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                             82 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Advances and perspectives in human and mouse embryonic stem cell bioprocessing Oh, Steve K.W.
2008
21-22 4 p. e125-e130
nvt p.
artikel
2 Advances in screening for membrane permeability: high-resolution PAMPA for medicinal chemists Kansy, Manfred
2004
21-22 4 p. 349-355
7 p.
artikel
3 Advances in virtual screening Muegge, Ingo
2006
21-22 4 p. 405-411
7 p.
artikel
4 Approaches to Scaffold Hopping Lloyd, David G.
2013
21-22 4 p. e451-e452
nvt p.
artikel
5 Automation and robotics in ADME screening Saunders, Kenneth C.
2004
21-22 4 p. 373-380
8 p.
artikel
6 Building in molecular diversity for targeted libraries Sheppard, David W.
2013
21-22 4 p. e461-e466
nvt p.
artikel
7 Caco-2 replace or refine? Ungell, Anna-Lena B.
2004
21-22 4 p. 423-430
8 p.
artikel
8 Chemical diversity and biological activity Schuffenhauer, Ansgar
2006
21-22 4 p. 387-395
9 p.
artikel
9 Cheminformatics and drug discovery Oprea, Tudor I.
2006
21-22 4 p. 355-356
2 p.
artikel
10 Computational prediction of drug toxicity: the case of mutagenicity and carcinogenicity Benigni, Romualdo
2004
21-22 4 p. 457-463
7 p.
artikel
11 Conformations and 3D pharmacophore searching Schwab, Christof H.
2010
21-22 4 p. e245-e253
nvt p.
artikel
12 Contents 2004
21-22 4 p. i-
1 p.
artikel
13 Contents 2005
21-22 4 p. i-
1 p.
artikel
14 Contents 2008
21-22 4 p. i-
1 p.
artikel
15 C(X)CR in silico: Computer-aided prediction of chemokine receptor–ligand interactions Roumen, L.
2012
21-22 4 p. e281-e291
nvt p.
artikel
16 De novo design – hop(p)ing against hope Schneider, Gisbert
2013
21-22 4 p. e453-e460
nvt p.
artikel
17 De-peptidising protein–protein interactions – big jobs for small molecules Fayne, Darren
2013
21-22 4 p. e467-e474
nvt p.
artikel
18 Derivation, maintenance and cryostorage of human embryonic stem cells Holm, Frida
2008
21-22 4 p. e131-e137
nvt p.
artikel
19 Docking compared to 3D-pharmacophores: the scoring function challenge Hein, Michael
2010
21-22 4 p. e229-e236
nvt p.
artikel
20 3D pharmacophore elucidation and virtual screening Wolber, Gerhard
2010
21-22 4 p. e203-e204
nvt p.
artikel
21 3D pharmacophores as tools for activity profiling Schuster, Daniela
2010
21-22 4 p. e205-e211
nvt p.
artikel
22 Editorial 2005
21-22 4 p. 303-304
2 p.
artikel
23 Epigenetic remodeling and stem cells Altun, Gulsah
2008
21-22 4 p. e139-e142
nvt p.
artikel
24 Focused chemistry from annotated libraries Balakin, Konstantin V.
2006
21-22 4 p. 397-403
7 p.
artikel
25 ‘Fuzziness’ in pharmacophore-based virtual screening and de novo design Klenner, Alexander
2010
21-22 4 p. e237-e244
nvt p.
artikel
26 Grid-derived structure-based 3D pharmacophores and their performance compared to docking Cross, Simon
2010
21-22 4 p. e213-e219
nvt p.
artikel
27 High throughput protein crystallography: Developments in crystallisation, data collection and data processing O’Reilly, Marc
2006
21-22 4 p. 451-456
6 p.
artikel
28 History of 3D pharmacophore searching: commercial, academic and open-source tools Van Drie, John H.
2010
21-22 4 p. e255-e262
nvt p.
artikel
29 Hit and lead identification: Integrated technology-based approaches Goodnow Jr, Robert A.
2006
21-22 4 p. 367-375
9 p.
