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                             99 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex Wu, Tian-Ying
99 C p.
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2 Alkaloids from Corydalis decumbens modulate neuronal excitability Zhang, Chun-Lei
99 C p.
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3 Alopecines A–E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides Wang, Xiao-Feng
99 C p.
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4 An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity Rao, R. Nishanth
99 C p.
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5 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study AboulWafa, Omaima M.
99 C p.
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6 Anti-cancer potential of sophoridine and its derivatives: Recent progress and future perspectives ur Rashid, Haroon
99 C p.
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7 Anti-inflammatory 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones from agarwood of Aquilaria sinensis Yu, Zhangxin
99 C p.
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8 Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies Ammar, Yousry A.
99 C p.
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9 Anti-tubercular activity of novel class of spiropyrrolidine tethered indenoquinoxaline heterocyclic hybrids Arumugam, Natarajan
99 C p.
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10 A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy Ayati, Adileh
99 C p.
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11 A stilbene dimer and flavonoids from the aerial parts of Chromolaena odorata with proprotein convertase subtilisin/kexin type 9 expression inhibitory activity Pel, Pisey
99 C p.
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12 A trisaccharide phenylethanoid glycoside from Scrophularia flava Grau with potential anti-type 2 diabetic properties by inhibiting α-glucosidase enzyme and decreasing oxidative stress Hamedi, Azadeh
99 C p.
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13 Benzimidazoquinazolines as new potent anti-TB chemotypes: Design, synthesis, and biological evaluation Jadhavar, Pradeep S.
99 C p.
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14 Biocatalytic allylic hydroxylation of unsaturated triterpenes and steroids by Bacillus megaterium CGMCC 1.1741 Wang, Wei
99 C p.
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15 Biogenic synthesis of silica nanoparticles from corn cobs husks. Dependence of the productivity on the method of raw material processing Pieła, Aleksandra
99 C p.
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16 Bromocoumarinplatin, targeting simultaneously mitochondria and nuclei with p53 apoptosis pathway to overcome cisplatin resistance Ma, Jing
99 C p.
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17 Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers Floresta, Giuseppe
99 C p.
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18 Compounds from the fruits of mangrove Sonneratia apetala: Isolation, molecular docking and antiaging effects using a Caenorhabditis elegans model Yi, Xiangxi
99 C p.
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19 Corrigendum to “Engineered β-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregates” [Bioorg. Chem. 96 (2020) 103594] Di Natale, Concetta
99 C p.
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20 Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα Loboda, Kaja Bergant
99 C p.
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21 Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity Ibrahim, Tarek S.
99 C p.
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22 Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents Ye, Tianyu
99 C p.
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23 Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer’s disease Liao, Qinghong
99 C p.
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24 Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors Ibrahim, Tarek S.
99 C p.
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25 Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline template Lin, Yu
99 C p.
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26 Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents Sun, Lianqi
99 C p.
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27 Design, synthesis, in vitro and in silico studies of 2, 3-diaryl benzofuran derivatives as antitubercular agents Bhukya, Balakishan
99 C p.
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28 Design, synthesis, radiolabeling and biological evaluation of new urea-based peptides targeting prostate specific membrane antigen Mosayebnia, Mona
99 C p.
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29 Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib Bielec, Bjoern
99 C p.
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30 Development of small-molecule BRD4 degraders based on pyrrolopyridone derivative Zhang, Jian
99 C p.
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31 Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells Diab, Thoria
99 C p.
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32 Discovery and optimization of novel phenyldiazepine and pyridodiazepine based Aurora kinase inhibitors Tamizharasan, Natarajan
99 C p.
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33 Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors Bahekar, Rajesh
99 C p.
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34 Discovery of novel dual PPARα/δ agonists based on benzimidazole scaffold for the treatment of non-alcoholic fatty liver disease Li, Zheng
99 C p.
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35 Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase Liu, Hao
99 C p.
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36 Discovery of novel pyrazoline derivatives containing methyl-1H-indole moiety as potential inhibitors for blocking APC-Asef interactions Qi, Peng-Fei
99 C p.
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37 Drug discovery approaches targeting the incretin pathway Deng, Xinxian
99 C p.
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38 Editorial Board
99 C p.
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39 Efficient synthesis of β-lactam antibiotics with in situ product removal by a newly isolated penicillin G acylase Pan, Xin
99 C p.
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40 ent-Pimarane diterpenoids from Siegesbeckia glabrescens with anti-inflammatory activity Gao, XiaoXu
99 C p.
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41 Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition Javid, Noman
99 C p.
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42 Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40) Kuranov, Sergey O.
