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1 Abstracts of the ECTS Congress 2021
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2 Acetabular and femoral bone marrow in patients with hip osteoarthrosis: Cellular landscape of immune and stromal compartments Trivanovic, Drenka

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3 A collagen10a1 mutation disrupts cell polarity and causes skeletal defects in a medaka model for Schmid Metaphyseal Chondrodysplasia Tan, Wen Hui

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4 Activin-A induces differential gene expression exclusively in periodontal ligament fibroblasts from fibrodysplasia ossificans progressiva patients Schoenmaker, Ton

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5 Acute left heart failure in a McCune-Albright syndrome patient with negative preoperative cardiovascular system screening after proximal femur osteotomy – a case report Fu, Guangtao

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6 Adenosine Deaminase 2 Deficiency: Its pleiotropic manifestations may also affect bone metabolism? A case study on two homozygous female twins Marin, Erika

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7 Adipocyte accumulation-induced increased tumor burden can be abrogated by antagonization of PPARγ Gaculenko, Anastasia

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8 Adipose lipolysis is required for PTH-induced bone formation Alekos, Nathalie

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9 Alcoholic liver disease-induced changes in microstructural and mechanical properties of the femoral neck: An autopsy study Jadzic, Jelena

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10 A multi-omics approach to decipher adipocyte-induced transdifferentiation of osteoblast Quacquarelli, Federica

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11 Analysis of cell cycle related gene expression in Myb deficient mandible – a pilot study Stouracova, Sabina

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12 Analysis of disparity in hip fracture rates between the five Danish healthcare regions 2014-2018 Abrahamsen, Bo

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13 Angiogenic potential of human mesenchymal stromal cell and peripheral blood mononuclear cell co-cultures Uusitalo-Kylmälä, Liina

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14 Another player in the game: BMP signaling directly activates chordoblasts for notochord sheath mineralization and centra growth in zebrafish Pogoda, Hans-Martin

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15 A novel IFITM5 variant associates with phenotype of osteoporosis with calvarial doughnut lesions Mäkitie, Riikka

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16 A novel MEN1 pathogenic variant in a patient with MEN1 syndrome: Case report Rjoob, Hani

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17 Anti-diabetic activity of flavonoid rich fraction of Pedalium murex in the medicine: Biological importance of aldose reductase in polyol pathway for prevention of microvascular complications Patel, Dinesh Kumar

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18 Anti-hyperglycemic effect of bavachin against diabetes and related complications: Therapeutic role of adiponectin expression and GLUT4 in the medicine Patel, Dinesh Kumar

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19 Anti-inflammatory activity of bavachinin against various forms of inflammatory disorders including asthmatic inflammation: Importance of natural medicine in the current scientific research Patel, Kanika

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20 A rare case of thoracic Gorham-Stout disease presenting with recurrent pleural effusions Mohsin, Zaineb

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21 Are non-fracture vertebral deformities more prevalent in patients with osteoporotic vertebral fractures? Paggiosi, Margaret

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22 Arnold Chiari malformation (ACM) in XLH: Rare but important complication of a rare disease Mohsin, Zaineb

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23 Association between environmental air pollution and rheumatoid arthritis flares Adami, Giovanni

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24 Association between serum magnesium and hemoglobin in primary hyperparathyroidism: A 10-year retrospective study Na, Ding

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25 Association between trabecular bone score and sleep patterns: Findings from a cohort study Gkitakou, Artemis

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26 Association of circulating biomarkers with osteoporosis and sarcopenia in community-dwelling postmenopausal women in China Cheng, Qun

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27 Associations between chondrocyte transiency, bone growth and osteoarthritis pathology in surgical and non-invasive loaded murine models Samvelyan, Hasmik Jasmine

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28 Atypical type VI Osteogenesis Imperfecta mouse models the intersection of IFITM5 and SERPINF1 pathways in patients Guterman-Ram, Gali

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29 Autophagy is a critical process in osteosarcoma cancer stem cells Trojani, Marie-Charlotte

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30 A whole genome sequencing study to identify novel genetic variants associated with lean mass: Multi-ethnic meta-analysis Karasik, David

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31 A 20-year comparison of sex-specific fracture incidence between Type 1 and Type 2 diabetics and non-diabetics in Denmark Nasser, Mohamad

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32 Bi-allelic loss-of-function variants in TMEM53 cause a novel type of sclerosing bone disorder in human and mouse Guo, Long

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33 Bilirubin increases the viability of osteoclasts and up-regulates osteoclast-related microRNAs Jurado, Susana

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34 Biological potential of sinensetin in the medicine for the treatment of various forms of inflammatory disorders: Therapeutic benefit in the medicine Patel, Dinesh Kumar

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35 Bisphosphonates (BP) as a potential contributor to prostheses related stress riser fractures Michael, Atef

