| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
An eco-friendly catalytic system for multicomponent, one-pot synthesis of novel spiro-chromeno indoline-triones and their anti-prostate cancer potentials evaluated via alkaline phosphatase inhibition mechanism
|
Kumar, M. Rajesh
|
|
2018
|
81 |
C |
p. 44-54
|
artikel
|
| 2 |
Aryl fluorosulfate analogues as potent antimicrobial agents: SAR, cytotoxicity and docking studies
|
Ravindar, Lekkala
|
|
2018
|
81 |
C |
p. 107-118
|
artikel
|
| 3 |
A simple boronic acid-based fluorescent probe for selective detection of hydrogen peroxide in solutions and living cells
|
Han, Jialing
|
|
2018
|
81 |
C |
p. 362-366
|
artikel
|
| 4 |
Benzylidine indane-1,3-diones: As novel urease inhibitors; synthesis, in vitro, and in silico studies
|
Bano, Bilquees
|
|
2018
|
81 |
C |
p. 658-671
|
artikel
|
| 5 |
Bioactive compounds from sclerotia extract of Poria cocos that control adipocyte and osteoblast differentiation
|
Lee, Seulah
|
|
2018
|
81 |
C |
p. 27-34
|
artikel
|
| 6 |
Bioactive seco-abietane rearranged diterpenoids from the aerial parts of Salvia prionitis
|
Li, Lingnan
|
|
2018
|
81 |
C |
p. 454-460
|
artikel
|
| 7 |
Characterization of a α-l-rhamnosidase from Bacteroides thetaiotaomicron with high catalytic efficiency of epimedin C
|
Wu, Tao
|
|
2018
|
81 |
C |
p. 461-467
|
artikel
|
| 8 |
Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin–proteasome pathway
|
Chen, Hong
|
|
2018
|
81 |
C |
p. 536-544
|
artikel
|
| 9 |
Conjugation of antifungal benzoic acid derivatives as a path for detoxification in Penicillium brasilianum, an endophyte from Melia azedarach
|
Fill, Taícia Pacheco
|
|
2018
|
81 |
C |
p. 367-372
|
artikel
|
| 10 |
Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation
|
He, Qi
|
|
2018
|
81 |
C |
p. 512-528
|
artikel
|
| 11 |
Cytotoxic ent-Abietane-type diterpenoids from the roots of Euphorbia ebracteolata
|
Han, Chunhui
|
|
2018
|
81 |
C |
p. 93-97
|
artikel
|
| 12 |
Cytotoxic withanolides from the aerial parts of Tubocapsicum anomalum
|
Wang, Si-Bei
|
|
2018
|
81 |
C |
p. 396-404
|
artikel
|
| 13 |
Design and synthesis of structurally defined heparan sulfate (HS)-FK506 conjugates as an exogenous approach to investigate biological functions of nucleus HS
|
Li, MaoLin
|
|
2018
|
81 |
C |
p. 203-210
|
artikel
|
| 14 |
Design, synthesis and biological evaluation N 2-(2-alkyoxy-6-aliphatic aminopyridin-3-yl)-2,4-diaminepyrimidine derivatives bearing acylamino or DBTD ‘head’ as potential ALK inhibitors
|
Xing, Lingyun
|
|
2018
|
81 |
C |
p. 689-699
|
artikel
|
| 15 |
Design, synthesis and evaluation of new classes of nonquaternary reactivators for acetylcholinesterase inhibited by organophosphates
|
Wei, Zhao
|
|
2018
|
81 |
C |
p. 681-688
|
artikel
|
| 16 |
Design, synthesis, crystal structures and anticancer activity of 4-substituted quinolines to target PDK1
|
Vennila, K.N.
