| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Aloe-emodin alleviates cerebral ischemia-reperfusion injury by regulating microglial polarization and pyroptosis through inhibition of NLRP3 inflammasome activation
|
Li, Xun
|
|
|
129 |
C |
p.
|
artikel
|
| 2 |
A mini-review of the anti-SARS-CoV-2 potency of Amaryllidaceae alkaloids
|
Le, Ngoc-Thao-Hien
|
|
|
129 |
C |
p.
|
artikel
|
| 3 |
Androsin alleviates non-alcoholic fatty liver disease by activating autophagy and attenuating de novo lipogenesis
|
Singh, Abhinav
|
|
|
129 |
C |
p.
|
artikel
|
| 4 |
Anti-aging effects of medicinal plants and their rapid screening using the nematode Caenorhabditis elegans
|
Chen, Xiaodan
|
|
|
129 |
C |
p.
|
artikel
|
| 5 |
Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments
|
Bangay, Gabrielle
|
|
|
129 |
C |
p.
|
artikel
|
| 6 |
Antidiabetic action of the Chinese formula Shouhuitongbian and the underlying mechanism associated with alteration of gut microbiota
|
Wang, Tao
|
|
|
129 |
C |
p.
|
artikel
|
| 7 |
Artificial aging conditions for Artemisia argyi leaves based on quality-inflammation-quality marker transformation
|
Guo, Xiuli
|
|
|
129 |
C |
p.
|
artikel
|
| 8 |
Atractylenolide-I Alleviates Hyperglycemia-Induced Heart Developmental Malformations through Direct and Indirect Modulation of the STAT3 Pathway
|
Wang, Mengwei
|
|
|
129 |
C |
p.
|
artikel
|
| 9 |
A versatile economic strategy by HPLC–CAD for quantification of structurally diverse markers in quality control of Shengmai Formula from raw materials to preparations
|
Liu, Longchan
|
|
|
129 |
C |
p.
|
artikel
|
| 10 |
Baicalin attenuates neuronal damage associated with SDH activation and PDK2-PDH axis dysfunction in early reperfusion
|
Liu, Kaili
|
|
|
129 |
C |
p.
|
artikel
|
| 11 |
Berberine alleviates Alzheimer's disease by regulating the gut microenvironment, restoring the gut barrier and brain-gut axis balance
|
Sun, Chunbin
|
|
|
129 |
C |
p.
|
artikel
|
| 12 |
Bergenin alleviates proliferative arterial diseases by modulating glucose metabolism in vascular smooth muscle cells
|
Song, Yujie
|
|
|
129 |
C |
p.
|
artikel
|
| 13 |
Betaine alleviates spermatogenic cells apoptosis of oligoasthenozoospermia rat model by up-regulating methyltransferases and affecting DNA methylation
|
Lin, Qiyan
|
|
|
129 |
C |
p.
|
artikel
|
| 14 |
Bushen Huoxue recipe ameliorates ovarian function via promoting BMSCs proliferation and homing to ovaries in POI mice
|
Huang, Yanjing
|
|
|
129 |
C |
p.
|
artikel
|
| 15 |
Buyang Huanwu decoction promotes angiogenesis after cerebral ischemia through modulating caveolin-1-mediated exosome MALAT1/YAP1/HIF-1α axis
|
Chen, Bowei
|
|
|
129 |
C |
p.
|
artikel
|
| 16 |
Cardioprotective effects of curcumin against Diabetic Cardiomyopathies: A systematic review and meta-analysis of preclinical studies
|
Wang, Wujiao
|
|
|
129 |
C |
p.
|
artikel
|
| 17 |
Cartilage protective and anti-edema effects of JTF in osteoarthritis via inhibiting NCOA4-HMGB1-driven ferroptosis and aquaporin dysregulation
|
Liu, Yudong
|
|
|
129 |
C |
p.
|
artikel
|
| 18 |
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells
|
Zhang, Shuo
|
|
|
129 |
C |
p.