artikel
30 Imaging approaches for monitoring chemotherapy Bacharach, Stephen L.
2005
21-22 4 p. 329-334
6 p.
artikel
31 Imaging studies for evaluating gene therapy in translational research Peñuelas, Iván
2005
21-22 4 p. 335-343
9 p.
artikel
32 Imaging studies in drug development: Parkinson's disease Brooks, David J.
2005
21-22 4 p. 317-321
5 p.
artikel
33 Imaging technologies in drug development: Anxiety and depression Rabiner, Eugenii A.
2005
21-22 4 p. 323-327
5 p.
artikel
34 Information systems for surrogate biomarkers Hehenberger, Michael
2005
21-22 4 p. 369-373
5 p.
artikel
35 Inhibition of PDZ domain-mediated interactions Grillo-Bosch, Dolors
2013
21-22 4 p. e531-e540
nvt p.
artikel
36 Inhibitors of protein–protein interactions: New methodologies to tackle this challenge Silvian, Laura
2013
21-22 4 p. e509-e515
nvt p.
artikel
37 In silico prediction of drug safety: despite progress there is abundant room for improvement Egan, William J.
2004
21-22 4 p. 381-387
7 p.
artikel
38 ‘In silico’ simulations to assess the ‘in vivo’ consequences of ‘in vitro’ metabolic drug–drug interactions Rostami-Hodjegan, Amin
2004
21-22 4 p. 441-448
8 p.
artikel
39 In silico target fishing: Predicting biological targets from chemical structure Jenkins, Jeremy L.
2006
21-22 4 p. 413-421
9 p.
artikel
40 Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects Fehniger, Thomas E.
2005
21-22 4 p. 345-351
7 p.
artikel
41 Integration of virtual and physical screening Fara, Dan C.
2006
21-22 4 p. 377-385
9 p.
artikel
42 Intestinal and blood–brain drug transport: beyond involvement of a single transport function Lennernäs, Hans
2004
21-22 4 p. 417-422
6 p.
artikel
43 Lead- and drug-like compounds: the rule-of-five revolution Lipinski, Christopher A.
2004
21-22 4 p. 337-341
5 p.
artikel
44 Lipophilicity – beyond octanol/water: a short comparison of modern technologies Hartmann, Thorsten
2004
21-22 4 p. 431-439
9 p.
artikel
45 Livers cells derived from human embryonic stem cells Andersson, Tommy B.
2008
21-22 4 p. e143-e147
nvt p.
artikel
46 Mass spectrometry-based methods for biomarker detection and analysis von Neuhoff, Nils
2005
21-22 4 p. 361-367
7 p.
artikel
47 Metabolic screening in vitro: metabolic stability, CYP inhibition and induction Riley, Robert J.
2004
21-22 4 p. 365-372
8 p.
artikel
48 Molecular crime scene investigation – dusting for fingerprints Bajorath, Jürgen
2013
21-22 4 p. e491-e498
nvt p.
artikel
49 Molecular topology – dissimilar similarities Galvez, Jorge
2013
21-22 4 p. e475-e481
nvt p.
artikel
50 NMR in the analysis of functional chemokine interactions and drug discovery Ziarek, Joshua J.
2012
21-22 4 p. e293-e299
nvt p.
artikel
51 Peptidylarginine deiminases: physiological function, interaction with chemokines and role in pathology Moelants, Eva A.V.
2012
21-22 4 p. e261-e280
nvt p.
artikel
52 PET studies in drug development: Methodological considerations Cunningham, Vincent J.
2005
21-22 4 p. 311-315
5 p.
artikel
53 Physicochemical profiling: overview of the screens Kerns, E.H.
2004
21-22 4 p. 343-348
6 p.
artikel
54 Physiology-based pharmacokinetic modeling: ready to be used Schmitt, Walter
2004
21-22 4 p. 449-456
8 p.
artikel
55 Predicting the intestinal absorption potential of hits and leads Hämäläinen, M.D.
2004
21-22 4 p. 397-405
9 p.
artikel
56 Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models Abbott, N. Joan
2004
21-22 4 p. 407-416
10 p.
