| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 2: Non-DSM compounds
|
Sharma, Manmohan
|
|
|
153 |
C |
p.
|
artikel
|
| 2 |
A dual-state emission luminogen for lipid droplet imaging and photodynamic therapy
|
Lei, Yu
|
|
|
153 |
C |
p.
|
artikel
|
| 3 |
Advances in designing ternary complexes: Integrating in-silico and biochemical methods for PROTAC optimisation in target protein degradation
|
Shaik, Shareef
|
|
|
153 |
C |
p.
|
artikel
|
| 4 |
Advances in drug discovery of flavivirus NS2B-NS3pro serine protease inhibitors for the treatment of Dengue, Zika, and West Nile viruses
|
João, Emílio Emílio
|
|
|
153 |
C |
p.
|
artikel
|
| 5 |
A FRET probe based on flavonol-benzothiazole for the detection of viscosity and SO2 derivatives
|
Xiao, Wei
|
|
|
153 |
C |
p.
|
artikel
|
| 6 |
A mini review of supramolecular antagonists based on macrocyclic host compounds
|
Li, Shanshan
|
|
|
153 |
C |
p.
|
artikel
|
| 7 |
2-Aminobenzothiazole based adjuvant of polymyxin E against Gram-negative bacteria
|
Chen, Yuce
|
|
|
153 |
C |
p.
|
artikel
|
| 8 |
Amino polycarboxylic acids-modified abiraterone derivatives as potential injectable anti-prostate cancer agents
|
Zhu, Na
|
|
|
153 |
C |
p.
|
artikel
|
| 9 |
Analysis of the effects of differently charged peptides on α-amylase and their interaction mechanisms
|
Yang, Xiaoyu
|
|
|
153 |
C |
p.
|
artikel
|
| 10 |
An intramolecular charge transfer based fluorescent probe for imaging of OCl–
|
Sun, Shu-tao
|
|
|
153 |
C |
p.
|
artikel
|
| 11 |
A NIR fluorescent probe based on tricyanofuran for the detection of β-galactosidase in living ovarian tumor cells and in vivo
|
Jiang, Wen
|
|
|
153 |
C |
p.
|
artikel
|
| 12 |
Antibacterial and antibiofilm agents in the group of xanthone derivatives with piperazine moiety active against drug-resistant Helicobacter pylori strains
|
Żelaszczyk, Dorota
|
|
|
153 |
C |
p.
|
artikel
|
| 13 |
Anticancer and Antibacterial Activeness of Fused Pyrimidines: Newfangled Updates
|
Bhatnagar, Ayushi
|
|
|
153 |
C |
p.
|
artikel
|
| 14 |
Anticancer and anti-inflammatory effects of novel ethyl pyrazole derivatives having sulfonamide terminal moiety
|
Abdel-Maksoud, Mohammed S.
|
|
|
153 |
C |
p.
|
artikel
|
| 15 |
Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis
|
Hu, Xin-Yue
|
|
|
153 |
C |
p.
|
artikel
|
| 16 |
Apigenin analogs as α-glucosidase inhibitors: Molecular docking, biochemical, enzyme kinetic, and an in vivo mouse model study
|
Liu, Honghui
|
|
|
153 |
C |
p.
|
artikel
|
| 17 |
A potent Bioorganic azapodophyllotoxin derivative Suppresses tumor Progression in Triple negative breast Cancer: An Insight into its Inhibitory effect on tubulin polymerization and Disruptive effect on microtubule assembly
|
Gupta, Smruti
|
|
|
153 |
C |
p.
|
artikel
|
| 18 |
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress
|
Li, Yue
|
|
|
153 |
C |
p.
|
artikel
|
| 19 |
Benzylpiperidine derivatives as new dual μ-opioid and σ1 receptor ligands with potent antinociceptive effects
|
Li, Zong-Zheng
|
|
|
153 |
C |
p.
|
artikel
|
| 20 |
Biologically active franchetine-type diterpenoid alkaloids: Isolation, synthesis, anti-inflammatory, agalgesic activities, and molecular docking
|
Xiao, Yan
|
|
|
153 |
C |
p.