|
artikel
|
| 19 |
Characteristics and efficacy of traditional Chinese medicine in the therapeutic strategy of chronic coronary syndrome: A systematic review and meta-analysis
|
Ma, Xiao-Hui
|
|
|
129 |
C |
p.
|
artikel
|
| 20 |
Cnicin promotes functional nerve regeneration
|
Gobrecht, Philipp
|
|
|
129 |
C |
p.
|
artikel
|
| 21 |
Co-decoction of Lilii bulbus and Radix Rehmannia Recens and its key bioactive ingredient verbascoside inhibit neuroinflammation and intestinal permeability associated with chronic stress-induced depression via the gut microbiota-brain axis
|
Mao, Qiancheng
|
|
|
129 |
C |
p.
|
artikel
|
| 22 |
Compound Shouwu Jiangzhi Granule regulates triacylglyceride synthesis to alleviate hepatic lipid accumulation
|
Qian, Fei
|
|
|
129 |
C |
p.
|
artikel
|
| 23 |
Cornus officinalis Sieb. Et Zucc. attenuates Aβ25–35-induced mitochondrial damage and neuroinflammation in mice by modulating the ERK pathway
|
Cao, Bing
|
|
|
129 |
C |
p.
|
artikel
|
| 24 |
Corrigendum to ‘Carthami flos extract against carbon tetrachloride-induced liver fibrosis via alleviating angiogenesis in mice’ Volume 108. [DOI: 10.1016/j.phymed.2022.154517].
|
Xue, Xinyan
|
|
|
129 |
C |
p.
|
artikel
|
| 25 |
Corrigendum to “Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis” [Phytomedicine. 2023 Sep; 118: 154971]
|
Qin, Tingting
|
|
|
129 |
C |
p.
|
artikel
|
| 26 |
Corrigendum to “Potent effects of dioscin against gastric cancer in vitro and in vivo in Phytomedicine, 2016; 23 (3): 274-282.”
|
Zhao, Xinwei
|
|
|
129 |
C |
p.
|
artikel
|
| 27 |
Corrigendum to “Protective effects of total flavonoids from Clinopodium chinense (Benth.) O. Ktze on myocardial injury in vivo and in vitro via regulation of Akt/Nrf2/HO-1 pathway” [Phytomedicine 40 (2018) 88–97]
|
Hai-Jing, Zhang
|
|
|
129 |
C |
p.
|
artikel
|
| 28 |
Cucurbitacin B induces ferroptosis in oral leukoplakia via the SLC7A11/mitochondrial oxidative stress pathway
|
Yang, Mengyuan
|
|
|
129 |
C |
p.
|
artikel
|
| 29 |
Curcumin-primed olfactory mucosa-derived mesenchymal stem cells mitigate cerebral ischemia/reperfusion injury-induced neuronal PANoptosis by modulating microglial polarization
|
Lan, Ziwei
|
|
|
129 |
C |
p.
|
artikel
|
| 30 |
Dauricine attenuates ovariectomized-induced bone loss and RANKL-induced osteoclastogenesis via inhibiting ROS-mediated NF-κB and NFATc1 activity
|
Lin, Xixi
|
|
|
129 |
C |
p.
|
artikel
|
| 31 |
Deciphering the therapeutic potential of SheXiangXinTongNing: Interplay between gut microbiota and brain metabolomics in a CUMS mice model, with a focus on tryptophan metabolism
|
Wang, Xiaohong
|
|
|
129 |
C |
p.
|
artikel
|
| 32 |
Detoxification and underlying mechanisms towards toxic alkaloids by Traditional Chinese Medicine processing: A comprehensive review
|
Shan, Qiyuan
|
|
|
129 |
C |
p.
|
artikel
|
| 33 |
Dihydrotanshinone I inhibits gallbladder cancer growth by targeting the Keap1-Nrf2 signaling pathway and Nrf2 phosphorylation
|
Li, Zhuang
|
|
|
129 |
C |
p.
