nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Academic HTS: diverse portraits
|
Nelson, Sandra L. |
|
2008 |
32-33 |
1 |
p. e29-e33 nvt p. |
artikel |
2 |
A critical assessment of the potential of short interfering RNA therapeutics
|
Stein, C.A. |
|
2005 |
32-33 |
1 |
p. 27-31 5 p. |
artikel |
3 |
A Drosophila approach to thyroid cancer therapeutics
|
Das, Tirtha K. |
|
2013 |
32-33 |
1 |
p. e65-e71 nvt p. |
artikel |
4 |
All-hydrocarbon stapled peptides as Synthetic Cell-Accessible Mini-Proteins
|
Verdine, Gregory L. |
|
2012 |
32-33 |
1 |
p. e41-e47 nvt p. |
artikel |
5 |
Alzheimer's disease drug discovery: in vivo screening using Caenorhabditis elegans as a model for β-amyloid peptide-induced toxicity
|
Lublin, A.L. |
|
2013 |
32-33 |
1 |
p. e115-e119 nvt p. |
artikel |
6 |
Analysis of complex, multidimensional datasets
|
Girolami, Mark |
|
2006 |
32-33 |
1 |
p. 13-19 7 p. |
artikel |
7 |
Animal models in therapeutic drug discovery for oculopharyngeal muscular dystrophy
|
Chartier, Aymeric |
|
2013 |
32-33 |
1 |
p. e103-e108 nvt p. |
artikel |
8 |
An industrial perspective on positive allosteric modulation as a means to discover safe and selective drugs
|
Rocheville, Magalie |
|
2010 |
32-33 |
1 |
p. e87-e94 nvt p. |
artikel |
9 |
An integrated bioinformatics infrastructure essential for advancing pharmacogenomics and personalized medicine in the context of the FDA's Critical Path Initiative
|
Tong, Weida |
|
2007 |
32-33 |
1 |
p. 3-8 6 p. |
artikel |
10 |
Assessment of drug-induced immunotoxicity in animal models
|
van Wijk, Femke |
|
2006 |
32-33 |
1 |
p. 103-109 7 p. |
artikel |
11 |
Beyond cell penetrating peptides: designed molecular transporters
|
Wender, Paul A. |
|
2012 |
32-33 |
1 |
p. e49-e55 nvt p. |
artikel |
12 |
Biocatalytic synthesis of enantiopure building blocks for pharmaceuticals
|
Simon, Robert C. |
|
2013 |
32-33 |
1 |
p. e37-e44 nvt p. |
artikel |
13 |
Biomarkers for pharmacogenetic and pharmacogenomic studies: Locking down analytical performance
|
Mansfield, Elizabeth |
|
2007 |
32-33 |
1 |
p. 17-20 4 p. |
artikel |
14 |
Biomarkers for pharmacogenetic and pharmacogenomic studies: special issues in analytical performance
|
Mansfield, Elizabeth |
|
2007 |
32-33 |
1 |
p. 21-24 4 p. |
artikel |
15 |
Buccal drug delivery: A challenge already won?
|
Rossi, Silvia |
|
2005 |
32-33 |
1 |
p. 59-65 7 p. |
artikel |
16 |
Catalytic asymmetric alkylation of ketones using organometallic reagents
|
Madduri, Ashoka V.R. |
|
2013 |
32-33 |
1 |
p. e21-e27 nvt p. |
artikel |
17 |
Cell-based assays for kinase drug discovery
|
Smith, Gary K. |
|
2010 |
32-33 |
1 |
p. e13-e19 nvt p. |
artikel |
18 |
Chemical kinomics – a target gene family approach in chemical biology
|
Klebl, Bert M. |
|
2004 |
32-33 |
1 |
p. 25-34 10 p. |
artikel |
19 |
Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders
|
Sarkar, Sovan |
|
2013 |
32-33 |
1 |
p. e137-e144 nvt p. |
artikel |
20 |
Chitosan and the mucosal delivery of biotechnology drugs
|
Issa, Mohamed M. |
|
2005 |
32-33 |
1 |
p. 1-6 6 p. |
artikel |
21 |
Colonic drug delivery
|
Rubinstein, Abraham |
|
2005 |
32-33 |
1 |
p. 33-37 5 p. |
artikel |
22 |
Contents
|
|
|
2008 |
32-33 |
1 |
p. i- 1 p. |
artikel |
23 |
Contents
|
|
|
2006 |
32-33 |
1 |
p. i- 1 p. |
artikel |
24 |
Contents
|
|
|
2005 |
32-33 |
1 |
p. i-ii nvt p. |
artikel |
25 |
Contents
|
|
|
2004 |
32-33 |
1 |
p. i- 1 p. |
artikel |
26 |
Contents
|
|
|
2007 |
32-33 |
1 |
p. i- 1 p. |
artikel |
27 |
Continuous flow synthesis
|
Yoshida, Jun-ichi |
|