|
artikel
|
| 21 |
Biosynthesis of plant-derived triterpenoid asiatic acid in Saccharomyces cerevisiae cell factories
|
Lian, Yuhan
|
|
|
153 |
C |
p.
|
artikel
|
| 22 |
Butanolides and clerodane diterpenes from the twigs of Casearia grewiifolia and their effects on adiponectin secretion
|
Nhoek, Piseth
|
|
|
153 |
C |
p.
|
artikel
|
| 23 |
Cannabinoid receptor 2 (CB2) modulators: A patent review (2016–2024)
|
Naikoo, Rayees Ahmad
|
|
|
153 |
C |
p.
|
artikel
|
| 24 |
Chemo-enzymatic synthesis of NPN cofactor taking advantage of ADP-ribosyl cyclase and LarC cyclometallase promiscuous activities
|
Vucko, Timothé
|
|
|
153 |
C |
p.
|
artikel
|
| 25 |
Chlorine containing tetrahydropyrimidines: Synthesis, characterization, anticancer activity and mechanism of action
|
Milović, Emilija
|
|
|
153 |
C |
p.
|
artikel
|
| 26 |
Cholenamide-based, antiviral fluorescent probes targeting oxysterol-binding protein
|
Nigro, Fatima
|
|
|
153 |
C |
p.
|
artikel
|
| 27 |
Chromene-based compounds as drug candidates for renal and bladder cancer therapy – A systematic review
|
Costa Cerqueira, Mónica
|
|
|
153 |
C |
p.
|
artikel
|
| 28 |
Clinical and preclinical advances in PSMA-Directed Antibody-Drug conjugates (ADCs): Current status and hope for the future
|
Mirzaei, Yousef
|
|
|
153 |
C |
p.
|
artikel
|
| 29 |
Clinical applications of small-molecule GABAAR modulators for neurological disorders
|
Chen, Guangyong
|
|
|
153 |
C |
p.
|
artikel
|
| 30 |
Co-based carbon material as CYP3A4-like nanozyme with both biocatalytic activity and inhibition behaviors
|
Wu, Dong
|
|
|
153 |
C |
p.
|
artikel
|
| 31 |
Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids
|
Othman, Shimaa A.
|
|
|
153 |
C |
p.
|
artikel
|
| 32 |
Combretastatin A-4 based compounds as potential anticancer agents: A review
|
Omar, Mai H.
|
|
|
153 |
C |
p.
|
artikel
|
| 33 |
Comprehensive utilization of in silico approach and in vitro experiment to unveil the molecular mechanisms of mono (2-ethylhexyl) phthalate-induced lung adenocarcinoma
|
Wang, Wenwen
|
|
|
153 |
C |
p.
|
artikel
|
| 34 |
Computational Design, Synthesis, and Bioevaluation of 2-(Pyrimidin-4-yl) oxazole-4-carboxamide Derivatives: Dual Inhibition of EGFRWT and EGFRT790M with ADMET Profiling
|
Raghunath Khedkar, Nilesh
|
|
|
153 |
C |
p.
|
artikel
|
| 35 |
Copper(II) aromatic heterocyclic complexes of Gatifloxacin with multi-targeting capabilities for antibacterial therapy and combating antibiotic resistance
|
Wu, Xiao-Yin
|
|
|
153 |
C |
p.
|
artikel
|
| 36 |
Cordycepin alleviates diabetes mellitus-associated hepatic fibrosis by inhibiting SOX9-mediated Wnt/β-catenin signal axis
|
Chen, Shuang
|
|
|
153 |
C |
p.
|
artikel
|
| 37 |
Corrigendum to “Discovery of neuroprotective agents: Potent, brain penetrating, lipoic acid derivatives for the potential treatment of ischemic stroke by regulating oxidative stress and inflammation – A preliminary study” [Bioorg. Chem. 147 (2024) 107339]
|
Zhu, Chenchen
|
|
|
153 |
C |
p.
|
artikel
|
| 38 |
Corrigendum to “Heterocycle-functional steroidal derivatives: Design, synthesis, bioevaluation and SARs of steroidal pyrazolo[1,5-a]pyrimidines as potential ALK inhibitors” [Bioorg. Chem. 153 (2024) 107847]
|
Liu, Fang
|
|
|
153 |
C |
p.
