| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A BAF’ling Approach to Curing HIV
|
Tomar, Sakshi
|
|
2018
|
|
12 |
p. 1441-1442
|
artikel
|
| 2 |
(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition
|
Rack, Johannes Gregor Matthias
|
|
2018
|
|
12 |
p. 1533-1546.e12
|
artikel
|
| 3 |
A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization
|
Kim, Hyaeyeong
|
|
|
|
12 |
p. 1725-1731.e6
|
artikel
|
| 4 |
A game of networks: Do different lipids interact to orchestrate inflammatory homeostasis?
|
Leuti, Alessandro
|
|
|
|
12 |
p. 1499-1501
|
artikel
|
| 5 |
AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms
|
Castillo Cabrera, Johnny
|
|
|
|
12 |
p. 1601-1616.e6
|
artikel
|
| 6 |
A Highly Efficient CRISPR-Cas9-Based Genome Engineering Platform in Acinetobacter baumannii to Understand the H2O2-Sensing Mechanism of OxyR
|
Wang, Yu
|
|
|
|
12 |
p. 1732-1742.e5
|
artikel
|
| 7 |
A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli
|
Des Soye, Benjamin J.
|
|
|
|
12 |
p. 1743-1754.e9
|
artikel
|
| 8 |
A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells
|
Peterson, Jackson J.
|
|
|
|
12 |
p. 1617-1633.e9
|
artikel
|
| 9 |
ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells
|
Sarvi, Sana
|
|
2018
|
|
12 |
p. 1456-1469.e6
|
artikel
|
| 10 |
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
|
Arnold, Moriah R.
|
|
|
|
12 |
p. 1694-1708.e10
|
artikel
|
| 11 |
A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis
|
Rittershaus, Emily S.C.
|
|
2018
|
|
12 |
p. 1495-1505.e3
|
artikel
|
| 12 |
A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis
|
Hu, Huabin
|
|
|
|
12 |
p. 1634-1651.e6
|
artikel
|
| 13 |
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening
|
Rich, Michelle H.
|
|
|
|
12 |
p. 1680-1691.e6
|
artikel
|
| 14 |
A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form
|
Miyamae, Yusaku
|
|
|
|
12 |
p. 1573-1581.e3
|
artikel
|
| 15 |
Ammosamides Unveil Novel Biosynthetic Machinery
|
Colosimo, Dominic A.
|
|
2016
|
|
12 |
p. 1444-1446
3 p.
|
artikel
|
| 16 |
An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3
|
Kizuka, Yasuhiko
|
|
2017
|
|
12 |
p. 1467-1478.e5
|
artikel
|
| 17 |
An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor
|
Zaidman, Daniel
|
|
|
|
12 |
p. 1795-1806.e5
|
artikel
|
| 18 |
An Axonal Blueprint: Generating Neuronal Polarity with Light-Inducible Proteins
|
Lin, Michael Z.
|
|
|
|
12 |
p. 1634-1636
|
artikel
|
| 19 |
An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway
|
Bose, Debojit
|
|
2016
|
|
12 |
p. 1539-1549
11 p.
|
artikel
|
| 20 |
A photocaged orexin-B for spatiotemporally precise control of orexin signaling
|
Duffet, Loïc
|
|
|
|
12 |
p. 1729-1738.e8
|
artikel
|
| 21 |
A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity
|
Kirby, Ilsa T.
|
|
2018
|
|
12 |
p. 1547-1553.e12
|
artikel
|
| 22 |
A Rhomboid in the Rough: Potent Inhibitors for a Previously Undruggable Target
|
Moskal, Natalia
|
|
2017
|
|
12 |
p. 1431-1433
|
artikel
|
| 23 |
Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria
|
Labana, Puneet
|
|
|
|
12 |
p. 1703-1715.e11
|
artikel
|
| 24 |
A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling
|
Revankar, Chetana M.
|
|
|
|
12 |
p. 1692-1702.e5
|
artikel
|
| 25 |
A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth
|
Goh, Eddy T.H.
|
|
2018
|
|
12 |
p. 1485-1494.e5
|
artikel
|
| 26 |
A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions
|
Claes, Zander
|
|
|
|
12 |
p. 1666-1679.e6
|
artikel
|
| 27 |
Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
|
Zhang, Jing
|
|
|
|
12 |
p. 1500-1509.e13
|
artikel
|
| 28 |
A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death
|
Ko, Pin-Joe
|
|
|
|
12 |
p. 1716-1724.e9
|
artikel
|
| 29 |
Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes
|
Finan, Gina M.
|
|
2016
|
|
12 |
p. 1526-1538
13 p.