2013 |
32-33 |
1 |
p. e53-e59 nvt p. |
artikel |
28 |
Determination of inflammatory biomarkers by immunoaffinity capillary electrophoresis
|
Guzman, Norberto A. |
|
2006 |
32-33 |
1 |
p. 29-37 9 p. |
artikel |
29 |
Discovery and applications of naturally occurring cyclic peptides
|
Thorstholm, L. |
|
2012 |
32-33 |
1 |
p. e13-e21 nvt p. |
artikel |
30 |
Discovery of therapeutic targets by phenotype-based zebrafish screens
|
Peterson, Randall T. |
|
2004 |
32-33 |
1 |
p. 49-54 6 p. |
artikel |
31 |
Display considerations for quantitative radiology
|
Badano, Aldo |
|
2007 |
32-33 |
1 |
p. 29-32 4 p. |
artikel |
32 |
Drug metabolism in silico – the knowledge-based expert system approach. Historical perspectives and current strategies
|
Long, Anthony |
|
2013 |
32-33 |
1 |
p. e147-e153 nvt p. |
artikel |
33 |
Editorial
|
|
|
2006 |
32-33 |
1 |
p. 1-3 3 p. |
artikel |
34 |
Editorial
|
|
|
2005 |
32-33 |
1 |
p. iii-iv nvt p. |
artikel |
35 |
Editorial for HTS revisited
|
Gribbon, Phillip |
|
2008 |
32-33 |
1 |
p. e1- 1 p. |
artikel |
36 |
End-capped α-helices as modulators of protein function
|
Mahon, Andrew B. |
|
2012 |
32-33 |
1 |
p. e57-e62 nvt p. |
artikel |
37 |
Enhancing exposure of protein therapeutics
|
Beals, John M. |
|
2006 |
32-33 |
1 |
p. 87-94 8 p. |
artikel |
38 |
Epigenetic control of the immune system: histone demethylation as a target for drug discovery
|
Lora, Jose M. |
|
2010 |
32-33 |
1 |
p. e67-e75 nvt p. |
artikel |
39 |
Epigenetics: tools and technologies
|
Janzen, William P. |
|
2010 |
32-33 |
1 |
p. e59-e65 nvt p. |
artikel |
40 |
Evolution in thinking and processes?
|
Sewing, Andreas |
|
2008 |
32-33 |
1 |
p. e9-e14 nvt p. |
artikel |
41 |
Exposition and reactivity optimization to predict sites of metabolism in chemicals
|
Cruciani, Gabriele |
|
2013 |
32-33 |
1 |
p. e155-e165 nvt p. |
artikel |
42 |
FDA's Critical Path Initiative
|
Woodcock, Janet |
|
2007 |
32-33 |
1 |
p. 1- 1 p. |
artikel |
43 |
FDA's proactive role in the development of an artificial pancreas for the treatment of diabetes mellitus
|
Pinkos, Arleen |
|
2007 |
32-33 |
1 |
p. 25-28 4 p. |
artikel |
44 |
Fishing for targets: novel approaches using small molecule baits
|
Szardenings, Katrin |
|
2004 |
32-33 |
1 |
p. 9-15 7 p. |
artikel |
45 |
Fixing clearance as early as lead optimization using high throughput in vitro incubations in combination with exact mass detection and automatic structure elucidation of metabolites
|
Zimmerlin, Alfred |
|
2013 |
32-33 |
1 |
p. e191-e198 nvt p. |
artikel |
46 |
Glycomics – a new target for pharmaceuticals
|
Nakano, Miyako |
|
2006 |
32-33 |
1 |
p. 39-47 9 p. |
artikel |
47 |
Gold-catalyzed formation of heterocycles – an enabling new technology for medicinal chemistry
|
Shen, Hong C. |
|
2013 |
32-33 |
1 |
p. e3-e14 nvt p. |
artikel |
48 |
G protein-coupled receptor kinases: Specific phosphorylation of 7TM receptors and beyond
|
Murga, C. |
|
2010 |
32-33 |
1 |
p. e43-e49 nvt p. |
artikel |
49 |
β-Hairpin protein epitope mimetic technology in drug discovery
|
Obrecht, Daniel |
|
2012 |
32-33 |
1 |
p. e63-e69 nvt p. |
artikel |
50 |
High-throughput, computer assisted, specific MetID. A revolution for drug discovery
|
Zamora, Ismael |
|
2013 |
32-33 |
1 |
p. e199-e205 nvt p. |
artikel |
51 |
High-throughput hit finding and compound-profiling technologies for academic drug discovery
|
Gribbon, Philip |
|
2008 |
32-33 |
1 |
p. e3-e7 nvt p. |
artikel |
52 |
Identifying orphan G protein coupled receptors in drug discovery
|
Dunlop, John |
|
