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                             120 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A bifunctional naphthalimide-based fluorescent probe for imaging lysosomal peroxynitrite and viscosity in living cells and zebrafish Chen, Yiliang

154 C p.
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2 Acquiring stereospecific new pseudosugars: Obtaining rac-decahydro-1,4-epoxynaphthalene-2,3,5,6,7,8-hexaols from the Diels-Alder reaction and investigating their biological effects Aydın, Gökay

154 C p.
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3 Advances in structural identification of some thieno[2,3-d]pyrimidine scaffolds as antitumor molecules: Synthetic approaches and control programmed cancer cell death potential Mghwary, Aml E-S.

154 C p.
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4 Advances in the structural modification of Alzheimer’s disease drug – Huperzine A Zhu, Xiaoxin

154 C p.
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5 A GH1 β-glucosidase from the Fervidobacterium pennivorans DSM9078 showed extraordinary thermostability and distinctive ability in the efficient transformation of ginsenosides Zhou, Kailu

154 C p.
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6 A Glimpse for the subsistence from pandemic SARS-CoV-2 infection Rath, Santosh K.

154 C p.
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7 Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design Tahiliani, Himanshu

154 C p.
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8 An overview of phenylsulfonylfuroxan-based nitric oxide donors for cancer treatment Gao, Chao

154 C p.
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9 A Review on zerumbone and its semisynthetic Analogs: Synthesis and Implications in Medicinal chemistry Kumar, Murthi Nandha

154 C p.
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10 A self-assembled fluorescent nanoprobe recognized by FA1 site for specifically selecting HSA: Its applications in hemin detection, cell imaging and fluorescent tracing drug delivery Ding, Bo-Wen

154 C p.
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11 Beyond peptides: Unveiling the design strategies, structure activity correlations and protein-ligand interactions of small molecule inhibitors against PD-1/PD-L1 Sasmal, Pujan

154 C p.
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12 Buckyballs to fight pandemic: Water-soluble fullerene derivatives with pendant carboxylic groups emerge as a new family of promising SARS-CoV-2 inhibitors Kraevaya, Olga A.

154 C p.
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13 CDK4/6 inhibitors in HR-positive breast cancer immunotherapy Shen, Mimi

154 C p.
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14 Chemotherapeutic potential of radotinib against blood and solid tumors: A beacon of hope in drug repurposing Manoharan, Suryaa

154 C p.
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15 Coccinic acid exhibits anti-tumor efficacy against NSCLC harboring EGFR L858R/T790M mutation via the EGFR/STAT3 pathway Sun, Peiyuan

154 C p.
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16 Co, Cu, Ni, and Zn complexes of N-[(3-phenoxy phenyl)methylidene]-l-valine as α-glycosidase and α-amylase inhibitors: Synthesis, molecular docking & antimicrobial evaluation Sankar, Raji

154 C p.
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17 Comprehensive evaluation of EGFR and AKT targeting efficacy of resveratrol loaded PEGylated liposomes for the glioblastoma management: In silico, in vitro BBB permeation studies Sathishbabu, Paranthaman

154 C p.
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18 Construction of nucleus-targeted photosensitizer and highly effective photodynamic immunotherapy for cancer Liao, Yacong

154 C p.
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19 Corrigendum to “Effect of lathyrane-type diterpenoids in neural stem cell physiology: Microbial transformations, molecular docking and dynamics studies” [Bioorg. Chem. 153 (2024) 107769] Escobar-Montaño, Felipe

154 C p.
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20 Corrigendum to “Synthesis and biological evaluation of a new class of azole urea compounds as Akt inhibitors with promising anticancer activity in pancreatic cancer models” [Bioorg. Chem. 153 (2024) 107959] Pecoraro, Camilla

154 C p.
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21 Corrigendum to “The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas” [Bioorg. Chem 154 (2025) 108068] Lai, Hsuan-Yu

154 C p.
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22 Coumarin-based fluorescent probes for the detection of copper (II) and imaging in mice of Wilson’s disease Ge, Chunpo

154 C p.
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23 Current developments in PI3K-based anticancer agents: Designing strategies, biological activity, selectivity, structure-activity correlation, and docking insight Ashadul Sk, Md.

