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1 Abstracts of the ECTS 2022 Hybrid Congress
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2 Activated Gs⍺ pathway and estrogens reveal different subsets of adiponectin-expressing osteoprogenitors within bone marrow stroma Palmisano, Biagio

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3 Adherence and barriers to the vitamin D and calcium supplement recommendation at Danish nursing homes: A cross-sectional study Mortensen, Charlotte

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4 β2-adrenoceptor-deficient mice exhibit exacerbated subchondral bone remodeling in experimental osteoarthritis Rösch, Gundula

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5 Age- and sex-specific risk of incident vertebral fractures for subsequent vertebral fractures: results from a large German health insurance dataset Glüer, Claus-Christian

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6 Age-progressive and gender-dependent bone phenotype in mice lacking both Ebf1 and Ebf2 in Prrx1-expressing mesenchymal cells Nieminen-Pihala, Vappu

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7 Age-related changes in osteocytes and blood vessels in the compact bone of the femur in mouse Palmier, Mathilde

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8 Age-related vertebral bone morphology and mineralization in the annual killifish – the shortest-lived vertebrate model Fiedler, Imke A.K.

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9 Agreement between Ireland DXA FRAX® and Web FRAX®: Preliminary Results of the DXA-HIP Study Yang, Lan

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10 A human cell-based in vitro model of bone for defining the dormant niche components for disseminated breast and prostate cancer cells Gebraad, Arjen

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11 Alendronate delays activation of bone formation in cortical bone in postmenopausal osteoporosis Borggaard, Xenia

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12 Altered glucose and glutamine metabolism drives chondrocytes dysfunction in osteoarthritis Stegen, Steve

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13 A mixed pattern of osteolytic and sclerotic lesions is characteristic in metastatic breast cancer patients as evidenced by histomorphometry Uguz, Melisa K.

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14 Anabolic effects of rhPTH and novel PTH analog on titanium osseointegration and bone regeneration in ovariectomized beagle model Lee, Jongbin

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15 Analysis of the transcriptome in the TgRANKL mouse model of osteoporosis reveals mRNAs, miRNAs, and lncRNAs as potent regulators of osteoporosis Ioannidou, Elisavet

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16 An in vitro 3D self-structuring bone model capable of long-term osteocyte culture Finlay, Melissa

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17 A novel smurf1 inhibitor-loaded alginate hydrogel for promoting local bone formation in distinctive age-related osteoporosis during spinal fusion Zhong, Chuanxin

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18 An unusual osteoporotic vertebral fracture – Kummell´s Disease Vilas-Boas, Joao

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19 Apparent calcium absorption of a novel calcium supplement – The RENEW study Rasmussen, Sidse Ida

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20 Application of machine learning for the semantic segmentation and morphological analysis of osteocyte processes and canaliculi Tabata, Kaori

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21 A predictive human 3D cartilage-on-chip model for screening anti-osteoarthritis drugs and medical devices Occhetta, Paola

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22 Are We Missing Vertebral Fragility Fractures In Patients Who Suffered A Hip Fracture? Genrinho, Inês

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23 Assessing inflammatory-circulating proteomics as potential biomarkers for sarcopenia-traits in middle-aged and older people: a population-based study Benz, Elizabeth

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24 Assessing pain in a mouse model of osteoporosis Radulescu, Andreea

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25 Assessment of the effect of Tofacitinib on bone marrow adipocytes and bone-forming osteoblasts under non-inflammatory and inflammatory conditions Letarouilly, Jean-Guillaume

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26 Association between exposure to fine particulate matter and osteoporosis: a population-based cohort study Adami, Giovanni

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27 Association between long-term exposure to air pollution and immune-mediated diseases: a population-based cohort study Adami, Giovanni

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28 Association between short-term exposure to environmental air pollution and psoriasis flare Adami, Giovanni

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29 Association of the vitamin D and parathyroid hormone status with the ageing-related decline of bone microarchitecture in older men – the prospective STRAMBO study Szulc, Pawel

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30 Atherothrombotic profile in subjects with parathyroid disorders: cross-sectional study Naciu, Anda Mihaela

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31 A two-year longitudinal study: Bone Loss in Patients with Erosive and Non-erosive Hand Osteoarthritis, Comparison Růžičková, Olga

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32 Atypical Femoral Shaft Fractures secondary to long-term Bisphosphonate therapy Cardoso, Rui

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33 Beneficial effect of denosumab on muscle performance in patients with low BMD: A retrospective, propensity score-matched analysis Rupp, Tobias

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34 Bioactive implant materials have distinct effects on osteoblastic cell migration Kajander, Karoliina

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35 Bioresorbable Magnesium Implants for first in Human surgical fixation of Ankle Fractures: Clinical follow-up and HR-pQCT Assessment of the Implantation Site Foessl, Ines

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36 B-lymphocytes influence postmenopausal bone loss in an HIF-1a dependent signaling Meng, Xianyi

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37 Bmp2 overexpression effects over appendicular skeleton development Muiños-López, Emma

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38 Bone complications in type 2 diabetes are mediated through differential genetic risks for insulin resistance or obesity Ghatan, Samuel

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39 Bone endocrine factor – Osteocalcin, Advanced glycation end products and type 2 diabetes mellitus – a low-profile step in the pathophysiology Waqas, Komal

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40 Bone impairment in a large cohort of Chinese patients with tumor-induced osteomalacia assessed by HR-pQCT and TBS Ni, Xiaolin

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41 Bone manifestations in systemic mastocytosis and related risk factors Ávalos, Hugo

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42 Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women: The case-control ADIMOS study Paccou, Julien

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43 Bone microstructure evaluated by TBS and HR-pQCT in Chinese adults with X-linked hypophosphatemia Ni, Xiaolin

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44 Bone morphogenetic protein 3 in bone tissue formation and regeneration Rumenovic, Viktorija

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45 Bone properties in a rat model of differential expression of the inflammatory Ciita gene Jensen, Vivi

