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                             132 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Amphiphilic azobenzenes: Antibacterial activities and biophysical investigation of their interaction with bacterial membrane lipids Franche, A.
94 C p.
 artikel
2 A novel cathepsin L inhibitor prevents the progression of idiopathic pulmonary fibrosis Yuan, Lei
94 C p.
 artikel
3 Anticancer, antimicrobial activities of quinoline based hydrazone analogues: Synthesis, characterization and molecular docking Katariya, Kanubhai D
94 C p.
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4 Anticancer effects of sodium and potassium quercetin-5′-sulfonates through inhibition of proliferation, induction of apoptosis, and cell cycle arrest in the HT-29 human adenocarcinoma cell line Czerwonka, Arkadiusz
94 C p.
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5 Apoptosis: A target for anticancer therapy with novel cyanopyridines Ismail, Magda M.F.
94 C p.
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6 A review on anti-inflammatory activity of green synthesized zinc oxide nanoparticle: Mechanism-based approach Agarwal, Happy
94 C p.
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7 Aromatic rosane diterpenoids from the roots of Euphorbia ebracteolata and their inhibitory effects against lipase Li, Lu
94 C p.
 artikel
8 Atenolol thiourea hybrid as potent urease inhibitors: Design, biology-oriented drug synthesis, inhibitory activity screening, and molecular docking studies Wahid, Sana
94 C p.
 artikel
9 Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase Wilkinson, Isabel V.L.
94 C p.
 artikel
10 Cloning and characterization of the β-xylosidase from Dictyoglomus turgidum for high efficient biotransformation of 10-deacetyl-7-xylosltaxol Li, Qi
94 C p.
 artikel
11 Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2′-deoxyuridine boron cluster conjugates Saftić, Dijana
94 C p.
 artikel
12 Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer’s disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation Makhaeva, Galina F.
94 C p.
 artikel
13 Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids Abdu-Allah, Hajjaj H.M.
94 C p.
 artikel
14 Corrigendum to “Synthesis and biological evaluation of tetrazole derivatives as TNF-α, IL-6 and COX-2 inhibitors with antimicrobial activity: Computational analysis, molecular modeling study and region-specific cyclization using 2D NMR tools” [Bioorg. Chem. 92 (2019) 103301] Lamie, Phoebe F.
94 C p.
 artikel
15 Coumarin Tröger’s base derivatives with cyanine substitution as selective and sensitive fluorescent lysosomal probes Talianová, Veronika
94 C p.
 artikel
16 Design and synthesis of diphenylpyrimidine derivatives (DPPYs) as potential dual EGFR T790M and FAK inhibitors against a diverse range of cancer cell lines Ai, Min
94 C p.
 artikel
17 Design and synthesis of novel parabanic acid derivatives as anticonvulsants Aboutabl, Mona Elsayed
94 C p.
 artikel
18 Design and synthesis of novel 1-substituted 3-(6-phenoxypyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine analogs as selective BTK inhibitors for the treatment of mantle cell lymphoma Ran, Fansheng
94 C p.
 artikel
19 Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors Bertran, Alexandra
94 C p.
 artikel
20 Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators Fang, Yuanying
94 C p.
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21 Design, molecular modeling and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as inhibitors of topoisomerase II El-Metwally, Souad A.
94 C p.
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22 Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors Vettorazzi, Marcela
94 C p.
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23 Design, preparation and biological evaluation of a 177Lu-labeled somatostatin receptor antagonist for targeted therapy of neuroendocrine tumors Behnammanesh, Hossein
94 C p.
 artikel
24 Design, synthesis and anti-HBV activity of NVR3-778 derivatives Lv, Kai
94 C p.
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25 Design, synthesis and biological evaluation of 2-arylaminopyrimidine derivatives bearing 1,3,8-triazaspiro[4,5]decan-4-one or piperidine-3-carboxamide moiety as novel Type-I1/2 ALK inhibitors Miao, Xiuqi