154 C p.
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24 Damsin and neoambrosin: Two sesquiterpene lactones with affinity and different activity for PPAR and TRPA1 receptors Abdel-dayem, Shymaa I.A.

154 C p.
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25 Derivatives of D(−)-glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-III: Synthesis, biological screening and in silico binding interaction analysis Das, Sanjib

154 C p.
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26 Design and optimization strategies of PROTACs and its Application, Comparisons to other targeted protein degradation for multiple oncology therapies Malarvannan, M

154 C p.
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27 Design and synthesis of JNK1-targeted PROTACs and research on the activity Guo, Yue

154 C p.
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28 Design, synthesis and activity evaluation of reduction-responsive anticancer peptide temporin-1CEa drug conjugates Han, Zhenbin

154 C p.
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29 Design, synthesis and anticancer evaluation of 4-Substituted 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines as dual topoisomerase I and II inhibitors Arora, Sahil

154 C p.
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30 Design, synthesis, and biological evaluation of novel 3-naphthylthiophene derivatives as potent SIRT2 inhibitors for the treatment of myocardial fibrosis Zhang, Zhuo

154 C p.
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31 Design, synthesis and biological evaluation of novel pyrazolinone derivatives as multifunctional ligands for the treatment of Alzheimer’s disease Wang, Huabo

154 C p.
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32 Design, synthesis and biological evaluation of truncated 1′-homologated 4′-selenonucleosides as PPARγ/δ dual modulators Choi, Hongseok

154 C p.
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33 Design, synthesis, and evaluation of quinolin-2(1H)-ones as PDE1 inhibitors for the treatment of inflammatory bowel disease Zhou, Qian

154 C p.
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34 Design, synthesis, and molecular docking of 4‑Thiol‑N‑acetylhexosamine uridine diphosphate donors for glycan synthesis Zheng, Jie

154 C p.
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35 Design, synthesis, biological evaluation and multi spectroscopic studies of novel 2-styrylquinoline-carboxamide derivatives as potential DNA intercalating anticancer agents Omidkhah, Negar

154 C p.
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36 Design, synthesis, biological evaluations and in silico studies of (Z)-2-(2,4-dioxothiazolidin-5-ylidene)methyl)-2-ethoxyphenyl-alkyl/arylsulfonates as potential α-glucosidase inhibitors Dahiya, Lalita

154 C p.
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37 Development of novel tetrazole-based pyruvate kinase M2 inhibitors targeting U87MG glioblastoma cells Chowdhury, Moumita Ghosh

154 C p.
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38 Development of pyrimidone derivatives as nonpeptidic and noncovalent 3-chymotrypsin-like protease (3CLpro) inhibitors with anti-coronavirus activities Pan, Fan

154 C p.
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39 Discovery and synthesis of novel phenoxyacetate ester Schiff base α-glucosidase inhibitors Fan, Zeng Yi

154 C p.
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40 Discovery of a new eugenol-benznidazole hybrid active against different evolutive stages of Trypanosoma cruzi de Melo, Ígor Matheus

154 C p.
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41 Discovery of a novel CDK4/6 and HDAC dual-targeting agent for the treatment of hepatocellular carcinoma Niu, Zizhou

154 C p.
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42 Discovery of an theranostic functional mAb for visualizing the sensitivity and effectiveness of PD-L1 checkpoint therapy Wang, Jin

154 C p.
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43 Discovery of cyanidin-3-O-galactoside as a novel CNT2 inhibitor for the treatment of hyperuricemia Zheng, Fengxin

154 C p.
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44 Discovery of marine ent-eudesmane sesquiterpenoids as angiogenic inhibitors via suppressing VEGF-A/VEGFR2 signaling pathway Li, Wan-Shan

154 C p.
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45 Discovery of novel oxindole derivatives as TRPA1 antagonists with potent analgesic activity for pain treatment Qi, Yiming

154 C p.
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46 Discovery of pentacyclic triterpene conjugates as HBV polymerase/NTCP dual-targeting inhibitors with potent anti-HBV activities Chen, Yixin

154 C p.
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47 Discovery of thioetomidate derivatives as rapid recovery hypnotics without adrenocortical suppression Zhu, Jin

154 C p.
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48 Diversity-oriented synthesis of second generation guanidinium-rich transporters toward cell-selective penetration Nguyen, Duc Tai

154 C p.
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49 Editorial Board
154 C p.
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50 Electron-rich anilines as cleavable linkers for peptides Watts, Andrew M.