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36 Bisphosphonates may induce flu-like syndrome throw the activation of the interferon-I-regulated pathway Kostik, Mikhail

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37 BMD accuracy errors in phantomless calibration of CT scans – a simulation study Bartenschlager, Stefan

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38 BMP-2 signaling is enhanced in case of integrin α2β1-dependent collagen upregulation in the musculoskeletal system Brand, Melanie

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39 Bone analysis revealed high bone resorption in idiopathic osteoporosis in young adults Leger, Bastien

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40 Bone cell functions in PPIB knock-out mouse model for type IX osteogenesis imperfecta are distinct from classical dominant OI Liu, Ying

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41 Bone metabolism marker in an elderly patient with osteoarthritis of the knee joint Yonezu, Hiroshi

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42 Bone microarchitecture in patients with long-standing type 1 diabetes Sewing, Lilian

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43 Bone mineral density after combined treatment of malignant brain tumors in childhood and adolescence Golounina, Olga

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44 Bone mineral density in postmenopausal women with type 2 diabetes mellitus with and without diabetic nephropathy Monov, Simeon

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45 Bone repair of the rat calvarial defect after application of the xenogeneic biomaterials and dentin Radetić, Ana Terezija Jerbić

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46 Bone tissue and osteoblasts from X-linked type XVIII OI with defects in regulated intramembrane proteolysis have distinct features Zarei, Allahdad

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47 Breast calcification chemistry as a biomarker for progression of in-situ breast cancer Gosling, Sarah

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48 Burosumab treatment in a child with cutaneous skeletal hypophosphatemia syndrome: A case report Khadora, Manal

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49 Changes in ECM components in Osteogenesis Imperfecta type V Lam, William

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50 Changes in the microarchitecture of frequently fracturing vertebral bodies in the aging gait Guido, Schroeder

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51 Characterisation of sarcopenia via DXA measured muscle/fat mass parameters and uc-dpMGP serum levels Schweighofer, Natascha

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52 Characterization of dormancy in osteosarcoma cell lines cultured in 3D Jubelin, Camille

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53 Chemical composition of ceramics affects the longevity of CRM in posterolateral lumbar fusion achieved by rhBMP6 in autologous blood coagulum with ceramic particles in rabbits Štoković, Nikola

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54 Circulating microRNA analysis in ZDF rats as a model for the identification of biomarkers and disease mechanisms in diabetic osteopathy Vázquez, David Carro

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55 Circulating sclerostin in adult patients with tumor-induced osteomalacia comparing with X-linked hypophosphatemia Ni, Xiaolin

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56 Comparative metabolic syndrome effect on total and undercarboxylated osteocalcin in non-diabetic women Bonanno, Marina

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57 Comparison of methods to improve fracture risk assessment in Chinese diabetic postmenopausal women: A case-control study Wen, Zhangxin

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58 Complex therapy of a patient with type 2 diabetes mellitus (t2dm) and morbide obesity in rehabilitation Vasileva, Valeriia

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59 Computational anatomy and geometric shape analysis enables analysis of complex craniofacial phenotypes in zebrafish mutants Diamond, Kelly

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60 Contents page
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61 Cripto favours chondrocyte hypertrophy via TGF-beta SMAD1/5 signaling in experimental osteoarthritis Sanchez-Duffhues, Gonzalo

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62 CRISPR/Cas9 mediated dual fluorescent reporter mice to study spatial bone genomics of osteoblasts and osteoclasts in the local in vivo environment Yilmaz, Dilara

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63 DEC1 deficiency results in accelerated osteopenia through enhanced DKK1 activity and attenuated PI3KCA/Akt/GSK3β signaling Jian, Yang

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64 Deletion of Transferrin Receptor 2 (Tfr2) aggravates inflammation and bone erosion by promoting macrophage activation in inflammatory arthritis Ledesma-Colunga, Maria G.

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65 De novo serine synthesis regulates chondrocyte proliferation during endochondral ossification Stegen, Steve

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66 Depletion of odontoblasts induces dental tissue regeneration Mizoguchi, Toshihide

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67 Detection of low bone mineral density using radiofrequency echographic multi-spectrometry (REMS) in a pregnant woman with progressive scleroderma Kirilova, Elena

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68 Detraining effects on musculoskeletal parameters in early-postmenopausal osteopenic women – 3-month follow-up of the randomized controlled ACTLIFE-study Kemmler, Wolfgang

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69 Developing a service for the incidental identification of osteoporotic vertebral fractures and the secondary fragility fracture prevention using artificial intelligence Kariki, Eleni

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70 Development and external validation of nomograms for predicting one-year mortality and walking ability of Asian elderly femoral neck fracture patients after arthroplasty Fu, Guangtao

