supported by Department of Defense Grant W81XWH-10-1-0309 (to Y. Q.). Sun, Feng

289 3 p. 1529-1539
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4 A Novel Cell Adhesion Region in Tropoelastin Mediates Attachment to Integrin αVβ5 * * This work was supported, in whole or in part, by National Institutes of Health Grant EB014283 (to A. S. W.). This work was also supported by the Australian Research Council, the Australian Defense Health Foundation, and the National Health and Medical Research Council (to A. S. W.) and by an Australian Postgraduate Research Award Ph.D. scholarship (to P. L.). A. S. W. is the scientific founder of Elastagen Pty. Ltd. Lee, Pearl

289 3 p. 1467-1477
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5 A Novel Mercuric Reductase from the Unique Deep Brine Environment of Atlantis II in the Red Sea This article contains supplemental Figs. 1–3, Tables 1 and 2, and additional references. Sayed, Ahmed

289 3 p. 1675-1687
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6 A Novel “Oxygen-induced” Greening Process in a Cyanobacterial Mutant Lacking the Transcriptional Activator ChlR Involved in Low-oxygen Adaptation of Tetrapyrrole Biosynthesis* * This work was supported by Grants-in-aid for Scientific Research 19570036, 20200063, and 23370020 (to Y. F.) and 12J00105 (to R. A.) and the Advanced Low Carbon Technology Research and Development Program (ALCA) of the Japan Science and Technology Agency. Aoki, Rina

289 3 p. 1841-1851
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7 Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro * * This work was supported, in whole or in part, by National Institutes of Health Grant NS059690. This article contains supplemental Figs. 1–3. Rauch, Jennifer N.

289 3 p. 1402-1414
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8 Biochemical and Structural Insights into RNA Binding by Ssh10b, a Member of the Highly Conserved Sac10b Protein Family in Archaea* * This work was supported by National Natural Science Foundation of China Grants 31130003 (to L. H.), 31000022 (to L. G.), and 31100535 (to J. D.); Chinese Ministry of Science and Technology 973 Program Grants 2011CB910304 and 2011CB911103 (to D.-C. W.); and Chinese Academy of Sciences Grant KSCX2-EW-J-3 (to D.-C. W.). Guo, Li

289 3 p. 1478-1490
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9 Brain-derived Neurotrophic Factor (BDNF)-induced Mitochondrial Motility Arrest and Presynaptic Docking Contribute to BDNF-enhanced Synaptic Transmission* * This work was supported by National 973 Basic Research Program of China Grant 2012CB911000, National Natural Science Foundation of China Grants 31130026 and 31100968, State Program of National Natural Science Foundation of China for Innovative Research Group Grant 81321061, China Postdoctoral Science Foundation Grants 20110491590 and 2012T50609, Specialized Research Fund for the Doctoral Program of Higher Education 20100131120052, and the Independent Innovation Foundation of Shandong University. ♦ Su, Bo

289 3 p. 1213-1226
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10 Brain-derived Neurotrophic Factor Controls Mitochondrial Transport in Neurons♦
289 3 p. 1227
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11 Characterization of a Stem-like Subpopulation in Basal-like Ductal Carcinoma in Situ (DCIS) Lesions* * This work was supported, in whole or in part, by grants from American Cancer Society and NCI, National Institutes of Health R01 CA163820 and R01 CA157779 (to Q. Z.). Li, Qinglin

289 3 p. 1303-1312
artikel
12 Characterization of Intermediate Steps in Amyloid Beta (Aβ) Production under Near-native Conditions* * This work was supported by grants from the Deutsche Forschungsgemeinschaft (DFG) (MU901; SFB740) and the Hans und Ilse Breuer foundation (to V. A.). Olsson, Fredrik

289 3 p. 1540-1550
artikel
13 Connexin43 Reduces Melanoma Growth within a Keratinocyte Microenvironment and during Tumorigenesis in Vivo * * This work was supported by funds from the Canadian Institutes of Health Research (to D. W. L.). Ableser, Mark J.

289 3 p. 1592-1603
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14 Cross-talk between Aryl Hydrocarbon Receptor and the Inflammatory Response Vogel, Christoph F.A.