154 C p.
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51 Enzyme fragment complementation driven by nucleic acid hybridization sans self-labeling protein Xu, Zihan

154 C p.
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52 Epidermal growth factor receptor mutations in breast Cancer: Therapeutic challenges and way forward Shetty, Swathi R.

154 C p.
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53 Exploring a novel thiazole derivatives hybrid with fluorinated-indenoquinoxaline as dual inhibitors targeting VEGFR2/AKT and apoptosis inducers against hepatocellular carcinoma with docking simulation Abusaif, Moustafa S.

154 C p.
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54 Exploring the efficacy of Wenshentiaojing decoction in PCOS: Network pharmacology and mouse model insights Wang, Mingming

154 C p.
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55 Fatty acid chain modification enhances the serum stability of antimicrobial peptide B1 and activities against Staphylococcus aureus and Klebsiella pneumoniae Liao, Zhouyuji

154 C p.
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56 First-generation high-affinity ST14 radiopharmaceutical: Design, synthesis, and preclinical PET imaging evaluation for pancreatic cancer detection Peng, Tukang

154 C p.
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57 Further transformation of fungal catalyzed transformed metabolite 11β-hydroxy-dianabol into new aromatase inhibitors Aamer, Muhammad

154 C p.
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58 Genome mining of nonenzymatic ortho-quinone methide-based pseudonatural products from ascidian-derived fungus Diaporthe sp.SYSU-MS4722 Ren, Shuya

154 C p.
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59 Highly oxygenated ent-abietane diterpenoid lactones from Euphorbia peplus and their anti-inflammatory activity Yan, Ying

154 C p.
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60 Hydrazone copper(II) complexes suppressed lung adenocarcinoma by activating multiple anticancer pathway Li, Aili

154 C p.
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61 Hypoglycemic activity and metabolite diversity of Archangium sp. UTMC 4535 with the first report on magnodelavin biosynthesis by bacteria Saadatpour, Fatemeh

154 C p.
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62 Identification and validation of WDR5 WIN-site ligands via DNA-encoded chemical library screening Ding, Baoli

154 C p.
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63 Indoles as promising Therapeutics: A review of recent drug discovery efforts Pravin, Naik Jui

154 C p.
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64 In vitro and in vivo evaluation of novel ursolic acid derivatives as potential antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) Sun, Ying

154 C p.
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65 In vivo, in vitro, and in silico approaches in the detailed study of di-butyl phthalate (DBP), a plasticizer-induced lung fibrosis via Nrf-2/Keap-1/HO-1 pathway and its regulation Singh, Payal

154 C p.
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66 Issue TOC
154 C p.
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67 KAHA ligation as a platform for the rapid discovery of Protein Tyrosine phosphatase 1B (PTP1B) inhibitors Tian, Jing

154 C p.
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68 Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain Mei, Yuheng

154 C p.
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69 Metabolomic fingerprinting, molecular modelling and experimental bioprospection of Helianthus annuus seed cultivars as Pseudomonas aeruginosa LasR modulators Raghoonanadan, Akshay

154 C p.
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70 Mining of antioxidant sesquiterpene lactones from the aerial parts of Saussurea involucrata with feature-based molecular network strategy Zhang, Bodou

154 C p.
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71 Multifunctional porphyrin-substituted phenylalanine–phenylalanine nanoparticles for diagnostic and therapeutic applications in Alzheimer’s disease Xia, Ning

154 C p.
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72 Multi-target directed ligands inspired natural products as an effective approach for the treatment of complex chronic health disorders Shaaban, Amira E.