2004 |
32-33 |
1 |
p. 61-68 8 p. |
artikel |
53 |
Image-based high-content reporter assays: limitations and advantages
|
Gasparri, Fabio |
|
2010 |
32-33 |
1 |
p. e21-e30 nvt p. |
artikel |
54 |
Inhibition of cytochrome P450 enzymes and biochemical aspects of mechanism-based inactivation (MBI)
|
Kamel, Amin |
|
2013 |
32-33 |
1 |
p. e177-e189 nvt p. |
artikel |
55 |
Innovative methods in drug regulatory sciences
|
Leufkens, Hubert (Bert) G. |
|
2011 |
32-33 |
1 |
p. e1-e2 nvt p. |
artikel |
56 |
In vivo strategies for drug discovery in myotonic dystrophy disorders
|
Garcia-Alcover, Irma |
|
2013 |
32-33 |
1 |
p. e97-e102 nvt p. |
artikel |
57 |
Ion channel screening – automated patch clamp on the rise
|
Farre, Cecilia |
|
2008 |
32-33 |
1 |
p. e23-e28 nvt p. |
artikel |
58 |
Is quantitative benefit–risk modelling of drugs desirable or possible?
|
Phillips, Lawrence D. |
|
2011 |
32-33 |
1 |
p. e3-e10 nvt p. |
artikel |
59 |
Knottins: disulfide-bonded therapeutic and diagnostic peptides
|
Moore, Sarah J. |
|
2012 |
32-33 |
1 |
p. e3-e11 nvt p. |
artikel |
60 |
Label-free receptor assays
|
Fang, Ye |
|
2010 |
32-33 |
1 |
p. e5-e11 nvt p. |
artikel |
61 |
Mass spectrometric analysis of intact macromolecular chaperone complexes
|
van Duijn, Esther |
|
2006 |
32-33 |
1 |
p. 21-27 7 p. |
artikel |
62 |
Mass spectrometry techniques for qualitative and quantitative analysis of biomarkers
|
Drexler, Dieter M. |
|
2004 |
32-33 |
1 |
p. 17-23 7 p. |
artikel |
63 |
Mechanistic pharmacology, new developments
|
Wise, Alan |
|
2010 |
32-33 |
1 |
p. e1-e3 nvt p. |
artikel |
64 |
Metabolites: structure determination and prediction
|
Cruciani, Gabriele |
|
2013 |
32-33 |
1 |
p. e145-e146 nvt p. |
artikel |
65 |
Metabolomic biomarkers: their role in the critical path
|
Schnackenberg, Laura K. |
|
2007 |
32-33 |
1 |
p. 13-16 4 p. |
artikel |
66 |
Metal-free bioconjugation reactions
|
van Berkel, Sander S. |
|
2013 |
32-33 |
1 |
p. e45-e51 nvt p. |
artikel |
67 |
Miniaturization: Chip-based liquid chromatography and proteomics
|
Gauthier, Georges L. |
|
2006 |
32-33 |
1 |
p. 59-66 8 p. |
artikel |
68 |
Modeling colorectal cancer as a 3-dimensional disease in a dish: the case for drug screening using organoids, zebrafish, and fruit flies
|
Markstein, Michele |
|
2013 |
32-33 |
1 |
p. e73-e81 nvt p. |
artikel |
69 |
Modelling cytochromes P450 binding modes to predict P450 inhibition, metabolic stability and isoform selectivity
|
Carosati, Emanuele |
|
2013 |
32-33 |
1 |
p. e167-e175 nvt p. |
artikel |
70 |
Model organisms and target discovery
|
Muda, Marco |
|
2004 |
32-33 |
1 |
p. 55-59 5 p. |
artikel |
71 |
Model organisms offer new possibilities for discovery of therapeutics
|
Draper, Isabelle |
|
2013 |
32-33 |
1 |
p. e61-e64 nvt p. |
artikel |
72 |
Modern analytical technologies for the detection of drug abuse and doping
|
Huestis, Marilyn A. |
|
2006 |
32-33 |
1 |
p. 49-57 9 p. |
artikel |
73 |
Molecular imprinting: A new tool for drug innovation
|
van Nostrum, Cornelus F. |
|
2005 |
32-33 |
1 |
p. 119-124 6 p. |
artikel |
74 |
Molecular motors as drug delivery vehicles
|
Cohen, Richard N. |
|
2005 |
32-33 |
1 |
p. 111-118 8 p. |
artikel |
75 |
Mucoadhesive systems in oral drug delivery
|
Bernkop-Schnürch, Andreas |
|
2005 |
32-33 |
1 |
p. 83-87 5 p. |
artikel |
76 |
Multicomponent reactions – opportunities for the pharmaceutical industry
|
Ruijter, Eelco |
|
2013 |
32-33 |
1 |
p. e15-e20 nvt p. |
artikel |
77 |
Nanoparticle uptake by the oral route: Fulfilling its potential?