289 3 p. 1866-1875
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15 Cuz1/Ynl155w, a Zinc-dependent Ubiquitin-binding Protein, Protects Cells from Metalloid-induced Proteotoxicity* * This work was supported by National Institutes of Health Grant GM043601 (to D. F.). Hanna, John

289 3 p. 1876-1885
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16 Designer Nodal/BMP2 Chimeras Mimic Nodal Signaling, Promote Chondrogenesis, and Reveal a BMP2-like Structure Esquivies, Luis

289 3 p. 1788-1797
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17 Dissociated GαGTP and Gβγ Protein Subunits Are the Major Activated Form of Heterotrimeric Gi/o Proteins* * This work was supported by European Commission FP7 Marie Curie International Reintegration Grant PIRG-GA-2007-209789 “MemSensors” (to J. L.), by Czech Government Institutional Grant AVOZ60870520 (to J. L.), by Grant P205/13-10799S (to J. L.), by University of South Bohemia Grant Agency Grant 141/2013/P (to A. B.), and by a University of South Bohemia fellowship (to A. B.). Patent 302233, covering the method of 2PPM, device and applications, has been awarded by the Industrial Property Office of the Czech Republic (to J. L.). A Patent Cooperation Treaty (PCT) application has been filed (by J. L.). J. L. is a founder and owner of Innovative Bioimaging, LLC. This article contains supplemental Figs. 1 and 2 and Methods. Bondar, Alexey

289 3 p. 1271-1281
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18 Editorial Board
289 3 p. i-iii
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19 Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor α El Hachmane, Mickael-F

289 3 p. 1388-1401
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20 Extracellular Calcium Modulates Actions of Orthosteric and Allosteric Ligands on Metabotropic Glutamate Receptor 1α* * This work was supported, in whole or in part, by National Institutes of Health Grants GM081749-01 (to J. J. Y.), DK078331 (to E. M. B.), and NS055179 (to R. A. H.). This work was also supported by a Brains and Behavior fellowship (to Y. J.). Jiang, Jason Y.

289 3 p. 1649-1661
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21 FGF16 Promotes Invasive Behavior of SKOV-3 Ovarian Cancer Cells through Activation of Mitogen-activated Protein Kinase (MAPK) Signaling Pathway* * This work was supported by Council of Scientific and Industrial Research projects BSC 0101 and BSC 0206, Government of India. Basu, Moitri

289 3 p. 1415-1428
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22 Functional Evaluation of Activation-dependent Alterations in the Sialoglycan Composition of T Cells* * This work was supported by grants-in-aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan; the Uehara Memorial Foundation; the Suzuken Memorial Foundation; and CREST, Japan Science and Technology Agency. Naito-Matsui, Yuko

289 3 p. 1564-1579
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23 Functional Properties of the Retinal Glutamate Transporters GLT-1c and EAAT5* * These studies were supported by the Deutsche Forschungs-gemeinschaft FA301/9 (to Ch. F.). Schneider, Nicole

289 3 p. 1815-1824
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24 Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress* * This work was supported by a grant-in-aid from the Heart and Stroke Foundation of Canada (to C. C. N.) and the Fondo Nacional de Desarrollo Científico y Tecnologico Grant FONDECYT 3120006 (to J. L. V.) of Chile. Funding was partly provided through the CIHR Team Grant on ”Vascular Cognitive Impairment: Animal Models of Co-morbidity.” Le, Hoa T.

289 3 p. 1345-1354
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25 Growth Arrest by the Antitumor Steroidal Lactone Withaferin A in Human Breast Cancer Cells Is Associated with Down-regulation and Covalent Binding at Cysteine 303 of β-Tubulin* * This work was supported, in whole or in part, by National Institutes of Health Grants R01 CA142604-04 and R01 CA129347-07 from NCI (to S. V. S.) and by the Intramural Research Program of the Center for Cancer Research, NCI, National Institutes of Health (to X. J.). The work performed in the University of Pittsburgh Cancer Institute Flow Cytometry Facility and Cancer Biomarkers Facility was supported in part by National Institutes of Health Cancer Center Support Grant P30CA047904 from NCI. Antony, Marie L.

289 3 p. 1852-1865
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26 Hyaluronic Acid Receptor for Endocytosis (HARE)-mediated Endocytosis of Hyaluronan, Heparin, Dermatan Sulfate, and Acetylated Low Density Lipoprotein (AcLDL), but Not Chondroitin Sulfate Types A, C, D, or E, Activates NF-κB-regulated Gene Expression* * This work was supported, in whole or in part, by National Institutes of Health Grant GM69961 from NIGMS. This work was also supported by Oklahoma Center for the Advancement of Science and Technology Grant HR10-074 from the State of Oklahoma. Pandey, Madhu S.