artikel
57 Prediction of human clearance (CL) and volume of distribution (VD) Keldenich, Jörg
2004
21-22 4 p. 389-395
7 p.
artikel
58 Probing structural adaptivity at PPI interfaces with small molecules Wilson, Christopher G.
2013
21-22 4 p. e501-e508
nvt p.
artikel
59 Protein pathway analysis in Clinical Proteomics using protein microarrays Geho, David H.
2005
21-22 4 p. 353-359
7 p.
artikel
60 Proteomic approaches in drug discovery Veenstra, Timothy D.
2006
21-22 4 p. 433-440
8 p.
artikel
61 Proteomics in antitumor research Fontana, Simona
2006
21-22 4 p. 441-449
9 p.
artikel
62 Rational design of LEDGINs as first allosteric integrase inhibitors for the treatment of HIV infection Desimmie, Belete A.
2013
21-22 4 p. e517-e522
nvt p.
artikel
63 Scaffold variations in amine warhead of histamine H3 receptor antagonists Wingen, Kerstin
2013
21-22 4 p. e483-e489
nvt p.
artikel
64 Screening for the role of transporters in hepatic and renal drug handling Masereeuw, Rosalinde
2004
21-22 4 p. 357-364
8 p.
artikel
65 Small molecule inhibitors of the HIV-1 virulence factor, Nef Smithgall, Thomas E.
2013
21-22 4 p. e523-e529
nvt p.
artikel
66 Small-molecule modulation of protein–protein interactions Ottmann, Christian
2013
21-22 4 p. e499-e500
nvt p.
artikel
67 Small molecules modulation of 14-3-3 protein–protein interactions Mori, Mattia
2013
21-22 4 p. e541-e547
nvt p.
artikel
68 Stem cell reprogramming: generation of patient-specific stem cells by somatic cell nuclear reprogramming Simonsson, Stina
2008
21-22 4 p. e117-e124
nvt p.
artikel
69 Stem cells Carney, Steve L.
2008
21-22 4 p. e105-e106
nvt p.
artikel
70 Strategies for 3D pharmacophore-based virtual screening Seidel, Thomas
2010
21-22 4 p. e221-e228
nvt p.
artikel
71 Target, chemical and bioactivity databases – integration is key Oprea, Tudor I.
2006
21-22 4 p. 357-365
9 p.
artikel
72 Targeting chemokine–glycan interactions: the CellJammer® technology platform Trinker, Martin U.
2012
21-22 4 p. e253-e259
nvt p.
artikel
73 Targeting chemokines and chemokine receptors with antibodies Klarenbeek, Alex
2012
21-22 4 p. e237-e244
nvt p.
artikel
74 Targeting the chemokine receptor system Smit, Martine J.
2012
21-22 4 p. e227-e228
nvt p.
artikel
75 Techniques for rational design Kubinyi, Hugo
2006
21-22 4 p. 423-424
2 p.
artikel
76 The enabling technologies needed for PET-based molecular imaging to support drug development Jones, Terry
2005
21-22 4 p. 305-309
5 p.
artikel
77 The fragment-approach: An update Bartoli, Sandra
2006
21-22 4 p. 425-431
7 p.
artikel
78 Therapeutic targeting of chemokine receptors by small molecules Wijtmans, Maikel
2012
21-22 4 p. e229-e236
nvt p.
artikel
79 The scaffold hopping potential of pharmacophores Hessler, Gerhard
2010
21-22 4 p. e263-e269
nvt p.
artikel
80 Unnatural amino acids for the study of chemokine receptor structure and dynamics Siderius, Marco
2012
21-22 4 p. e301-e313
nvt p.
artikel
81 Viral and non-viral gene delivery and its role in pluripotent stem cell engineering Kane, Nicole M.
2008
21-22 4 p. e107-e115
nvt p.
artikel
82 Why and how to find neutraligands targeting chemokines? Galzi, Jean-Luc
2012
21-22 4 p. e245-e251
nvt p.
artikel
                             82 gevonden resultaten
 
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