| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
71 Acinetobacter baumannii clinical isolates evade complement-mediated lysis by inhibiting the complement cascade and improperly depositing MAC
|
Magda, Michal
|
|
|
228 |
5 |
p.
|
artikel
|
| 2 |
62 Acquired ficolin-3 deficiency in patients with Systemic Lupus Erythematosus
|
Lindelöf, Linnea
|
|
|
228 |
5 |
p.
|
artikel
|
| 3 |
233 Activated C5ar1 signaling induces fibrogenic development in Mycobacterium avium (Mav)-infected mouse lungs via the proinflammatory T helper-type I cell response
|
Shivshankar, Pooja
|
|
|
228 |
5 |
p.
|
artikel
|
| 4 |
51 Activation of complement in a mouse model of severe COVID-19
|
Szachowicz, Peter
|
|
|
228 |
5 |
p.
|
artikel
|
| 5 |
87 Activation of complement pathways and formation of membrane attack complex contribute to the development of severe COVID-19
|
Ellsworth, Calder
|
|
|
228 |
5 |
p.
|
artikel
|
| 6 |
156 Activation of the complement system early on during brain death management
|
Knijff, Laura
|
|
|
228 |
5 |
p.
|
artikel
|
| 7 |
176 A genome-wide association screening of complement activation from a general population study
|
Noce, Damia
|
|
|
228 |
5 |
p.
|
artikel
|
| 8 |
226 A high dimensional analysis of the injured brain unravels the contribution of complement C3 to the immune landscape and the neurologic outcomes following traumatic brain injury
|
Toutonji, Amer
|
|
|
228 |
5 |
p.
|
artikel
|
| 9 |
7 A nanobody-based complement inhibitor targeting complement component 2 reduces hemolysis in a complement humanized mouse model of autoimmune hemolytic anemia
|
Chen, jin
|
|
|
228 |
5 |
p.
|
artikel
|
| 10 |
217 An ecotin ortholog turns out to be a potent classical pathway inhibitor and might provide information on the relative efficacy of C1r versus C1s inhibition
|
Barta, Henriett
|
|
|
228 |
5 |
p.
|
artikel
|
| 11 |
203 Annexin A2: A positive regulator of the alternative complement pathway in the kidney
|
Renner, Brandon
|
|
|
228 |
5 |
p.
|
artikel
|
| 12 |
140 A novel selective leukocyte depletion human whole blood model reveals the specific roles of monocytes and granulocytes in the cytokine response to Escherichia coli
|
Fageräng, Beatrice
|
|
|
228 |
5 |
p.
|
artikel
|
| 13 |
147 Antibodies against Streptococcus pneumoniae pneumolysin correlate with modified HDL levels and complement activation markers in peripheral arterial disease patients
|
Nissilä, Eija
|
|
|
228 |
5 |
p.
|
artikel
|
| 14 |
139 Antibodies targeting human complement receptor C3aR
|
Mariegaard, Ida
|
|
|
228 |
5 |
p.
|
artikel
|
| 15 |
243 Anti-GPC1 IgM activating the complement system is an effective treatment in a pancreatic ductal adenocarcinoma mouse model
|
Capolla, Sara
|
|
|
228 |
5 |
p.
|
artikel
|
| 16 |
34 Anti-tumor effect of resident macrophages bearing complement component C1q in targeted therapy with CD19- Chimeric antigen receptor (CAR)-T cell
|
Shabat, Yehudit
|
|
|
228 |
5 |
p.
|
artikel
|
| 17 |
18 A phase 2, open-label study evaluating the safety and efficacy of combination pozelimab and cemdisiran therapy in patients with paroxysmal nocturnal hemoglobinuria who switch from eculizumab
|
Kelly, Richard J.
|
|
|
228 |
5 |
p.
|
artikel
|
| 18 |
17 A phase 2, randomized trial evaluating the safety and efficacy of Pozelimab and Cemdisiran in patients with paroxysmal nocturnal hemoglobinuria
|
Jang, Jun-Ho
|
|
|
228 |
5 |
p.
|
artikel
|
| 19 |
25 A phase 2/3 study evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (CHAPLE disease)
|
Ozen, Ahmet
|
|
|
228 |
5 |
p.
|
artikel
|
| 20 |
42 APPARENT: A multicenter, randomized, double-blind, placebo-controlled Phase 3 study to assess the efficacy and safety of iptacopan in idiopathic (primary) immune complex-mediated membranoproliferative glomerulonephritis
|
Kavanagh, David
|
|
|
228 |
5 |
p.
|
artikel
|
| 21 |
A retrospective observational study to estimate the risk of HLA alloimmunization with blood transfusion: Can the risk be reduced by leucodepletion?
|
Pandey, Prashant
|
|
|
228 |
5 |
p.
|
artikel
|
| 22 |
199 A role for complement in sickle cell disease
|
Diatlov, Daniel
|
|
|
228 |
5 |
p.
|
artikel
|
| 23 |
124 A Role for P-selectin and complement in the pathological sequelae of Germinal Matrix Hemorrhage
|
Hatchell, Devin
|
|
|
228 |
5 |
p.
|
artikel
|
| 24 |
86 Assessing Complement Factor B Function: A Comparison of Hemolytic and Immunofixation Electrophoresis-based Assays
|
Blain, Samantha
|
|
|
228 |
5 |
p.
