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                             149 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses Sharma, Amit

44 5 p.
artikel
2 Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice Hu, Jia-Hua

44 5 p.
artikel
3 Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta Ganta, Krishna Kumar

44 5 p.
artikel
4 Adipocyte metabolic state regulates glial phagocytic function Alassaf, Mroj

44 5 p.
artikel
5 A left-lateralized dorsolateral prefrontal network for naming Yu, Leyao

44 5 p.
artikel
6 A miniaturized approach for robust thymus organoid production Liu, Wen

44 5 p.
artikel
7 A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons Hölbling, Benedikt V.

44 5 p.
artikel
8 An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection Walter, Zachary

44 5 p.
artikel
9 Anoctamins mediate polymodal sensory perception and larval metamorphosis in a non-vertebrate chordate Liang, Zonglai

44 5 p.
artikel
10 Anti-dengue virus antibodies that elicit complement-mediated lysis of Zika virion correlate with protection from severe dengue disease Dias Jr., Antonio G.

44 5 p.
artikel
11 A retinoic acid:YAP1 signaling axis controls atrial lineage commitment Abraham, Elizabeth

44 5 p.
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12 Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes Zhang, Jinjing

44 5 p.
artikel
13 Bactericidal activity of mammalian histones is caused by large membrane pore formation Duong, Leora

44 5 p.
artikel
14 Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling Krell, Saar

44 5 p.
artikel
15 Bile acid-FXR signaling facilitates the long-term maintenance of hepatic characteristics in human iPSC-derived organoids Shimizu, Taro

44 5 p.
artikel
16 Bilirubin metabolism in the liver orchestrates antiviral innate immunity in the body Du, Qian

44 5 p.
artikel
17 Bisphenol S induces brown adipose tissue whitening and aggravates diet-induced obesity in an estrogen-dependent manner Wen, Xue

44 5 p.
artikel
18 Cancer-induced FOXP1 disrupts and reprograms skeletal-muscle circadian transcription in cachexia Ducharme, Jeremy B.

44 5 p.
artikel
19 Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity Dang, Yifang

44 5 p.
artikel
20 Cas12h is a crRNA-guided DNA nickase that can be utilized for precise gene editing Xiang, Wenwen

44 5 p.
artikel
21 Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression Wang, Wanchen

44 5 p.
artikel
22 Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice Kim, Jung-Seok

44 5 p.
artikel
23 Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma Udutha, Suresh

44 5 p.
artikel
24 Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis Hu, Chengcheng

44 5 p.
artikel
25 Confidence bias prescribes the neurocomputational mechanism of decision-making Sun, Fanru

44 5 p.
artikel
26 Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations Bardon, Alexandra G.

44 5 p.
artikel
27 De novo serine biosynthesis is protective in mitochondrial disease Jackson, Christopher B.

44 5 p.
artikel
28 Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation Neal, Francisco E.

44 5 p.
artikel
29 DM1 repeat-expanded RNAs confer RNA toxicity as individual nuclear-retained RNAs Ouyang, John Paul Tsu

44 5 p.
artikel
30 Endophytic mycobiont provides growth benefits via a phenylpropanoid-auxin axis in host plants Chen, Cheng-Yen

44 5 p.
artikel
31 Epigenomic regulation of stemness contributes to the low immunogenicity of the most mutated human cancer Oka, Tomonori

44 5 p.
artikel
32 ER-PM tether Syt1 limits cell-to-cell connectivity via plasmodesmata during innate immune responses in Arabidopsis Li, Jiajing

44 5 p.
artikel
33 Error signals in the parvocellular division of the red nucleus, not the magnocellular division, drive adaptation in reaching Inoue, Masato

44 5 p.
artikel
34 ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion Sue, Nancy

44 5 p.
artikel
35 Essential lipids enrich membrane-associated condensates to rescue synaptic morpho-functional deficits in a mouse model of autism Arsenault, Jason

44 5 p.
artikel
36 Essential role of hepcidin in host resistance to disseminated candidiasis Arekar, Tanmay

44 5 p.
artikel
37 Establishment of a microwell-array-based miniaturized thymic organoid model suitable for high-throughput applications Major, Viktoria

44 5 p.
artikel
38 Extracellular vesicle-mediated plant miRNA trafficking regulates viral infection in insect vector Wang, Qian

44 5 p.
artikel
39 EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8+ T cells toward less-exhausted phenotypes Gramatica, Andrea

44 5 p.
artikel
40 Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones Nguyen, Long V.