|
artikel
|
| 34 |
Effect of Haoqin Qingdan Tang on influenza A virus through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway
|
Liang, Shiyun
|
|
|
129 |
C |
p.
|
artikel
|
| 35 |
Effects of natural extract interventions in prostate cancer: A systematic review and network meta-analysis
|
Huang, Haotian
|
|
|
129 |
C |
p.
|
artikel
|
| 36 |
Epigallocatechin gallate suppresses mitotic clonal expansion and adipogenic differentiation of preadipocytes through impeding JAK2/STAT3-mediated transcriptional cascades
|
Peng, He
|
|
|
129 |
C |
p.
|
artikel
|
| 37 |
Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway
|
Liu, Fugang
|
|
|
129 |
C |
p.
|
artikel
|
| 38 |
Ethanolic extract of Arctium lappa leaves alleviates cerebral ischemia reperfusion-induced inflammatory injury via HDAC9-mediated NF-κB pathway
|
Wang, Mengmeng
|
|
|
129 |
C |
p.
|
artikel
|
| 39 |
Euphorbia helioscopia L. exhibits promising therapeutic effects on hemangioendothelioma and melanoma through angiogenesis inhibition
|
Dou, Man
|
|
|
129 |
C |
p.
|
artikel
|
| 40 |
Exercise-induced signaling activation by Chrysanthemum zawadskii and its active compound, linarin, ameliorates age-related sarcopenia through Sestrin 1 regulation
|
Nirmala, Farida S.
|
|
|
129 |
C |
p.
|
artikel
|
| 41 |
Exploring the anti-skin inflammation substances and mechanism of Paeonia lactiflora Pall. Flower via network pharmacology-HPLC integration
|
Chen, Yuan
|
|
|
129 |
C |
p.
|
artikel
|
| 42 |
Five-layer-funnel filtering mode discovers effective components of Chinese medicine formulas: Zhishi-Xiebai-Guizhi decoction as a case study
|
Wang, Qi
|
|
|
129 |
C |
p.
|
artikel
|
| 43 |
Formosanin C inhibits pulmonary metastasis by targeting stearyl CoA desaturase-1
|
Man, Shuli
|
|
|
129 |
C |
p.
|
artikel
|
| 44 |
Gambogic acid exhibits promising anticancer activity by inhibiting the pentose phosphate pathway in lung cancer mouse model
|
Zhang, Qianyu
|
|
|
129 |
C |
p.
|
artikel
|
| 45 |
Ganoderic acid D attenuates gemcitabine resistance of triple-negative breast cancer cells by inhibiting glycolysis via HIF-1α destabilization
|
Luo, Binbin
|
|
|
129 |
C |
p.
|
artikel
|
| 46 |
Genipin ameliorates diabetic retinopathy via the HIF-1α and AGEs-RAGE pathways
|
Sun, Kexin
|
|
|
129 |
C |
p.
|
artikel
|
| 47 |
Geniposide ameliorates atherosclerosis by restoring lipophagy via suppressing PARP1/PI3K/AKT signaling pathway
|
Lin, Jinhai
|
|
|
129 |
C |
p.
|
artikel
|
| 48 |
Gentisic acid prevents colorectal cancer metastasis via blocking GPR81-mediated DEPDC5 degradation
|
Feng, Guize
|
|
|
129 |
C |
p.
|
artikel
|
| 49 |
Ginsenoside Rg5 inhibits glioblastoma by activating ferroptosis via NR3C1/HSPB1/NCOA4
|
Zhang, Guoqing
|
|
|
129 |
C |
p.
|
artikel
|
| 50 |
Gut microbiome and metabolomic profiles reveal the antiatherosclerotic effect of indole-3-carbinol in high-choline-fed ApoE-/- mice
|
He, Yuan
|
|
|
129 |
C |
p.
|
artikel
|
| 51 |
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1
|
Wang, Qiqi
|
|
|
129 |
C |
p.