|
artikel
|
| 25 |
152 Assessing function and inhibition of a synthetically assembled C3 convertase using a novel functional assay
|
Butler, Samuel
|
|
|
228 |
5 |
p.
|
artikel
|
| 26 |
41 Assessing the feasibility of genetically modified porcine red blood cells as an alternative to human red blood cells for transfusion
|
Park, Sangkeun
|
|
|
228 |
5 |
p.
|
artikel
|
| 27 |
186 Assessment of immunogenicity in mice and cross-species activity of an engineered complement regulator
|
Dopler, Arthur
|
|
|
228 |
5 |
p.
|
artikel
|
| 28 |
96 Association between acute stage biomarker levels, severity and long-term outcome in COVID-19
|
Hurler, Lisa
|
|
|
228 |
5 |
p.
|
artikel
|
| 29 |
55 Association between autoantibodies and complement activation in systemic lupus erythematosus
|
Kerboua, Kheir Eddine
|
|
|
228 |
5 |
p.
|
artikel
|
| 30 |
150 Association between loss of immune checkpoint programmed cell death protein 1 and local synthesis of complement factor B in active ANCA-associated renal vasculitis
|
Tampe, Björn
|
|
|
228 |
5 |
p.
|
artikel
|
| 31 |
61 Association between novel lipoprotein particles and age-related macular degeneration
|
ten Brink, Sofie
|
|
|
228 |
5 |
p.
|
artikel
|
| 32 |
85 Association of a new variant of complement regulator FHR2 with C3 glomerulopathy
|
Perie, Luce
|
|
|
228 |
5 |
p.
|
artikel
|
| 33 |
216 Association of a new variant of complement regulator FHR2 with C3 glomerulopathy
|
Perie, Luce
|
|
|
228 |
5 |
p.
|
artikel
|
| 34 |
216 Association of a new variant of complement regulator FHR2 with C3 glomerulopathy
|
Perie, Luce
|
|
|
228 |
5 |
p.
|
artikel
|
| 35 |
143 A targeted binding and activation of native C3 without proteolytic cleavage induced by contact with biosurfaces
|
Fromell, Karin
|
|
|
228 |
5 |
p.
|
artikel
|
| 36 |
146 A transcriptome array-based approach to link SGLT-2 and tubulointerstitial synthesis of complement C5 in IgA nephropathy
|
Tampe, Björn
|
|
|
228 |
5 |
p.
|
artikel
|
| 37 |
118 Atypical haemolytic uraemic syndrome in the era of complement inhibiting therapy: The UK national cohort experience
|
Brocklebank, Vicky
|
|
|
228 |
5 |
p.
|
artikel
|
| 38 |
142 Autoantibodies against complement C1q induced by Epstein Barr Virus antigen exacerbate renal disease in lupus-prone mice
|
Tuncer, Eylul
|
|
|
228 |
5 |
p.
|
artikel
|
| 39 |
122 Autoantibodies targeting HMGB1 and the main C1s generated HMGB1 fragment in systemic lupus erythematosus: Prevalence and characterization
|
Vigne, Jeanne
|
|
|
228 |
5 |
p.
|
artikel
|
| 40 |
223 Beta cell-derived C3 is protective in a mouse model of diet-induced obesity and diabetes
|
Colineau, Lucie
|
|
|
228 |
5 |
p.
|
artikel
|
| 41 |
89 Bi-functional C5 antibody-fusion protein (LP-005) with potential best-in-class bioactivity for complement inhibition
|
Liu, Heng
|
|
|
228 |
5 |
p.
|
artikel
|
| 42 |
44 Bi-specific antibodies targeting C1q and a tumor antigen activate the complement system independent of C1q-Fc interactions
|
Dijkstra, Douwe
|
|
|
228 |
5 |
p.
|
artikel
|
| 43 |
70 C5a receptor 1 controls antigen and TLR-driven T cell proliferation and differentiation by splenic conventional type 2 dendritic cells
|
Anna Nowacka, Alicja
|
|
|
228 |
5 |
p.
|
artikel
|
| 44 |
137 CA19-9 versus an inflammatory profile in blood samples from pancreatic cancer patients
|
Solbjørg Karlsen, Eirik
|
|
|
228 |
5 |
p.
|
artikel
|
| 45 |
80 C5b-9 and Bb factor levels as potential novel biomarkers in crescentic IgA nephropathy
|
Guzzo, Gabriella
|
|
|
228 |
5 |
p.
|
artikel
|
| 46 |
33 C5 cleavage inhibition combined with C3 convertase targeting protects from disease development in a preclinical model of autoimmune skin disease
|
Laffer, Björn
|
|
|
228 |
5 |
p.
|
artikel
|
| 47 |
160 CD59, C9-lock and horse C9 all inhibit MAC assembly through similar mechanisms
|
Zelek, Wioleta
|
|
|
228 |
5 |
p.
|
artikel
|
| 48 |
103 C3d-Directed Factor H Delivers Potent and Durable Local Complement Inhibition, Disease-Modifying Efficacy, and Decreased Renal-Derived C5b-9 Without Inhibiting Systemic Complement
|
Liu, Fei
|
|
|
228 |
5 |
p.