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46 Bone quality in ovariectomized monkeys treated with two doses of teriparatide for either 18 months, or 12 months followed by withdrawal for 6 months Paschalis, Eleftherios

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47 Bone quality of growing rats submitted to food restriction and further refeeding: a histomorphometric and densitometric study Guedes, Patrícia

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48 Bone resorptive activity of human osteoclasts is altered on bone from Osteogenesis Imperfecta patients and mouse models in vitro Folkestad, Lars

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49 Bone tissue evaluation indicates abnormal mineralization in patients with autoimmune polyendocrine syndrome type I Laakso, Saila

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50 Breast cancer-induced changes of bone matrix quality is a consequence of mineral particle organization at hijacked remodelling sites Krug, Johannes

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51 Burden and cost of incident osteoporosis-related fractures in postmenopausal women Barcelos, Anabela

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52 BYL-719 administration prevents heterotopic ossification in FOP mice irrespective of ACVR1/ALK2 kinase activity Wits, Marius

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53 Calciphylaxis is Associated with Pyrophosphate Deficiency in Dialysis Patient's Exploratory Study Nigwekar, Sagar

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54 Cdk5 ablation in osteoblast lineage increases osteocyte apoptosis in mice Ahmad, Mubashir

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55 Changes in Circulating miRNAs in Postmenopausal Women with Osteoporosis during a 2-year Denosumab Treatment Schedule Messner, Zora

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56 Changes in RANKL and TRAcP 5b after discontinuation of denosumab suggest RANKL mediated recruitment of osteoclasts Sølling, Anne Sophie

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57 Characterization of lower limb deformities in children and adolescents with XLH Raimann, Adalbert

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58 Characterization of tissue-specific subchondral quality in hip osteoarthritis reveals stage- and region-dependent nanomechanical interface disruption Stürznickel, Julian

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59 Characterizing the bone phenotype of a polygenic mouse model of type 2 diabetes Emini, Lejla

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60 Chemotherapy-induced senescence promotes osteoclastogenesis and bone loss by triggering inflammatory responses in vivo Pimenta-Lopes, Carolina

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61 Chronic psychosocial stress disturbs endochondral ossification during bone growth and fracture healing via catecholamines locally produced by myeloid cells Tschaffon, Miriam

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62 Clawing our way forward in type 1 diabetes Patra, Shinjan

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63 Clinical and instrumental characteristics of the musculoskeletal system in young persons with joint hypermobility Akhiiarova, Karina

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64 Clinical, Biochemical, Radiological, Genetic and Therapeutic Analysis of Patients with COMP Gene Variants Liang, Hanting

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65 Clinical findings of the temporomandibular joint in 21 patients with Cartilage-hair hypoplasia and 42 controls Arponen, Heidi

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66 Cold exposure has a negative impact on bone mass in vivo Behler-Janbeck, Friederike

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67 Collagen X biomarker, linear growth and bone development in a Vitamin D intervention study in Infants Hauta-Alus, Helena

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68 Comparison of efficacy of rhBMP2 and rhBMP6 delivered within autologous blood coagulum with synthetic ceramics in rat subcutaneous assay Ivanjko, Natalia

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69 Comparison of Peripheral Nerve Block and Spinal Anesthesia in Terms of Postoperative Mortality and Walking Ability in Elderly Hip Fracture Patients Fu, Guangtao

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70 Comparison of the microarchitecture of commonly fractured vertebral bodies in the young and old Schober, Hans-Christof

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71 Competitive Blocking of LRP4-Sclerostin Binding Interface Strongly Promotes Bone Anabolic Functions Katchkovsky, Svetlana

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72 Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis during ovariectomy-induced bone loss in mice Wehrstein, Jasmin

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73 Compression Fractures and Partial Phenotype Rescue with a Low Phosphorus Diet in the Chihuahua Zebrafish Osteogenesis Imperfecta Model Cotti, Silvia

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74 Compromised bone cell differentiation in the osteogenesis imperfecta zebrafish model Chihuahua Daponte, Valentina

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75 Connecting HIPPO signaling to chromatin action during early osteoblast differentiation Caci, Atenisa

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76 Contents page
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77 Crispant screening in zebrafish as a promising approach for rapid functional screening of osteoporosis candidate genes Debaenst, Sophie

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78 CRISPR/Cas9-mediated rescue of osteoclast function in a stem cell-based disease model for osteopetrosis Gajewski, Dario

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79 Current prevalence and patterns of anti-osteoporotic drug use based on real-world nation-wide data on 8,641,341 individuals Yavropoulou, Maria

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80 3D cell culture model for differentiated natural osteocytes without artificial additives Solberg, Lene

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81 Decreases in pediatric fractures during the COVID-19 pandemic – a nationwide epidemiological cohort study Zacay, Galia

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82 Deep learning-based algorithms to detect vertebral fractures and osteoporosis using lateral spine X-ray radiograph Hong, Namki

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83 Deep Learning-Enhanced Genetic Analysis of Mandibular Cortical Thickness Reveals Shared Biologic Background with the Whole-Body Skeleton Prijatelj, Vid

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84 Defective bone repair of the mandible is rescued by FGFR3 antagonists in a Fgfr3N534K/+ mouse model of hypochondroplasia Morice, Anne

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85 Defining the role of P2X4 receptor in the prostate cancer bone metastasis He, Jiepei

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86 Degenerative Changes in the Osteocyte Network in Prematurely Aging PolgA Mice Yilmaz, Dilara

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87 Depletion of TRAP/Acp5 abolishes the bone forming effects of mechanical loading in male mice Rathod, Bhavik

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88 Determinants of Vitamin D Levels in Women Treated for Breast Cancer: a baseline analysis of data from DEDiCa trial Fassio, Angelo

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89 Development of a personalized fall rate prediction model: the GERICO cohort analysis Wapp, Christina

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90 Development of a potential clinical product for treating CLCN7-dependent Autosomal Dominant Osteopetrosis type 2 (ADO2) Maurizi, Antonio

