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                             102 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A dual-emission fluorescent probe for discriminating cysteine from homocysteine and glutathione in living cells and zebrafish models Lu, Zhengliang

92 C p.
artikel
2 A novel adaptive fluorescent probe for cell labelling Coman, Anca G.

92 C p.
artikel
3 Anti-cancer activity of the cell membrane-permeable phytic acid prodrug Masunaga, Takuya

92 C p.
artikel
4 Anti-inflammatory flavonoids from root bark of Broussonetia papyrifera in LPS-stimulated RAW264.7 cells Ryu, Hyung Won

92 C p.
artikel
5 Antiprotozoal activities of marine polyether triterpenoids Díaz-Marrero, Ana R.

92 C p.
artikel
6 Arylpropionic acid-derived NSAIDs: New insights on derivatization, anticancer activity and potential mechanism of action Gouda, Ahmed M.

92 C p.
artikel
7 Biflavones from Ginkgo biloba as inhibitors of human thrombin Chen, Tian-Ran

92 C p.
artikel
8 Bioactivity-based analysis and chemical characterization of hypoglycemic and antioxidant components from Artemisia argyi Xiao, Jian-Qi

92 C p.
artikel
9 Biscoumarin-1,2,3-triazole hybrids as novel anti-diabetic agents: Design, synthesis, in vitro α-glucosidase inhibition, kinetic, and docking studies Asgari, Mohammad Sadegh

92 C p.
artikel
10 Chemical constituents and synergistic anti-gout studies on Eurycoma longifolia and potential mechanisms evaluation based on systemic analysis approach Liu, Ying

92 C p.
artikel
11 Chemical constituents from Alismatis Rhizoma and their anti-inflammatory activities in vitro and in vivo Liu, Shan-shan

92 C p.
artikel
12 Chemical constituents from Lonicera japonica flower buds and their anti-hepatoma and anti-HBV activities Ge, Lanlan

92 C p.
artikel
13 Corrigendum to “Design, synthesis and biological evaluation of pyrazolopyrimidinone based potent and selective PDE5 inhibitors for treatment of erectile dysfunction” [Bioorg. Chem. 89 (2019) 103022] Reddy, G. Lakshma

92 C p.
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14 Coumarin tethered cyclic imides as efficacious glucose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin Reddy, Dinesh S.

92 C p.
artikel
15 Curcumane C and (±)-curcumane D, an unusual seco-cadinane sesquiterpenoid and a pair of unusual nor-bisabolane enantiomers with significant vasorelaxant activity from Curcuma longa Qiao, Ming-Ming

92 C p.
artikel
16 Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B Ottanà, Rosaria

92 C p.
artikel
17 Design and synthesis of fluorogenic substrate-based probes for detecting Cathepsin B activity Wang, Shusheng

92 C p.
artikel
18 Design and synthesis of novel pyridazinoquinazoline derivatives as potent VEGFR-2 inhibitors: In vitro and in vivo study El-Gazzar, Marwa G.

92 C p.
artikel
19 Design, synthesis and antifungal activity evaluation of isocryptolepine derivatives Li, Jun-cai

92 C p.
artikel
20 Design, synthesis, and biological activity of Plastoquinone analogs as a new class of anticancer agents Bayrak, Nilüfer

92 C p.
artikel
21 Design, synthesis, and biological evaluation of novel dual FFA1 (GPR40)/PPARδ agonists as potential anti-diabetic agents Li, Zheng

92 C p.
artikel
22 Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors Maheshwari, Neelesh

92 C p.
artikel
23 Design, synthesis and biological evaluation of theophylline containing variant acetylene derivatives as α-amylase inhibitors Ruddarraju, Radhakrishnam Raju

92 C p.
artikel
24 Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents Zabiulla,

92 C p.
artikel
25 Design, synthesis and molecular docking of novel pyrazolo[1,5-a][1,3,5]triazine derivatives as CDK2 inhibitors Oudah, Khulood H.

92 C p.
artikel
26 Design, synthesis, and molecular docking study of new piperazine derivative as potential antimicrobial agents Patil, Mahadev

92 C p.
artikel
27 Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2 Manjula, Ramu

92 C p.
artikel
28 Design, synthesis, in vitro evaluation, molecular docking and ADME properties studies of hybrid bis-coumarin with thiadiazole as a new inhibitor of Urease Alomari, Munther

92 C p.
artikel
29 Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3Kα Yin, Yong

92 C p.
artikel
30 Dihydro-β-agarofuran sesquiterpenoid derivatives with anti-inflammatory activity from the leaves of Tripterygium wilfordii He, Qing-Jun

92 C p.
artikel
31 Discovery and optimization of 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one derivatives as mTORC1/mTORC2 dual inhibitors Hu, Shengquan

92 C p.
artikel
32 Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening Yang, Hongyu

92 C p.
artikel
33 Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR Fang, Wei-Shuo

92 C p.
artikel
34 Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study Sigalapalli, Dilep Kumar

92 C p.
artikel
35 Discovery of diverse diterpenoid scaffolds from Euphorbia antiquorum and their activity against RANKL-induced osteoclastogenesis Yin, Zhi-Yong