|
artikel
|
| 49 |
187 C3 deficiency modulates the phenotypic profile of murine macrophages
|
da Silva, Tiago Francisco
|
|
|
228 |
5 |
p.
|
artikel
|
| 50 |
101 CD59 isoforms IRIS-1 and IRIS-2 are expressed in human and mouse brains, required for neurotransmitter release, and have a decreased expression in Alzheimer[StQuote]s disease patient[StQuote]s brains
|
Golec, Ewelina
|
|
|
228 |
5 |
p.
|
artikel
|
| 51 |
220 CD59-/- is protected from glucose intolerance, insulin resistance and fatty liver disease
|
Zeibak, Marian
|
|
|
228 |
5 |
p.
|
artikel
|
| 52 |
121 Cell-based assay for the measurement of complement convertase activity
|
Stasiłojć, Małgorzata
|
|
|
228 |
5 |
p.
|
artikel
|
| 53 |
78 Characterisation of CSMD1 – A complement regulator associated with schizophrenia risk
|
Byrne, Robert
|
|
|
228 |
5 |
p.
|
artikel
|
| 54 |
119 Characterising complement in amyloid-beta plaques
|
Watkins, Lewis
|
|
|
228 |
5 |
p.
|
artikel
|
| 55 |
16 Characterization and development of CSL040, a soluble truncated fragment of complement receptor 1
|
Wymann, Sandra
|
|
|
228 |
5 |
p.
|
artikel
|
| 56 |
141 Characterization of the interaction of mannose-binding lectin with variant SARS-CoV-2 spike proteins
|
Sutta, Adrian
|
|
|
228 |
5 |
p.
|
artikel
|
| 57 |
238 Characterizations of structural and functional diversities of human complement C4A and C4B allotypes
|
Zhou, Danlei
|
|
|
228 |
5 |
p.
|
artikel
|
| 58 |
94 Citrullination of C1-inhibitor as a mechanism of impaired complement inhibition in rheumatoid arthritis
|
Martin, Myriam
|
|
|
228 |
5 |
p.
|
artikel
|
| 59 |
81 Clinical and histologic correlations in C3 glomerulopathy
|
Hall, Jillian
|
|
|
228 |
5 |
p.
|
artikel
|
| 60 |
Clinical study of autonomic dysfunction in patients with autoimmune encephalitis
|
He, Jiao
|
|
|
228 |
5 |
p.
|
artikel
|
| 61 |
Comparing the expression of MiR-223-NLRP3-IL-1β axis and serum IL-1β levels in patients with severe COVID-19 and healthy individuals
|
Houshmandfar, Sheyda
|
|
|
228 |
5 |
p.
|
artikel
|
| 62 |
90 Complement activation during hypoxia-reoxygenation in human kidney epithelial cells
|
Moldakhmetova, Saltanat
|
|
|
228 |
5 |
p.
|
artikel
|
| 63 |
222 Complement Activation in Cytokine Storms Associated with COVID-19, Sepsis, and Chimeric Antigen Receptor (CAR)-T Therapy
|
Perzon, Ofer
|
|
|
228 |
5 |
p.
|
artikel
|
| 64 |
210 Complement activation in patients with ANCA-associated vasculitis – focusing on complement activation markers in remission
|
Trattner, Rebecca
|
|
|
228 |
5 |
p.
|
artikel
|
| 65 |
95 Complement-associated prothrombotic state is caused by MAC-induced lysis of cells
|
Mannes, Marco
|
|
|
228 |
5 |
p.
|
artikel
|
| 66 |
56 Complement biomarkers reflect the pathological status of neuromyelitis optica spectrum disorders
|
Inoue, Norimitsu
|
|
|
228 |
5 |
p.
|
artikel
|
| 67 |
181 Complement C7 and clusterin form a stable complex in circulation
|
Massri, Mariam
|
|
|
228 |
5 |
p.
|
artikel
|
| 68 |
182 Complement C7 and clusterin form a stable complex in circulation
|
Massri, Mariam
|
|
|
228 |
5 |
p.
|
artikel
|
| 69 |
213 Complement C3 deficiency enhances the effector function of CD8+ T cells and inhibits tumour growth
|
Pal, Pradipta
|
|
|
228 |
5 |
p.
|
artikel
|
| 70 |
178 Complement component C1q can predict patients’ response to cisplatin depending on tumour type: A step towards personalized medicine?
|
Balduit, Andrea
|
|
|
228 |
5 |
p.
|
artikel
|
| 71 |
136 Complement C1q and von Willebrand Factor interaction in atherosclerosis of human carotid artery
|
Schulz, Kristina
|
|
|
228 |
5 |
p.
|
artikel
|
| 72 |
127 Complement drives chronic inflammation and progressive hydrocephalus in murine neonatal germinal matrix hemorrhage
|
Alshareef, Mohammed
|
|
|
228 |
5 |
p.
|
artikel
|
| 73 |
200 Complement drives Parkinson’s disease neuropathology through activation of microglial C5a receptors
|
Albornoz, Eduardo
|
|
|
228 |
5 |
p.
|
artikel
|
| 74 |
126 Complement Factor I protein concentration in human plasma and ocular tissue samples stratified by AMD genotypes and phenotypes
|
Richards, Burt T.
|
|
|
228 |
5 |
p.
|
artikel
|
| 75 |
Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic
|
Hallam, T.M.
|
|
|
228 |
5 |
p.