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71 Development of a disease model for autosomal recessive osteopetrosis and CRISPR/Cas9-based gene therapeutic approaches in human induced pluripotent stem cells Hennig, Floriane

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72 Development of an observational registry for genetic hypophosphatemia and acquired renal phosphate wasting in The Netherlands: ORPHOS-NED Bosman, Ariadne

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73 Development of a virtual reality-based training for the elderly with increased fracture risk to prevent falls and improve their balance Schmidt, Felix Nikolai

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74 Development of biomimetic bone matrices loaded with uranium to study the effect of this actinide on bone cells Simoneau, Bastien

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75 Development of diabetes-sensitive fracture resistance analysis using finite element method to predict diabetic bone fragility and bone quality Yavuz, Cemre

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76 Differential effects of zoledronic acid and oestrogen on anti-cancer immunity George, Chris

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77 Distinct ex vivo biomarker profiles of calcified and non-calcified acetabular labrum tissues in primary hip osteoarthritis Antoniadis, Alexander

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78 Distinct phenotypes of bone fragility in patients with type 2 diabetes mellitus depending on the presence of vascular complications: A study of three-dimensional trabecular microarchitecture Cirovic, Aleksandar

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79 Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx2 Hata, Kenji

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80 3D reconstruction of the femur based on 2D DXA images: An independent and extended evaluation Dudle, Alice

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81 Dxa-based bone strain index: A new tool to evaluate bone quality in primary hyperparathyroidism Tabacco, Gaia

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82 Early life stress does not affect bone mass in male mice but induces an osteopenic phenotype in female mice Haffner-Luntzer, Melanie

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83 Effectiveness of salvage knee rotationplasty on sarcoma around the knee in adolescents and young adults Kinoshita, Hideyuki

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84 Effect of eriocitrin on the inflammatory disorders of human being: Therapeutic potential through data analysis of scientific research work Patel, Kanika

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85 Effect of flavanols on bone turnover markers in individuals with type 2 diabetes – a 3-month randomized placebo-controlled FLAVA trial Waqas, Komal

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86 Effect of hormone replacement therapy on bone formation quality and mineralization regulation mechanisms in early postmenopausal women Gamsjaeger, Sonja

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87 Effect of resistance training on muscle texture of the thigh as measured by MRI Chaudry, Oliver

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88 Elastofibroma dorsi. An entity to consider de Dios, Blanca Varas

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89 Elevated levels of active Transforming Growth Factor β1 in the subchondral bone relate spatially to cartilage loss in human knee osteoarthritis Muratovic, Dzenita

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90 Endoplasmic Reticulum (ER) stress: A role in bone metastatic breast cancer cellular dormancy Stoker, Katie

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91 Epigenome-wide association study shows that smoking alters DNA methylation in blood cells triggering aggressive bone resorption of osteoclasts in vivo and in vitro Masmoudi, Salah Eddine

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92 Establishment of diagnostic model based on RF signal of radial quantitative ultrasound and analysis of its application value on osteoporosis diagnosis Ding, Yue

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93 Estrogen receptor α in mature osteoblasts regulate the late stage of fracture healing Ikedo, Aoi

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94 Evaluation of bone health in pediatric patients with chronic anticoagulation pharmacotherapy Raimann, Adalbert

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95 Evaluation of segmentation methods for bone implant screws on in-vivo μCT data in the MgBone study – methodological evaluation of performance and repeatability for screw materials Damm, Timo

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96 Experience of complex rehabilitation of comorbid patient with acute myocardial infarction (AIM) against background of type 2 diabetes mellitus (DM2) and obesity Vasileva, Valeriia

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97 Extracellular pH is a critical regulator of osteoclast fusion, size and activation Davies, B.K.

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98 Extracellular vesicles from metastatic prostate cancer modulate osteoblastic functions Furesi, Giulia

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99 Extramedullary erythropoiesis is activated during hematoma phase of bone healing in mice Trivanovic, Drenka

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100 Ex vivo analysis of cortical microarchitecture of the distal clavicle: Implications for surgical management of fractures Cirovic, Aleksandar

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101 Ex vivo biomarker profiling identifies Oncostatin-M as a spine osteoarthritis-specific target Roessinger, Olivier

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102 Ex vivo blockade of oxidative phosphorylation increases the regenerative potential of skeletal progenitors Tournaire, Guillaume

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103 Factors associated with osteoporosis care of men: A real-life study on a nation-wide dataset Adami, Giovanni

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104 Factors associated with postoperative acute kidney injury after surgery of osteoporotic hip fractures Kang, Joon-Soon

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105 FasL induces expression of Mmp13 and Osterix in bone cells Kratochvílová, Adéla

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106 Femoral anteversion (FNA) in individuals with X-linked hypophosphatemia (XLH) Scorcelletti, Matteo