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91 Development of diabetes-sensitive computational models of bone using finite element method for pre-clinical tracking of diabetic bone fragility Lin, Mei-Chun

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92 Development of novel therapeutic agents targeting redox regulation system in osteosarcoma Kinoshita, Hideyuki

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93 Diabetes mellitus and the benefit of antiresorptive therapy on fracture risk Eastell, Richard

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94 Differences between the effects of anti-catabolic zoledronate and anabolic teriparatide treatments on bone in adult ovariectomized rats Morko, Jukka

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95 Differences in knee osteoarthritis between surgically and chemically induced rat models Vääräniemi, Jukka

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96 Differentiating Osteocytes from BMSCs in Collagen Gel Ohlsbom, Roope

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97 Differentiation and resorption by osteoclasts derived from peripheral blood of symptomatic and asymptomatic carriers of mutations causing cherubism Dahan, Chen Abramovitch

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98 Differentiation between local and systemic associations of muscle performance and bone microarchitecture in women screened for osteoporosis Simon, Alexander

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99 Discrepancies between osteoporotic fracture evaluations in men based on German osteoporosis guidelines or the FRAX score Witzel, Judith Charlotte

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100 Disorders causing secondary hypophosphatemia in adult outpatients Puente, Nuria

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101 Distal Renal Tubular Acidosis in a Patient with Hereditary Spherocytosis and Osteoporosis: the complexity of treatment Mazeda, Carolina

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102 Does combined amplitude and high-frequency vibration, accounting for age differences, offer a perspective on efficacy and dose-response in sedentary osteopenic postmenopausal women? Fernandez, Peter

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103 Does depression influence functional recovery after an osteoporotic fracture? – a retrospective study Silva, Susana

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104 Donepezil exerted slight unfavorable effects on the musculoskeletal system in rats Londzin, Piotr

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105 Dp-ucMGP – a modulator in disease with an inflammatory component? Schweighofer, Natascha

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106 Dual-energy x-ray absorptiometry (DXA) as an imaging tool in bone and metabolic research Kähkönen, Tiina

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107 Dysregulation of MicroRNAs in Osteogenesis Imperfecta: the miROI study Mercier, Alexandre

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108 Effectiveness of pamidronate therapy in chronic recurrent multifocal osteomyelitis (CRMO) with thoracic/lumbal spine localization – a case report Opala, Aleksandra

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109 Effect of escitalopram oxalate on quality bone tissue of ovariectomized rats Shimano, Roberta Carminati

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110 Effect of hypertension on osteoblast differentiation of mesenchymal stem cells and bone repair Souza, Alann

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111 Effect of the interaction between cells from healthy and osteoporotic rats on osteoblast differentiation and bone repair Souza, Alann

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112 Effects of aging on the osteocyte lacuno-canalicular network in human osteonal bone Jones, Chloe

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113 Effects of androgen replacement therapy on bone and vascular complications in an adenine-induced CKD rat model David, Karel

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114 Effects of Encaleret (CLTX-305) on Mineral Physiology in Autosomal Dominant Hypocalcemia Type 1 Demonstrate Proof-of-Concept: Early Results from a Phase 2B, Open-Label, Dose-Ranging Study [NCT04581629] Gafni, Rachel

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115 Effects of food restriction and refeeding on bone callus: a study in rats during the growth phase Botega, Iara Inácio

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116 Effects of High-Intensity Resistance Training (HIT-RT) on Visceral Adipose Tissue and Abdominal Aortic Calcifications in Men with Osteosarcopenia Chaudry, Oliver

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117 Effects of hypobaric swimming training on trabecular bone volume and structure in old type 2 diabetic rats Tamaki, Hiroyuki

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118 Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of type 2 diabetes in rats Londzin, Piotr

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119 Effects of streptozotocin-induced diabetes on strength of the humerus in rats of different ages Torba, Alexandr

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120 Efficacy and safety with TransCon PTH for adults with hypoparathyroidism through week 84 in the PaTH Forward trial Hofbauer, Lorenz

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121 Efficiency of a remote telemedicine rehabilitation program using a special set of physical exercises in patients after COVID-19 Gilmutdinova, Ilmira

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122 Eldcalcitol prevents bone and muscle loss in ORX- mice Zhang, Haichao

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123 Eldecalcitol prevents glucocorticoid-induced osteoporosis by promoting osteoblast differentiation through Notch1/Wnt-β-catenin signaling Rong, Xing

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124 Elucidating gene regulatory mechanisms underlying human skeletal development using human pluripotent stem cell-derived bone tissues and single-cell multiome analysis Tani, Shoichiro

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125 Elucidation of cellular and molecular mechanisms underlying GPR39 regulation of bone matrix composition Chatterjee, Biplab

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126 Emerging roles of the long pentraxin PTX3 at the host-pathogen interface in Staphylococcus aureus-dependent osteomyelitis Possetti, Valentina

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127 Endothelial cells aggravate vascular smooth muscle cell calcification through a paracrine mechanism Zeper, Lara

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128 EphrinB2 in osteocytes is essential for lysosome formation and collagen arrangement Blank, Martha

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129 Epidemiology of childhood fractures in Israel during 2000-2019 Zacay, Galia

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130 ER stress reduction by 4-PBA treatment improves bone phenotypes in the Aga2 mouse model of osteogenesis imperfecta Duran, Ivan

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131 Estrogen receptor α (ERα) signaling in osteoblasts is crucial for mechanotransduction in bone fracture healing Steppe, Lena

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132 Etelcalcetide: an option to optimize control of secondary hyperparathyroidism on hemodialysis Morales, Rosa Elena Pérez

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133 Evaluating The Effect Of Food, Fasting And Exercise On Inorganic Pyrophosphate (PPi) Levels In Healthy Subjects Khursigara, Gus

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134 Evaluation of a CRISPR/Cas9-based dual-fluorescent reporter mouse model of premature aging to investigate the mechanobiology of bone regeneration Mathavan, Neashan