|
artikel
|
| 76 |
91 Complement genetics: implementation of a custom made panel for genetic testing of complement-associated kidney patients
|
Kouter, Katarina
|
|
|
228 |
5 |
p.
|
artikel
|
| 77 |
129 Complement propagates visual system pathology following traumatic brain injury
|
Borucki, Davis
|
|
|
228 |
5 |
p.
|
artikel
|
| 78 |
114 Complement protein autoantibodies and increased Factor H related protein four levels may contribute to pathogenesis in IgA nephropathy
|
Simpson, Nathan
|
|
|
228 |
5 |
p.
|
artikel
|
| 79 |
194 Complement receptor 1 length polymorphism impacts microglial functions relevant to Alzheimer’s disease
|
Daskoulidou, Nikoleta
|
|
|
228 |
5 |
p.
|
artikel
|
| 80 |
117 Complement receptor 1 long homologous repeats (A, B, and C) as a novel tool to study immune-adherence functionality of human erythrocytes
|
Ghaboosh, Hiba
|
|
|
228 |
5 |
p.
|
artikel
|
| 81 |
77 Complement regulator factor H is a cofactor for thrombin in both pro- and anticoagulant roles
|
McCluskey, Genevieve
|
|
|
228 |
5 |
p.
|
artikel
|
| 82 |
184 Complement score: A novel prognostic tool in malignant pleural mesothelioma?
|
Balduit, Andrea
|
|
|
228 |
5 |
p.
|
artikel
|
| 83 |
133 Complement system activation is mediated by COVID-19 severity, inducing endothelial cell injury and cell permeability
|
Bohorquez-Hernandez, Arlette
|
|
|
228 |
5 |
p.
|
artikel
|
| 84 |
113 Complement System and leptospirosis: Understanding the role of C3 during the renal fibrosis caused during chronic infection by pathogenic leptospires in murine experimental model
|
Midon, Leonardo
|
|
|
228 |
5 |
p.
|
artikel
|
| 85 |
189 Complement system regulation and inflammation in FHR-E deficient mice
|
Ghebreslassie, Tomas
|
|
|
228 |
5 |
p.
|
artikel
|
| 86 |
151 Complement system remains unaltered in an acute schizophrenia
|
Savukoski, Susa
|
|
|
228 |
5 |
p.
|
artikel
|
| 87 |
4 Controlling the membrane attack complex
|
Bubeck, Doryen
|
|
|
228 |
5 |
p.
|
artikel
|
| 88 |
185 CPV-104, an improved recombinant variant of human complement factor H produced in moss, is a prime candidate for clinical application in complement mediated diseases
|
Tschongov, Todor
|
|
|
228 |
5 |
p.
|
artikel
|
| 89 |
28 C1q binding and complement activation by the IgM Fc-core domain
|
Pinto, Andrea J.
|
|
|
228 |
5 |
p.
|
artikel
|
| 90 |
145 C1q dependent synaptic pruning in sepsis-associated encephalopathy (SAE)
|
Candemir, Özge
|
|
|
228 |
5 |
p.
|
artikel
|
| 91 |
76 C1q-IgM interaction studies with recombinant globular C1q variants
|
Magdalena John, Maria
|
|
|
228 |
5 |
p.
|
artikel
|
| 92 |
179 C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma
|
Balduit, Andrea
|
|
|
228 |
5 |
p.
|
artikel
|
| 93 |
235 Crystallographic and SAXS structure of the immune evasive factor GAPDH from Leptospira interrogans and interaction with human C5a
|
de la Paz García, Karla
|
|
|
228 |
5 |
p.
|
artikel
|
| 94 |
207 Crystal structure of the Factor H domains 8-14 in complex with the Factor H-recruiting peptide 5C6 validates the unprecedented domain arrangement in the central segment of Factor H
|
Schmidt, Christoph
|
|
|
228 |
5 |
p.
|
artikel
|
| 95 |
35 Deciphering complement system-dependent cellular pathways in human rheumatoid arthritis synovial tissues using large single-cell computational omics
|
Vargas, Juan
|
|
|
228 |
5 |
p.
|
artikel
|
| 96 |
97 Decreased Expression of CR1 on Peripheral White Blood Cells During Acute Dengue Infection
|
Praneechit, Hansa
|
|
|
228 |
5 |
p.
|
artikel
|
| 97 |
15 Defining the impact of factor H, factor H-related 1, and factor H-related 5 on C3b deposition on mouse mesangial cells
|
Heiderscheit, Amanda
|
|
|
228 |
5 |
p.
|
artikel
|
| 98 |
73 Dengue virus NS1-epitope specific monoclonal antibodies inhibit NS1-mediated complement evasion
|
Thiemmeca, Somchai
|
|
|
228 |
5 |
p.
|
artikel
|
| 99 |
108 Design and in vitro Evaluation of Collectin-11 Antagonists for the Treatment of Ischemia-Reperfusion Injuries
|
Rabbani, Said
|
|
|
228 |
5 |
p.
|
artikel
|
| 100 |
237 Despite altered immune compartments and increased complement consumption, heterozygous C3 gain-of-function mice do not develop atypical haemolytic syndrome following exposure to various inflammatory stimuli
|
Simpson, Nathan
|
|
|
228 |
5 |
p.
