nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Advances and perspectives in human and mouse embryonic stem cell bioprocessing
|
Oh, Steve K.W. |
|
2008 |
21-22 |
4 |
p. e125-e130 nvt p. |
artikel |
2 |
Advances in screening for membrane permeability: high-resolution PAMPA for medicinal chemists
|
Kansy, Manfred |
|
2004 |
21-22 |
4 |
p. 349-355 7 p. |
artikel |
3 |
Advances in virtual screening
|
Muegge, Ingo |
|
2006 |
21-22 |
4 |
p. 405-411 7 p. |
artikel |
4 |
Approaches to Scaffold Hopping
|
Lloyd, David G. |
|
2013 |
21-22 |
4 |
p. e451-e452 nvt p. |
artikel |
5 |
Automation and robotics in ADME screening
|
Saunders, Kenneth C. |
|
2004 |
21-22 |
4 |
p. 373-380 8 p. |
artikel |
6 |
Building in molecular diversity for targeted libraries
|
Sheppard, David W. |
|
2013 |
21-22 |
4 |
p. e461-e466 nvt p. |
artikel |
7 |
Caco-2 replace or refine?
|
Ungell, Anna-Lena B. |
|
2004 |
21-22 |
4 |
p. 423-430 8 p. |
artikel |
8 |
Chemical diversity and biological activity
|
Schuffenhauer, Ansgar |
|
2006 |
21-22 |
4 |
p. 387-395 9 p. |
artikel |
9 |
Cheminformatics and drug discovery
|
Oprea, Tudor I. |
|
2006 |
21-22 |
4 |
p. 355-356 2 p. |
artikel |
10 |
Computational prediction of drug toxicity: the case of mutagenicity and carcinogenicity
|
Benigni, Romualdo |
|
2004 |
21-22 |
4 |
p. 457-463 7 p. |
artikel |
11 |
Conformations and 3D pharmacophore searching
|
Schwab, Christof H. |
|
2010 |
21-22 |
4 |
p. e245-e253 nvt p. |
artikel |
12 |
Contents
|
|
|
2004 |
21-22 |
4 |
p. i- 1 p. |
artikel |
13 |
Contents
|
|
|
2005 |
21-22 |
4 |
p. i- 1 p. |
artikel |
14 |
Contents
|
|
|
2008 |
21-22 |
4 |
p. i- 1 p. |
artikel |
15 |
C(X)CR in silico: Computer-aided prediction of chemokine receptor–ligand interactions
|
Roumen, L. |
|
2012 |
21-22 |
4 |
p. e281-e291 nvt p. |
artikel |
16 |
De novo design – hop(p)ing against hope
|
Schneider, Gisbert |
|
2013 |
21-22 |
4 |
p. e453-e460 nvt p. |
artikel |
17 |
De-peptidising protein–protein interactions – big jobs for small molecules
|
Fayne, Darren |
|
2013 |
21-22 |
4 |
p. e467-e474 nvt p. |
artikel |
18 |
Derivation, maintenance and cryostorage of human embryonic stem cells
|
Holm, Frida |
|
2008 |
21-22 |
4 |
p. e131-e137 nvt p. |
artikel |
19 |
Docking compared to 3D-pharmacophores: the scoring function challenge
|
Hein, Michael |
|
2010 |
21-22 |
4 |
p. e229-e236 nvt p. |
artikel |
20 |
3D pharmacophore elucidation and virtual screening
|
Wolber, Gerhard |
|
2010 |
21-22 |
4 |
p. e203-e204 nvt p. |
artikel |
21 |
3D pharmacophores as tools for activity profiling
|
Schuster, Daniela |
|
2010 |
21-22 |
4 |
p. e205-e211 nvt p. |
artikel |
22 |
Editorial
|
|
|
2005 |
21-22 |
4 |
p. 303-304 2 p. |
artikel |
23 |
Epigenetic remodeling and stem cells
|
Altun, Gulsah |
|
2008 |
21-22 |
4 |
p. e139-e142 nvt p. |
artikel |
24 |
Focused chemistry from annotated libraries
|
Balakin, Konstantin V. |
|
2006 |
21-22 |
4 |
p. 397-403 7 p. |
artikel |
25 |
‘Fuzziness’ in pharmacophore-based virtual screening and de novo design
|
Klenner, Alexander |
|
2010 |
21-22 |
4 |
p. e237-e244 nvt p. |
artikel |
26 |
Grid-derived structure-based 3D pharmacophores and their performance compared to docking
|
Cross, Simon |
|
2010 |
21-22 |
4 |
p. e213-e219 nvt p. |
artikel |
27 |
High throughput protein crystallography: Developments in crystallisation, data collection and data processing
|
O’Reilly, Marc |
|
2006 |
21-22 |
4 |
p. 451-456 6 p. |
artikel |
28 |
History of 3D pharmacophore searching: commercial, academic and open-source tools
|
Van Drie, John H. |
|
2010 |
21-22 |
4 |
p. e255-e262 nvt p. |
artikel |
29 |
Hit and lead identification: Integrated technology-based approaches
|
Goodnow Jr, Robert A. |
|
2006 |
21-22 |
4 |
p. 367-375 9 p. |
artikel |
30 |