|
artikel
|
| 39 |
Corrigendum to “Synthesis and broad-spectrum biocidal effect of novel gemini quaternary ammonium compounds” [Bioorg Chem. 151 (2024) 107646]
|
Zivna, Natalie
|
|
|
153 |
C |
p.
|
artikel
|
| 40 |
Coumarin-imidazopyridine hybrids and their first-in-class ZnII metal complexes as potent dual entry and replication inhibitors of Zika viral infection
|
Jefferson de Arruda, Henrique
|
|
|
153 |
C |
p.
|
artikel
|
| 41 |
Curcumol derivatives exhibit ameliorating effects on lipopolysaccharide-induced acute lung injury: Synthesis, biological evaluation, structure–activity relationship and action mechanism
|
Li, Gen
|
|
|
153 |
C |
p.
|
artikel
|
| 42 |
Deciphering substrate promiscuity and specificity of indolethylamine N-methyltransferase family enzymes from amphibian toads
|
Zhang, An-An
|
|
|
153 |
C |
p.
|
artikel
|
| 43 |
Design and synthesis of novel mitochondria-targeted ergosterol peroxide derivatives as potential anti-cancer agents
|
Wang, Lu
|
|
|
153 |
C |
p.
|
artikel
|
| 44 |
Design, green synthesis, and anti-glutamate damage screening of chalcone derivatives with spiro-heterocyclic structures as potential anti-ischemic brain and eye damage agents
|
Wu, Jianzhang
|
|
|
153 |
C |
p.
|
artikel
|
| 45 |
Design, synthesis, and antiproliferative activity evaluation of novel α-mangostin derivatives by ROS/MAPK signaling pathway
|
Fredimoses, Mangaladoss
|
|
|
153 |
C |
p.
|
artikel
|
| 46 |
Design, synthesis, and antitumor activity evaluation of 1,2,3-triazole derivatives as potent PD-1/PD-L1 inhibitors
|
Xia, Yu
|
|
|
153 |
C |
p.
|
artikel
|
| 47 |
Design, synthesis and bioactivity evaluation of triazole antifungal drugs with phenylthiophene structure
|
Wu, Xudong
|
|
|
153 |
C |
p.
|
artikel
|
| 48 |
Design, synthesis, and biological evaluation of adenosine derivatives targeting DOT1L and HAT as anti-leukemia agents
|
Sethy, Bidyadhar
|
|
|
153 |
C |
p.
|
artikel
|
| 49 |
Design, synthesis, and biological evaluation of novel AAK1/HDACs dual inhibitors against SARS-CoV-2 entry
|
Mao, Nian-Dong
|
|
|
153 |
C |
p.
|
artikel
|
| 50 |
Design, synthesis, and biological evaluation of novel (E)-2-cyano-3-(4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-2-yl) derivatives as potent STAT3-targeting anticolorectal cancer agents
|
Jiang, Weiqing
|
|
|
153 |
C |
p.
|
artikel
|
| 51 |
Design, synthesis, and biological evaluation of novel HPK1 inhibitors possessing 3-cyano-quinoline moiety
|
Chen, Long
|
|
|
153 |
C |
p.
|
artikel
|
| 52 |
Design, synthesis, and biological evaluation of novel 5,7,4′-trimethoxyflavone sulfonamide-based derivatives as highly potent inhibitors of LRPPRC/STAT3/CDK1
|
Wu, Rui
|
|
|
153 |
C |
p.
|
artikel
|
| 53 |
Design, synthesis and biological evaluation of prostate-specific membrane antigen (PSMA)-targeted SIRT2 inhibitors
|
Yu, Junhui
|
|
|
153 |
C |
p.
|
artikel
|
| 54 |
Design, synthesis, and biological evaluation of tetrahydropyrimidine analogue as GSK-3β/Aβ aggregation inhibitor and anti-Alzheimer’s agent
|
Sukanya, Sukanya
|
|
|
153 |
C |
p.
|
artikel
|
| 55 |
Design, synthesis, and evaluation of dual son of sevenless 1 (SOS1) and epidermal growth factor receptor (EGFR) inhibitors for the treatment of cancers
|
Zeng, Yi
|
|
|
153 |
C |
p.