|
artikel
|
| 101 |
212 Determinants resulting in high residual C5 activity in presence of Eculizumab or Coversin
|
Sichau, Jannik
|
|
|
228 |
5 |
p.
|
artikel
|
| 102 |
6 Development of a C3 humanized rat as a new model for evaluating novel C3 inhibitors
|
Chen, Jin
|
|
|
228 |
5 |
p.
|
artikel
|
| 103 |
202 Development of ex-vivo models to study complement activation in bio-incompatibility reactions induced by extracorporeal devices
|
Gaya da Costa, Mariana
|
|
|
228 |
5 |
p.
|
artikel
|
| 104 |
120 Differential complement activation in the blood of individuals at clinical high risk for psychosis compared with healthy controls
|
Kodosaki, Eleftheria
|
|
|
228 |
5 |
p.
|
artikel
|
| 105 |
116 Differential complement iC3b levels in baseline plasma of individuals at clinical high risk for psychosis
|
Kodosaki, Eleftheria
|
|
|
228 |
5 |
p.
|
artikel
|
| 106 |
13 Differential contributions of C5b-9 and C5a/C5aR pathways to microvascular and macrovascular thrombosis in complement-mediated thrombotic microangiopathy patients
|
Liu, Xiaotian
|
|
|
228 |
5 |
p.
|
artikel
|
| 107 |
112 Distinctive dosage requirements between C3 and Factor D (FD) in the activation of the alternative complement pathway
|
Wu, Xiaobo
|
|
|
228 |
5 |
p.
|
artikel
|
| 108 |
59 DNA-templated antibody complexes provide insights into the geometric requirements of human complement activation
|
Abendstein, Leoni
|
|
|
228 |
5 |
p.
|
artikel
|
| 109 |
242 Does C1q modulate myelin sheath development in zebrafish?
|
Mendez, Oscar
|
|
|
228 |
5 |
p.
|
artikel
|
| 110 |
191 Dual deficiency of C5aR1 and C5aR2 mediates neutrophil dysfunction leading to exacerbated lung injury during streptococcal pneumonia
|
Walachowski, Sarah
|
|
|
228 |
5 |
p.
|
artikel
|
| 111 |
131 Dual inhibition of the complement system and toll-like receptors prevents systemic and local kidney inflammation in mice experiencing brain death
|
Jager, Tina
|
|
|
228 |
5 |
p.
|
artikel
|
| 112 |
Editorial Board
|
|
|
|
228 |
5 |
p.
|
artikel
|
| 113 |
232 Effect of IL-1ß and C3a on complement expression and secretion on human osteoarthritic chondrocytes
|
Köck, Hannah
|
|
|
228 |
5 |
p.
|
artikel
|
| 114 |
229 Effects of combined complement complement and CD14 inhibition on Escherichia coli-induced thromboinflammation in human whole blood in the presence and absence of antibiotics
|
Joakimsen, Ingrid Sofie
|
|
|
228 |
5 |
p.
|
artikel
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| 115 |
125 Elevated expression of complement factor I in lung cancer cells associates with shorter survival – Potentially via non-canonical mechanism
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Felberg, Anna
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| 116 |
27 Elucidating the molecular mechanisms mediating the tumor suppressive actions of complement inhibitor CSMD1 in gliomas
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Tuysuz, Emre Can
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| 117 |
105 Elucidating the role of anaphylatoxins and their receptors in osteoarthritis regarding cartilage calcification
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Ruths, Leonie
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228 |
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| 118 |
72 Elucidation of novel exosite interactions in the activation and control of the classical pathway of complement
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Garrigues, Ryan
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| 119 |
138 Escherichia coli-induced platelet aggregation in human whole blood is partly dependent on complement C3b
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Landsem, Anne
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| 120 |
43 Evaluation of iptacopan in atypical hemolytic uremic syndrome: Design and rationale of the Phase 3 open-label multicenter APPELHUS study
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Kavanagh, David
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| 121 |
38 Evaluation of minimal Factor H therapy administered to kidneys during ex vivo normothermic perfusion as a treatment to improve ischaemia reperfusion injury
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Connelly, Chloe
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| 122 |
183 Exploring the role of C5aR2 in neutrophil-driven autoimmune diseases: An often overlooked player in the pathogenesis of epidermolysis bullosa acquisita
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Seiler, Daniel
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| 123 |
231 Expression and Function of Complement Components in Head and Neck Cancer: Analysis Across Various Model Systems
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Schäfer, Nicole
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| 124 |
206 Expression of complement proteins by M1 and M2 macrophages: Complement factor B induces inflammatory macrophage phenotype
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Sharma, Samriddhi
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| 125 |
45 Expression of complement regulators on red blood cell progenitors during in vitro and in vivo erythropoiesis
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de Boer, Esther C.W.
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| 126 |
107 Ex situ porcine liver machine perfusion activates the complement system and increases cytokines independent of pre-induced liver injury
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Færden, Ida H.
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| 127 |
135 External quality assurance program for diagnostic complement laboratories: Evaluation of the past six year[StQuote]s results
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Frazer-Abel, Ashley
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228 |
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| 128 |
174 Factor H-related dimer equilibrium and kinetics revealed through novel specific ELISAs
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Veuskens, Bert R.J.