289 3 p. 1756-1767
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27 IκB Kinase γ/Nuclear Factor-κB-Essential Modulator (IKKγ/NEMO) Facilitates RhoA GTPase Activation, which, in Turn, Activates Rho-associated Kinase (ROCK) to Phosphorylate IKKβ in Response to Transforming Growth Factor (TGF)-β1* * This work was supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Education, the Ministry of Science, Information Communication Technology, and Future Planning (Grants NRF-2013R1A1A2A10006114 and MRC-2010-0009180) and Hallym University (Grant HRF-S-41). This article contains supplemental Fig. S1. Kim, Hee-Jun

289 3 p. 1429-1440
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28 Identification and Characterization of Functionally Critical, Conserved Motifs in the Internal Repeats and N-terminal Domain of Yeast Translation Initiation Factor 4B (yeIF4B)* * This work was supported, in whole or in part, by National Institutes of Health Intramural Research Program Grant (to A. G. H. and F. Z.) and Grant GM62128 (to J. R. L.). This work was also supported by an American Heart Association postdoctoral fellowship (to S. E. W.). Zhou, Fujun

289 3 p. 1704-1722
artikel
29 Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. Zhang, Sufang

289 3 p. 1212
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30 Index
289 3 p. iv-ix
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31 Leptin Signaling Is Required for Leucine Deprivation-enhanced Energy Expenditure* * This work was supported in part by the Ministry of Science and Technology of China 973 Program 2010CB912502 and 2009CB919001, National Natural Science Foundation Grants 81130076, 31271269, and 81100615, Key Program of Shanghai Scientific and Technological Innovation Action Plan Grant 13JC1409000, Knowledge Innovation Program of Chinese Academy of Sciences Grant KSCX2-EW-R-09, Chinese Academy of Sciences Project 2011KIP307. Zhang, Qian

289 3 p. 1779-1787
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32 Liver Kinase B1 Expression Promotes Phosphatase Activity and Abrogation of Receptor Tyrosine Kinase Phosphorylation in Human Cancer Cells* * This work was supported, in whole or in part, by National Institutes of Health Grants HL079584, HL080499, HL074399, HL089920, HL096032, HL105157, and HL110488 (to M.-H. Z.). Okon, Imoh S.

289 3 p. 1639-1648
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33 Matrilin-1 Is Essential for Zebrafish Development by Facilitating Collagen II Secretion* * This work was supported by Deutsche Forschungsgemeinschaft Grant WA1338/2-6 (to R. W. and M. P.). Neacsu, Cristian Dan

289 3 p. 1505-1518
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34 Mechanoregulation of h2-Calponin Gene Expression and the Role of Notch Signaling* * This work was supported, in whole or in part, by National Institutes of Health Grant HL-086720 (to J. P. J.). Jiang, Wen-rui

289 3 p. 1617-1628
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35 Mitochondria Contribute to NADPH Generation in Mouse Rod Photoreceptors* * This work was supported, in whole or in part, by National Institutes of Health Grant R01-EY014850. This work was also supported by an unrestricted grant to the Department of Ophthalmology at Medical University of South Carolina from Research to Prevent Blindness (New York). This work was conducted in a facility constructed with support from National Institutes of Health Grant C06 RR015455 from the Extramural Research Facilities Program of the National Center for Research Resources. Adler IV, Leopold

289 3 p. 1519-1528
artikel
36 Molecular and Thermodynamic Mechanisms of the Chloride-dependent Human Angiotensin-I-converting Enzyme (ACE)* * This work was supported by Medical Research Council Project Grant G1001685 and Wellcome Trust Equipment Grant 088464 (to K. R. A.). This work was also supported by the University of Cape Town and the South African National Research Foundation (to E. D. S. and C. J. Y.). Yates, Christopher J.