|
artikel
|
| 56 |
Design, synthesis and FXR partial agonistic activity of anthranilic acid derivatives bearing aryloxy moiety as therapeutic agents for metabolic dysfunction-associated steatohepatitis
|
Chen, Cong
|
|
|
153 |
C |
p.
|
artikel
|
| 57 |
Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors
|
Eldehna, Wagdy M.
|
|
|
153 |
C |
p.
|
artikel
|
| 58 |
Design, synthesis and optimization of pyrazolo[3,4-b] pyridine derivatives as Hsp110-STAT3 interaction disruptors for the treatment of pulmonary arterial hypertension
|
Li, Mengqi
|
|
|
153 |
C |
p.
|
artikel
|
| 59 |
Design, synthesis, and structure–activity relationships of xanthine derivatives as broad-spectrum inhibitors of coronavirus replication
|
Chen, Xiaofang
|
|
|
153 |
C |
p.
|
artikel
|
| 60 |
Design, synthesis, biological evaluation study of spirocyclic POM analogues as novel MmpL3 anti-tubercular agent
|
Mi Kim, Young
|
|
|
153 |
C |
p.
|
artikel
|
| 61 |
Design, synthesis, molecular docking, and evaluation of sulfonyl quinazoline analogues as promising liver cancer drugs
|
Venkatesan, Gopalakrishnan
|
|
|
153 |
C |
p.
|
artikel
|
| 62 |
Design, synthesis, molecular modeling and evaluation of 2,4-diaminopyrimidine analogues as promising colorectal cancer drugs
|
Venkatesan, Gopalakrishnan
|
|
|
153 |
C |
p.
|
artikel
|
| 63 |
Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer
|
Badawi, Waleed A.
|
|
|
153 |
C |
p.
|
artikel
|
| 64 |
Development and preclinical evaluation of a cyclic PET tracer targeting integrin-α6 on colorectal cancer models
|
Chen, Liping
|
|
|
153 |
C |
p.
|
artikel
|
| 65 |
Development of an at-line coupling of LC-QTOF-ESI-MS/MS to steroid 5-alpha reductase inhibition assay, a fast bioactive targeting and guided purification of natural complex sample, Impatiens balsamina Linn.
|
Srivilai, Jukkarin
|
|
|
153 |
C |
p.
|
artikel
|
| 66 |
Development of natural product-based targeted protein degraders as anticancer agents
|
Chen, Cheng
|
|
|
153 |
C |
p.
|
artikel
|
| 67 |
Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interaction
|
Elgohary, Mohamed K.
|
|
|
153 |
C |
p.
|
artikel
|
| 68 |
Development of novel aza-stilbenes as a new class of selective MAO-B inhibitors for the treatment of Parkinson’s disease
|
Knez, Damijan
|
|
|
153 |
C |
p.
|
artikel
|
| 69 |
Development of novel imipridone derivatives with potent anti-cancer activities as human caseinolytic peptidase P (hClpP) activators
|
Zhang, Yanzhi
|
|
|
153 |
C |
p.
|
artikel
|
| 70 |
Disclosing novel melanogenesis pathways: Formation of unexpected biphenyl-type dimers through radical–radical coupling by solid-state oxidation of the melanin biosynthetic precursor 5,6-dihydroxyindole
|
Viggiano, Sara
|
|
|
153 |
C |
p.
|
artikel
|
| 71 |
Discovery and optimization of novel 4-morpholinothieno[3,2-d]pyrimidine derivatives as potent BET inhibitors for cancer therapy
|
Ran, Kai
|
|
|
153 |
C |
p.
|
artikel
|
| 72 |
Discovery and structure − activity relationships of 2,4,5-trimethoxyphenyl pyrimidine derivatives as selective D5 receptor partial agonists
|
Kumar, Sakesh
|
|
|
153 |
C |
p.
|
artikel
|
| 73 |
Discovery and synthesis of novel glyrrhizin-analogs containing furanoylpiperazine and the activity against myocardial injury in sepsis
|
Li, Wei
|
|
|
153 |
C |
p.
|
artikel
|
| 74 |
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
|
Nie, Hui-Jun
|
|
|
153 |
C |
p.