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135 Evaluation of response to alendronate treatment of osteoporosis using cathepsin K and other biomarkers Novac, Roxana

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136 Evaluation of serum concentration of Irisin and molecules affecting the musculoskeletal system after 10-day Bed Rest Oranger, Angela

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137 Evaluation of STMP1 as a susceptibility gene for Paget’s disease of Bone Makaram, Navnit

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138 Evaluation of the effects of histone deacetylase inhibitor PXD-101 on osteosarcoma cell lines De Martino, Viviana

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139 Evaluation of volumetric bone mineral density, bone microarchitecture and bone strength in patients with achondroplasia caused by FGFR3 c.1138G>A mutation Liang, Hanting

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140 Examining Sfrp4 Knockout Mice to Understand Metaphyseal Dysplasia in Human Pyle Disease Brommage, Robert

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141 Exercise reduces the risk of falls especially in women with polypharmacy: a two-year randomized controlled trial Tamminen, Anna-Erika

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142 Exome sequencing of 300,000 individuals implicates target genes for osteoporosis Zhou, Sirui

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143 Expression of Osteoclastic Coupling Factors and Their Receptors in Human Bone Remodeling Events Borggaard, Xenia

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144 Expression profiling of murine rankl knock-out mesenchimal stem cells during osteogenic induction reveals Fzd6 downregulation affecting downstream wnt signaling Schiavone, Maria Lucia

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145 Factors related to glucocorticoid-induced osteoporosis and fragility fractures in young subjects Florez, Helena

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146 First Interim Analysis of the International X-Linked Hypophosphataemia (XLH) Registry: Adult Population Baseline Characteristics Zillikens, Carola

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147 Fos transgenic mice display lipodystrophy, which is independent of osteosarcoma formation Luther, Julia

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148 Fragility fractures in postmenopausal women: development of 5-year prediction models using the FRISBEE study Baleanu, Felicia

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149 Functional characterization of the inward-rectifier potassium (Kir) channel family in bone cells Scala, Rosa

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150 Gait deviations are associated with reduced quality of life in children with X-linked hypophosphatemia Raimann, Adalbert

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151 GDF15, a potential marker of cell senescence, and increased risk of hip fracture Cummings, Steven

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152 Gene burden testing of a large patient cohort identifies potential gene candidates for atypical femur fractures Zhou, Wei

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153 Gene expression profiling in a mouse model of human Fibrous dysplasia reveals a role for matrix remodeling in the physiopathology of the disease Farinacci, Giorgia

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154 Generation of a Crouzon (FGFR2-C342Y) Syndrome cell line using prime-editing and characterization of Craniosynostosis patient-specific hiPSCs Gijsbertsen, Max

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155 Genetic analysis in a familial case with high bone mineral density suggests additive effects at two loci Gil, Núria Martinez

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156 Genome-wide association study identifies a novel INDEL marker associated with pediatric fracture risk Medina-Gomez, Carolina

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157 Glucose metabolism prevents ferroptosis and secures proteostasis in the developing growth plate Loopmans, Shauni

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158 Gout in Primary Hyperparathyroidism, connecting crystals to the minerals Patra, Shinjan

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159 Gut microbiome profiles identified by a machine learning algorithm are correlated with T2D and muscle strength: the Rotterdam Study Li, Ruolin

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160 Health related quality of life in patients with osteoporosis: results of a cross sectional study Mazeda, Carolina

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161 Higher Risk of Kidney Complications and Hospitalization in Patients with Chronic Hypoparathyroidism in Sweden: A Population-Based Cohort Study Björnsdottir, Sigridur

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162 High Fat Diet (HFD)-Induced Obesity Augments the Deleterious Effects of Estrogen Deficiency on Bone: Evidence from ovariectomized Mice Ali, Dalia

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163 Homeodomain transcription factor MEIS1 as a novel player regulating hMSC-TERTs osteogenic differentiation Guo, Yuan

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164 Homozygous Kdelr2-mutant mice display defects in endochondral and intramembranous bone development Stephan, Alice

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165 HR-pQCT Measures of Bone Microarchitecture in Type 1 and Type 2 Diabetes Mellitus: Systematic Review and Meta-analysis Walle, Matthias

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166 Human and Mouse Osteotropic Breast Cancer cells’ Extracellular Vesicles transfer bone cells-influencing miRNAs Ponzetti, Marco

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167 Human osteoclasts in vitro are both inhibited and stimulated dose-dependently by cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) Nielsen, Simone Snitgård Rosendal

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168 Human periodontal ligament cell lines with alkaline phosphatase mutations mimic dental aspects of hypophosphatasia Schiffmaier, Jana

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169 Icariin alleviates wear particle-induced periprosthetic osteolysis via down-regulation of the estrogen receptor α-mediated NF-κB signaling pathway in macrophages Fu, Guangtao

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170 Identification of differentially expressed immune receptor genes in osteosarcoma Payoe, Shasheen

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171 Identification of Disease Gene for Camurati-Engelmann Disease, Type II Wang, Zheng

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172 Identification of osteoblast proteins which are regulated by prostate cancer derived exosomal micro-RNAs Wood, Steven

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173 Identification of proteins which regulate the metastatic spread of breast cancer downstream of TWIST1 Wood, Steven

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174 Identification of proteomics risk markers that are related with bone mineral density and fracture Lu, Haojie

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175 Identification of three bacteria species associated with increased lean mass – The HUNT study Grahnemo, Louise

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176 IgG4-related dens osteolysis: a rare cause of odontoid fracture Oei, Ling

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177 Immunomodulation of chordoma model in zebrafish prevents tumour development and bone fusions López-Cuevas, Paco

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178 Impact of comorbidities on patterns and annual cost of anti-osteoporotic drug treatment based on real-world nation-wide data on 8,641,341 individuals Yavropoulou, Maria