92 C p.
artikel
36 Discovery of 2-ethoxy-4-(methoxymethyl)benzamide derivatives as potent and selective PTP1B inhibitors Xie, Fangzhou

92 C p.
artikel
37 Discovery of HWL-088: A highly potent FFA1/GPR40 agonist bearing a phenoxyacetic acid scaffold Li, Zheng

92 C p.
artikel
38 Discovery of indoline derivatives that inhibit esophageal squamous cell carcinoma growth by Noxa mediated apoptosis Fu, Dong-Jun

92 C p.
artikel
39 Disulfide bridge as a linker in nucleic acids’ bioconjugation. Part I: An overview of synthetic strategies Stasińska, Anna R.

92 C p.
artikel
40 Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance Huang, Xiaochao

92 C p.
artikel
41 Dual VEGFR-2/PIM-1 kinase inhibition towards surmounting the resistance to antiangiogenic agents via hybrid pyridine and thienopyridine-based scaffolds: Design, synthesis and biological evaluation Rizk, Ola H.

92 C p.
artikel
42 Editorial Board
92 C p.
artikel
43 Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo Guo, Eryan

92 C p.
artikel
44 Exploring antidiabetic potential of adamantyl-thiosemicarbazones via aldose reductase (ALR2) inhibition Shehzad, Muhammad Tariq

92 C p.
artikel
45 First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone deacetylase inhibitors and antitumor agents Okasha, Rawda M.

92 C p.
artikel
46 Geranylated carbazole alkaloids with potential neuroprotective activities from the stems and leaves of Clausena lansium Liu, Yan-Ping

92 C p.
artikel
47 Germacrane-type sesquiterpenoids with cytotoxic activity from Sigesbeckia orientalis Liu, Na

92 C p.
artikel
48 Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships Petrova, Yoana D.

92 C p.
artikel
49 Identification of potential inflammatory inhibitors from Aster tataricus Su, Xiang Dong

92 C p.
artikel
50 Immunomodulatory activities of zinc(II)phthalocyanine on the mammalian macrophages through p38 pathway: Potential ex vivo immunomodulatory PDT reagents Yüzer, Abdulcelil

92 C p.
artikel
51 In vitro assessment of 3-alkoxy-5-nitroindazole-derived ethylamines and related compounds as potential antileishmanial drugs Martín-Montes, Álvaro

92 C p.
artikel
52 Issue TOC
92 C p.
artikel
53 Juniperanol: First total synthesis and evaluation in Type 2 Diabetes disease Carrër, A.

92 C p.
artikel
54 Molecular interaction of manganese based carbon monoxide releasing molecule (MnCORM) with human serum albumin (HSA) Vidhyapriya, Pitchavel

92 C p.
artikel
55 New A2A adenosine receptor antagonists: a structure-based upside-down interaction in the receptor cavity Lambertucci, Catia

92 C p.
artikel
56 New carboxamides bearing benzenesulphonamides: Synthesis, molecular docking and pharmacological properties Eze, Florence Uchenna

92 C p.
artikel
57 New cytotoxic tricycloalternarenes from fungus Alternaria brassicicola Li, Fengli

92 C p.
artikel
58 New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition Abdelgawad, Mohamed A.

92 C p.
artikel
59 New series of fused pyrazolopyridines: Synthesis, molecular modeling, antimicrobial, antiquorum-sensing and antitumor activities El-Gohary, N.S.

92 C p.
artikel
60 New triazinoindole bearing thiazole/oxazole analogues: Synthesis, α-amylase inhibitory potential and molecular docking study Rahim, Fazal

92 C p.
artikel
61 NO inhibitory diterpenoids as potential anti-inflammatory agents from Euphorbia antiquorum An, Lijun

92 C p.
artikel
62 Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents Yevglevskis, Maksims

92 C p.
artikel
63 Novel conjugates with dual suppression of glutathione S-transferases and tryptophan-2,3-dioxygenase activities for improving hepatocellular carcinoma therapy Hua, Shixian

92 C p.
artikel
64 Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity Huan, Le Cong

92 C p.
artikel
65 Novel inhibitors of leukocyte transendothelial migration Getter, Tamar

92 C p.
artikel
66 Novel N-benzylpyridinium moiety linked to arylisoxazole derivatives as selective butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study Vafadarnejad, Fahimeh

92 C p.
artikel
67 Novel pyridazinone derivatives as butyrylcholinesterase inhibitors Dundar, Yasemin

92 C p.
artikel
68 Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities Yang, Fang

92 C p.
artikel
69 Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins Qiu, Yangyi

92 C p.
artikel
70 Optimization study towards more potent thiazolidine-2,4-dione IKK-β modulator: Synthesis, biological evaluation and in silico docking simulation Elkamhawy, Ahmed

92 C p.
artikel
71 Physapubescin I from husk tomato suppresses SW1990 cancer cell growth by targeting kidney-type glutaminase Yang, Kai-Yin

92 C p.
artikel
72 Promising antibacterial agents against multidrug resistant Staphylococcus aureus Gatadi, Srikanth

92 C p.
artikel
73 Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials Taslimi, Parham

92 C p.
artikel
74 Rational design of some substituted phenyl azanediyl (bis) methylene phosphonic acid derivatives as potential anticancer agents and imaging probes: Computational inputs, chemical synthesis, radiolabeling, biodistribution and gamma scintigraphy Khedr, Mohammed A.