|
|
2018
|
81 |
C |
p. 184-190
|
artikel
|
| 17 |
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis
|
Floresta, Giuseppe
|
|
2018
|
81 |
C |
p. 334-339
|
artikel
|
| 18 |
4,5-Diazafluorene N-glycopyranosyl hydrazones as scaffolds for potential bioactive metallo-organic compounds: Synthesis, structural study and cytotoxic activity
|
Jäger, Sebastian
|
|
2018
|
81 |
C |
p. 405-413
|
artikel
|
| 19 |
Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies
|
Das, Mamali
|
|
2018
|
81 |
C |
p. 340-349
|
artikel
|
| 20 |
Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells
|
Yuan, Lei
|
|
2018
|
81 |
C |
p. 672-680
|
artikel
|
| 21 |
Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity
|
Bian, Jinlei
|
|
2018
|
81 |
C |
p. 373-381
|
artikel
|
| 22 |
DNA-binding, enzyme inhibition, and photochemical properties of chalcone-containing metallophthalocyanine compounds
|
Özen, Furkan
|
|
2018
|
81 |
C |
p. 71-78
|
artikel
|
| 23 |
Editorial Board
|
|
|
2018
|
81 |
C |
p. i
|
artikel
|
| 24 |
Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro, and in silico evaluation
|
Khan, Momin
|
|
2018
|
81 |
C |
p. 157-167
|
artikel
|
| 25 |
Ginkgolic acid as a dual-targeting inhibitor for protein tyrosine phosphatases relevant to insulin resistance
|
Yoon, Sun-Young
|
|
2018
|
81 |
C |
p. 264-269
|
artikel
|
| 26 |
α-Glucosidase inhibitory effects of polyphenols from Geranium asphodeloides: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
|
Renda, Gülin
|
|
2018
|
81 |
C |
p. 545-552
|
artikel
|
| 27 |
Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics
|
Drewniak, Magda
|
|
2018
|
81 |
C |
p. 356-361
|
artikel
|
| 28 |
Highly functionalized 2-amino-4H-pyrans as potent cholinesterase inhibitors
|
Kumar, Raju Suresh
|
|
2018
|
81 |
C |
p. 134-143
|
artikel
|
| 29 |
Identification and characterization of a highly S-enantioselective halohydrin dehalogenase from Tsukamurella sp. 1534 for kinetic resolution of halohydrins
|
Wan, Nanwei
|
|
2018
|
81 |
C |
p. 529-535
|
artikel
|
| 30 |
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
|
Zhu, Kongkai
|
|
2018
|
81 |
C |
p. 289-298
|
artikel
|
| 31 |
Identification of human, rat and mouse hydrolyzing enzymes bioconverting amino acid ester prodrug of ketoprofen
|
Huttunen, K.M.
|
|
2018
|
81 |
C |
p. 494-503
|
artikel
|
| 32 |
Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling
|
Adel, Mai
|
|
2018
|
81 |
C |
p. 612-629
|
artikel
|
| 33 |
Identification of novel and selective non-peptide inhibitors targeting the polo-box domain of polo-like kinase 1
|
Chen, Yanhong
|
|
2018
|
81 |
C |
p. 278-288
|
artikel
|
| 34 |
Inhibitory properties of aromatic thiosemicarbazones on mushroom tyrosinase: Synthesis, kinetic studies, molecular docking and effectiveness in melanogenesis inhibition
|
Hałdys, K.
|
|
2018
|
81 |
C |
p. 577-586
|
artikel
|
| 35 |
Issue TOC
|
|
|
2018
|
81 |
C |
p. ii-xxii
|
artikel
|
| 36 |
Modulation of the mobility of a key region in human galactokinase: Impacts on catalysis and stability
|
McAuley, Margaret
|
|
2018
|
81 |
C |
p. 649-657
|
artikel
|
| 37 |
Multi-targeted dihydrazones as potent biotherapeutics
|
Li, Chen
|
|
2018
|
81 |
C |
p. 389-395
|
artikel
|
| 38 |
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones
|
Tugrak, Mehtap
|
|
2018
|
81 |
C |
p. 433-439
|
artikel
|
| 39 |
New bio-sensitive and biologically active single crystal of pyrimidine scaffold ligand and its gold and platinum complexes: DFT, antimicrobial, antioxidant, DNA interaction, molecular docking with DNA/BSA and anticancer studies
|
Sankarganesh, Murugesan
|
|
2018
|
81 |
C |
p. 144-156
|
artikel
|
| 40 |
New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents
|
Nazir, Majid
|
|
2018
|
81 |
C |
p. 253-263
|
artikel
|
| 41 |
Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumor-associated isozyme IX
|
Mikuš, Peter
|
|
2018
|
81 |
C |
p. 241-252
|
artikel
|
| 42 |
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials
|
Zengin, Mustafa
|
|
2018
|
81 |
C |
p. 119-126
|
artikel
|
| 43 |
Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
|
Nguyen, Phuong Chi
|
|
2018
|
81 |
C |
p. 414-424
|
artikel
|
| 44 |
Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis
|
Joshi, Shrinivas D.