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107 Femur specimens from type 1 diabetes mellitus individuals presented with unaffected cortical bone matrix quality, but altered cellular histomorphometry Kolibova, Sofie

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108 Fibronectin derived from osteoblastic progenitors suppresses tumour growth Lubosch, Alexander

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109 Focal fibrocartilaginous dysplasia causing unilateral tibia vara in a child Bernardi, Alexandre

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110 Forearm bone densitometry by radiography with a step-wedge phantom: A pilot study Wang, Ling

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111 Fracture distribution in elderly women: A FRISBEE sub-study Mugisha, Aude

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112 Fracture healing of the mandible is impaired in a Fgfr3N534K/+ mouse model of hypochondroplasia Morice, Anne

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113 Frequency and amplitude analyses of calcium oscillations reveals the harmony regulated by ITAM receptors during RANKL-induced osteoclastogenesis Okada, Hiroyuki

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114 From the voice of patients and caregivers: Burden of illness in infantile onset ABCC6 and ENPP1 deficiency (GACI and ARHR2) O'Brien, Christine

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115 Functional characterization of CYP1A1 variants identified in patients who sustained bisphosphonate-related atypical femoral fractures Ugartondo, Nerea

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116 Gastric inhibitory polypeptide (GIP) decreases bone resorptive activity of human osteoclasts in vitro Hansen, Morten Steen Svarer

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117 General caspase inhibition in chondrocytes – RNASeq based comparison of OPH and FMK inhibitors Veselá, Barbora

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118 Giant parathyroid adenoma miming a neck cancer associated with primary hyperparathyroidism and complete cystic transformation Carsote, Mara

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119 Glucocorticoids prolong the reversal-resorption phase delaying bone formation in intracortical remodelling compared to postmenopausal and osteoporotic women Thomsen, Lisbeth Koch

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120 Glucose metabolism via the pentose phosphate pathway controls chondrocyte survival and proteostasis during bone development Loopmans, Shauni

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121 Gross morphology of thymus and spleen in rats after formation of defect in the tibia and sodium benzoate intake Luzin, Vladyslav

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122 High-resolution three-dimensional microstructural analysis of cortex of the superolateral femoral neck in men reveals critical subregion Cirovic, Ana

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123 High-resolution three-dimensional microstructural analyzes of cortex of the superolateral femoral neck in men reveals critical subregion Cirovic, Ana

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124 Hip fracture after hospital discharge from medical wards Venkatesan, Mohanraj

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125 Hip osteoarthritis in juvenile idiopathic arthritis is complication of the disease course or side effect of systemic glucocorticosteroid treatment? Sorokina, Lubov

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126 Histone demethylase Kdm3a modulates bone formation in glucocorticoid-induced osteoporosis Arai, Makoto

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127 How the duration of energy deficit in mice model affects the body composition, bone phenotype, and bone marrow stromal cell differentiation capacity? Avilkina, Viktorija

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128 HR-pQCT-based regional analysis reveals tibial spatial variability in cortical bone tissue quality in type 2 diabetic postmenopausal women with and without history of fragility fractures Heilmeier, Ursula

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129 Human umbilical cord mesenchymal stem cells inhibited the aseptic joint loosening caused by wear particles in mice Ding, Yue

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130 Identification of bone anabolic compounds of marine origin using a zebrafish pipeline Rosa, Joana

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131 Identification of modifier genes underlying intra-familial phenotypic variability in zebrafish OI models using whole exome sequencing (WES) and linkage analysis Jarayseh, Tamara

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132 Identification of skeletal deformities towards deep phenotyping of zebrafish (Danio rerio) connective tissue disease models Debaene, Caitlin

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133 Identification of SLC4A2 as a new causal gene for osteopetrosis in human Xue, Jingyi

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134 Impact of Myb deficiency on Rank-Rankl-Opg signalling pathway in osteogenesis Oralová, Veronika

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135 Incidence and risk factors for morphometric vertebral fractures in Japanese men and women: The ROAD study 3rd to 5th surveys Horii, Chiaki

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136 Incidence and severity of ectopic ossifications in 25 adult patients with X-linked hypophosphatemia Kato, Hajime

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137 Increasing the number of dexa-scans will improve health care outcome for patients with an increased fracture risk Witteveen, Janneke

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138 Increasing the use of anti-osteoporosis medication in patients who use glucocortcoids remains a challenge Witteveen, Janneke

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139 Independent external validation of FRAX® and Garvan fracture risk calculators: A sub-study of the FRISBEE cohort Baleanu, Felicia

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140 Influence of statins on cartilage homeostasis after traumatic impact and during chondrocyte re-differentiation Riegger-Koch, Jana

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141 In healthy men, early decline in trabecular bone mineral density is, in part, related to decreases in sex steroids Banica, Thiberiu