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179 Impact of Leptin Receptor (LepR) Gene Deficiency and Type 2 Diabetes Mellitus on Endochondral and Intramembranous Ossification in a Rat Model Micheletti, Chiara

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180 Implementing an Osteoporosis Management Program into Your Practice, Hospital, or Organization: What Works and What Doesn't Work Williams, Kathy

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181 Inactivation of beta2-adrenergic signaling improves bone regeneration Knapstein, Paul-Richard

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182 Increased bone resorption in mice bearing WHIM Syndrome mutations does not rely on increased intrinsic OCL differentiation capacity Rouleau, Matthieu

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183 Increased expression of receptor for advanced glycation end-products in sarcopenic patient skeletal muscle Hwang, Ji Sup

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184 Increased RANK+MCSFR+ circulating pre-osteoclasts in CFTR-F508del patients is accompanied by altered osteoclast formation Sergheraert, Johan

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185 Influence of biofeedback mechanotherapy and virtual reality on gait biomechanics in patients after hip fracture Marchenkova, Larisa

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186 Infrared spectroscopy indicates altered bone turnover and mineralization in renal osteodystrophy Tong, Xiaoyu

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187 Inhibition of RANKL decreases mammary density and attenuates progestin-driven carcinogenesis in osteoporotic TgRANKL mice Kolokotroni, Anthi

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188 Inositol Phosphatase SHIP1 – a Regulator of Osteoclast Lineage Cell Development and Activity Safari, Fatemeh

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189 Insight into the bone dysplasia mechanism of CRTAP-null osteoblasts Barnes, Aileen

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190 Investigating breast cancer in an osteoporotic TgRANKL mouse model Gkikopoulou, Evi

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191 Investigating the Osteoblast-Adipocyte Lineage plasticity in vitro using human Bone Marrow Stromal progenitor cells Jamil, Ali Jasim Mohammad

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192 In vitro study of the acute inflammation set-up in Cutibacterium acnes related bone and joint infections Thoraval, Léa

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193 Irisin is a potential biomarker to predict muscular atrophy and bone loss progression in Charcot-Marie-Tooth Patients Colaianni, Graziana

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194 Is there a seasonal pattern in hip fractures before and during covid-19 pandemic? A retrospective study Azevedo, Sofia Ferreira

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195 Kinetics of bone loss in the murine hindlimb unloading model at two temperatures: standard 22°C vs. thermoneutral 28°C Garg, Priyanka

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196 Laser mediated osteoblast ablation triggers a pro-osteogenic inflammatory response regulated by reactive oxygen species and glucocorticoid signaling in zebrafish Knopf, Franziska

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197 Limitations of jaw movement in fibrodysplasia ossificans progressiva (FOP): a review Schoenmaker, Ton

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198 Lipid Signaling Mediators Regulate Bone-Muscle Crosstalk During Ageing Al Saedi, Ahmed

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199 Local microdamage accumulation and impaired osteocyte viability in human cortical bone is linked to type 1 diabetes mellitus Kolibova, Sofie

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200 Local osteocyte-synthesized 1,25(OH)2D3 stimulates fibroblast growth factor 23 Ratsma, Danielle

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201 Longitudinal assessment of physical function in adults with X-linked hypophosphatemia following initiation of burosumab therapy Orlando, Giorgio

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202 Longitudinal variations in radiographic trabecular bone texture of subchondral tibial bone for the prediction of knee osteoarthritis progression: Data from the Osteoarthritis Initiative Almhdie-Imjabbar, Ahmad

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203 Long-term high fat diet induces bone loss and dysregulation of bile acid metabolism in rats that cannot be restored by physical activity Almer, Gunter

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204 Loss of Adipogenic Dickkopf-1 prevents the expansion of bone marrow adipose tissue and tends to ameliorate bone loss under High-Fat Diet in Male Mice Daamouch, Souad

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205 Low-magnitude High-Frequency Vibration Treatment Augmented the Inflammatory Stage in Osteoporotic Fracture in vivo through the p38-MAPK Pathway Cui, Can

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206 Lrp5- and Rsk2-deficiency limit osteosarcoma growth in cFos-transgenic mice by different mechanisms Carreau, Armelle

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207 Lugol as a chemical enabler of enhanced imaging for bone-muscle tissues in fish model Donaka, Rajashekar

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208 Macrophage/Osteoclast Specific Mesoporous Silica Nanoparticles as a Drug Vehicle in Treating Inflammatory Osteolysis Karadas, Özge

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209 Mast cell deficiency improves compromised fracture healing after severe trauma Ragipoglu, Deniz

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210 Mechanical loading prevents arthritis-induced bone loss in male mice Desai, Suchita

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211 Members of Tgf-β family display dynamic expression pattern during osteoblast-osteocyte transition Kratochvílová, Adéla

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212 Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing Sivaraj, Kishor Kumar

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213 Meta-analysis of effects of romosozumab on bone mineral density in postmenopausal women with osteoporosis: Evidence from randomized controlled trials Azharuddin, Md

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214 Metabolic and transcriptomic phenotyping of osteoclasts at the single cell level to uncover OCL diversity Halper, Julia

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215 Metabolomic analysis of bone resorption in vitro provides new insights into osteoclastic action and reveals novel biomarkers Norman, Brendan

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216 Methylglyoxal affects human mesenchymal stem cell-derived osteoblast and adipocytes differentiation in vitro Waqas, Komal

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217 Microfluidics-based evidence that mesenchymal stromal cells-derived biochemical factors and biomechanical signal synergize to control endothelial cell function Zhang, Shuang

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218 Microniche of human bone marrow adipose tissue hosts progenitor cells with specific mitochondrial bioenergetics and adipogenic potential Trivanovic, Drenka

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219 Microrheology study on matrix remodelling by osteoblasts in 3D hydrogel in vitro culture Koivisto, Janne T.