Imaging approaches for monitoring chemotherapy
|
Bacharach, Stephen L. |
|
2005 |
21-22 |
4 |
p. 329-334 6 p. |
artikel |
31 |
Imaging studies for evaluating gene therapy in translational research
|
Peñuelas, Iván |
|
2005 |
21-22 |
4 |
p. 335-343 9 p. |
artikel |
32 |
Imaging studies in drug development: Parkinson's disease
|
Brooks, David J. |
|
2005 |
21-22 |
4 |
p. 317-321 5 p. |
artikel |
33 |
Imaging technologies in drug development: Anxiety and depression
|
Rabiner, Eugenii A. |
|
2005 |
21-22 |
4 |
p. 323-327 5 p. |
artikel |
34 |
Information systems for surrogate biomarkers
|
Hehenberger, Michael |
|
2005 |
21-22 |
4 |
p. 369-373 5 p. |
artikel |
35 |
Inhibition of PDZ domain-mediated interactions
|
Grillo-Bosch, Dolors |
|
2013 |
21-22 |
4 |
p. e531-e540 nvt p. |
artikel |
36 |
Inhibitors of protein–protein interactions: New methodologies to tackle this challenge
|
Silvian, Laura |
|
2013 |
21-22 |
4 |
p. e509-e515 nvt p. |
artikel |
37 |
In silico prediction of drug safety: despite progress there is abundant room for improvement
|
Egan, William J. |
|
2004 |
21-22 |
4 |
p. 381-387 7 p. |
artikel |
38 |
‘In silico’ simulations to assess the ‘in vivo’ consequences of ‘in vitro’ metabolic drug–drug interactions
|
Rostami-Hodjegan, Amin |
|
2004 |
21-22 |
4 |
p. 441-448 8 p. |
artikel |
39 |
In silico target fishing: Predicting biological targets from chemical structure
|
Jenkins, Jeremy L. |
|
2006 |
21-22 |
4 |
p. 413-421 9 p. |
artikel |
40 |
Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects
|
Fehniger, Thomas E. |
|
2005 |
21-22 |
4 |
p. 345-351 7 p. |
artikel |
41 |
Integration of virtual and physical screening
|
Fara, Dan C. |
|
2006 |
21-22 |
4 |
p. 377-385 9 p. |
artikel |
42 |
Intestinal and blood–brain drug transport: beyond involvement of a single transport function
|
Lennernäs, Hans |
|
2004 |
21-22 |
4 |
p. 417-422 6 p. |
artikel |
43 |
Lead- and drug-like compounds: the rule-of-five revolution
|
Lipinski, Christopher A. |
|
2004 |
21-22 |
4 |
p. 337-341 5 p. |
artikel |
44 |
Lipophilicity – beyond octanol/water: a short comparison of modern technologies
|
Hartmann, Thorsten |
|
2004 |
21-22 |
4 |
p. 431-439 9 p. |
artikel |
45 |
Livers cells derived from human embryonic stem cells
|
Andersson, Tommy B. |
|
2008 |
21-22 |
4 |
p. e143-e147 nvt p. |
artikel |
46 |
Mass spectrometry-based methods for biomarker detection and analysis
|
von Neuhoff, Nils |
|
2005 |
21-22 |
4 |
p. 361-367 7 p. |
artikel |
47 |
Metabolic screening in vitro: metabolic stability, CYP inhibition and induction
|
Riley, Robert J. |
|
2004 |
21-22 |
4 |
p. 365-372 8 p. |
artikel |
48 |
Molecular crime scene investigation – dusting for fingerprints
|
Bajorath, Jürgen |
|
2013 |
21-22 |
4 |
p. e491-e498 nvt p. |
artikel |
49 |
Molecular topology – dissimilar similarities
|
Galvez, Jorge |
|
2013 |
21-22 |
4 |
p. e475-e481 nvt p. |
artikel |
50 |
NMR in the analysis of functional chemokine interactions and drug discovery
|
Ziarek, Joshua J. |
|
2012 |
21-22 |
4 |
p. e293-e299 nvt p. |
artikel |
51 |
Peptidylarginine deiminases: physiological function, interaction with chemokines and role in pathology
|
Moelants, Eva A.V. |
|
2012 |
21-22 |
4 |
p. e261-e280 nvt p. |
artikel |
52 |
PET studies in drug development: Methodological considerations
|
Cunningham, Vincent J. |
|
2005 |
21-22 |
4 |
p. 311-315 5 p. |
artikel |
53 |
Physicochemical profiling: overview of the screens
|
Kerns, E.H. |
|
2004 |
21-22 |
4 |
p. 343-348 6 p. |
artikel |
54 |
Physiology-based pharmacokinetic modeling: ready to be used
|
Schmitt, Walter |
|
2004 |
21-22 |
4 |
p. 449-456 8 p. |
artikel |
55 |
Predicting the intestinal absorption potential of hits and leads
|
Hämäläinen, M.D. |
|
2004 |
21-22 |
4 |
p. 397-405 9 p. |
artikel |
56 |
Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models
|
Abbott, N. Joan |
|
2004 |
21-22 |
4 |
p. 407-416 10 p. |
artikel |
57 |
Prediction of human clearance (CL) and volume of distribution (VD)
|
Keldenich, Jörg |
|
2004 |
21-22 |
4 |
p. 389-395 7 p. |
artikel |
58 |
Probing structural adaptivity at PPI interfaces with small molecules
|
Wilson, Christopher G. |
|
2013 |
21-22 |
4 |
p. e501-e508 nvt p. |
artikel |
59 |
Protein pathway analysis in Clinical Proteomics using protein microarrays
|
Geho, David H. |
|
2005 |
21-22 |
4 |
p. 353-359 7 p. |
artikel |
60 |
Proteomic approaches in drug discovery
|
Veenstra, Timothy D. |
|
2006 |
21-22 |
4 |
p. 433-440 8 p. |
artikel |
61 |
Proteomics in antitumor research
|
Fontana, Simona |
|
2006 |
21-22 |
4 |
p. 441-449 9 p. |
artikel |
62 |
Rational design of LEDGINs as first allosteric integrase inhibitors for the treatment of HIV infection
|
Desimmie, Belete A. |
|
2013 |
21-22 |
4 |
p. e517-e522 nvt p. |
artikel |
63 |
Scaffold variations in amine warhead of histamine H3 receptor antagonists
|
Wingen, Kerstin |
|
2013 |
21-22 |
4 |
p. e483-e489 nvt p. |
artikel |
64 |
Screening for the role of transporters in hepatic and renal drug handling
|
Masereeuw, Rosalinde |
|
2004 |
21-22 |
4 |
p. 357-364 8 p. |
artikel |
65 |
Small molecule inhibitors of the HIV-1 virulence factor, Nef
|
Smithgall, Thomas E. |
|
2013 |
21-22 |
4 |
p. e523-e529 nvt p. |
artikel |
66 |
Small-molecule modulation of protein–protein interactions
|
Ottmann, Christian |
|
2013 |
21-22 |
4 |
p. e499-e500 nvt p. |
artikel |
67 |
Small molecules modulation of 14-3-3 protein–protein interactions
|
Mori, Mattia |
|
2013 |
21-22 |
4 |
p. e541-e547 nvt p. |
artikel |
68 |
Stem cell reprogramming: generation of patient-specific stem cells by somatic cell nuclear reprogramming
|
Simonsson, Stina |
|
2008 |
21-22 |
4 |
p. e117-e124 nvt p. |
artikel |
69 |
Stem cells
|
Carney, Steve L. |
|
2008 |
21-22 |
4 |
p. e105-e106 nvt p. |
artikel |
70 |
Strategies for 3D pharmacophore-based virtual screening
|
Seidel, Thomas |
|
2010 |
21-22 |
4 |
p. e221-e228 nvt p. |
artikel |
71 |
Target, chemical and bioactivity databases – integration is key
|
Oprea, Tudor I. |
|
2006 |
21-22 |
4 |
p. 357-365 9 p. |
artikel |
72 |
Targeting chemokine–glycan interactions: the CellJammer® technology platform
|
Trinker, Martin U. |
|
2012 |
21-22 |
4 |
p. e253-e259 nvt p. |
artikel |
73 |
Targeting chemokines and chemokine receptors with antibodies
|
Klarenbeek, Alex |
|
2012 |
21-22 |
4 |
p. e237-e244 nvt p. |
artikel |
74 |
Targeting the chemokine receptor system
|
Smit, Martine J. |
|
2012 |
21-22 |
4 |
p. e227-e228 nvt p. |
artikel |
75 |
Techniques for rational design
|
Kubinyi, Hugo |
|
2006 |
21-22 |
4 |
p. 423-424 2 p. |
artikel |
76 |
The enabling technologies needed for PET-based molecular imaging to support drug development
|
Jones, Terry |
|
2005 |
21-22 |
4 |
p. 305-309 5 p. |
artikel |
77 |
The fragment-approach: An update
|
Bartoli, Sandra |
|
2006 |
21-22 |
4 |
p. 425-431 7 p. |
artikel |
78 |
Therapeutic targeting of chemokine receptors by small molecules
|
Wijtmans, Maikel |
|
2012 |
21-22 |
4 |
p. e229-e236 nvt p. |
artikel |
79 |
The scaffold hopping potential of pharmacophores
|
Hessler, Gerhard |
|
2010 |
21-22 |
4 |
p. e263-e269 nvt p. |
artikel |
80 |
Unnatural amino acids for the study of chemokine receptor structure and dynamics
|
Siderius, Marco |
|
2012 |
21-22 |
4 |
p. e301-e313 nvt p. |
artikel |
81 |
Viral and non-viral gene delivery and its role in pluripotent stem cell engineering
|
Kane, Nicole M. |
|
2008 |
21-22 |
4 |
p. e107-e115 nvt p. |
artikel |
82 |
Why and how to find neutraligands targeting chemokines?
|
Galzi, Jean-Luc |
|
2012 |
21-22 |
4 |
p. e245-e251 nvt p. |
artikel |