44 5 p.
artikel
41 Functional-based parcellation of the mouse prefrontal cortex for network perturbation analysis Savvateev, Iurii

44 5 p.
artikel
42 Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer Catozzi, Alessia

44 5 p.
artikel
43 Functional dissection of a neuronal brain circuit mediating higher-order associative learning Rachad, El Yazid

44 5 p.
artikel
44 GATA3 differentially regulates the transcriptome via zinc finger 2-modulated phase separation Chen, Yatao

44 5 p.
artikel
45 GATA1-mediated Notch signaling augment antitumor immunity of CD11b+CD27− natural killer cells maturation via BCL9/β-catenin signal Yang, Fan

44 5 p.
artikel
46 Genetic and training adaptations in the Haenyeo divers of Jeju, Korea Aguilar-Gómez, Diana

44 5 p.
artikel
47 Genome of a stage-dependent cave-dwelling frog reveals the genetic mechanism of an extremely divergent biphasic life cycle Lu, Ningning

44 5 p.
artikel
48 Genomic context influences translesion synthesis DNA polymerase-dependent mechanisms of micronuclei induction by G-quadruplexes Pepe, Simona

44 5 p.
artikel
49 Haplotype-resolved genomes provide insights into the origins and functional significance of genome diversity in bivalves Liu, Shikai

44 5 p.
artikel
50 Hepcidin and fungal infections: The liver fights back Kuchler, Karl

44 5 p.
artikel
51 Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS Dhar, Shilpa S.

44 5 p.
artikel
52 High-confidence glycosomal membrane protein inventory unveils trypanosomal peroxin PEX15 Krishna, Chethan K.

44 5 p.
artikel
53 Hippocampus alters visual representation to encode new memory Liu, Chenhui

44 5 p.
artikel
54 Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response Chen, Chia-Yang

44 5 p.
artikel
55 How repeats rearrange chromosomes: The molecular basis of chromosomal inversions in deer mice Gozashti, Landen

44 5 p.
artikel
56 HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma Shen, Na

44 5 p.
artikel
57 Immune atlas of pituitary neuroendocrine tumors highlights endocrine-driven immune signature and therapeutic implication Guo, Xiaopeng

44 5 p.
artikel
58 Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease Eubanks, Elena

44 5 p.
artikel
59 Injecting information in the cortical reach-to-grasp network is effective in ventral but not dorsal nodes Ruszala, Brandon M.

44 5 p.
artikel
60 IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity McFadden, Michael J.

44 5 p.
artikel
61 KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway Wang, Jia-Ming

44 5 p.
artikel
62 KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation Arce, Maximiliano

44 5 p.
artikel
63 Live bacteria in gut microbiome dictate asthma onset triggered by environmental particles via modulation of DNA methylation in dendritic cells Ramar, Mohankumar

44 5 p.
artikel
64 LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression Shah, Kushani

44 5 p.
artikel
65 Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation Zaidi, Yusra

44 5 p.
artikel
66 Mapping essential somatic hypermutations in a CD4-binding site bNAb informs HIV-1 vaccine design Dam, Kim-Marie A.

44 5 p.
artikel
67 Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response Skelly, Daniel A.

44 5 p.
artikel
68 Mechanobiological mechanism of cyclic stretch-induced cell columnarization Lee, Lun-Wei

44 5 p.
artikel
69 Meningeal-derived retinoic acid regulates neurogenesis via suppression of Notch and Sox2 Como, Christina N.

44 5 p.
artikel
70 Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration Li, Zhuo

44 5 p.
artikel
71 MHC class II+ macrophage differentiation is impaired in metastasized lungs via PGE2 receptor EP2 Jeong, Mi Reu

44 5 p.
artikel
72 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity Weissenrieder, Jillian S.

44 5 p.
artikel
73 Mitochondrial GCN5L1 coordinates with YME1L and MICOS to remodel mitochondrial cristae in white adipocytes and modulate obesity Xu, Juan

44 5 p.
artikel
74 Mitochondrial protein OPA1 is required for the expansion of effector CD8 T cells Willett, Benjamin A.S.