99 C p.
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43 Fluorinated CRA13 analogues: Synthesis, in vitro evaluation, radiosynthesis, in silico and in vivo PET study Hassan, Ahmed H.E.
99 C p.
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44 From nucleus to mitochondria to lysosome selectivity switching in a cyanine probe: The phenolic to methoxy substituent conversion affects probe’s selectivity Abeywickrama, Chathura S.
99 C p.
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45 Gold nanoparticles morphology does not affect the multivalent presentation and antibody recognition of Group A Streptococcus synthetic oligorhamnans Pitirollo, Olimpia
99 C p.
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46 Guaiane type of sesquiterpene with NO inhibitory activity from the root of Wikstroemia indica Liu, Zhihui
99 C p.
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47 1,4,5,6,7,8-Hexahydroquinolines and 5,6,7,8-tetrahydronaphthalenes: A new class of antitumor agents targeting the colchicine binding site of tubulin Shaheen, Mennatallah A.
99 C p.
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48 Identification of N-acyl quinolin-2(1H)-ones as new selective agents against clinical isolates of Acanthamoeba keratitis Reyes-Batlle, María
99 C p.
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49 Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG) Chen, Jungang
99 C p.
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50 Identification of rapid access to polycyclic systems via a base-catalyzed cascade cyclization reaction and their biological evaluation Ling, Taotao
99 C p.
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51 In vivo efficacy studies of novel quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors, in lung cancer xenografts (NCI-H1975) mice models Das, Debasis
99 C p.
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52 Issue TOC
99 C p.
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53 New imidazolone derivatives comprising a benzoate or sulfonamide moiety as anti-inflammatory and antibacterial inhibitors: Design, synthesis, selective COX-2, DHFR and molecular-modeling study Metwally, Nadia Hanafy
99 C p.
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54 Newly reported alkaloids produced by marine-derived Penicillium species (covering 2014–2018) Zhang, Peng
99 C p.
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55 New secondary metabolites with immunosuppressive activity from the phytopathogenic fungus Bipolaris maydis Duan, Xueyan
99 C p.
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56 New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation Liang, Liyun
99 C p.
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57 New 1Z,5Z-diene macrodiolides: Catalytic synthesis, anticancer activity, induction of mitochondrial apoptosis, and effect on the cell cycle Dzhemileva, Lilya U.
99 C p.
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58 Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA binding affinities Kahriman, Nuran
99 C p.
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59 Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies Kadagathur, Manasa
99 C p.
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60 Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies Karimov, Alverdi
99 C p.
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61 N-Trifluoroacetylated pyrazolines: Synthesis, characterization and antimicrobial studies Asad, Mohammad
99 C p.
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62 On-cell saturation transfer difference NMR study of Bombesin binding to GRP receptor Palmioli, Alessandro
99 C p.
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63 One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM Fu, Yajie
99 C p.
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64 Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents Jin, Guofan
99 C p.
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65 PCR incorporation of dUMPs modified with aromatic hydrocarbon substituents of different hydrophilicities: Synthesis of C5-modified dUTPs and PCR studies using Taq, Tth, Vent (exo-) and Deep Vent (exo-) polymerases Zasedateleva, Olga A.