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142 Inhibition of cyclin-dependent kinase 5 (Cdk5) increases osteoblast differentiation and bone mass through the MAPK pathway Ahmad, Mubashir

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143 Inhibition of hypoxia-induced Mucin 1 alters proteomic composition of human osteoblast-produced extracellular matrix, leading to reduced osteogenic and angiogenic potential Kumar, Pavitra

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144 Insights into bisphosphonate mediated jaw necrosis from a zebrafish model Ethiraj, Lalith Prabha

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145 Interactions between oestradiol and zoledronic acid in the bone microenvironment; physiological changes altering metastatic potential of breast cancer cells in pre- and post-menopausal women Canuas-Landero, Victor

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146 Introducing and restoring Craniosynostosis-related gene mutations using prime-editing Gijsbertsen, Max

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147 Investigating Denosumab discontinuation in the TgRANKL osteoporotic mouse model Rinotas, Vagelis

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148 Investigating the pathophysiological role of RANKL in mammary gland density and oncogenesis in osteoporotic TgRANKL mice Kolokotroni, Anthi

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149 In vivo bone microarchitecture analysis in a psoriatic arthritic patient before and after anti-TNFα treatment Soldati, Enrico

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150 Involvement of FXR in the OPG/RANKL pathway of breast and prostate cancer cells Absil, Lara

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151 Involvement of Irisin in age-related osteoporosis: positive correlation with BMD in older adult patients and inhibitory effect on the senescent marker p21 in osteoblasts Colaianni, Graziana

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152 INZ-701, a recombinant ENPP1-Fc protein, prevents ectopic mineralization in a mouse model of pseudoxanthoma elasticum Cheng, Zhiliang

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153 Kinetic reconstruction of the cancellous (Cn) and endocortical (Ec) remodelling unit reveals a net positive bone balance (BB) after 12 months of treatment with romosozumab Eriksen, Erik F.

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154 Knockout of osteopontin or bone sialoprotein induces opposite response to mechanical stimulation Maalouf, Mathieu

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155 Knock out of tmem38b by CRISPR/Cas9 in zebrafish unveils the in vivo role of Trimeric intracellular cation (TRIC) channel B on cell homeostasis Leoni, Laura

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156 Lethal osteogenesis imperfecta type XX caused by compound heterozygous frameshift mutations in MESD Stürznickel, Julian

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157 LIN28a over expression increases Chondrocyte glycolysis to induce chondrocyte reprogramming Bouchemla, Zohra

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158 Longterm outcomes of rheumatoid arthritis patients with severe osteoporosis treated with either Teriparatide or antiresorptive treatment – an observational study Hauser, Barbara

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159 Lrp5 gene knockout causes craniofacial deformities and fractures in adult zebrafish Khrystoforova, Iryna

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160 Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR-based functional screening of osteoporosis candidate genes Bek, Jan Willem

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161 Lumbar spine bone mineral density and trabecular bone score-adjusted FRAX, but not FRAX without bone mineral density, identify subclinical carotid atherosclerosis Pepe, Jessica

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162 Mapping of cortical porosity and thickness along the femoral neck identifies candidate critical spots for hip fracture in older women Cirovic, Aleksandar

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163 m6A regulated lncRNA HS3ST3B1-IT1 suppresses the development of osteoarthritis by inhibiting the ubiquitination of HS3ST3B1 protein Ma, Changyan

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164 Mast cells critically regulate bone repair and osteoclast activity under estrogen-deficient conditions Fischer, Verena

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165 Mechanical loading activates YAP/TAZ pathway and chemokines in osteocyte-like cell line MLO-Y4 Cohen-Solal, Martine

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166 MicroRNAs in diabetic bone disease: A systematic review Duseja, Ankita

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167 MicroRNAs in exosomes as circulating biomarkers for postmenopausal osteoporosis with fragility fractures Cheng, Qun

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168 Modifying of fibronectin accumulation pharmacologically diminishes bone metastasis growth by suppressing proliferation Ghura, Hiba

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169 MOF/Hip fracture ratio in a Belgian cohort of post-menopausal women (FRISBEE): Potential impact on the FRAX® score Mugisha, Aude

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170 Monitoring musculoskeletal health in zebrafish using machine learning-based locomotion tracking Fiedler, Imke Astrid Kristina

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171 Multimorbidity is associated with fragility fractures in women in Portugal Barcelos, Anabela

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172 Multiple brown tumors: A severe bone complication of pseudohypoparathyroidism after 15 years of loss of follow-up Gonnelli, Sara

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173 NaQuinate selectively synergises with in vivo mechanical loading stimuli to enhance cortical bone mass and architectural modifications Javaheri, Behzad

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174 New insights into cells of human bone marrow adipose tissue Trivanovic, Drenka

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175 Non-genotoxic conditioning to overcome transplant-related toxicity in oc/oc osteopetrotic mouse model Capo, Valentina