44 5 p.
artikel
75 Molecular basis of β2 integrin activation by talin unveils subunit-specific mechanisms of integrin signaling Gao, Tong

44 5 p.
artikel
76 Multitissue single-cell analysis reveals differential cellular and molecular sensitivity between fructose and high-fat high-sucrose diets Chen, Yen-Wei

44 5 p.
artikel
77 MyD88-mediated signaling in intestinal fibroblasts regulates macrophage antimicrobial defense and prevents dysbiosis in the gut Chulkina, Marina

44 5 p.
artikel
78 Myeloid-lineage-specific membrane protein LRRC25 suppresses immunity in solid tumor and is a potential cancer immunotherapy checkpoint target Zhang, Guorong

44 5 p.
artikel
79 NANS suppresses NF-κB signaling to promote ferroptosis by perturbing iron homeostasis Wang, Ziyang

44 5 p.
artikel
80 Neural correlates of device-based sleep characteristics in adolescents Ma, Qing

44 5 p.
artikel
81 N terminus and C terminus of Arabidopsis P4-ATPase AtALA1 facilitate the detoxification of the mycotoxin deoxynivalenol in wheat Wang, Fanlong

44 5 p.
artikel
82 Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism Yang, Qiao-qiao

44 5 p.
artikel
83 Olfactory projection neuron rewiring in the brain of an ecological specialist Dürr, Benedikt R.

44 5 p.
artikel
84 Optimizing anti-PD-1/PD-L1 therapy efficacy and fecal microbiota transplantation donor selection through gut mycobiome-based enterotype Hu, Muni

44 5 p.
artikel
85 Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity Yi, Min-Hee

44 5 p.
artikel
86 OsHYPK/NatA-mediated N-terminal acetylation regulates the homeostasis of NLR immune protein to fine-tune rice immune responses and growth Huang, Yaqian

44 5 p.
artikel
87 OTUD4 inhibits ferroptosis by stabilizing GPX4 and suppressing autophagic degradation to promote tumor progression Chen, Jinglian

44 5 p.
artikel
88 Overcoming NK-mediated rejection by anti-3rd-party central memory veto CD8 T cells through downregulation of DNAM-1 on alloreactive NK cells Liu, Wei-Hsin

44 5 p.
artikel
89 Pathological α-synuclein dysregulates epitranscriptomic writer METTL3 to drive neuroinflammation in microglia Miller, Cameron

44 5 p.
artikel
90 PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape Sánchez-Álvarez, Miguel

44 5 p.
artikel
91 Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages Matsushita, Mai

44 5 p.
artikel
92 Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis Maserumule, Charlotte

44 5 p.
artikel
93 Piezo1 balances the osteogenic-tenogenic plasticity of periosteal progenitor cells through the YAP pathway Wang, Lijun

44 5 p.
artikel
94 PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain Nakazawa, Naotaka

44 5 p.
artikel
95 PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc Lacroix, Emma

44 5 p.
artikel
96 PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development Duncalf, Louise

44 5 p.
artikel
97 PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination Erickson, Benjamin

44 5 p.
artikel
98 Prefrontal ErbB4-positive interneurons for avoidance Cui, Wanpeng

44 5 p.
artikel
99 Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis Zimmerlin, Ludovic

44 5 p.
artikel
100 Pseudomonas aeruginosa clinical isolates can encode plastic-degrading enzymes that allow survival on plastic and augment biofilm formation Howard, Sophie A.

44 5 p.
artikel
101 Q&A with Bin Cao Cao, Bin

44 5 p.
artikel
102 RABC1-ABI1 module coordinates lipid droplet mobilization and post-germination growth arrest in Arabidopsis Wang, Yifei

44 5 p.
artikel
103 RabGAP1L modulates Rab7A and Rab10 to orchestrate cell-autonomous immunity Minowa-Nozawa, Atsuko

44 5 p.
artikel
104 Regulation of translation elongation and integrated stress response in heat-shocked neurons Seluzicki, Caitlin M.

44 5 p.
artikel
105 Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology Costa-Pereira, Sara

44 5 p.
artikel
106 Reliable sensory processing of superficial cortical interneurons is modulated by behavioral state Sweeney, Carolyn G.

44 5 p.
artikel
107 Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression Bresesti, Chiara

44 5 p.
artikel
108 Requirements for the neurodevelopmental disorder-associated gene ZNF292 in human cortical interneuron development and function Kaushik, Komal

44 5 p.
artikel
109 SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals Gen, Risako

44 5 p.
artikel
110 SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction Fukushima, Hidefumi

44 5 p.
artikel
111 Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer Elder, Alan M.

44 5 p.
artikel
112 Septo-subicular cholinergic circuit promotes seizure development via astrocytic inflammation Wang, Yu

44 5 p.
artikel
113 Shigella-trained pro-inflammatory macrophages protect zebrafish from secondary infection Gomes, Margarida C.

