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                             64 results found
no title author magazine year volume issue page(s) type
1 A calmodulin-derived peptide TI-16 inhibits Alzheimer's disease progression by decreasing Aβ burden and restoring calcium dyshomeostasis Su, Jingyang

160 C p.
article
2 A comprehensive review on anti-inflammatory, antibacterial, anticancer and antifungal properties of several bivalent transition metal complexes AlAli, Anas

160 C p.
article
3 A double-ionic macrocycle based on cyanostilbene: First organic fluorescence sensor based small molecular system for detecting cholesterol Wu, Yunmei

160 C p.
article
4 A fluorometric and naked eye readable neuraminidase probe for influenza virus detection Chang, Hao

160 C p.
article
5 A novel photoactivatable coumarin-based fluorescent “turn-on” probe: Synthesis and applications for H2S detection in living cells and zebrafish models Sontisiri, Pakornsiri

160 C p.
article
6 A novel Quinazoline derivative exerts anti-tumor effects in non-small cell lung cancer through Wnt/β-catenin pathway inhibition Zhao, Menglong

160 C p.
article
7 A rationale approach in developing proline based small peptide as U-shaped analogues of arachidonic acid: Dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for developing anti-inflammatory agents Vivesh, Vivesh

160 C p.
article
8 Benzimidazole derivatives protect pancreatic β-cells against cytokine-induced apoptosis Hussain, Shafqat

160 C p.
article
9 Biosynthesis of the quinovosamycin nucleoside antibiotics diverges from that of tunicamycins by additional sugar processing genes Sumang, Felaine Anne

160 C p.
article
10 Carvacrol/thymol derivatives as highly selective BuChE inhibitors with anti-inflammatory activities: Discovery and bio-evaluation Zhang, Yuan-Lin

160 C p.
article
11 Computer aided design of CGA-N9 derived peptides based on oligopeptide transporters and their antifungal evaluations Yan, Fu

160 C p.
article
12 Design, and synthesis of 2,4-thiazolidinedione substituted 1,3,5-triazine derivatives as anti-HIV agent via inhibition of reverse transcriptase along with anti-SARS CoV-2, antibacterial and antibiofilm activity Singh, Saumya

160 C p.
article
13 Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9 Chen, Sumeng

160 C p.
article
14 Design, synthesis and biological evaluation of imine-containing inhibitors against the triple-mutant EGFR kinases based on the scaffold of osimertinib Ding, Shi

160 C p.
article
15 Design, synthesis, and evaluation of 1,4-benzodioxane-hydrazone derivatives as potential therapeutics for skin cancer: In silico, in vitro, and in vivo studies Akbar, Saleem

160 C p.
article
16 Design, synthesis and in vitro and in vivo biological evaluation of matrine derivatives as efficient anticancer agents with the characteristics of endoplasmic reticulum stress induction and apoptosis activation Wang, Xingdong

160 C p.
article
17 Design, synthesis and in vitro evaluation of non-steroidal anti-inflammatory prodrugs for osteoarthritis Voitovich, Iuliia

160 C p.
article
18 Development and evaluation of 18F-labeled novel radiopharmaceuticals for PET imaging of fibroblast activation protein expressing tumors Zhang, Qingyu

160 C p.
article
19 Development of 2- and 3-prenylated quinolines and tetrahydroquinolines with PPAR activity: From hit to lead and a novel pan-PPAR agonist as a potential candidate for metabolic syndrome Villarroel-Vicente, Carlos

160 C p.
article
20 Discovery of a novel Thiazole amide inhibitor of Inflammasome and Pyroptosis pathways Dai, Zhen

160 C p.
article
21 Discovery of naturally inspired antimicrobial peptides using deep learning Yang, Cai-Ling

160 C p.
article
22 Discovery of new 1,2,3,4-tetrahydro-β-carboline derivatives decorated with 3-N-substituted propionyl moiety flexibly bridged-chain as reactive oxygen species inducer for efficient antibacterial treatment Yang, Yike

160 C p.
article
23 Discovery of small molecule ACC inhibitors: Potential treatment for excessive sebum secretion Feng, Xilong

160 C p.
article
24 Diterpenes as nitric oxide secretion inhibitors from Kaempferia koratensis rhizomes Kongwaen, Patcharin

160 C p.
article
25 Drug repurposing of 6-AZA-UTP and itraconazole reveals novel B3GALT5 inhibitors for pancreatic cancer Botcha, Lavanya

160 C p.
article
26 Editorial Board
160 C p.
article
27 Efficient extraction of Licochalcone a with deep eutectic solvent: A promising drug for the treatment of dermatophytosis Sun, Chunlan

160 C p.
article
28 Engaging an engineered PARP-2 catalytic domain mutant to solve the complex structures harboring approved drugs for structure analyses Wang, Xiaoyu

160 C p.
article
29 Genome-guided discovery of coublibactins from Nocardia coubleae and their gallium complexes with potent antileukemic activity Tao, Qiaoqiao

160 C p.
article
30 Ginsenoside Rd and chrysophanol: Modulating the serine-glycine-one-carbon pathway to enhance neuroprotection in intracerebral hemorrhage Zhao, Xingping

160 C p.
article
31 Green synthesis of selenium nanoparticles, and its conjugation with antibacterial proteins for enhancing their antibacterial activity Mourad, Amany N.