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176 Notch signaling contributes to articular cartilage homeostasis by suppressing differentiation of superficial zone cells Iwanaga, Yasuhide

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177 Novel BMD loci identified by whole genome sequencing and CRISPR editing in zebrafish: The NHLBI Trans-Omics for Precision Medicine (TOPMED) study Hsu, Yi-Hsiang

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178 Novel heterozygous mutations in gene SERPINH1 cause autosomal recessive osteogenesis imperfecta type X Zapata, Liliana Mejia

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179 Novel murine model of atypical type VI osteogenesis imperfecta has altered osteocyte canalicular network, disordered collagen orientation along with hypermineralization of bone matrix Hedjazi, Ghazal

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180 Nutritional characteristics and body composition of patients undertaken for hip and knee arthroplasty Fuentes, María Martín

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181 Online education improves competence in identifying fibrodysplasia ossificans progressiva (FOP) Rohani-Montez, Christy

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182 Opportunistic screening for osteoporosis using abdominal computed tomography scans in patients awaiting orthotopic liver transplantation identifies CT-attenuation as the major risk factor for vertebral fractures Nachef, Clément

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183 Osteoblast cell migration during zebrafish fin regeneration Sehring, Ivonne

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184 Osteocalcin deficiency in a mouse model of severe dominant osteogenesis imperfecta rescues metabolic but not bone phenotype Tauer, Josephine

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185 Osteogenesis imperfecta and sclerostin antibody – Histological evaluation of the bone-tendon unit in the oim mouse Chretien, Antoine

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186 Osteogenesis Imperfecta in a girl with c.441 of the 2 heterozygous dominant frameshift variant gene of COL A1 Zapata, Liliana Mejia

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187 Osteomodulin impacts positively the bone remodeling process in osteoarthritis Zappia, Jérémie

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188 Osteoporosis and recent-onset diabetes after liver transplantation: A common link? Librizzi, Soledad

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189 Osteoporosis care during the COVID-19 pandemic in the Netherlands: A national survey Peeters, Joséphine

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190 Pathogenesis of osteoporosis in patients with systemic or cutaneous mastozytosis Wilke, Christof

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191 Persistence with osteoporosis treatment in patients from the Lille University Hospital Fracture Liaison Service Delbar, Anthony

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192 Pharmacological manipulation of early zebrafish skeletal development shows an important role for Smad9 in control of skeletal progenitor populations McDonald, Georgina

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193 Phenotype of the first mouse model of Cole Carpenter Syndrome Maurizi, Antonio

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194 Physical function and mobility in adults with X-linked hypophosphatemia Orlando, Giorgio

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195 Poor trabecular microarchitecture is associated with higher fracture risk in men followed for 12 years – the prospective STRAMBO study Szulc, Pawel

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196 Prediction of total knee arthroplasty risk using fractal analysis of radiographic trabecular bone texture: Data from the Osteoarthritis Initiative Almhdie-Imjabbar, Ahmad

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197 Pregnancy-associated fracture risk in women with osteogenesis imperfecta, a nationwide register-based SCCS Lykking, Emilie Karense

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198 Prevalence of monogenic bone disorders in a Dutch cohort of AFF patients Zhou, Wei

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199 Prevalence of vertebral fractures and non-fracture deformities in young healthy men De Smet, Stephanie

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200 Pronounced microarchitectural trabecular variations within the inferomedial femoral neck may potentially contribute to postoperative complication occurrence: A cadaveric study Cirovic, Ana

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201 Quality of life changes in women with osteoporotic vertebral fractures and possibility of its improvement using new complex of physical therapy including mechanotheraputic technologies Marchenkova, Larisa

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202 Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage Dou, Zelong

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203 Reactive oxygen species lead to age-related bone loss by accelerating senescence of osteoblasts in mice Ramge, Jan-Moritz

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204 Reciprocal protein stabilization of ABL and TAZ regulates osteoblastogenesis and embryonic bone development through transcription factor RUNX2 Matsumoto, Yoshinori

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205 Repair of a critical size defect in osteoporotic mice Strunz, Franziska

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206 Retrospective study of effects of hypomagnesemia on severity of primary hyperparathyroidism Na, Ding

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207 Reversal of Doxorubicin-induced bone loss by antioxidant supplement Poudel, Sunil

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208 Risk factors for imminent fractures: A substudy of the Frisbee cohort Iconaru, Laura

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209 Risk of fracture in patients with glucocorticoid requiring diseases Adami, Giovanni

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210 Risk of sarcopoenia and prevention of disability in post COVID 19 elderly patients D'Amico, Ferdinando

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211 Screening for osteoporosis in pediatric patients with Glass syndrome is strongly recommended Dittrich, Anne

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212 Screening of osteogenesis related gene expression in caspase-8 deficient MC3T3-E1 cells Vesela, Barbora