94 C p.
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26 Design, synthesis and biological evaluation of bicyclic carboxylic acid derivatives as IDO1 inhibitors Cai, Shi
94 C p.
 artikel
27 Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs Li, Shuai
94 C p.
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28 Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease Lan, Jin-Shuai
94 C p.
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29 Design, synthesis and in vitro evaluation of fangchinoline derivatives as potential anticancer agents Zhang, Yan-chun
94 C p.
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30 Design, synthesis, biological evaluation and molecular modeling of novel 1H-pyrrolo[2,3-b]pyridine derivatives as potential anti-tumor agents Wang, Ruifeng
94 C p.
 artikel
31 Design, synthesis, biological evaluation and molecular modeling study of new thieno[2,3-d]pyrimidines with anti-proliferative activity on pancreatic cancer cell lines Salem, Mohamed S.H.
94 C p.
 artikel
32 Design, synthesis, cytotoxicity screening and molecular docking of new 3-cyanopyridines as survivin inhibitors and apoptosis inducers Sabour, Rehab
94 C p.
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33 Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers Mahdy, Hazem A.
94 C p.
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34 Detection techniques of carboxylesterase activity: An update review Lan, Lulu
94 C p.
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35 Development of carbapenem-based fluorogenic probes for the clinical screening of carbapenemase-producing bacteria Kim, Juhyeon
94 C p.
 artikel
36 Development of 1,3-thiazole analogues of imidazopyridines as potent positive allosteric modulators of GABAA receptors Tikhonova, Tatyana A.
94 C p.
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37 Di- and tri-substituted s-triazine derivatives: Synthesis, characterization, anticancer activity in human breast-cancer cell lines, and developmental toxicity in zebrafish embryos El-Faham, Ayman
94 C p.
 artikel
38 Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activities Hu, Qingqing
94 C p.
 artikel
39 Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma Mohamady, Samy
94 C p.
 artikel
40 Discovery of benzo[d]oxazole derivatives as the potent type-I FLT3-ITD inhibitors Bao, Jiyin
94 C p.
 artikel
41 Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor Yeong, Keng Yoon
94 C p.
 artikel
42 Discovery of nitrogenous sesquiterpene quinone derivatives from sponge Dysidea septosa with anti-inflammatory activity in vivo zebrafish model Gui, Yu-Han
94 C p.
 artikel
43 Diterpenoids from the aerial parts of Flueggea acicularis and their activity against RANKL-induced osteoclastogenesis Huang, Dane
94 C p.
 artikel
44 Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties Jiang, Wujiu
94 C p.
 artikel
45 Editorial Board
94 C p.
 artikel
46 Enzymatic synthesis of fatty acid esters of trehalose: Process optimization, characterization of the esters and evaluation of their bioactivities Marathe, Sandesh J.
94 C p.
 artikel
47 E-pharmacophore guided discovery of pyrazolo[1,5-c]quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase Joshi, Gaurav
94 C p.
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48 Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities Attalah, Khalid M.
94 C p.
 artikel
49 Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus Hu, Chun-Fang
94 C p.
 artikel
50 Evaluation of biological activities, and exploration on mechanism of action of matrine–cholesterol derivatives Xu, Jianwei
94 C p.
 artikel
51 Fabrication of nanoparticles from a synthesized peptide amphiphile as a versatile therapeutic cargo for high antiproliferative activity in tumor cells Das, Soumi
94 C p.
 artikel
52 Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5′-3′ connecting linker on the aptamer stability and anticoagulant activity Riccardi, Claudia
94 C p.
 artikel
53 Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity Nunhart, Patrik
94 C p.
 artikel
54 Fluoroaryl analogs of sulforaphane – A group of compounds of anticancer and antimicrobial activity Cierpiał, Tomasz
94 C p.
 artikel
55 Flurbiprofen-chalcone hybrid Mannich base derivatives as balanced multifunctional agents against Alzheimer’s disease: Design, synthesis and biological evaluation Tian, Chaoquan