|
Florence, Alexander T. |
|
2005 |
32-33 |
1 |
p. 75-81 7 p. |
artikel |
78 |
New approaches to strengthen pharmacovigilance
|
Arlett, Peter R. |
|
2011 |
32-33 |
1 |
p. e15-e19 nvt p. |
artikel |
79 |
New poly(lactic-co-glycolic acid) derivatives: Modular polymers with tailored properties
|
Dailey, Lea Ann |
|
2005 |
32-33 |
1 |
p. 7-13 7 p. |
artikel |
80 |
New synthetic technologies
|
Rutjes, Floris |
|
2013 |
32-33 |
1 |
p. e1-e2 nvt p. |
artikel |
81 |
New technologies for assessing UDP-glucuronosyltransferase (UGT) metabolism in drug discovery and development
|
Patten, Christopher J. |
|
2006 |
32-33 |
1 |
p. 73-78 6 p. |
artikel |
82 |
Nonviral gene delivery systems: From simple transfection agents to artificial viruses
|
Mastrobattista, Enrico |
|
2005 |
32-33 |
1 |
p. 103-109 7 p. |
artikel |
83 |
Novel biomarker platforms in toxicology
|
Shaw, Martin |
|
2006 |
32-33 |
1 |
p. 95-102 8 p. |
artikel |
84 |
On the edge of new technologies (advanced therapies, nanomedicines)
|
Vamvakas, Spiros |
|
2011 |
32-33 |
1 |
p. e21-e28 nvt p. |
artikel |
85 |
Opioid peptides: potential for drug development
|
Aldrich, Jane V. |
|
2012 |
32-33 |
1 |
p. e23-e31 nvt p. |
artikel |
86 |
Organocatalytic methods for CC bond formation
|
Mahrwald, Rainer |
|
2013 |
32-33 |
1 |
p. e29-e36 nvt p. |
artikel |
87 |
Patient opinions and preferences in drug development and regulatory decision making
|
Breckenridge, Alasdair |
|
2011 |
32-33 |
1 |
p. e11-e14 nvt p. |
artikel |
88 |
Pepducins: lipopeptide allosteric modulators of GPCR signaling
|
Carlson, Kenneth E. |
|
2012 |
32-33 |
1 |
p. e33-e39 nvt p. |
artikel |
89 |
Peptides or modified peptides as drug molecules
|
Carney, S.L. |
|
2012 |
32-33 |
1 |
p. e1-e2 nvt p. |
artikel |
90 |
Performance-driven, pulmonary delivery of systemically acting drugs
|
Vanbever, Rita |
|
2005 |
32-33 |
1 |
p. 39-46 8 p. |
artikel |
91 |
Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease
|
Tardiff, Daniel F. |
|
2013 |
32-33 |
1 |
p. e121-e128 nvt p. |
artikel |
92 |
Physiology-based pharmacokinetic modeling: ready to be used
|
Schmitt, Walter |
|
2005 |
32-33 |
1 |
p. 125-132 8 p. |
artikel |
93 |
Population genetics for target identification
|
Healy, Daniel G. |
|
2004 |
32-33 |
1 |
p. 69-74 6 p. |
artikel |
94 |
Post-innovation innovation of medicinal products
|
Leufkens, Hubert (Bert) G. |
|
2011 |
32-33 |
1 |
p. e37-e41 nvt p. |
artikel |
95 |
Proteomics: how to control highly dynamic patterns of millions of molecules and interpret changes correctly?