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220 Microstructural alterations of superolateral femoral neck cortical bone in men with diabetes as a possible basis for fragility fractures: a cadaveric study Cirovic, Aleksandar

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221 Mild vertebral fractures – do they matter? Skjødt, Michael Kriegbaum

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222 Mitochondria dynamics and function dictate osteoblast metabolism in response to nutrients Giordano, Erika

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223 Mixed connective tissue disease (MCTD) cases in a regional Hospital: a retrospective study Gerasimou, Marina

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224 “Mixed exercise”, an activity combining intermittent and continuous running: a new approach for bone health? Wazzani, Rkia Rkia

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225 More Bone with Less Minerals: The Effects of Dietary Phosphorus on the Zebrafish Skeleton Cotti, Silvia

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226 Mosaic deletions of known genes explain skeletal dysplasias with high and low bone mass Muurinen, Mari

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227 Multiomics approach to uncover the pro-osteogenic properties of Barrier to Autointegration Protein 1 (BANF1) Puglia, Michele

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228 Mutations of the LRP6 gene and bone mineral density: a family study Puente, Nuria

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229 Myb expression during osteocyte differentiation Oralová, Veronika

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230 Nacre supplementation limits bone loss induced by ovariectomy in rats Nguyen, Dung K.

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231 Nacre supplement protects old mice from bone loss Nguyen, Dung K.

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232 New cases of rare bone and mineral conditions reported within the first 18 months of the European registry for rare bone and mineral conditions Zurita, Ana Luisa Priego

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233 New 3D system for evaluating the response of osteocyte to mechanical loading Toledano, Tamar

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234 New insight on the difference between the bone microenvironment and the mammary gland for breast cancer growth Zöller, Caren

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235 New insights in breast cancer cell stemness and dormancy in the bone microenvironment: a role for N (Neural)- Cadherin Ciocca, Michela

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236 Novel TZD analog MSDC-0602K manifests a different impact on bone and mesenchymal stem cell properties compared to classical TZDs Beňová, Andrea

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237 NOX4 deletion affects metabolic and bone parameters in animal model of high fat diet obesity Džubanová, Martina

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238 Occipital bone as an uncommon localization of tumor induced osteomalacia: case report, review of the literature and embryological considerations Colangelo, Luciano

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239 On the association between Chiari malformation type 1, bone mineral density and bone related genes Gil, Núria Martinez

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240 Opportunistically identified vertebral fractures and imminent fracture risk: Observational cohort study in 2,000 men and women with routine CT of chest and/or abdomen Skjødt, Michael Kriegbaum

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241 Opportunistically identified vertebral fractures on routine CT scans are predictive of increased mortality: Observational cohort study Skjødt, Michael Kriegbaum

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242 Optical clearing-based 3D-imaging of vascularization and mineralization of human degenerative osteochondral tissue Geurts, Jeroen

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243 Osteoblast-derived extracellular vesicles influence MNNG/HOS osteosarcoma cells, reducing their migration and affecting their metabolic activity and redox balance Ucci, Argia

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244 Osteoblasts and osteoclasts generation from iPSCs to study CFTR role in cystic fibrosis-related bone disease Dumortier, Claire

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245 Osteoblasts counteract glutaminase-dependency of breast cancer cells during bone metastasis Devignes, Claire-Sophie

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246 Osteoblast-specific deficiency of Trps1 results in low bone mass Socorro, Mairobys

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247 Osteoblast-targeted Periostin Overexpression Improves Bone Mechanical Properties in Type 2 Diabetic Db/Db Mice Delon, Sara

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248 Osteocalcin stimulates human adipocyte browning: a new element in bone-adipose tissue communication Lombardi, Giovanni

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249 Osteoclastic differentiation from PBMCs in human osteochondral explants cultured ex vivo Cramer, Esther

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250 Osteocyte lacunae in transiliac bone biopsy samples across life span Blouin, Stéphane

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251 Osteogenesis imperfecta zebrafish models to test a new combined pharmacological approach Masiero, Cecilia

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252 Osteogenically differentiated human fibroblasts – an alternative model to study bone diseases Pihlström, Sandra

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253 Osteomalacia as a complication of intravenous iron infusion: a systematic review of case-reports Vilaca, Tatiane

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254 Overexpression of Lin28a blocks mitochondrial respiration and promotes Glycolysis to induce chondrocyte reprogramming Bouchemla, Zohra

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255 Overweight Prevalence In Fragility Fractures Genrinho, Inês

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256 Paralogs of calcitonin encoding gene Venger, Olga

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257 Paralogs of human parathyroid hormone encoding gene Venger, Andrii

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258 Patient-derived disease models of non-syndromic Craniosynostosis to unravel the role of the Fuzzy Planar Cell polarity (FUZ) in craniofacial development Duarte, Filipa

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259 Perilipin-1 immunostaining improves quantitation of bone marrow adipocytes in histological bone sections Widjaja, Nicko

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260 Pharmacological inhibition of myostatin effectively ameliorates bone lesions and osteoclast formation in a 4T1 mouse mammary tumor bone metastasis model Reinhardt, Julia

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261 Pharmacological inhibition of norepinephrine reuptake improves late-stage fracture healing but exerts adverse effects on intact bone Donat, Antonia

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262 Pharmacological treatment in adult patients with CRPS-I: A systematic review and meta-analysis of randomised controlled trials Fassio, Angelo

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263 Phenotypic characteristics of a Dutch cohort of patients with X-linked osteoporosis based on PLS3 mutation Zervou, Zografia

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264 PI3Kα inhibitors block osteoprogenitor specification and the inflammatory response to prevent heterotopic ossification Deber, Alexandre

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265 Plasma protein biomarkers associated with frailty in Swedish women aged 75–85 years Mitchell, Adam

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266 PLS3 knockdown in osteocytes reduces F-actin abundance and mechanosensitivity Zhong, Wenchao

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267 Porcupine inhibition normalizes Wnt activity, osteoblast excess, and impaired erythropoiesis in myelodysplastic mice Weidner, Heike

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268 Possible association of cortical thickness with spontaneous non-traumatic fracture patterns of the humeral shaft Yasuda, Tadashi