94 C p.
 artikel
56 Functionalization of 8-17 DNAzymes modulates catalytic efficiency and divalent metal ion preference Du, Shanshan
94 C p.
 artikel
57 Functionalization of 9-thioxanthone at the 1-position: From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest Mokhtari Brikci-Nigassa, Nahida
94 C p.
 artikel
58 Green and facile synthesis of Ag nanoparticles using Crataegus pentagyna fruit extract (CP-AgNPs) for organic pollution dyes degradation and antibacterial application Ebrahimzadeh, Mohammad Ali
94 C p.
 artikel
59 Halogenated aromatic thiosemicarbazones as potent inhibitors of tyrosinase and melanogenesis Hałdys, Katarzyna
94 C p.
 artikel
60 Highly oxygenated polyketides produced by Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the fresh roots of the medicinal plant Artemisia argyi Shi, Xiao-Shan
94 C p.
 artikel
61 ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn. Türkan, Fikret
94 C p.
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62 Identification and characterization of human interferon alpha inhibitors through a WISH cell line-based reporter gene assay Bürgi, Milagros
94 C p.
 artikel
63 Identification of inhibitors of the immunosuppressive enzyme IL4I1 Presset, Marc
94 C p.
 artikel
64 Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: Synthesis, biological activity, crystal structure analysis, and molecular docking studies Mohd Faudzi, Siti Munirah
94 C p.
 artikel
65 Insight into the binding affinity of thiourea in the calcium binding pocket of proteinase K, through high resolution X-ray crystallography Ahmad, Malik Shoaib
94 C p.
 artikel
66 Introducing of acyclonucleoside analogues tethered 1,2,4-triazole as anticancer agents with dual epidermal growth factor receptor kinase and microtubule inhibitors Aouad, Mohamed Reda
94 C p.
 artikel
67 In-vitro Anti-cancer assay and apoptotic cell pathway of newly synthesized benzoxazole-N-heterocyclic hybrids as potent tyrosine kinase inhibitors Desai, Sulaksha
94 C p.
 artikel
68 In vivo evaluation and atom-based 3D-QSAR studies on saponins from shells of Xanthoceras sorbifolium Bunge as anti-AD agents Chen, Gang
94 C p.
 artikel
69 Isobenzofuranone monomer and dimer derivatives from the mangrove endophytic fungus Epicoccum nigrum SCNU-F0002 possess α-glucosidase inhibitory and antioxidant activity Yan, Zhangyuan
94 C p.
 artikel
70 Issue TOC
94 C p.
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71 Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system Gado, Francesca
94 C p.
 artikel
72 Molecular docking, antiproliferative and anticonvulsant activities of swertiamarin isolated from Enicostemma axillare Vaijanathappa, Jaishree
94 C p.
 artikel
73 Neurological and psychiatric management using COMT inhibitors: A review Akhtar, Md Jawaid
94 C p.
 artikel
74 New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay Aly, Ashraf A.
94 C p.
 artikel
75 New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia Bertrand, Jeanluc
94 C p.
 artikel
76 Novel halogenated sulfonamide biguanides with anti-coagulation properties Markowicz-Piasecka, Magdalena
94 C p.
 artikel
77 Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties Bal, Selma
94 C p.
 artikel
78 O-GlcNAcylation of truncated NAC segment alters peptide-dependent effects on α-synuclein aggregation Ryan, Philip
94 C p.
 artikel
79 Optimization of the benzamide fragment targeting the S2′ site leads to potent dipeptidyl peptidase-IV inhibitors Deng, Xiaoyan
94 C p.
 artikel
80 Organic small molecular receptors as fluorimetric/bioimaging probe for extracellular/intracellular zinc sensation Hanif, Muhammad
94 C p.
 artikel
81 Polycyclic furanobutenolide-derived norditerpenoids from the South China Sea soft corals Sinularia scabra and Sinularia polydactyla with immunosuppressive activity Cui, Wan-Xiang
94 C p.
 artikel
82 Polyprenylated xanthones from the twigs and leaves of Garcinia nujiangensis and their cytotoxic evaluation Liu, Xiao-Jia
94 C p.
 artikel
83 Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates Kaproń, Barbara
94 C p.
 artikel
84 Preparation and anti-Raji lymphoma efficacy of a novel pH sensitive and magnetic targeting nanoparticles drug delivery system Cai, Xiaohui
94 C p.
 artikel
85 Prospective computational design and in vitro bio-analytical tests of new chemical entities as potential selective CYP17A1 lyase inhibitors Gumede, N.J.