|
artikel
|
| 52 |
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism
|
Gao, Li
|
|
|
129 |
C |
p.
|
artikel
|
| 53 |
Hydroethanolic extract of Cirsium setidens ameliorates doxorubicin-induced cardiotoxicity by AMPK-PGC-1α-SOD-mediated mitochondrial protection
|
Song, Ji-Hye
|
|
|
129 |
C |
p.
|
artikel
|
| 54 |
Identifying and validating potential therapeutic targets for septic heart failure and the cardioprotective effects of lycorine
|
Liu, Qiong
|
|
|
129 |
C |
p.
|
artikel
|
| 55 |
Inhibition of vascular calcification by Compound Danshen Dripping Pill through multiple mechanisms
|
Yang, Yanfang
|
|
|
129 |
C |
p.
|
artikel
|
| 56 |
Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury
|
Zhang, Yuehan
|
|
|
129 |
C |
p.
|
artikel
|
| 57 |
Integrated pharmacokinetic properties and tissue distribution of multiple active constituents in Qing-Yi Recipe: A comparison between granules and decoction
|
Ma, Shurong
|
|
|
129 |
C |
p.
|
artikel
|
| 58 |
In vitro pharmacokinetic behavior in lung of harringtonine, an antagonist of SARS-CoV-2 associated proteins: New insights of inhalation therapy for COVID-19
|
Gao, Jiapan
|
|
|
129 |
C |
p.
|
artikel
|
| 59 |
In vivo antimalarial efficacy of Artemisia afra powder suspensions
|
Walz, Annabelle
|
|
|
129 |
C |
p.
|
artikel
|
| 60 |
Lapagyl mitigates UV-induced inflammation and immunosuppression via Foxp3+ Tregs and CCL pathway: A single-cell transcriptomics study
|
Xie, Yicheng
|
|
|
129 |
C |
p.
|
artikel
|
| 61 |
Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy
|
Feng, Zhiqiang
|
|
|
129 |
C |
p.
|
artikel
|
| 62 |
Lycium barbarum glycopeptide ameliorates motor and visual deficits in autoimmune inflammatory diseases
|
Xu, Li
|
|
|
129 |
C |
p.
|
artikel
|
| 63 |
Mechanism of Nicotiflorin in San-Ye-Qing rhizome for anti-inflammatory effect in ulcerative colitis
|
Ruan, Yun
|
|
|
129 |
C |
p.
|
artikel
|
| 64 |
Modified Zhenwu Decoction suppresses chronic colitis via targeting macrophage CCR2/Fyn/p38 MAPK signaling axis
|
Mok, Heung Lam
|
|
|
129 |
C |
p.
|
artikel
|
| 65 |
Morinda Officinalis-derived extracellular vesicle-like particles: Anti-osteoporosis effect by regulating MAPK signaling pathway
|
Cao, Yue
|
|
|
129 |
C |
p.
|
artikel
|
| 66 |
Morroniside delays the progression of non-alcoholic steatohepatitis by promoting AMPK-mediated lipophagy
|
Zhang, Cong
|
|
|
129 |
C |
p.
|
artikel
|
| 67 |
Muscone restores anoikis sensitivity in TMZ-resistant glioblastoma cells by suppressing TOP2A via the EGFR/Integrin β1/FAK signaling pathway
|
Zou, Yuheng
|
|
|
129 |
C |
p.
|
artikel
|
| 68 |
Naoxintong capsule remodels gut microbiota and ameliorates early-stage atherosclerosis in apolipoprotein E-deficient mice
|
Wan, Haofang
|
|
|
129 |
C |
p.
|
artikel
|
| 69 |
Naringin as a natural candidate for anti-autoimmune hepatitis: Inhibitory potency and hepatoprotective mechanism
|
Zhu, Qiaozhen
|
|
|
129 |
C |
p.
|
artikel
|
| 70 |
Natural endoperoxides as promising anti-leishmanials
|
Sarkar, Deblina
|
|
|
129 |
C |
p.