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| 129 |
177 Factor H-related proteins bind to extracellular matrix components and affect complement activation
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Papp, Alexandra
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228 |
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| 130 |
144 FH desialylation as an acquired cause of Complement dysregulation in atypical Haemolytic Uraemic Syndrome
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Corvillo, Fernando
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| 131 |
162 Ficolin-2 high consumption is a hallmark of ischemic stroke with an etiology of large-artery atherosclerosis
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Mercurio, Domenico
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| 132 |
128 Finding optimal targets for complement-based cancer therapy
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Modaresahmadi, Shadan
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| 133 |
157 From parasite to therapeutic: Expression, functional characterization, and therapeutic potential of the leech-derived complement inhibitor gigastasin
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Blagojevic, Aleksandra
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| 134 |
14 Functional activity of CD35 (Complement Receptor 1; CR1) in the conversion of complement fragment iC3b to C3dg
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Fallon, Harriet
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| 135 |
54 Functional assessment of the alternative complement pathway in the first line treatment of B cell Non-Hodgkin Lymphoma
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Kerboua, Kheir Eddine
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| 136 |
180 Functional characterization of monoclonal antibodies against human complement C4 and C4BP
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Uzonyi, Barbara
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228 |
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| 137 |
159 Functional characterization of two novel Complement Factor B variants in patients with primary Immune-Complex-mediated MPGN
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Donadelli, Roberta
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| 138 |
63 Heme-induced complement activation in invasive aspergillosis
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Vieira, Luis Sordo
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| 139 |
High expression of NF-κB inducing kinase in the bulge region of hair follicle induces tumor
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Duan, Weisong
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| 140 |
40 How FHR-1 deficiency affects the infection with the malaria pathogen Plasmodium falciparum
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Reiß, Timo
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| 141 |
52 Human factor H and properdin modulate SARS-CoV-2 infection in a complement-independent manner
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Beirag, Nazar
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| 142 |
8 Humanization of the mouse anti-human complement C6 monoclonal antibody as a potential therapeutic for certain complement-mediated diseases
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Zhang, Lingjun
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| 143 |
39 Humoral complementomics – Exploration of non-invasive complement biomarkers as predictors of renal cancer progression
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Artero, Mikel Rezola
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| 144 |
29 Humoral innate immunity and acute phase proteins in COVID-19
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Garlanda, Cecilia
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| 145 |
88 Identification and characterization of a novel complement factor I-binding protein in Pasteurella multocida
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Huong Nguyen, Quynh
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| 146 |
Identification and characterization of T-cell receptors with therapeutic potential showing conserved specificity against all SARS-CoV 2 strains
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Reimann, Hannah
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| 147 |
Identification and validation of ferroptosis-related prognostic risk model and immune landscape in hepatocellular carcinoma
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Tang, Fei
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| 148 |
Identification of prognostic genes for breast cancer related to systemic lupus erythematosus by integrated analysis and machine learning
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Liang, Xiaofeng
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| 149 |
167 Immune evasion potential associated with infection type of Staphylococcus aureus
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Cranmer, Katelyn
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| 150 |
Immunostimulatory activity and safety evaluation of Bordetella bronchiseptica-derived lipopolysaccharide, a new vaccine adjuvant candidate
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Lee, You-Jeong
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| 151 |
170 Increased complement activation in recipients is associated with chronic rejection after lung transplantation
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Kulkarni, Hrishikesh
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| 152 |
53 Increased infiltration of CD4+ T cell in the complement deficient lymphedema model
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Nishioka, Toshihiko
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| 153 |
84 Inhibition of SARS-CoV-2 spike interaction with angiotensin converting enzyme-2 (ACE2) by specific antibodies is enhanced by complement, determined with a novel flow cytometry assay
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McStraw, Nikki
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| 154 |
154 Inhibition of terminal pathway activation by Diclofenac
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Zankl, Niklas
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| 155 |
172 Insulin secretion and blood glucose homeostasis in a CD59 double knockout mouse model
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Ekström, Alexander
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| 156 |
230 Interaction of factor H and factor H-related proteins with S and N proteins of SARS-CoV-2
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Barbai, Veronika H.