289 3 p. 1798-1814
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37 Neuroprotective Role of the Basic Leucine Zipper Transcription Factor NFIL3 in Models of Amyotrophic Lateral Sclerosis* * This work was supported in part by grants-in-aid from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (to N. K., Y. F., and K. S.) and by an operating grant from the Canadian Institutes of Health Research (to M. D. N). Tamai, So-ichi

289 3 p. 1629-1638
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38 Novel Mechanism of Positive versus Negative Regulation by Thyroid Hormone Receptor β1 (TRβ1) Identified by Genome-wide Profiling of Binding Sites in Mouse Liver* * This work was supported, in whole or in part, by National Institutes of Health Grants DK-091941 and DK-056123 (to A. N. H.). Ramadoss, Preeti

289 3 p. 1313-1328
artikel
39 Overlapping and Distinct Roles of Aspergillus fumigatus UDP-glucose 4-Epimerases in Galactose Metabolism and the Synthesis of Galactose-containing Cell Wall Polysaccharides* * This work was supported, in whole or in part, by National Institutes of Health Grant R01AI073829. This work was also supported by operating funds from the Canadian Institutes of Health Research. Lee, Mark J.

289 3 p. 1243-1256
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40 Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytes* * This work was supported by British Heart Foundation (BHF) 4-year Ph.D. Program FS/06/079, Centre of Research Excellence Award RE/08/003, and Medical Research Council Grant G0800206. This article contains supplemental Figs. S1–S5, Experimental Procedures, and references. Candasamy, Alexandra J.

289 3 p. 1282-1293
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41 Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA* * This work was supported, in whole or in part, by National Institutes of Health Grants R01 GM098624 (to D. C. W.) and R01 DK029902 (to G. D. G.). NMR data were acquired using NMR instrumentation in the Virginia Commonwealth University Massey Cancer Center Structural Biology Core, and surface plasmon resonance data were acquired in the Virginia Commonwealth University Massey Cancer Center Flow Cytometry Core, both of which are supported, in part, by NCI Cancer Center Core Support Grant P30 CA016059. Cramer, Jason M.

289 3 p. 1294-1302
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42 Proteome Analysis and Conditional Deletion of the EAAT2 Glutamate Transporter Provide Evidence against a Role of EAAT2 in Pancreatic Insulin Secretion in Mice* * This work was supported by the Norwegian Research Council (Centre of Excellence, Centre for Molecular Biology and Neuroscience, and Grants 164297-V40 and 183727-S10) and by the Norwegian Advanced Research Program (Toppforskningsprogrammet). This article contains supplemental Tables S1 and S2. Zhou, Yun

289 3 p. 1329-1344
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43 Regulated Assembly of Vacuolar ATPase Is Increased during Cluster Disruption-induced Maturation of Dendritic Cells through a Phosphatidylinositol 3-Kinase/mTOR-dependent Pathway* * This work was supported, in whole or in part, by National Institutes of Health Grants GM34478 (to M. F.) and NIAID RO1 18919 (to M. J. S.). This work was also supported by a Sackler Dean's Fellow award (to R. L.). Liberman, Rachel

289 3 p. 1355-1363
artikel
44 Regulation of Mitochondrial Antiviral Signaling (MAVS) Expression and Signaling by the Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Protein Gp78* * This work was supported, in whole or in part, by National Institutes of Health Grant R01-AI081759 (to C. B. C.). Jacobs, Jana L.

289 3 p. 1604-1616
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45 Regulation of Protease-activated Receptor 1 Signaling by the Adaptor Protein Complex 2 and R4 Subfamily of Regulator of G Protein Signaling Proteins* * This work was supported, in whole or in part, by National Institutes of Health Grant R01 GM090689 (to J. T.). Chen, Buxin

289 3 p. 1580-1591
artikel
46 Serine Hydrolase Inhibitors Block Necrotic Cell Death by Preventing Calcium Overload of the Mitochondria and Permeability Transition Pore Formation* * This work was supported, in whole or in part, by National Institutes of Health Grants HL61378, HL34303, HL50040, DA009789, DA033760, and MH084512 and a Hewitt Foundation Postdoctoral Fellowship. Yun, Bogeon

289 3 p. 1491-1504
artikel
47 Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor VIIa by Tissue Factor Pathway Inhibitor (TFPI)* * M. D., R. H., M. F., and F. S. are full time employees of Baxter Innovations GmbH; F. O., T. P., and U. R. are full time employees of 3B Pharmaceuticals, GmbH; and J. R. is a consultant of Baxter Innovations GmbH. This article contains supplemental Tables S1 and S2 and Fig. S1. Dockal, Michael

289 3 p. 1732-1741
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48 Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix* * This work was supported in part by Canadian Institutes of Health Research Grants MT-12134 (to R. B. C.) and MOP-62690 (to D. P. T.). Lee, Jaeyong

289 3 p. 1742-1755
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49 Structural Basis of Biological NO Generation by Octaheme Oxidoreductases* * This work was supported by Netherlands Organization for Scientific Research Darwin Grants 142.16.1201 (to W. J. M.) and VENI 863.11.003 (to B. K.), by European Research Council Advanced Grant 232937 (to M. S. M. J), by the Max-Planck Society, and by UK Biotechnology and Biological Sciences Research Council Grant BB/G009228 (to S. J. M.). This article contains supplemental Fig. S1. Maalcke, Wouter J.