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213 Search for epigenetic markers of osteoporosis formation Yalaev, Bulat

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214 Septic knee arthritis in the emergency department of a tertiary hospital de Dios, Blanca Varas

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215 Sequential dosing with zoledronate following OPG:Fc treatment protects against rebound bone loss Zamerli, Jad

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216 Severe courses of neonatal FHH in paternally inherited CaSR mutations: Implications for perinatal monitoring and treatment Höppner, Jakob

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217 Single cell mapping of osteoclasts reveals their heterogeneity and highlights the importance of TLR2 in controlling inflammatory osteoclastogenesis Halper, Julia

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218 Site-specific alterations in murine cortical bone porosity: Enlarged osteocyte lacunae and dense vascular channels in tibia inflicted with osteotropic tumor cells Hemmatian, Haniyeh

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219 Skeletal muscle cell oxidative stress as a possible therapeutic target in a sarcopenia Kinoshita, Hideyuki

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220 Skeletal variations in wild type medaka: Baseline studies on a biomedical model Di Biagio, Claudia

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221 Skin autofluoresence, a non-invasive biomarker of advanced glycation end-products (AGEs), is associated with frailty: The Rotterdam study Waqas, Komal

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222 Standardization of microstructural measurements of vertebral trabecular separation across different CT scanners for application in multicenter CT studies in osteoporosis Peña, Jaime A.

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223 S-012-1709 treatment showed increment in BMD and biochemical parameters in protein deficient condition in growing rats Singh, Krishna Bhan

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224 Structural changes of maxilla in adult rats after implantation of hydroxyapatite material OK-015 into the tibia Luzin, Vladyslav

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225 Studies of OI patient and murine osteoblasts to investigate phenotypic variability of dominant Osteogenesis Imperfecta Jovanovic, Milena

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226 Studying the role of RANKL in breast cancer and bone metastasis mouse models Gkikopoulou, Evi

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227 Subchondral vascular modifications for hydraulic pressure load transmission and osteoarthritis Beverly, Michael

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228 Successive anti-osteoporosis treatment after denosumab in the years 2011 till 2017 Witteveen, Janneke

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229 Sympathectomy as well as β2-adrenoceptor deficiency lead to exacerbation of subchondral bone changes in experimental osteoarthritis Rösch, Gundula

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230 Synchronous post-thyroidectomy hypocalcemia, Claude-Bernard-Horner syndrome and lymphocele after the removal of medullary thyroid cancer on a teenager with multiple endocrine neoplasia type 2A syndrome Carsote, Mara

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231 Targeted RNA-seq signature of breast cancer (BC) circulating tumor cells (CTCs) correlates with the onset of bone-only metastases D'oronzo, Stella

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232 Temporal trends and factors associated with vitamin D prescription and intake Adami, Giovanni

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233 Tensin-3 oppositely regulates bone mesenchymal stromal cell-derived osteogenesis and adipogenesis Zhang, Shuang

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234 Teriparatide in the treatment of chronic postoperative hypoparathyroidism in two hemodialysis patients Eremkina, Anna

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235 The anti-inflammatory potential of probiotics on skeletal diseases: Systematic review and meta-analysis of randomised controlled trials Michael, Jenny

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236 The anti-SLAMF7 elotuzumab enhances ADCC activity with Th1-like γδT cells towards osteoclasts and myeloma cells Tenshin, Hirofumi

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237 The Appropriate Care program in the Netherlands: Improving osteoporosis care and preventing future fractures Groeneveld, Iris

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238 The assessment of fracture risk and osteoporosis rate among patients over 50 years old undergoing medical rehabilitation Marchenkova, Larisa

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239 The blood-cerebrospinal fluid barrier, an important regulator of vitamin D metabolite concentrations in the central nervous system Zelzer, Sieglinde

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240 The combination of hemodynamic alterations and endothelial dysfunction accelerates arterial media calcification in warfarin administered rats Van Den Bergh, Geoffrey

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241 The effect of food supplement with calcium and vitamin D3 on calcium homeostasis and falls incidence in patients with high fracture risk undergoing medical rehabilitation Marchenkova, Larisa

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242 The effect of three different vitamin D3 supplementation regimens in deficient subjects – a randomized open-label parallel group study Fassio, Angelo

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243 The effects of implantation of ceramic hydroxyapatite into the tibia on gross morphology of the adrenal glands Luzin, Vladyslav

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244 The effects of implantation of hydroxyapatite into the tibia and oral calcium intake on structure of the humeral shaft Luzin, Vladyslav

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245 The European Registry for Rare Bone and Mineral Conditions (EuRR-Bone): First year experience of the use of an e-reporting tool Zurita, Ana Luisa Priego

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246 The evaluation of bone union activity of freeze-dried platelet-rich plasma Kinoshita, Hideyuki