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| 157 |
37 Intracellular complement in atypical hemolytic-uremic syndrome
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de Castro Deus, Marina
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| 158 |
208 Intracellular C3 protects beta cells from IL-1beta-driven cytotoxicity
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Kulak, Klaudia
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| 159 |
148 Intrarenal synthesis of complement C3 localized to distinct vascular compartments in ANCA-associated renal vasculitis
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Tampe, Björn
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| 160 |
110 Investigating the Role of Complement in Cognitive Decline after Repetitive Mild Closed Head Brain Injury
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Mallah, Khalil
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| 161 |
109 Investigation of complement-related integrin receptors using a screening platform and newly developed tool compounds
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Lamers, Christina
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| 162 |
169 Involvement of PTX3 and MBL in the clearance of SARS-CoV-2 infected lung airway epithelial cells
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Zhong, Hang
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| 163 |
193 Iptacopan (LNP023) inhibits activity of FB mutants identified in patients with atypical hemolytic uremic syndrome (aHUS)
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Valéaux, Stéphanie
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| 164 |
165 IQGAP1 deficiency promotes complement activation on podocytes: New insights into the pathogenesis of kidney complement-mediated disease
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Quadri, Lisa
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| 165 |
197 Keeping properdin in check: Serum component(s) inhibit(s) the binding of properdin
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van Essen, Mieke
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106 Lack of MASP-1 results in delayed onset of albuminuria and prolonged survival in lupus-prone MRL/lpr mice
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| 167 |
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway
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Hou, Yangfan
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| 168 |
201 Leptospira interrogans leptolysin displays proteolytic activity against complement proteins
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Courrol, Daniella
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| 169 |
Limosilactobacillus fermentum modulates the gut-airway axis by improving the immune response through FOXP3 activation on combined allergic rhinitis and asthma syndrome (CARAS)
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22 Long-term efficacy and safety of pozelimab monotherapy in patients with paroxysmal nocturnal hemoglobinuria
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| 171 |
64 Loss of the complement regulator CD55 alters marginal zone B cell homeostasis
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Lee, Iris
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| 172 |
130 Low Gene Copy Numbers (GCN) of complement C4 and C4A deficiency are highly significant genetic risk factors for idiopathic inflammatory myopathies and its major subgroups
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Zhou, Danlei
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100 LPS O1-antigen-mediated complement-resistance of Klebsiella pneumoniae clinical isolates
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Masson, Frerich
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240 MASP3 deficiency ameliorates but does not completely prevent alternative pathway complement-mediated tissue injury in a factor H mutant mouse model
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Kim, Hangsoo
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195 Measurements of complement regulators in peritoneal dialysis patients
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Faria, Bernardo
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134 Mesangial cells derived complement factor H inhibits complement activation and inflammation in IgA Nephropathy
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Li, Yebei
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| 177 |
Metabolomic and proteomic analyses of primary Sjogren’s syndrome
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Zhang, Junning
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| 178 |
93 Modeling complement activation on human glomerular microvascular endothelial cells
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Stevens, Kes H.
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| 179 |
192 Molecular imaging of renal C3d deposition to monitor lupus nephritis
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Poppelaars, Felix
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| 180 |
132 Multiple pregnancy can induce preeclampsia-like changes in complement factor H-point mutation mice
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| 181 |
227 Nomacopan as an anti-shock drug for pre-hospital treatment of traumatic hemorrhage through switching the injury phenotype to survival phenotype
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239 Novel alternative polyadenylation as a post-transcriptional mechanism in C5ar1 signaling-dependent pleural hypertrophy and fibrosis in collagen-induced arthritic mice
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Shivshankar, Pooja
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204 Novel functions of complement factor H in macrophages
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| 184 |
198 Novel natural antibodies targeted against cardiolipin are associated with higher risk of rejection in kidney transplant recipients
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Petr, Vojtech
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| 185 |
57 Opsonization and efferocytosis of dying cells are modulated by the presence of malondialdehyde epitopes
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196 Oxidative stress and anaphylatoxin receptor activation control mitochondrial calcium uptake, ATP production and fission-fusion status in RPE cells
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19 Patient-reported outcomes from a phase 2, randomised trial evaluating the safety and efficacy of pozelimab and cemdisiran in patients with paroxysmal nocturnal haemoglobinuria
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| 188 |
60 Pattern recognition plays a role in the initiation of the alternative complement pathway
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| 189 |
PDE4D gene variants and haplotypes are associated with asthma and atopy in Brazilian children
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Silva, Hatilla dos Santos
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PD1 is transcriptionally regulated by LEF1 in mature T cells
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| 191 |
36 Phase 1 clinical data for single-dose subcutaneous injection of RLYB116, a C5 blocking Affibody® molecule linked to an Albumod® albumin binding domain
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Ma, Mark
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168 Placenta specific complement activation in mice produces preeclampsia phenotype and adversely affects fetal liver function
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Banadakoppa, Manu
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47 Plasma factor D cross-sectionally associates with low-grade inflammation, endothelial dysfunction and cardiovascular disease, but not with intima-media thickness or ankle-brachial index: The Maastricht Study
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Jin, Shunxin
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214 Platelets balance revascularization by anaphylatoxin C5a receptor-dependent release of paracrine factors
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211 Platelet supernatants modulate the inflammatory response in thrombocytopenic blood ex vivo
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209 Pregnancy-related Thrombotic Microangiopathy has a spectrum of underlying causes that affect vascular endothelium
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12 Prevention of terminal pathway activation improves survival in a lethal malarial infection mouse model associated with multiple organ failure
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50 Protective role of complement factor H against the development of preeclampsia
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111 Proteolytic activity of secreted proteases from pathogenic leptospires and effects on phagocytosis by murine macrophages
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RNA-Seq and ATAC-Seq analyses reveal a global transcriptional and chromatin accessibility profiling of γδ T17 differentiation from mouse spleen
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102 Role of Dengue NS1 and its Antibodies in Complement Activation in Hepatocytes
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164 Role of nutraceuticals in ameliorating inflammation in Alzheimer[StQuote]s disease
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Alruwaili, Jawaher
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218 Roles of complement C3 in non-alcoholic fatty liver disease
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Dien Nguyen, Van
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173 Roles of complement dysregulation and membrane attack complex formation in developmental synapse loss
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149 SARS-CoV-2 nucleocapsid protein is not responsible for the activation of complement lectin pathway
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245 Sez6L2 is a brain-resident complement inhibitor that is necessary for proper brain development
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Shared biomarkers of multi-tissue origin for primary Sjogren's syndrome and their importance in immune microenvironment alterations
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225 Single cell analysis (SCA) of PBMCs for a patient with congenital non-functional CD59
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Karbian, Netanel
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163 Single cell sorting and cloning of human anti-C1q autoantibodies reveals specificity for solid-phase C1q and capacity to engage Fc receptors
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| 210 |
224 Specificity vs. versatility: Exploring the selectivity profile of the leech inhibitor gigastasin for serine proteases of the complement system and other pathways
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67 Strategic targeting of complement to regulate neuroinflammation and synapse pruning in Alzheimer’s disease
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9 Structural evolution of a complement evasion determinant shapes Lyme borreliae host tropism
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10 Structure/Function Analysis of collectin-K1 and collectin-L1
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158 Structure-guided design of derivatives of the complement inhibitor compstatin with improved species specificity profiles
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23 Study of complement modulation by reactive oxygen species: Revision of existing in vitro data
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26 Sustained complement C1s inhibition with sutimlimab in patients with cold agglutinin disease results in continued efficacy during part B of the randomized placebo-controlled phase 3 CADENZA study (NCT03347422)
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Röth, Alexander
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221 SYNERGY-1: A Phase 1, first-in-human, randomized, double-blind, placebo-controlled safety, tolerability, immunogenicity, PK and PD study of KP104 in escalating single and multiple doses
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5 Synovial complement activation and imbalance after anterior cruciate ligament injury or meniscus tear as a risk factor in the development of post-traumatic osteoarthritis
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Michael Holers, V.