94 C p.
 artikel
86 Protective effects of polydatin on multiple organ ischemia-reperfusion injury Sun, Zhicheng
94 C p.
 artikel
87 Purification and characterization of β-galactosidase from newly isolated Aspergillus terreus (KUBCF1306) and evaluating its efficacy on breast cancer cell line (MCF-7) Vidya, B.
94 C p.
 artikel
88 ω-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase Dato, Florian M.
94 C p.
 artikel
89 Rational approaches of drug design for the development of selective estrogen receptor modulators (SERMs), implicated in breast cancer Makar, Subhajit
94 C p.
 artikel
90 Semisynthesis and biological evaluation of some novel Mannich base derivatives derived from a natural lignan obovatol as potential antifungal agents Yang, Chun
94 C p.
 artikel
91 Steering the antitumor drug discovery campaign towards structurally diverse indolines Thakur, Amandeep
94 C p.
 artikel
92 Structural and clinical impact of anti-allergy agents: An overview Kapoor, Yagyesh
94 C p.
 artikel
93 Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B Zarei, Omid
94 C p.
 artikel
94 Structure elucidation {spectroscopic, single crystal X-ray diffraction and computational DFT studies} of new tailored benzenesulfonamide derived Schiff base copper(II) intercalating complexes: Comprehensive biological profile {DNA binding, pBR322 DNA cleavage, Topo I inhibition and cytotoxic activity} Afsan, Zeenat
94 C p.
 artikel
95 Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles Smart, Tristan J.
94 C p.
 artikel
96 Synthesis and antibacterial activity of 11,12-cyclic carbonate 4″-O-aralkylacetylhydrazineacyl azithromycin derivatives Yan, Mi
94 C p.
 artikel
97 Synthesis and antibacterial evaluation against resistant Gram-negative bacteria of monobactams bearing various substituents on oxime residue Li, Zhi–Wen
94 C p.
 artikel
98 Synthesis and antibacterial evaluation of a novel library of 2-(thiazol-5-yl)-1,3,4-oxadiazole derivatives against methicillin-resistant Staphylococcus aureus (MRSA) Hannoun, Mohamed H.
94 C p.
 artikel
99 Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures Rebelo, Bárbara A.
94 C p.
 artikel
100 Synthesis and biological evaluation of 1-(benzofuran-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole derivatives as tubulin polymerization inhibitors Qi, Zhi-Yuan
94 C p.
 artikel
101 Synthesis and biological evaluation of new chloro/acetoxy substituted isoindole analogues as new tyrosine kinase inhibitors Köse, Aytekin
94 C p.
 artikel
102 Synthesis and biological evaluation of novel millepachine derivative containing aminophosphonate ester species as novel anti-tubulin agents Huang, Xiaochao
94 C p.
 artikel
103 Synthesis and biological evaluations of novel isoxazoles and furoxan derivative as anti-inflammatory agents Abdelall, Eman K.A.
94 C p.
 artikel
104 Synthesis and cytotoxic activity of chalcone analogues containing a thieno[2,3-d]pyrimidin-2-yl group as the A-ring or B-ring Wang, Fu-Cheng
94 C p.
 artikel
105 Synthesis and discovery of pyrazolo-pyridine analogs as inflammation medications through pro- and anti-inflammatory cytokine and COX-2 inhibition assessments Dennis Bilavendran, J.
94 C p.
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106 Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles Baldisserotto, Anna
94 C p.
 artikel
107 Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A1 and/or A2A receptor antagonists Janse van Rensburg, Helena D.