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269 Postmortem micro-scale assessment of congestive hepatopathy induced vertebral alterations Jadzic, Jelena

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270 Prediction of an imminent fracture after an index fracture – models derived from the Frisbee cohort Iconaru, Laura

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271 Prediction of Fracture Toughness of Human Cortical Bone Using Machine Learning Unal, Mustafa

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272 Pre-osteoblast fibronectin suppresses tumor growth by acting on another bone-marrow-stromal subpopulation Lubosch, Alexander

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273 Pre-osteoblasts and endothelial progenitors differently affect homing of breast cancer cells to the bone marrow Wirth, Franziska

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274 Proportion of Patients Who Reach the BMD Surrogate Threshold Effect on Romosozumab: a Post Hoc Analysis of the Randomised FRAME and ARCH Phase 3 Trials Chapurlat, Roland

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275 Prospective observational study on tolerability of buffered soluble alendronate in patients who were unable to adhere to oral bisphosphonate tablets Gomez, Monica

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276 Proteomic analysis of caspase-9 deficient MC3T3-E1 cells Vesela, Barbora

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277 Psychosocial impact of COVID-19 pandemic on cancer patients with bone metastases (PsyCO-B): a multicentre prospective observational study D'Oronzo, Stella

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278 Radiofrequency Echographic Multi-Spectrometry (REMS) and dual-energy X-rays absorptiometry for the evaluation of bone mineral density in a peritoneal dialysis setting Fassio, Angelo

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279 Radiofrequency Echographic Multi-Spectrometry (REMS) technology and DXA for BMD assessment in kidney transplant recipients Fassio, Angelo

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280 RAI2 as a novel suppressor of cancer cell homing and survival in the bone microenvironment Pereira-Veiga, Thais

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281 Rapid preoperative predicting tools for 1-year mortality and walking ability of Asian elderly femoral neck fracture patients who planned for hip arthroplasty Fu, Guangtao

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282 Real-life short-term effectiveness of anti-osteoporotic treatments: a longitudinal cohort study Adami, Giovanni

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283 Real-world data of bone turnover markers to monitor oral bisphosphonate treatment Jorgensen, Niklas

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284 Recovery from radiation-induced damage to growth plates involves functional compensation Azar, Yashar Mehrbani

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285 Recovery of hypomineralization in auditory ossicles of vitamin D receptor (Vdr) deficient mice Delsmann, Maximilian M.

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286 Reduced sensitivity to zoledronic acid of human osteoclasts from smokers in vitro parallels their blood cells’ DNA methylation Tan, Qihua

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287 Relationship between aortic calcifications and DXA and Radiofrequency Echographic Multi-Spectrometry (REMS) acquisitions Fassio, Angelo

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288 Relationship between Low muscle mass, and Protein Intake: A preliminary study in Elderly patients with hip fracture Ha, Yong-Chan

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289 Repair of a critical-size defect in estrogen-deficient mice treated with bisphosphonates Strunz, Franziska

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290 Resveratrol-mediated reversal of Doxorubicin-induced osteoclast differentiation alleviates oxidative stress via FoxM1 expression Poudel, Sunil

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291 Retrospective study of Morphea disease the last decade in a Regional Hospital Gerasimou, Marina

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292 rhBMP6 in autologous blood coagulum with ceramics induces rapid spinal fusion in sheep Štoković, Nikola

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293 Risk factors for developing sacral insufficiency fractures Andresen, Julian Ramin

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294 Risk factors for development of Atypical Femoral Fractures in patients on long-term oral Bisphosphonate therapy Cardoso, Rui

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295 Risk factors of hyperparathyroidism in Chinese X-linked hypophosphatemia (XLH) patients: A cohort study Jin, Chen Xi

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296 Safe therapeutic gene expression by a lentiviral vector for the gene therapy of autosomal recessive osteopetrosis Capo, Valentina

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297 Safety And Efficacy Of Calcifediol 0,266 Mg Soft Capsules Compared To Cholecalciferol In Osteoporotic Women Undergoing Therapy With Alendronate Vinicola, Vincenzo

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298 Searching for a systemic phenotype in cherubism in a group of 11 cherubism patients Morice, Anne

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299 Secondary prevention of osteoporotic fractures: evaluation after two years of a Portuguese Fracture Liaison Service implementation Silva, Susana

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300 Sedentary behavior is associated with poorer bone microarchitecture at the distal tibia in older patients as assessed via high-resolution peripheral quantitative computed tomography (HR-pQCT) Heilmeier, Ursula

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301 Short- and long-term effects of PTH treatment on intracortical bone remodeling with hypoparathyroidism van Dijk, Pernille

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302 Short term effects of different doses of cholecalciferol on circulating levels of 24,25(OH)2D Pepe, Jessica

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303 Short-term exposure to fine particulate matter and risk of fragility hip fractures, a case-crossover study on 1,042 hip fractures Adami, Giovanni

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304 Spatial correlations between the local architecture of the lacunocanalicular network and the surrounding mineralized matrix in mouse tibiae Schemenz, Victoria

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305 Spatial lipidomic profiling of joint tissues using MALDI-imaging; essential role of PHOSPHO1 in growth plate lipid homeostasis Tzvetkov, Jordan

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306 Spectral-CT Assessments of a Resorbable Calcium-based Bone Implant Peña, Jaime A.