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99 Targeted complement inhibition using engineered bispecific antibodies that bind local antigens and endogenous complement regulators as a novel therapeutic approach
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104 Targeting terminal pathway in brain reduces complement activation and synapse loss in a mouse model of dementia
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Zelek, Wioleta
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74 αβ T cells and complement meet again: TCR crosstalk with surface complement regulators
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190 The activation of the lectin pathway serine proteases by fibrin and it’s subsequent effect in clot formation
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49 The binding and kinetics of normal versus pathogenic C3 convertase autoantibodies
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24 The C5a/C5aR1 axis controls the induction of Germinal Center B cells, their IgM/IgG1 production and plasma cell differentiation
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20 The C5aR2 pathway as a potential novel checkpoint for B cell activation and differentiation
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98 The complement C1s cleaves HMGB1, generating a potent anti-inflammatory product
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166 The complement system is dysregulated in long covid patients
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205 The complex role of complement in hepatocellular carcinoma
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171 The dominant form of the C1 inhibitor R444C variant causing type II hereditary angioedema is its covalent adduct with serum albumin explaining elevated levels
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241 The dynamics of neutrophil intracellular C3 in homeostasis and inflammation
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Nord, Dianna
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79 The functional consequence of two CFI ultra rare variants in complement-mediated diseases: Insights from in vitro splicing assay
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Heinen, Cobey
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115 The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2
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Stravalaci, Matteo
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75 The molecular basis for C1s inhibition by Lyme disease spirochetes
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Thomas, Sheila
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228 The multi-faceted role of complement C3aR in the development and treatment of colorectal cancer
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Krieg, Carsten
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46 The mycobacterial strain-dependent impact of the complement system in tuberculosis
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Villegas, Mario Alejandro Duque
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219 Therapy induced senescence in cancer cell lines affects complement activation and complement regulatory proteins expression
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Abu-Humaidan, Anas
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| 237 |
The role of C5a receptors in autoimmunity
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Schanzenbacher, Jovan
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244 The role of the complement system in DCD liver transplantation
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Mahendran, Balaji
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123 The temporal role of complement in severe trauma and hemorrhagic shock
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Huber-Lang, Markus
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Tissue plasminogen activator receptor ANXA2 and its complementary regulator anti-inflammatory ANXA1 as prognostic indicators of inflammatory response in COVID-19 pathogenesis
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Shenoy, Rathika D.
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TLR-2 agonist Pam3CSK4 has no therapeutic effect on visceral leishmaniasis in BALB/c mice and may enhance the pathogenesis of the disease
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Liao, Xuechun
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TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor
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Gao, Xin
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175 Transposon mutagenesis: A molecular switch in Acinetobacter baumannii for rapid adaptation to bacteriophages and the complement system
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Chen, Carmen
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92 Treatment with warfarin but not Factor Xa inhibitors, is associated with dysregulated, noncanonical, complement activation
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Ekdahl, Kristina N
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66 Tumor-derived complement is required for tumor growth in syngeneic murine STK11-mutant lung adenocarcinoma
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Suzuki, Sora
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82 Using the C3 gain-of-function mouse model of aHUS as a complement therapeutic testbed to enable precision medicine for complement mediated atypical haemolytic uraemic syndrome
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Smith-Jackson, Kate
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188 Vemircopan (ALXN2050) monotherapy in paroxysmal nocturnal hemoglobinuria: Interim data from a phase 2 open-label proof-of-concept study
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Browett, Peter
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161 VIS954 is a Potent Anti-C5aR1 Antibody for the Treatment of ANCA-Associated Vasculitis
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Olinski, Lauren
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153 Visualizing complement activation and regulation in the tumor microenvironment
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van Keulen, Joanne
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XXIX International Complement Workshop Newcastle 2023
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Marchbank, Kevin J.
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