|
Schrattenholz, André |
|
2004 |
32-33 |
1 |
p. 1-8 8 p. |
artikel |
96 |
Questions and answers about the Pilot Process for Biomarker Qualification at the FDA
|
Goodsaid, Federico M. |
|
2007 |
32-33 |
1 |
p. 9-11 3 p. |
artikel |
97 |
Rationale and benefit of using high throughput solubility screens in drug discovery
|
Goodwin, Joseph J. |
|
2006 |
32-33 |
1 |
p. 67-71 5 p. |
artikel |
98 |
Recent applications of protein arrays in target identification and disease monitoring
|
Witte, Krista L. |
|
2004 |
32-33 |
1 |
p. 35-40 6 p. |
artikel |
99 |
Seeking ligand bias: assessing GPCR coupling to β-arrestins for drug discovery
|
Bohn, Laura M. |
|
2010 |
32-33 |
1 |
p. e37-e42 nvt p. |
artikel |
100 |
Shaping biodegradable polymers as nanostructures: Fabrication and applications
|
Lu, Yi |
|
2005 |
32-33 |
1 |
p. 97-102 6 p. |
artikel |
101 |
Smart polymeric micelles for gene and drug delivery
|
Nishiyama, Nobuhiro |
|
2005 |
32-33 |
1 |
p. 21-26 6 p. |
artikel |
102 |
Software aided approaches to structure-based metabolite identification in drug discovery and development
|
Pähler, Axel |
|
2013 |
32-33 |
1 |
p. e207-e217 nvt p. |
artikel |
103 |
Soluble polymer conjugates for drug delivery
|
Minko, Tamara |
|
2005 |
32-33 |
1 |
p. 15-20 6 p. |
artikel |
104 |
Stem cells, immortalized cells and primary cells in ADMET assays
|
Sinz, Michael W. |
|
2006 |
32-33 |
1 |
p. 79-85 7 p. |
artikel |
105 |
Subcutaneous drug delivery and the role of the lymphatics
|
McLennan, Danielle N. |
|
2005 |
32-33 |
1 |
p. 89-96 8 p. |
artikel |
106 |
The impact of physical based methods screening and their delivery of better quality hits
|
Kahmann, Jan |
|
2008 |
32-33 |
1 |
p. e15-e22 nvt p. |
artikel |
107 |
The use of affinity sorbents in targeted proteomics
|
Freije, J. Robert |
|
2006 |
32-33 |
1 |
p. 5-11 7 p. |
artikel |
108 |
Tissue microarrays for early target evaluation
|
Simon, Ronald |
|
2004 |
32-33 |
1 |
p. 41-48 8 p. |
artikel |
109 |
Trends in the technology-driven development of new inhalation devices
|
Frijlink, Henderik W. |
|
2005 |
32-33 |
1 |
p. 47-57 11 p. |
artikel |
110 |
Uncovering GPCR heteromer-biased ligands
|
Mustafa, Sanam |
|
2010 |
32-33 |
1 |
p. e77-e85 nvt p. |
artikel |
111 |
Use of functional assays to detect and quantify functional selectivity
|
Clarke, William P. |
|
2010 |
32-33 |
1 |
p. e31-e36 nvt p. |
artikel |
112 |
Use of small RNAs for therapeutic gene silencing: risk versus benefit
|
Börner, Kathleen |
|
2010 |
32-33 |
1 |
p. e51-e57 nvt p. |
artikel |
113 |
Using Drosophila as a tool to identify pharmacological therapies for fragile X syndrome
|
McBride, Sean M.J. |
|
2013 |
32-33 |
1 |
p. e129-e136 nvt p. |
artikel |
114 |
Vesicles as a tool for transdermal and dermal delivery
|
Honeywell-Nguyen, P. Loan |
|
2005 |
32-33 |
1 |
p. 67-74 8 p. |
artikel |
115 |
Weighing benefit–risk of medicines: concepts and approaches
|
Mt-Isa, Shahrul |
|
2011 |
32-33 |
1 |
p. e29-e35 nvt p. |
artikel |
116 |
Zebrafish-based small molecule screens for novel cardiovascular drugs
|
Novodvorsky, Peter |
|
2013 |
32-33 |
1 |
p. e109-e114 nvt p. |
artikel |
117 |
Zebrafish based small molecule screens for novel DMD drugs
|
Kawahara, Genri |
|
2013 |
32-33 |
1 |
p. e91-e96 nvt p. |
artikel |
118 |
Zebrafish cancer and metastasis models for in vivo drug discovery
|
Tat, Jennifer |
|
2013 |
32-33 |
1 |
p. e83-e89 nvt p. |
artikel |