44 5 p.
artikel
114 Simultaneous in vivo multi-organ fluxomics reveals divergent metabolic adaptations in liver, heart, and skeletal muscle during obesity Rahim, Mohsin

44 5 p.
artikel
115 Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model Yu, Hanzhi

44 5 p.
artikel
116 Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues Jayasinghe, Reyka G.

44 5 p.
artikel
117 SIV proviruses seeded later in infection are harbored in short-lived CD4+ T cells Sambaturu, Narmada

44 5 p.
artikel
118 SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases Ku, Doyeong

44 5 p.
artikel
119 Somatostatin interneurons select dorsomedial striatal representations of the initial motor learning phase Rotariu, Sanziana

44 5 p.
artikel
120 Somatostatin neurons detect stimulus-reward contingencies to reduce neocortical inhibition during learning Park, Eunsol

44 5 p.
artikel
121 Staphylococcus aureus promotes strain-dependent immunopathology during cutaneous leishmaniasis through induction of IL-1β Lovins, Victoria

44 5 p.
artikel
122 Structural basis of β-glucopyranoside salicin recognition by a human bitter taste GPCR Wang, Xin

44 5 p.
artikel
123 Structural basis of human cytomegalovirus neutralization by gB AD-5-specific potent antibodies Wu, Changwen

44 5 p.
artikel
124 Structural ubiquitin contributes to K48 linkage specificity of the HECT ligase Tom1 Warner, Katrina

44 5 p.
artikel
125 Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states Li, Anna

44 5 p.
artikel
126 Synaptic vesicle fusion promotes phosphatidylinositol 4-phosphate synthesis for efficient synaptic transmission Yoshida, Tomofumi

44 5 p.
artikel
127 TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors Bhuiyan, Tanja

44 5 p.
artikel
128 Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification Guerin, Lindsey N.

44 5 p.
artikel
129 The balance between conventional and unconventional T follicular helper cells influences autoreactive B cell responses He, Chenfei

44 5 p.
artikel
130 The complete reference genome of Tartary buckwheat and its mutation library provide important resources for genetic studies and breeding Li, Hongyou

44 5 p.
artikel
131 The dual function of EMB1579 in transcription and splicing governs tissue patterning in the Arabidopsis root meristem Aljedaani, Fatimah

44 5 p.
artikel
132 The gut-brain axis mechanism of normal appetite induced by kynurenic acid Pan, Linghui

44 5 p.
artikel
133 The impact of breast radiotherapy on the tumor genome and immune ecosystem Schalck, Aislyn

44 5 p.
artikel
134 The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy Fu, Yu

44 5 p.
artikel
135 The m 5 C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism Li, Songyu

44 5 p.
artikel
136 The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions Jung, Hyeji

44 5 p.
artikel
137 The ventral CA2 region of the hippocampus and its differential contributions to social memory and social aggression Boyle, Lara M.

44 5 p.
artikel
138 Time-resolved single-cell atlas identifies the spatiotemporal transcription dynamics in vernalization response in Brassica rapa Zhang, Zhicheng

44 5 p.
artikel
139 T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity Cui, Yuanbin

44 5 p.
artikel
140 TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89 Nicastro, Raffaele

44 5 p.
artikel
141 Transcriptional landscape and chromatin accessibility reveal key regulators for liver regenerative initiation and organoid formation Lian, Jiabei

44 5 p.
artikel
142 Transcription factor cooperativity at a GATA3 tandem DNA sequence determines oncogenic enhancer-mediated activation Costa, Joana R.

44 5 p.
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143 Transfer of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition Fahoum, Jamal

44 5 p.
artikel
144 Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response Wang, Zhuo

44 5 p.
artikel
145 UFMylation safeguards human hepatocyte differentiation and liver homeostasis by regulating ribosome dissociation Yang, Shuchun

44 5 p.
artikel
146 Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells Higaki, Kei

44 5 p.
artikel
147 Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection Smyth, Danielle J.

44 5 p.
artikel
148 Wolbachia-mediated reduction in the glutamate receptor mGluR promotes female promiscuity and bacterial spread Warecki, Brandt

44 5 p.
artikel
149 YAP/TAZ activity in PDGFRα-expressing alveolar fibroblasts modulates AT2 proliferation through Wnt4 Song, Jane Y.

44 5 p.
artikel
                             149 gevonden resultaten
 
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