|
artikel
|
| 30 |
Biosynthetic Pathway Connects Cryptic Ribosomally Synthesized Posttranslationally Modified Peptide Genes with Pyrroloquinoline Alkaloids
|
Jordan, Peter A.
|
|
2016
|
|
12 |
p. 1504-1514
11 p.
|
artikel
|
| 31 |
Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
|
Pearah, Alexia
|
|
|
|
12 |
p. 1585-1600.e6
|
artikel
|
| 32 |
B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro
|
Gale, Robert T.
|
|
2017
|
|
12 |
p. 1537-1546.e4
|
artikel
|
| 33 |
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators
|
Peltner, Lukas K.
|
|
|
|
12 |
p. 1508-1524.e7
|
artikel
|
| 34 |
Chemoproteomic strategy identified p120-catenin glutathionylation regulates E-cadherin degradation and cell migration
|
Kukulage, Dhanushika S.K.
|
|
|
|
12 |
p. 1542-1556.e9
|
artikel
|
| 35 |
Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis
|
Schneidewind, Tabea
|
|
|
|
12 |
p. 1780-1794.e5
|
artikel
|
| 36 |
Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells
|
Kimura, Azuma
|
|
|
|
12 |
p. 1561-1572.e7
|
artikel
|
| 37 |
D Amino Acids Highlight the Catalytic Power of the Ribosome
|
Lehmann, Jean
|
|
|
|
12 |
p. 1639-1641
|
artikel
|
| 38 |
Death by Retrograde Transport: Avoiding the Apoptosis Default
|
Green, Douglas R.
|
|
|
|
12 |
p. 1636-1638
|
artikel
|
| 39 |
Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation
|
Araki, Shinsuke
|
|
2018
|
|
12 |
p. 1470-1484.e5
|
artikel
|
| 40 |
Development of an intracellular quantitative assay to measure compound binding kinetics
|
Lay, Charles S.
|
|
|
|
12 |
p. 1692
|
artikel
|
| 41 |
Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents
|
Bos, Pieter H.
|
|
|
|
12 |
p. 1703-1715.e37
|
artikel
|
| 42 |
Development of potent dimeric inhibitors of GAS41 YEATS domain
|
Listunov, Dymytrii
|
|
|
|
12 |
p. 1716-1727.e6
|
artikel
|
| 43 |
Discovery of an Inhibitor for Bacterial 3-Mercaptopyruvate Sulfurtransferase that Synergistically Controls Bacterial Survival
|
Croppi, Giorgia
|
|
|
|
12 |
p. 1483-1499.e9
|
artikel
|
| 44 |
Discovery of Covalent MKK4/7 Dual Inhibitor
|
Jiang, Jie
|
|
|
|
12 |
p. 1553-1560.e8
|
artikel
|
| 45 |
Dissonance Strikes a Chord in Stilbene Synthesizers
|
Holland, Cynthia K.
|
|
2016
|
|
12 |
p. 1440-1441
2 p.
|
artikel
|
| 46 |
Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved
|
Hine, Christopher
|
|
|
|
12 |
p. 1665-1668
|
artikel
|
| 47 |
Eradicating Bacterial Persisters with Combinations of Strongly and Weakly Metabolism-Dependent Antibiotics
|
Zheng, Erica J.
|
|
|
|
12 |
p. 1544-1552.e3
|
artikel
|
| 48 |
Exploiting polypharmacology to dissect host kinases and kinase inhibitors that modulate endothelial barrier integrity
|
Dankwa, Selasi
|
|
|
|
12 |
p. 1679-1692.e4
|
artikel
|
| 49 |
Fluorescent Visualization of Cellular Proton Fluxes
|
Zhang, Lejie
|
|
2016
|
|
12 |
p. 1449-1457
9 p.
|
artikel
|
| 50 |
Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin
|
Xia, Yongliang
|
|
2017
|
|
12 |
p. 1479-1489.e4
|
artikel
|
| 51 |
General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases
|
Tichá, Anežka
|
|
2017
|
|
12 |
p. 1523-1536.e4
|
artikel
|
| 52 |
Generation of Fluorinated Amychelin Siderophores against Pseudomonas aeruginosa Infections by a Combination of Genome Mining and Mutasynthesis
|
Xie, Feng
|
|
|
|
12 |
p. 1532-1543.e6
|
artikel
|
| 53 |
Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation
|
Ciancone, Anthony M.
|
|
|
|
12 |
p. 1709-1720.e7
|
artikel
|
| 54 |
Glycan Microarray Reveal the Sweet Side of Cancer Vaccines
|
Padler-Karavani, Vered
|
|
2016
|
|
12 |
p. 1446-1447
2 p.