94 C p.
 artikel
108 Synthesis and evaluation of the antitumor activity of Calix[4]arene l-proline derivatives Oguz, Mehmet
94 C p.
 artikel
109 Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs Attia, Mohamed H.
94 C p.
 artikel
110 Synthesis and molecular docking studies of imines as α-glucosidase and α-amylase inhibitors Aispuro-Pérez, Analy
94 C p.
 artikel
111 Synthesis and molecular docking studies of some novel antimicrobial benzamides Acar, Cemre
94 C p.
 artikel
112 Synthesis, characterization and molecular docking of some novel hydrazonothiazolines as urease inhibitors Shehzad, Muhammad Tariq
94 C p.
 artikel
113 Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study Rahim, Fazal
94 C p.
 artikel
114 Synthesis, in vitro α-amylase inhibitory, and radicals (DPPH & ABTS) scavenging potentials of new N-sulfonohydrazide substituted indazoles Rafique, Rafaila
94 C p.
 artikel
115 Synthesis, in vitro and in vivo biological evaluation of dihydroartemisinin derivatives with potential anti-Toxoplasma gondii agents Deng, Hao
94 C p.
 artikel
116 Synthesis, molecular docking, dynamic simulations, kinetic mechanism, cytotoxicity evaluation of N-(substituted-phenyl)-4-{(4-[(E)-3-phenyl-2-propenyl]-1-piperazinyl} butanamides as tyrosinase and melanin inhibitors: In vitro, in vivo and in silico approaches Raza, Hussain
94 C p.
 artikel
117 Synthesis of chlorophyll-a homologs by C132-substitutions and their physico- and biochemical properties Ogasawara, Shin
94 C p.
 artikel
118 Synthesis of d-ring modified acid hydrazide derivatives of podophyllotoxin and their anticancer studies as Tubulin inhibiting agents Nerella, Srinivas
94 C p.
 artikel
119 Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability Nekvinda, Jan
94 C p.
 artikel
120 Synthesis of new indazole based dual inhibitors of α-glucosidase and α-amylase enzymes, their in vitro, in silico and kinetics studies Rafique, Rafaila
94 C p.
 artikel
121 Synthesis of novel 2-aminobenzothiazole derivatives as potential antimicrobial agents with dual DNA gyrase/topoisomerase IV inhibition Ismail, Magda M.F.
94 C p.
 artikel
122 Synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives: Antimicrobial activity, DNA Gyrase inhibition and molecular docking Abd El-Aleam, Rehab H.
94 C p.
 artikel
123 Taxumarienes A–G, seven new α-glucosidase inhibitory taxane-diterpenoids from the leaves of Taxus mairei Chen, Kang
94 C p.
 artikel
124 The anti-cancer compound Schweinfurthin A targets Osh2 and disrupts lipid metabolism in the yeast model Moosavi, Behrooz
94 C p.
 artikel
125 The first enzyme-promoted addition of nitromethane to imines (aza-Henry reaction) Janicki, Ignacy
94 C p.
 artikel
126 The larvicidal activity of natural inspired piperine-based dienehydrazides against Culex pipiens Tantawy, Ahmed H.
94 C p.
 artikel
127 The noncovalent conjugations of bovine serum albumin with three structurally different phytosterols exerted antiglycation effects: A study with AGEs-inhibition, multispectral, and docking investigations Sobhy, Remah
94 C p.
 artikel
128 Thermostability detection and optimization of glycoengineered antibodies and antibody-drug conjugates based on differential scanning flouremitry analysis Qin, Ken
94 C p.
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129 The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells Saavedra, Ester
94 C p.
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130 Three new bioactive natural products from the fungus Talaromyces assiutensis JTY2 Cai, Jin
94 C p.
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131 Total synthesis and anti-inflammatory evaluation of violacin A and its analogues Liu, Qingyin
94 C p.
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132 Water-soluble betaines and amines based on thiacalix[4]arene scaffold as new cholinesterase inhibitors Padnya, Pavel L.
94 C p.
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                             132 gevonden resultaten
 
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