92 C p.
artikel
75 Recent advances in the synthetic and medicinal perspective of quinolones: A review Dhiman, Prashant

92 C p.
artikel
76 Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity Kalisha Vali, Y.

92 C p.
artikel
77 2-Styrylchromone derivatives as potent and selective monoamine oxidase B inhibitors Takao, Koichi

92 C p.
artikel
78 Synthesis and biological evaluation of a novel series of curcumin-peptide derivatives as PepT1-mediated transport drugs Zhang, Jiyun

92 C p.
artikel
79 Synthesis and biological evaluation of tetrazole derivatives as TNF-α, IL-6 and COX-2 inhibitors with antimicrobial activity: Computational analysis, molecular modeling study and region-specific cyclization using 2D NMR tools Lamie, Phoebe F.

92 C p.
artikel
80 Synthesis and biological evaluation of thiazolidine-2,4-dione-pyrazole conjugates as antidiabetic, anti-inflammatory and antioxidant agents Bansal, Garima

92 C p.
artikel
81 Synthesis and comparative carbonic anhydrase inhibition of new Schiff’s bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds El-Azab, Adel S.

92 C p.
artikel
82 Synthesis and investigation of inhibitory activities of imidazole derivatives against the metallo-β-lactamase IMP-1 Khalili Arjomandi, Omid

92 C p.
artikel
83 Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors Guazzelli, Lorenzo

92 C p.
artikel
84 Synthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents Zhang, Ya-Liang

92 C p.
artikel
85 Synthesis, biological activity and molecular modeling of a new series of condensed 1,2,4-triazoles El Bakri, Youness

92 C p.
artikel
86 Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors Yamali, Cem

92 C p.
artikel
87 Synthesis, biological evaluation and molecular docking analysis of novel benzopyrimidinone derivatives as potential anti-tyrosinase agents Chortani, Sarra

92 C p.
artikel
88 Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs Ahmad, Gulraiz

92 C p.
artikel
89 Synthesis of d-desthiobiotin-AI-2 as a novel chemical probe for autoinducer-2 quorum sensing receptors Miranda, Vanessa

92 C p.
artikel
90 Synthesis of Mitomycin C and decarbamoylmitomycin C N 6 deoxyadenosine-adducts Zheng, Maggie

92 C p.
artikel
91 Synthesis, structural characterization and in vivo anti-diabetic evaluation of some new sulfonylurea derivatives in normal and silicate coated nanoparticle forms as anti-hyperglycemic agents Sroor, Farid M.

92 C p.
artikel
92 Targeted 8-hydroxyquinoline fragment based small molecule drug discovery against neglected botulinum neurotoxin type F Chauhan, Ritika

92 C p.
artikel
93 The application of safe for humans and the environment Polyversum antifungal agent containing living cells of Pythium oligandrum for biotransformation of prochiral ketones Kołodziejska, Renata

92 C p.
artikel
94 The modulating effect of lipid bilayer/p-coumaric acid interactions on electrical properties of model lipid membranes and human glioblastoma cells Naumowicz, Monika

92 C p.
artikel
95 The role of long noncoding RNA in major human disease Zhang, Xiaoli

92 C p.
artikel
96 Triazolopyridazine derivatives: Synthesis, cytotoxic evaluation, c-Met kinase activity and molecular docking Ahmed, Eman M.

92 C p.
artikel
97 Tyrosinase inhibitory effects of Vinca major and its secondary metabolites: Enzyme kinetics and in silico inhibition model of the metabolites validated by pharmacophore modelling Sari, Suat

92 C p.
artikel
98 Ultrasound mediated efficient synthesis of new 4-oxoquinazolin-3(4H)-yl)furan-2-carboxamides as potent tyrosinase inhibitors: Mechanistic approach through chemoinformatics and molecular docking studies Dige, Nilam C.

92 C p.
artikel
99 Umbelliferone derivatives exert neuroprotective effects by inhibiting monoamine oxidase A, self-amyloidβ aggregation, and lipid peroxidation Seong, Su Hui

92 C p.
artikel
100 Variedly connected 1,8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation Shalini,

92 C p.
artikel
101 Vernodalidimer L, a sesquiterpene lactone dimer from Vernonia extensa and anti-tumor effects of vernodalin, vernolepin, and vernolide on HepG2 liver cancer cells Thongnest, Sanit

92 C p.
artikel
102 Xanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation Jo, Yang Hee

92 C p.
artikel
                             102 gevonden resultaten
 
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