|
artikel
|
| 55 |
G-quadruplexes Sequester Free Heme in Living Cells
|
Gray, Lucas T.
|
|
|
|
12 |
p. 1681-1691.e5
|
artikel
|
| 56 |
High-Content Imaging Platform for Profiling Intracellular Signaling Network Activity in Living Cells
|
Kuchenov, Dmitry
|
|
2016
|
|
12 |
p. 1550-1559
10 p.
|
artikel
|
| 57 |
Hydropersulfides are endogenous antioxidants that inhibit ferroptosis
|
Lange, Mike
|
|
|
|
12 |
p. 1661-1663
|
artikel
|
| 58 |
Identification and validation of selective deubiquitinase inhibitors
|
Varca, Anthony C.
|
|
|
|
12 |
p. 1758-1771.e13
|
artikel
|
| 59 |
Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
|
Kwak, Chulhwan
|
|
|
|
12 |
p. 1739-1753.e6
|
artikel
|
| 60 |
Identification of Small-Molecule Activators of the Ubiquitin Ligase E6AP/UBE3A and Angelman Syndrome-Derived E6AP/UBE3A Variants
|
Offensperger, Fabian
|
|
|
|
12 |
p. 1510-1520.e6
|
artikel
|
| 61 |
Identifying Anti-prion Chemical Compounds Using a Newly Established Yeast High-Throughput Screening System
|
Du, Zhiqiang
|
|
|
|
12 |
p. 1664-1680.e4
|
artikel
|
| 62 |
Imaging-Based Screening Platform Assists Protein Engineering
|
Fabritius, Arne
|
|
2018
|
|
12 |
p. 1554-1561.e8
|
artikel
|
| 63 |
In This Issue
|
|
|
2016
|
|
12 |
p. v-vi
nvt p.
|
artikel
|
| 64 |
Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage
|
Jiang, Xiaofeng
|
|
|
|
12 |
p. 1669-1678.e5
|
artikel
|
| 65 |
Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
|
Sobinoff, Alexander P.
|
|
|
|
12 |
p. 1652-1665.e6
|
artikel
|
| 66 |
Knocking off cancer’s HAT: CSS1477 disrupts oncogenic programs
|
Xu, Luyao Kevin
|
|
|
|
12 |
p. 1505-1507
|
artikel
|
| 67 |
Locally Activating TrkB Receptor Generates Actin Waves and Specifies Axonal Fate
|
Woo, Doyeon
|
|
|
|
12 |
p. 1652-1663.e4
|
artikel
|
| 68 |
Mapping the residue specificities of epigenome enzymes by yeast surface display
|
Waldman, Alison C.
|
|
|
|
12 |
p. 1772-1779.e4
|
artikel
|
| 69 |
Mechanism-Based Personalized Medicine for Cystic Fibrosis by Suppressing Pseudo Exon Inclusion
|
Shibata, Saiko
|
|
|
|
12 |
p. 1472-1482.e6
|
artikel
|
| 70 |
Metabolic modulation of transcription: The role of one-carbon metabolism
|
Lin, Jung-Ming G.
|
|
|
|
12 |
p. 1664-1679
|
artikel
|
| 71 |
Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate
|
Drown, Bryon S.
|
|
2018
|
|
12 |
p. 1562-1570.e19
|
artikel
|
| 72 |
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates
|
Reeve, Stephanie M.
|
|
2016
|
|
12 |
p. 1458-1467
10 p.
|
artikel
|
| 73 |
Multi-targeting Drug Community Challenge
|
Schlessinger, Avner
|
|
2017
|
|
12 |
p. 1434-1435
|
artikel
|
| 74 |
5-Nitrofurans and Cancer: Teaching an Old Drug New Tricks
|
Peterson, Randall T.
|
|
2018
|
|
12 |
p. 1439-1440
|
artikel
|
| 75 |
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation
|
Muneer, Adil
|
|
|
|
12 |
p. 1525-1541.e7
|
artikel
|
| 76 |
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
|
Zhang, Si Min
|
|
|
|
12 |
p. 1693-1702.e6
|
artikel
|
| 77 |
PARP Inhibitors: Staying on Target?
|
Doig, Craig L.
|
|
2016
|
|
12 |
p. 1442-1443
2 p.
|
artikel
|
| 78 |
Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells
|
Perea, Valerie
|
|
|
|
12 |
p. 1571-1584.e5
|
artikel
|
| 79 |
Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets
|
Knezevic, Claire E.
|
|
2016
|
|
12 |
p. 1490-1503
14 p.