154 C p.
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73 Multivalent chitobiose self-assembled glycostructures as ligands to lysozyme Patel, Bharat Singh

154 C p.
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74 Novel aryl (dithioglycosyl)methane derivatives as anti-proliferative agents Rana, Abhijit

154 C p.
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75 Novel dual-channel ratiometric fluorescence probe for SO2 detection in food and bioimaging applications based on FRET mechanism Li, Shufei

154 C p.
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76 Novel methyldithiocarbazate derivatives as NDM-1 inhibitors to combat multidrug-resistant bacterial infection with β-lactams Wang, Nan

154 C p.
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77 Organic Chemistry-Biology interface research activities in India Dandela, Rambabu

154 C p.
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78 Oxidation of myrtenol to myrtenal epoxide in a porphyrin-based photocatalytic system – A novel terpene alcohol derivative with antimicrobial and anticancer properties Kutyła, Mateusz

154 C p.
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79 Pharmacological investigation of selected 1,2,4 triazole derivative against ethanol induced gastric ulcer Azam, Jawad

154 C p.
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80 Photoresponsive nitric oxide photocage/photodynamic integrated prodrug for advanced management of drug-resistant bacteria-infected wound therapy Lin, Jingjing

154 C p.
artikel
81 Physalins and neophysalins from the calyx of Physalis alkekengi: Structures and anti-inflammatory efficacy Zhang, Zhao-Xin

154 C p.
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82 Picrotoxane-type sesquiterpenoids from Dendrobium improve insulin resistance and increase glucose-stimulated insulin secretion Li, Han-Fen

154 C p.
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83 Podocarpane and cleistanthane diterpenoids from Strophioblachia glandulosa: structural elucidation, anti-hypertrophy activity and network pharmacology Wu, Xue-Wen

154 C p.
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84 Protein arginine methyltransferase 7 modulators in disease therapy: Current progress and emerged opportunity Yu, Dongmin

154 C p.
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85 Quinazoline derivatives as novel bacterial sphingomyelinase enzyme inhibitors Ozturk, Ozge Kuyrukcu

154 C p.
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86 Ramifloraolides A − D, four highly oxygenated picrotoxane-type sesquiterpenoids from the stems of Baccaurea ramiflora and their antithrombotic activity Su, Li-Hua

154 C p.
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87 Rational design and syntheses of naphthalimide-based fluorescent probes for targeted detection of diabetes biomarkers Roy, Sanjukta

154 C p.
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88 Rational design, synthesis and computational studies of multi-targeted anti-Alzheimer’s agents integrating coumarin scaffold Abd El-Mageed, Menna M.A.

154 C p.
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89 Rational design, synthesis, biological evaluation, molecular docking, and molecular dynamics of substituted uracil derivatives as potent anti-cancer agents Basiony, Ebtessam A.

154 C p.
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90 Recent advancements in mechanistic research, therapeutic potential, and structure-activity relationships of aurora kinase inhibitors in cancer therapies Teli, Ghanshyam

154 C p.
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91 Recent Advances in enhancer of zeste homolog 2 Inhibitors: Structural insights and therapeutic applications Cao, Ruolin

154 C p.
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92 Revealing 5-(3,5-difluorobenzyl)-1H-indazole as the active pharmacophore of ALK/ROS1 dual inhibitors through theoretical calculations and biological activity evaluations Huang, Xiaoling

154 C p.
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93 S-Alkylated sulfonium betulin derivatives: Synthesis, antibacterial activities, and wound healing applications Deng, Yiding

154 C p.
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94 Shedding light on imaging cancer research: Design and synthesis of 1, 8-naphthalimide-based PRMT5-targeted fluorescent ligands Ali Shah, Sayed Asmat

154 C p.
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95 Structurally diverse meroterpenoids from Arnebia euchroma and their anti-inflammatory effects through NF-κB pathway Shi, Xiaojing

154 C p.
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96 Structure activity relationship for anticancer activities of spirooxindole derivatives: A comprehensive review Pradhan, Gandhar

154 C p.
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97 Synthesis and bioevaluation of a new 68Ga-labelled niraparib derivative that targets PARP-1 for tumour imaging Wang, Qianna

154 C p.
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98 Synthesis and biological assessment of benzimidazole-acrylonitrile-1,2,3-triazole derivatives as α-glucosidase inhibitors Hatamfayazi, Mahdi

154 C p.
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99 Synthesis and characterization of a novel Naphthalimide-Selenium based Temozolomide drug conjugate in glioma cells Sharma, Shalini

154 C p.
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100 Synthesis and in vitro leishmanicidal activity of novel N-arylspermidine derivatives Mollo, María C.