289 3 p. 1228-1242
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50 Sympathetic Activation Induces Skeletal Fgf23 Expression in a Circadian Rhythm-dependent Manner* * This work was supported by a grant from Sukoyaka Grant for Maternal and Child Health (to M. K.). This article contains supplemental Figs. S1 and S2. Kawai, Masanobu

289 3 p. 1457-1466
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51 The A2A Adenosine Receptor Is a Dual Coding Gene Lee, Chien-fei

289 3 p. 1257-1270
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52 The Diarylheptanoid Hirsutenone Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin via Modulation of Apoptosis-inducing Factor and X-linked Inhibitor of Apoptosis* * This work was supported by grants from the World Class University (WCU) program R31-10056 through the National Research Foundation of Korea, funded by the Ministry of Education, Science, and Technology, and by Canadian Institutes of Health Research Grant M0P-126144. Farrand, Lee

289 3 p. 1723-1731
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53 The MF6p/FhHDM-1 Major Antigen Secreted by the Trematode Parasite Fasciola hepatica Is a Heme-binding Protein* * This work was supported in part by Ministerio de Ciencia e Innovación, Spain, Grants AGL2010-22290-C02 and AGL2011-30563-C03; Xunta de Galicia, Spain, Grant CN 2012/155; and the European Fund for Regional Development (FEDER). Martínez-Sernández, Victoria

289 3 p. 1441-1456
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54 The Role of Diacylglycerol Kinase ζ and Phosphatidic Acid in the Mechanical Activation of Mammalian Target of Rapamycin (mTOR) Signaling and Skeletal Muscle Hypertrophy* * This work was supported, in whole or in part, by National Institutes of Health Grant AR057347 (to T. A. H.). You, Jae-Sung

289 3 p. 1551-1563
artikel
55 The Small GTPase Arf6 Is Essential for the Tram/Trif Pathway in TLR4 Signaling* * This research was supported using grants from Ghent University (Group-ID Multidisciplinary Research Partnerships) and the Belgian Government (Interuniversitary Attraction Poles P7/13). This article contains supplemental Table S1. Van Acker, Tim

289 3 p. 1364-1376
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56 The Two Na+ Sites in the Human Serotonin Transporter Play Distinct Roles in the Ion Coupling and Electrogenicity of Transport* * This work was supported, in whole or in part, by National Institutes of Health K01 Career Development Award DA022378 (to L. K. H.) and by National Institutes of Health, NIGMS, Institutional Development Award (IDeA) P20GM12345. This work was also supported by a National Science Foundation-EPSCoR Faculty Startup Award (to L. K. H.) and Austrian Science Foundation/FWF Grant F3506 (to H. H. S.). This article contains supplemental Fig. S1. Felts, Bruce

289 3 p. 1825-1840
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57 Unfolded Protein Response Signaling and Metabolic Diseases* * This work was supported, in whole or in part, by National Institutes of Health Grants R01 DK081009 and R01 DK098496 (to U. O.). This work was also supported by American Diabetes Association Career Development Grant 7-09-CD-10 (to U. O.). Lee, Jaemin

289 3 p. 1203-1211
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58 Unremodeled and Remodeled Cardiolipin Are Functionally Indistinguishable in Yeast* * This work was supported, in whole or in part, by National Institutes of Health Grants R00HL089185 and 1R01HL108882 (to S. M. C.) and Grant SRR022588A from NCRR (to J. M. M.). This work was also supported by National Science Foundation Grant MCB-1024908 (to N. N. A.) and intramural institutional research funds (to X. H.). This article contains supplemental Table 1. Baile, Matthew G.

289 3 p. 1768-1778
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59 Very Low Density Lipoprotein Receptor (VLDLR) Expression Is a Determinant Factor in Adipose Tissue Inflammation and Adipocyte-Macrophage Interaction* * This work was supported by development grants from Hackensack University Medical Center and American Heart Association Award AHA0730356N. Nguyen, Andrew

289 3 p. 1688-1703
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                             59 gevonden resultaten
 
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