|
artikel
|
| 80 |
Quantitative Imaging of Labile Zn2+ in the Golgi Apparatus Using a Localizable Small-Molecule Fluorescent Probe
|
Kowada, Toshiyuki
|
|
|
|
12 |
p. 1521-1531.e8
|
artikel
|
| 81 |
Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States
|
Gentile, Daniel R.
|
|
2017
|
|
12 |
p. 1455-1466.e14
|
artikel
|
| 82 |
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice
|
Apostolos, Alexis J.
|
|
|
|
12 |
p. 1721-1728.e5
|
artikel
|
| 83 |
Responsive Antibody Conjugates Enable Quantitative Determination of Intracellular Bond Degradation Rate
|
Sorkin, Michelle R.
|
|
|
|
12 |
p. 1643-1651.e4
|
artikel
|
| 84 |
Serotonin is a common thread linking different classes of antidepressants
|
Witt, Colby E.
|
|
|
|
12 |
p. 1557-1570.e6
|
artikel
|
| 85 |
Severing Ties: Quantifying the Payload Release from Antibody Drug Conjugates
|
Kopp, Anna
|
|
|
|
12 |
p. 1631-1633
|
artikel
|
| 86 |
Small-molecule allosteric inhibitors of GPX4
|
Liu, Hengrui
|
|
|
|
12 |
p. 1680-1693.e9
|
artikel
|
| 87 |
Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal
|
Marian, Christine A.
|
|
2018
|
|
12 |
p. 1443-1455.e14
|
artikel
|
| 88 |
Structural and mechanistic investigations of protein S-glycosyltransferases
|
Fujinami, Daisuke
|
|
|
|
12 |
p. 1740-1749.e6
|
artikel
|
| 89 |
Structural Insight into the Enzymatic Formation of Bacterial Stilbene
|
Mori, Takahiro
|
|
2016
|
|
12 |
p. 1468-1479
12 p.
|
artikel
|
| 90 |
Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7
|
Lamberto, Ilaria
|
|
2017
|
|
12 |
p. 1490-1500.e11
|
artikel
|
| 91 |
Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis
|
Wu, Yihan
|
|
2017
|
|
12 |
p. 1437-1444.e3
|
artikel
|
| 92 |
Synthetic Three-Component HIV-1 V3 Glycopeptide Immunogens Induce Glycan-Dependent Antibody Responses
|
Cai, Hui
|
|
2017
|
|
12 |
p. 1513-1522.e4
|
artikel
|
| 93 |
Tag, you’re it: G-ICAT identifies p120-cysteine glutathionylation triggering E-cadherin destabilization
|
Fridianto, Kevin T.
|
|
|
|
12 |
p. 1501-1504
|
artikel
|
| 94 |
Targeting Mammalian Translational Inhibition with Tetracyclines
|
Boer, Robert E.
|
|
2018
|
|
12 |
p. 1437-1438
|
artikel
|
| 95 |
Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment
|
Sanchez-Martin, Victoria
|
|
|
|
12 |
p. 1807
|
artikel
|
| 96 |
Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
|
Mortison, Jonathan D.
|
|
2018
|
|
12 |
p. 1506-1518.e13
|
artikel
|
| 97 |
That’s a Wrap!
|
Kostic, Milka
|
|
2016
|
|
12 |
p. 1439-
1 p.
|
artikel
|
| 98 |
The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition
|
Desroses, Matthieu
|
|
2017
|
|
12 |
p. 1429-1431
|
artikel
|
| 99 |
Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin
|
Carnero Corrales, Marjorie A.
|
|
|
|
12 |
p. 1750-1757.e5
|
artikel
|
| 100 |
The role of SERPIN citrullination in thrombosis
|
Tilvawala, Ronak
|
|
|
|
12 |
p. 1728-1739.e5
|
artikel
|
| 101 |
Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion
|
Wang, Shuen-Shiuan
|
|
2018
|
|
12 |
p. 1519-1532.e5
|
artikel
|
| 102 |
To Splice or Not to Splice, That Is the Treatment
|
Garcia-Blanco, Mariano A.
|
|
|
|
12 |
p. 1453-1455
|
artikel
|
| 103 |
Unsaturated Fatty Acid Synthesis in the Gastric Pathogen Helicobacter pylori Proceeds via a Backtracking Mechanism
|
Bi, Hongkai
|
|
2016
|
|
12 |
p. 1480-1489
10 p.
|
artikel
|
| 104 |
Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases
|
Maher, Pamela
|
|
|
|
12 |
p. 1456-1471
|
artikel
|
| 105 |
USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms
|
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