99 C p.
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66 Physicochemical and in vitro cytotoxicity studies of inclusion complex between gemcitabine and cucurbit[7]uril host Buczkowski, Adam
99 C p.
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67 Polyphyllosides A–F, six new spirostanol saponins from the stems and leaves of Paris polyphylla var. chinensis Qin, Xu-Jie
99 C p.
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68 Potent arylamide derivatives as dual-target antifungal agents: Design, synthesis, biological evaluation, and molecular docking studies Dong, Yue
99 C p.
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69 Privileged scaffold inspired design of novel oxime-biphenyl-DAPYs in treatment of HIV-1 Yang, Yang
99 C p.
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70 Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo Huang, Wan-Yun
99 C p.
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71 Quinazoline-4(3H)-one derivatives as novel and potent inhibitors of soluble epoxide hydrolase: Design, synthesis and biological evaluation Hejazi, Leila
99 C p.
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72 Redox cycling of copper by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated modulation of redox scavengers, DNA damage and cell death in diethylnitrosamine induced hepatocellular carcinoma Khan, Saman
99 C p.
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73 Separation and identification of enzyme inhibition peptides from dark tea protein Zhao, Bingli
99 C p.
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74 Seven pairs of new enantiomeric sesquiterpenoids from Curcuma phaeocaulis Liu, Fei
99 C p.
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75 Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking George, Riham F.
99 C p.
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76 Structurally diverse diterpenoids from Pieris japonica as potent analgesics Zheng, Guijuan
99 C p.
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77 Structurally diverse vibralactones produced by the fungus Stereum hirsutum Liang, Yu
99 C p.
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78 Structural modifications of amino acid sequences of radiolabeled peptides for targeted tumor imaging Maleki, Fariba
99 C p.
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79 Symmetric and dissymmetric carbohydrate-phenyl ditriazole derivatives as DNA G-quadruplex ligands: Synthesis, biophysical studies and antiproliferative activity Arévalo-Ruiz, Matilde
99 C p.
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80 Synthesis and anti-hepaticfibrosis of glycyrrhetinic acid derivatives with inhibiting COX-2 Zhang, Qiuping
99 C p.
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81 Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids Singh, Priti
99 C p.
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82 Synthesis and cytotoxic activities of organometallic Ru(II) diamine complexes Kavukcu, Serdar Batıkan
99 C p.
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83 Synthesis, anti-convulsant activity and molecular docking study of novel thiazole pyridazinone hybrid analogues Siddiqui, Aness Ahmad
99 C p.
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84 Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase Ullah, Saif
99 C p.
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85 Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer’s disease Jokar, Safura
99 C p.
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86 Synthesis, characterization, antimicrobial and DNA binding properties of an organic charge transfer complex obtained from pyrazole and chloranilic acid Khan, Ishaat M.
99 C p.
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87 Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins Juang, Yu-Pu
99 C p.
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88 Synthesis of fluorescent G-quadruplex DNA binding ligands for the comparison of terminal group effects in molecular interaction: Phenol versus methoxybenzene Jin, Jingwei
99 C p.
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89 Synthesis of 2-methoxy-3-(thiophen-2-ylmethyl)quinoline containing amino carbinols as antitubercular agents Karkara, Bidhu Bhusan
99 C p.
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90 Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation Roma-Rodrigues, Catarina
99 C p.
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91 Synthesis of novel 1,2-diarylpyrazolidin-3-one–based compounds and their evaluation as broad spectrum antibacterial agents Mokbel, Salma A.
99 C p.
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92 Synthesis of N-substituted indole derivatives as potential antimicrobial and antileishmanial agents Tiwari, Shweta
99 C p.
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93 Synthesis of symmetrical bis-Schiff base-disulfide hybrids as highly effective anti-leishmanial agents Taha, Muhammad
99 C p.
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94 Synthesis of two novel pyrazolo[1,5-a]pyrimidine compounds with antibacterial activity and biophysical insights into their interactions with plasma protein He, Ling-Ling
99 C p.
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95 The anti-inflammatory components from the effective fraction of Syringae Folium (ESF) and its mechanism investigation based on network pharmacology Wang, Yuwei
99 C p.
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96 The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase Omar, Abdelsattar M.
99 C p.
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97 The rise of gingerol as anti-QS molecule: Darkest episode in the LuxR-mediated bioluminescence saga Parmar, Paritosh
99 C p.
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98 1,2,4-Triazolin-5-thione derivatives with anticancer activity as CK1γ kinase inhibitors Pitucha, Monika
99 C p.
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99 Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker Maklad, Raed M.
99 C p.
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                             99 gevonden resultaten
 
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