|
artikel
|
| 71 |
Natural products and derivatives for breast cancer treatment: From drug discovery to molecular mechanism
|
Zhang, Jing
|
|
|
129 |
C |
p.
|
artikel
|
| 72 |
Optimized therapeutic potential of Yinchenhao decoction for cholestatic hepatitis by combined network meta-analysis and network pharmacology
|
Luo, Shiman
|
|
|
129 |
C |
p.
|
artikel
|
| 73 |
Oroxylin A suppresses breast cancer-induced osteoclastogenesis and osteolysis as a natural RON inhibitor
|
Chen, Yan
|
|
|
129 |
C |
p.
|
artikel
|
| 74 |
Paeoniflorin mitigates MMP-12 inflammation in silicosis via Yang-Yin-Qing-Fei Decoction in murine models
|
Li, Tian
|
|
|
129 |
C |
p.
|
artikel
|
| 75 |
Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner
|
Qian, Jun
|
|
|
129 |
C |
p.
|
artikel
|
| 76 |
Pharmacological mechanism of natural antidepressants: The role of mitochondrial quality control
|
Lv, Shimeng
|
|
|
129 |
C |
p.
|
artikel
|
| 77 |
Polygonatum sibiricum polysaccharide ameliorates skeletal muscle aging via mitochondria-associated membrane-mediated calcium homeostasis regulation
|
Chen, Wenhao
|
|
|
129 |
C |
p.
|
artikel
|
| 78 |
Polyphyllin I ameliorates gefitinib resistance and inhibits the VEGF/VEGFR2/p38 pathway by targeting HIF-1a in lung adenocarcinoma
|
Zhang, Dengtian
|
|
|
129 |
C |
p.
|
artikel
|
| 79 |
Protective effects of ginsenoside F2 on isoproterenol-induced myocardial infarction by activating the Nrf2/HO-1 and PI3K/Akt signaling pathways
|
Cui, Ying
|
|
|
129 |
C |
p.
|
artikel
|
| 80 |
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway
|
Xie, Lingpeng
|
|
|
129 |
C |
p.
|
artikel
|
| 81 |
Purple sweet potato polysaccharide ameliorates concanavalin A-induced hepatic injury by inhibiting inflammation and oxidative stress
|
Ding, Xiao
|
|
|
129 |
C |
p.
|
artikel
|
| 82 |
Regulation of hepatocyte phospholipid peroxidation signaling by a Chinese patent medicine against psychological stress-induced liver injury
|
Zhou, Qing-Qing
|
|
|
129 |
C |
p.
|
artikel
|
| 83 |
Renal protective effects and mechanisms of Astragalus membranaceus for diabetic kidney disease in animal models: An updated systematic review and meta-analysis
|
Liu, Meifang
|
|
|
129 |
C |
p.
|
artikel
|
| 84 |
Research progress of the mechanisms and applications of ginsenosides in promoting bone formation
|
Li, Ze
|
|
|
129 |
C |
p.
|
artikel
|
| 85 |
Research progress on the role and mechanism of Sirtuin family in doxorubicin cardiotoxicity
|
Zhang, Xuan
|
|
|
129 |
C |
p.
|
artikel
|
| 86 |
Rhei Radix et Rhizoma and its anthraquinone derivatives: Potential candidates for pancreatitis treatment
|
Qiu, Qi
|
|
|
129 |
C |
p.
|
artikel
|
| 87 |
Rhizoma Alismatis Decoction improved mitochondrial dysfunction to alleviate SASP by enhancing autophagy flux and apoptosis in hyperlipidemia acute pancreatitis
|
Zhang, Rongzhan
|
|
|
129 |
C |
p.
|
artikel
|
| 88 |
Rosmarinic acid plus deferasirox inhibits ferroptosis to alleviate crush syndrome-related AKI via Nrf2/Keap1 pathway
|
Qiao, Ou
|
|
|
129 |
C |
p.