|
|
2018
|
81 |
C |
p. 440-453
|
artikel
|
| 45 |
Piperazine: An excellent catalyst for the synthesis of 2-amino-3-cyano-4H-pyrans derivatives in aqueous medium
|
Yousefi, Maryam Rastgoo
|
|
2018
|
81 |
C |
p. 326-333
|
artikel
|
| 46 |
Polyamine derivatives from the bee pollen of Quercus mongolica with tyrosinase inhibitory activity
|
Kim, Seon Beom
|
|
2018
|
81 |
C |
p. 127-133
|
artikel
|
| 47 |
Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies
|
Abd El-Karim, Somaia S.
|
|
2018
|
81 |
C |
p. 481-493
|
artikel
|
| 48 |
Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer
|
Gera, János
|
|
2018
|
81 |
C |
p. 211-221
|
artikel
|
| 49 |
Six kanshone C-derived sesquiterpenoid hybrids nardochalaristolones A–D, nardoflavaristolone A and dinardokanshone F from Nardostachys jatamansi DC.
|
Deng, Xu
|
|
2018
|
81 |
C |
p. 35-43
|
artikel
|
| 50 |
Stereoisomeric guaiacylglycerol-β-coniferyl aldehyde ether induces distinctive apoptosis by downregulation of MEK/ERK pathway in hepatocellular carcinoma cells
|
Yao, Guo-Dong
|
|
2018
|
81 |
C |
p. 382-388
|
artikel
|
| 51 |
Synthesis and biological evaluation of (3′-amino-[1,1′-biphenyl]-4-yl) sulfamic acid derivatives as novel HPTPβ inhibitors
|
Zhang, Wenjuan
|
|
2018
|
81 |
C |
p. 270-277
|
artikel
|
| 52 |
Synthesis and biological evaluation of N-aryl-2-phenyl-hydrazinecarbothioamides: Experimental and theoretical analysis on tyrosinase inhibition and interaction with HSA
|
Sousa-Pereira, Danilo
|
|
2018
|
81 |
C |
p. 79-87
|
artikel
|
| 53 |
Synthesis and biological screening of new thiazolo[4,5-d]pyrimidine and dithiazolo[3,2-a:5′,4′-e]pyrimidinone derivatives as antimicrobial, antiquorum-sensing and antitumor agents
|
Abd Elhameed, Alaa A.
|
|
2018
|
81 |
C |
p. 299-310
|
artikel
|
| 54 |
Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives
|
Fouad, Mahasen M.
|
|
2018
|
81 |
C |
p. 587-598
|
artikel
|
| 55 |
Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors
|
Mohamed, Noha G.