160 C p.
article
32 Hybride nanoparticles composed of SN38-modified [12]aneN3 and biotinylated lipids for targeted and synergistic lung Cancer therapy Xu, De-Zhong

160 C p.
article
33 Identification of novel AURKA inhibitors against neuroblastoma using a virtual screening approach Yin, Hongli

160 C p.
article
34 Inhibition of FLT3-induced signalling in refractory acute myeloid leukaemia Yang, Jingmei

160 C p.
article
35 Interaction mechanisms between α-glucosidase and procyanidin dimers with different galloyl moiety: Multi-spectral analysis and molecular dynamics simulation Wang, Mengting

160 C p.
article
36 Investigation of binding mechanisms between bovine serum albumin and flutamide using multispectral techniques and molecular dynamics simulations Li, Ning

160 C p.
article
37 Issue TOC
160 C p.
article
38 2β-methoxy-2-deethoxyphantomolin synergistically enhances epirubicin effect against triple-negative breast cancer via targeted inhibition of AKT and HR pathways Gu, Jianyi

160 C p.
article
39 Neuroprotective triterpenoids from Astragalus membranaceus stems and leaves: Anti-inflammatory and anti-apoptotic mechanisms for memory improvement via in vivo and in vitro models Cheng, Yan-Gang

160 C p.
article
40 New acetamide-sulfonamide scaffolds with potential renal radiomodulatory effects: Insights into NF-κB pathway interactions Ghorab, Mostafa M.

160 C p.
article
41 New alkanesulfonate-based quinazolinone-acetohydrazide scaffolds: Rational design, synthesis, molecular docking, anticancer properties and potential EGFR and its T790M/L858R mutants inhibitors Morsy, Nagy A.

160 C p.
article
42 New steroidal saponins from Physochlainae Radix: Structures and anti-inflammatory efficacy Tan, Jin-Yan

160 C p.
article
43 Novel ALK inhibitors containing DAAP fragments: Rational drug design and anti-tumor activity research Wang, Ran

160 C p.
article
44 Novel benzofuran-conjugated indolin-2-ones as anticancer agents; design, synthesis, biological assessments, and molecular modeling insights Eldehna, Wagdy M.

160 C p.
article
45 Novel chloropyridazine sulfonamides as aromatase inhibitors and apoptotic inducers in breast cancer Zahran, Sally S.

160 C p.
article
46 Optimization of Aminoindazole derivatives as highly selective covalent inhibitors for wild-type and mutant FGFR4 Guo, Jing

160 C p.
article
47 Peptidomimetics based on thiacalixarene with L-tyrosine moieties: Antibacterial activity against methicillin-resistant Staphylococcus aureus and degradation induced by binding to α-chymotrypsin Terenteva, Olga

160 C p.
article
48 Photocaged fluorescent probes for spatiotemporally monitoring G-Quadruplex DNA in live cells Zhao, Xuzi

160 C p.
article
49 Recent advances in PROTAC-based antiviral and antibacterial therapeutics Zhou, Can

160 C p.
article
50 Redox dyshomeostasis-driven prodrug strategy for enhancing camptothecin-based chemotherapy: Selenization of SN38 as a case study Xi, Junmin

160 C p.
article
51 S-adenosylmethionine inhibits non-small cell lung cancer and enhances chemosensitivity by targeting the P62/NF-κB axis and regulating autophagy and oxidative stress Jin, Xuehang

160 C p.
article
52 Small molecule therapeutics for receptor-mediated targeting through liposomes in breast cancer treatment: A comprehensive review Ghosh, Rashmi

160 C p.
article
53 Structure-activity relationship explorations of 2-(isoxazol-5-yl)phenyl-3,4-dihydroxybenzoate derivatives to develop potent Wnt/β-catenin pathway inhibitors for colorectal cancer treatment Dong, Li

160 C p.
article
54 Synthesis and evaluation of novel amino pyrimidine derivatives containing sulfonamide and their application as EGFR inhibitors Yao, Han

160 C p.
article
55 Synthesis of new selective agents with dual anti-inflammatory and SARS-CoV-2 Mpro inhibitory activity: Antipyrine-celecoxib hybrid analogues; COX-2, COVID-19 cytokine storm and replication inhibitory activities. Abdelall, Eman K.A.

160 C p.
article
56 Synthesis of N-heterocyclic carbene‑selenium complexes modulating apoptosis and autophagy in cancer cells: Probing the interactions with biomolecules and enzymes Ashraf, Rizwan

160 C p.
article
57 Synthesis, structure activity relationship and biological evaluation of indole sulfonohydrazide derivatives as antagonists of P2Y1 and P2Y6 receptors Hameed, Abdul

160 C p.
article
58 Targeting Autotaxin with imidazole- and Triazolyl-based inhibitors: Biological insights from in vitro and in vivo studies in pulmonary fibrosis Kim, Misu

160 C p.
article
59 The development of pyridazinone-based andrographolide derivatives as anti-cancer agents with the ability of inhibiting the TFAP4/Wnt/β-catenin signaling pathway Zhang, Hang

160 C p.
article
60 The diphenylpyrimidine derivative as a novel HDAC6 inhibitor alleviates atopic dermatitis through anti-inflammatory effects facilitated via TLR4/MAPK, STAT3 and NF-κB pathways Chen, Jin-Ting

160 C p.
article
61 Unlocking the potential of novel tetrahydro-β-carboline-based HDAC6 inhibitors for colorectal cancer therapy: Design, synthesis and biological evaluation Hemida, Noreen

160 C p.
article
62 Unveiling a pyrroloindoline diketopiperazine biosynthetic pathway featuring a phytoene-synthase-like family prenyltransferase with distinct regioselectivity Duan, He

160 C p.
article
63 Unveiling the potential of xanthines, discovery of potential 7-benzyl-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione derivatives with antifibrotic activity for liver injury Mohamed, Abdalla R.

160 C p.
article
64 Whiteleg shrimp-derived Cryptides induce mitochondrial-mediated cytotoxicity in human breast Cancer El-Aal, Amr Adel Ahmed Abd

160 C p.
article
                             64 results found
 
 Koninklijke Bibliotheek - National Library of the Netherlands