|
artikel
|
| 89 |
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury
|
Zhou, Shikang
|
|
|
129 |
C |
p.
|
artikel
|
| 90 |
Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota
|
Luo, Yanqin
|
|
|
129 |
C |
p.
|
artikel
|
| 91 |
Shenfu injection targets the PI3K-AKT pathway to regulate autophagy and apoptosis in acute respiratory distress syndrome caused by sepsis
|
Chen, Juan
|
|
|
129 |
C |
p.
|
artikel
|
| 92 |
Shenqi Yizhi prescription prevents AβO-induced memory impairment in mice by regulating the contractility of brain pericytes
|
Zhao, Panpan
|
|
|
129 |
C |
p.
|
artikel
|
| 93 |
Sijunzi decoction, a classical Chinese herbal formula, improves fatigue symptoms with changes in gut microbiota in chronic fatigue syndrome: A randomized, double-blind, placebo-controlled, multi-center clinical trial
|
Dai, Liang
|
|
|
129 |
C |
p.
|
artikel
|
| 94 |
SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1α and MTP18 in oral cancer
|
Behera, Bishnu Prasad
|
|
|
129 |
C |
p.
|
artikel
|
| 95 |
Sishen Wan enhances intestinal barrier function via regulating endoplasmic reticulum stress to improve mice with diarrheal irritable bowel syndrome
|
Zhao, Yucui
|
|
|
129 |
C |
p.
|
artikel
|
| 96 |
Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma
|
Huo, Ran
|
|
|
129 |
C |
p.
|
artikel
|
| 97 |
Syringic acid attenuates acute lung injury by modulating macrophage polarization in LPS-induced mice
|
Wang, Wei-Ting
|
|
|
129 |
C |
p.
|
artikel
|
| 98 |
Systematic review on fingerprinting development to determine adulteration of Chinese herbal medicines
|
Luo, Yongdi
|
|
|
129 |
C |
p.
|
artikel
|
| 99 |
Tanshinone IIA positively regulates the Keap1-Nrf2 system to alleviate pulmonary fibrosis via the sestrin2-sqstm1 signaling axis-mediated autophagy
|
Wu, Mingyu
|
|
|
129 |
C |
p.
|
artikel
|
| 100 |
TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway
|
Lu, Si-min
|
|
|
129 |
C |
p.
|
artikel
|
| 101 |
Targeting CD8+ T cells with natural products for tumor therapy: Revealing insights into the mechanisms
|
Wang, Yuke
|
|
|
129 |
C |
p.
|
artikel
|
| 102 |
Targeting FGFR1 by β,β-dimethylacrylalkannin suppresses the proliferation of colorectal cancer in cellular and xenograft models
|
Zhao, Ran
|
|
|
129 |
C |
p.
|
artikel
|
| 103 |
Terpenoids as potential phytoconstituent in the treatment of diabetes: From preclinical to clinical advancement
|
Roy, Sukanta
|
|
|
129 |
C |
p.
|
artikel
|
| 104 |
The chemical composition, protective effect of Rheum officinale leaf juice and its mechanism against dextran sulfate sodium-induced ulcerative colitis
|
Dai, Lixia
|
|
|
129 |
C |
p.
|
artikel
|
| 105 |
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis
|
Ruan, Yang
|
|
|
129 |
C |
p.
|
artikel
|
| 106 |
The effects of Shaoma Zhijing granules and its main components on Tourette syndrome
|
Zhao, Qian
|
|
|
129 |
C |
p.
|
artikel
|
| 107 |
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy
|
Mi, Li
|
|
|
129 |
C |
p.
|
artikel
|
| 108 |
The pathological mechanisms and potential therapeutic drugs for myocardial ischemia reperfusion injury
|
Zhang, Shuo
|
|
|
129 |
C |
p.
|
artikel
|
| 109 |
The potential application and molecular mechanisms of natural products in the treatment of allergic rhinitis: A review
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