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307 Stabilization of UHRF1 in synovial fibroblasts is a novel therapeutic strategy for rheumatoid arthritis Saeki, Noritaka

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308 Strength features of the tibia in diabetic rats after repeated fracture Mosyagina, Nadezhda

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309 Strength training reduces radiation-induced bone deterioration and maintains lean mass in a rat model Mosti, Mats Peder

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310 Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome with purely osteolytic, not osteosclerotic, lesions mimicking a malignant tumor Kinoshita, Hideyuki

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311 Ten-years follow up of a woman with reccurent lymphoedema and osteolytic bone disease Mazurenko, Sergei

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312 The activity of specific hypophosphatasia-causing TNSALP mutants can be improved by increasing magnesium concentration Wiedemann, Philip

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313 The association in men and women between Growth Differentiation Factor 15, bone density and bone turnover Mattia, Lorenza

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314 The chemokine Cxcl9 is a crucial regulator of bone healing Jiang, Shan

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315 The effects of systemic and local factors on regulation of skeletal and fat tissues in a mouse model of osteogenesis imperfecta Nimni, Nitsan

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316 The effects of three different vitamin D3 supplementation regimens in deficient subjects on inflammatory cytokines – a randomised open-label parallel groups study Fassio, Angelo

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317 The effects of three different vitamin D3 supplementation regimens in deficient subjects on inflammatory cytokines – a randomised open-label parallel groups study Fassio, Angelo

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318 The European registry for rare bone and mineral conditions (EuRR-Bone): results of a survey on osteogenesis imperfecta and fibrous dysplasia McCune-Albright syndrome Zurita, Ana Luisa Priego

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319 The gap junction protein Panx3 is essential for bone regeneration+ Jiang, Shan

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320 The influence of snuff on bone accretion in late adolescence. The Fit Futures Study Nilsen, Ole Andreas

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321 The iron-sensor transferrin receptor 2 (Tfr2) regulates heterotopic ossification Baschant, Ulrike

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322 The level of awareness of osteoporosis among physicians working in the field of medical rehabilitation and the effectiveness of the educational program Marchenkova, Larisa

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323 The loss of Profilin 1 is a driver of chromosome instability in osteosarcoma di Carlo, Federica Scotto

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324 The mechanosensitive ion channel protein Piezo1 is essential for postnatal trabecular bone formation mediated by Col2a1-expressing cells Brylka, Laura

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325 The osteocyte lacunar network changes in alcoholic liver cirrhosis: an autopsy study Jadzic, Jelena

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326 The osteogenic capacity of bone marrow mesenchymal stem cells requires increased mitochondrial ATP production Guerra, Paula Fernandez

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327 The rare p.Val667Met (V667M) variant of LRP5 is responsible for bone fragility through alteration of the bone matrix quality in mice Fabre, Stephanie

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328 The regenerating zebrafish scale: a platform to study osteo-anabolic processes relevant to human skeletal diseases Bergen, Dylan

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329 There is an association between Varus proximal femoral geometry and Atypical Femoral Fractures in postmenopausal women under chronic Bisphosphonate treatment? Cardoso, Rui

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330 The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability Samvelyan, Jasmine

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331 The role of Hematopoietic Stem Cell (HSC) markers and Notch2 crosstalk in the regulation of breast cancer (BrCa) cell dormancy Maurizi, Antonio

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332 The role of TMEM38B in OI osteoblasts differentiation and mineralization Jovanovic, Milena

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333 The sqstm1tmΔUBA zebrafish model, a proof-of-concept in vivo model for Paget’s disease of bone? Huybrechts, Yentl

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334 The vitamin D receptor (VDR) is widely expressed in bone metastases of different primary origin Seiler, Jonas

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335 Thyroid hormone receptor knockout differentially affects osteoblast and osteoclast differentiation and activity in vitro Lademann, Franziska

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336 Thyroid hormones and glucocorticoids differentially regulate the expression of the irisin-encoding gene Fndc5 in murine muscle and bone Tsourdi, Elena

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337 Tissue engineered mimetic periosteum for efficient delivery of rhBMP-2 Romero-Torrecilla, Juan Antonio

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338 Title Page
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339 Tmem38b osteoblast specific knock out mouse resembles osteogenesis imperfecta type XIV Contento, Barbara Maria

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340 Transcriptome analyses to study the molecular influence of Wnt1 on osteoblasts Zhao, Wenbo

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341 Transcriptomic differences of osteocytes in response to organic versus inorganic phosphates Ratsma, Danielle

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342 Transcriptomic profiling of osteoclasts exposed to extracellular acidification Davies, Bethan

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343 Tumor-induced osteomalacia: a comprehensive clinical review of 895 cases Bosman, Ariadne

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344 Tumor induced osteomalacia: a systematic review and individual patient’s data analysis Abate, Veronica

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345 Tumor induced osteomalacia: a systematic review and individual patient’s data analysis Abate, Veronica

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346 Unfavorable effects of memantine on the rat skeletal system Londzin, Piotr

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347 Use of Bone Turnover Markers in Monitoring Osteoporosis Treatment in Patients with Fragility Fractures: Target Values and Daytime Variation Borgen, Tove Tveitan

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348 Variants in STAT4 and TMEM151B identified as potential causal factors in Early-Onset Familial Osteoporosis Schembri, Marichela

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349 Vascular calcification and osteoporosis: confounded associations or shared biologic pathways? Lu, Haojie

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350 Visceral adiposity is negatively associated with bone mineral content in CD patients Soare, Iulia Simona

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351 Vitamin D inadequacy in a Portuguese FLS – a global problem? Oliveira, Cláudia

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352 Whole Exome Sequencing in Two South-East Asian Families with Atypical Femur Fractures Zhou, Wei

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353 Wnt11f2 mutation in zebrafish leads to high bone mass and craniofacial dysmorphia in, respectively heterozygous and homozygous mutants da Silva, Caroline Caetano

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354 Zebrafish tmem38b Knock out unveils the in vivo role of Trimeric Intracellular Cation (TRIC) channel B on cell homeostasis Tonelli, Francesca

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355 Zfp687 knock-in mouse model of Paget’s disease of bone exhibits increased bone marrow adiposity preceding bone remodelling alteration Russo, Sharon

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356 Zoledronate and denosumab may affect differently γδ T lymphocytes in cancer patients at risk of developing ONJ Roato, Ilaria

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357 Zoledronate in combination with chemotherapy and surgery: Friend or foe in patients with osteosarcoma? A systematic Review and Meta-Analysis Christou, Andrea

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                             357 results found
 
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