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247 The French Multicentre Elevated Bone Mass Study: Prevalence and causes Paccou, Julien

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248 The impact of Nordic walking on bone properties in postmenopausal women with pre-diabetes and non-alcohol fatty liver disease Le, Shenglong

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249 The importance of retaining physical functions to prevent skeletal-related events in multiple myeloma patients with bone disease Miki, Hirokazu

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250 The importance of TNAP/Tnap for dental development in human cell culture and in zebrafish Graser, Stephanie

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251 The inositol phosphatase SHIP1 regulates skeletal development Safari, Fatemeh

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252 Therapeutic benefit and pharmacological importance of asiaticoside for the treatment of human disorders: Role of scientific data analysis in the medicine Patel, Dinesh Kumar

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253 Therapeutic potential of astilbin on diabetes and related secondary complication ‘diabetic nephropathy’: Therapeutic potential and scientific data analysis of current research work Patel, Dinesh Kumar

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254 Therapeutic potential of tectoridin in the medicine for their hypoglycemic activity and rat lens aldose reductase inhibitory potential: Medicinal importance through scientific data analysis Patel, Dinesh Kumar

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255 The relationship between bone turnover and flu-like symptoms after zoledronate following denosumab discontinuation, the ZOLARMAB study Sølling, Anne Sophie

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256 The Rho GTPase Cdc42 modulates osteoblast number and function depending on the time of its expression Wirth, Franziska

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257 The skeletal effect of post-natal treatment with N-acetylcysteine in a diastrophic dysplasia mouse model Tota, Chiara Gramegna

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258 The use of bisphosphonates to treat osteoporosis in patients with Lysinuric Protein Intolerance Draaisma, Jos

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259 Tissue-level mechanical stimuli drive bone formation and resorption in humans and mice Walle, Matthias

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260 Title Page
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261 Trabecular bone structure in advanced chronic kidney disease: Comparison of bone biopsy assessment using microCT and histomorphometry Salam, Syazrah

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262 Transcriptome analysis of Notch2 High Breast Cancer (BrCa) cells revealed new molecular determinants of BrCa cellular dormancy in the bone/bone marrow microenvironment Ciocca, Michela

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263 Transcriptomic analysis in the TgRANKL mouse model of osteoporosis reveals miRNAs as potent regulators of bone remodeling Ioannidou, Elisavet

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264 Type 2 diabetes clusters indicate diabetes duration key in fracture risk Ghatan, Samuel

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265 Use of TNF-alpha inhibitors in rheumatoid arthritis and implications for the periodontal status: For the benefit of both? de Vries, Teun

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266 Using machine learning to automate image segmentation for analysis of in vitro osteoclast formation and bone resorption Davies, B.K.

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267 Variants in the AMER1/WTX gene as a possible cause of idiopathic osteoporosis Caetano, Caroline

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268 Variation of shape, bone structure and mineralisation of vertebral centra in young adult chihuahua, a zebrafish model for human classical osteogenesis imperfecta Cotti, Silvia

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269 Vertebral fracture assessment in post-surgical hypoparathyroidism Cipriani, Cristiana

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270 Vertebral fractures in Ireland: A sub-analysis of the DXA HIP Project Carey, John

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271 Vfrac – a simple clinical tool that identifies older women with back pain at high risk of osteoporotic vertebral fractures Clark, Emma

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272 Vitamin D levels in type 1 diabetes with and without neuropathy; A case-control study Vilaca, Tatiane

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273 Vitamin D receptor regulates proliferation and differentiation of thyroid carcinoma via the E-cadherin-β-catenin complex Ling, Yali

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274 Vitamin D supplementation reduces the risk of fall in the vitamin D deficient elderly: An updated systematic review and meta-analysis Ling, Yali

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275 Water bound to hydroxyproline is correlated with post-yield mechanical properties of human cortical bone Unal, Mustafa

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276 Week 26 results from the PaTH Forward Open-Label Extension Trial Support TransCon PTH as a potential hormone replacement therapy for patients with hypoparathyroidism Rejnmark, Lars

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277 Whole-Body Vibration (WBV) affects perichordal and endochondral bone development and patterning in zebrafish larvae Jeradi, Shirine

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278 WNT16 variants influence site-specific bone mass determination and fracture risk in Maltese postmenopausal women Formosa, Melissa M.

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279 ZEB1 mediates bone marrow mesenchymal stem cell osteogenic differentiation in vivo and vitro partly through Wnt/β-catenin pathway Cheng, Qun

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280 Zebrafish as a model to assess the effects of thalidomide in limb development Varela, Débora

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281 Zoledronic acid effectively inhibited periprosthetic bone loss in patients with osteoporosis after cementless total hip arthroplasty Ding, Yue

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                             281 results found
 
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