|
|
2018
|
81 |
C |
p. 599-611
|
artikel
|
| 56 |
Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes
|
Majcher, Urszula
|
|
2018
|
81 |
C |
p. 553-566
|
artikel
|
| 57 |
Synthesis, biological activity and structure activity relationship studies of novel conazole analogues via conventional, microwave and ultrasound mediated techniques
|
Mermer, Arif
|
|
2018
|
81 |
C |
p. 55-70
|
artikel
|
| 58 |
Synthesis, biological evaluation and docking study of N-(2-(3,4,5-trimethoxybenzyl)benzoxazole-5-yl) benzamide derivatives as selective COX-2 inhibitor and anti-inflammatory agents
|
Kaur, Avneet
|
|
2018
|
81 |
C |
p. 191-202
|
artikel
|
| 59 |
Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism
|
Angeli, Andrea
|
|
2018
|
81 |
C |
p. 642-648
|
artikel
|
| 60 |
Synthesis of 1H-1,2,3-triazole derivatives as new α-glucosidase inhibitors and their molecular docking studies
|
Avula, Satya Kumar
|
|
2018
|
81 |
C |
p. 98-106
|
artikel
|
| 61 |
Synthesis of matrinic amide derivatives containing 1,3,4-thiadiazole scaffold as insecticidal/acaricidal agents
|
Lv, Min
|
|
2018
|
81 |
C |
p. 88-92
|
artikel
|
| 62 |
Synthesis of new 3-phenylquinazolin-4(3H)-one derivatives as potent antibacterial agents effective against methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA)
|
Gatadi, Srikanth
|
|
2018
|
81 |
C |
p. 175-183
|
artikel
|
| 63 |
Synthesis of novel 1,2-bis-quinolinyl-1,4-naphthoquinones: ERK2 inhibition, cytotoxicity and molecular docking studies
|
Aly, Ashraf A.
|
|
2018
|
81 |
C |
p. 700-712
|
artikel
|
| 64 |
Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties
|
Buğday, Nesrin
|
|
2018
|
81 |
C |
p. 311-318
|
artikel
|
| 65 |
The azatryptophan-based fluorescent platform for in vitro rapid screening of inhibitors disrupting IKKβ-NEMO interaction
|
Chao, Wei-Chih
|
|
2018
|
81 |
C |
p. 504-511
|
artikel
|
| 66 |
Thiazolo[3,2-a]pyrimidin-5-one derivatives as a novel class of 11β-hydroxysteroid dehydrogenase inhibitors
|
Studzińska, Renata
|
|
2018
|
81 |
C |
p. 21-26
|
artikel
|
| 67 |
1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies
|
Tariq, Sana
|
|
2018
|
81 |
C |
p. 630-641
|
artikel
|
| 68 |
1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity
|
Naaz, Fatima
|
|
2018
|
81 |
C |
p. 1-20
|
artikel
|
| 69 |
Trichocarotins A–H and trichocadinin A, nine sesquiterpenes from the marine-alga-epiphytic fungus Trichoderma virens
|
Shi, Zhen-Zhen
|
|
2018
|
81 |
C |
p. 319-325
|
artikel
|
| 70 |
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer
|
Eldehna, Wagdy M.
|
|
2018
|
81 |
C |
p. 425-432
|
artikel
|
| 71 |
Tyrosinase inhibition by some flavonoids: Inhibitory activity, mechanism by in vitro and in silico studies
|
Şöhretoğlu, Didem
|
|
2018
|
81 |
C |
p. 168-174
|
artikel
|
| 72 |
Ugi multicomponent-reaction: Syntheses of cytotoxic dehydroabietylamine derivatives
|
Wiemann, Jana
|
|
2018
|
81 |
C |
p. 567-576
|
artikel
|
| 73 |
Unexpected effect of cyclodepsipeptides bearing a sulfonylhydrazide moiety towards histone deacetylase activity
|
Létévé, Mathieu
|
|
2018
|
81 |
C |
p. 222-233
|
artikel
|
| 74 |
Unusual ent-atisane type diterpenoids with 2-oxopropyl skeleton from the roots of Euphorbia ebracteolata and their antiviral activity against human rhinovirus 3 and enterovirus 71
|
Wang, Bo
|
|
2018
|
81 |
C |
p. 234-240
|
artikel
|
| 75 |
Unveiling novel 2-cyclopropyl-3-ethynyl-4-(4-fluorophenyl)quinolines as GPCR ligands via PI3-kinase/PAR-1 antagonism and platelet aggregation valuations; development of a new class of anticancer drugs with thrombolytic effects
|
Thangarasu, P.
|
|
2018
|
81 |
C |
p. 468-480
|
artikel
|
| 76 |
Xylarianins A-D from the endophytic fungus Xylaria sp. SYPF 8246 as natural inhibitors of human carboxylesterase 2
|
Zhang, Juan
|
|
2018
|
81 |
C |
p. 350-355
|
artikel
|
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