154 C p.
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101 Synthesis, Characterization, and antiviral evaluation of New Chalcone-Based Imidazo[1,2-a]pyridine Derivatives: Insights from in vitro and in silico Anti-HIV studies Azzouzi, Mohamed

154 C p.
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102 Synthesis, in vivo evaluation, and in silico molecular docking of benzo[h]quinoline derivatives as potential Culex pipiens L. larvicides Ramadan, Sayed K.

154 C p.
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103 Synthesis of novel imino-coumarin and acrylonitrile 2-benzazole hybrids as potent anticancer agents targeting tubulin Pavlinac, Ida Boček

154 C p.
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104 Synthesis of novel pyrimidine-based Schiff base complexes: Targeting Amyloid-β aggregation in Alzheimer’s disease İrişli, Sevil

154 C p.
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105 Synthesis of novel spiroisoxazolidino hybrids of alantolactone and isoalantolactone via 1,3 dipolar nitrone cycloaddition and its antimicrobial Evaluation Tabassum, Aliya

154 C p.
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106 Synthesis, X-ray, antioxidant, in-vitro biological & in-silico docking studies of novel organoselenides: Promising colorectal cancer inhibitors Thakur, Shalu

154 C p.
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107 Targeted isolation of diketopiperazines from a deep-sea derived fungus with anti-neuroinflammatory effects Wu, Jingshuai

154 C p.
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108 Targeting XPO1 for fighting relapsed/refractory diseases: The research progress of XPO1 inhibitors Li, Ye-Qin

154 C p.
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109 TDP1 represents a promising therapeutic target for overcoming tumor resistance to chemotherapeutic agents: progress and potential Zhang, Meimei

154 C p.
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110 The first attempt in synthesis, identification, and evaluation of SEPT9 inhibitors on human oral squamous carcinomas Lai, Hsuan-Yu

154 C p.
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111 The role of DDR1 in cancer and the progress of its selective inhibitors Wang, Jianjun

154 C p.
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112 Thiazole – A promising scaffold for antituberculosis agents and structure–activity relationships studies Zhao, Xuanming

154 C p.
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113 Topical application of magnolol ameliorates psoriasis-like dermatitis by inhibiting NLRP3/Caspase-1 pathway and regulating tryptophan metabolism Chen, Yi

154 C p.
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114 Trametinib and M17, a novel small molecule inhibitor of AKT, display a synergistic antitumor effect in triple negative breast cancer cells through the AKT/mTOR and MEK/ERK pathways Han, Hongwei

154 C p.
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115 Trifluoromethylcinnamanilides – Effective dual inhibitors of Mycobacterium smegmatis and Plasmodium falciparum Kos, Jiri

154 C p.
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116 2-Trifluoromethyl-2H-chromene ethers: The dual triumph of anti-inflammation and analgesia with minimal ulcer threat Cai, Nan

154 C p.
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117 Trolox derivatives: Synthesis, structure–activity relationship and promote wound healing by regulating oxidative stress and inflammation Zhao, Jie

154 C p.
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118 Tryptanthrins as multi-bioactive agents: discovery, diversity distribution and synthesis Alam, Khorshed

154 C p.
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119 Unveiling the potential anticancer activity of new dihydropyrimidines through dual inhibition of EGFR and TrkA: Design, synthesis, and in silico study Slly, Aya M.

154 C p.
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120 X-ray induced in-situ ferroptosis through the Fenton reaction of iron supplements for the cancer therapy Qian, Wang

154 C p.
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                             120 gevonden resultaten
 
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