|
artikel
|
| 75 |
Discovery of Daclatasvir as a potential PD-L1 inhibitor from drug repurposing
|
Sun, Mengmeng
|
|
|
153 |
C |
p.
|
artikel
|
| 76 |
Discovery of ent-kaurane diterpenoid glucosides as potent analgesics from the leaves of Pieris formosa
|
Feng, Yuanyuan
|
|
|
153 |
C |
p.
|
artikel
|
| 77 |
Discovery of epigenetic modulators targeting HDACs and EZH2 simultaneously for the treatment of hematological malignancies
|
Zhang, Jinwei
|
|
|
153 |
C |
p.
|
artikel
|
| 78 |
Discovery of flavonoid-containing compound Lupalbigenin as anti-NSCLC cancer agents via suppression of EGFR and ERK1/2 pathway
|
Cuan, Xiangdan
|
|
|
153 |
C |
p.
|
artikel
|
| 79 |
Discovery of N-Benzylpiperidinol derivatives as USP7 inhibitors against Hematology
|
Pan, Youlu
|
|
|
153 |
C |
p.
|
artikel
|
| 80 |
Discovery of new 4-aminoquinoline derivatives containing an amine or hydroxamic acid terminal as multifunctional agents for the treatment of Alzheimer’s disease
|
Zhai, Bochao
|
|
|
153 |
C |
p.
|
artikel
|
| 81 |
Discovery of new molecular hybrid derivatives with coumarin scaffold bearing pyrazole/oxadiazole moieties: Molecular docking, POM analyses, in silico pharmacokinetics and in vitro antimicrobial evaluation with identification of potent antitumor pharmacophore sites
|
Tataringa, Gabriela
|
|
|
153 |
C |
p.
|
artikel
|
| 82 |
Discovery of novel and potent sulfonamide derivatives as orally available drug for psoriasis
|
Qi, Liang
|
|
|
153 |
C |
p.
|
artikel
|
| 83 |
Discovery of novel diaryl urea-oxindole hybrids as BRAF kinase inhibitors targeting BRAF and KRAS mutant cancers
|
Ghannam, Iman A.Y.
|
|
|
153 |
C |
p.
|
artikel
|
| 84 |
Discovery of novel Macrocyclic small molecules Based on 2-Amino-4-thiazolylpyridineas selective EGFR inhibitors with high Blood-Brain barrier penetration for the treatment of glioblastoma
|
Wu, Guowu
|
|
|
153 |
C |
p.
|
artikel
|
| 85 |
Discovery of novel 5-phenyl-1H-pyrrole-2-carboxylic acids as Keap1-Nrf2 inhibitors for acute lung injury treatment
|
Tang, Jiaqin
|
|
|
153 |
C |
p.
|
artikel
|
| 86 |
Discovery of novel 20S proteasome subunit β5 PROTAC degraders as potential therapeutics for pharyngeal carcinoma and Bortezomib-resistant multiple myeloma
|
Wang, Shumei
|
|
|
153 |
C |
p.
|
artikel
|
| 87 |
Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC)
|
Li, Yuying
|
|
|
153 |
C |
p.
|
artikel
|
| 88 |
Discovery of the FXR/CES2 dual modulator LE-77 for the treatment of irinotecan-induced delayed diarrhea
|
Cao, Zhijun
|
|
|
153 |
C |
p.
|
artikel
|
| 89 |
DNA and hemoglobin binding activities: Investigation of coumarin-thiosemicarbazone hybrids
|
Çelik, Esra
|
|
|
153 |
C |
p.
|
artikel
|
| 90 |
Eco-conscious synthesis of novel 1,2,4-triazolo[1,5-a]pyrimidine derivatives as potent Anti-microbial agent and comparative study of cell viability and cytotoxicity in HEK-293 cell line utilizingIndian gooseberry (Phyllanthus emblica) fruit extract
|
Bhatt, Bhaktiben R.
|
|
|
153 |
C |
p.
|
artikel
|
| 91 |
Editorial Board
|
|
|
|
153 |
C |
p.
|
artikel
|
| 92 |
Effect of lathyrane-type diterpenoids in neural stem cell physiology: Microbial transformations, molecular docking and dynamics studies
|
Escobar-Montaño, Felipe
|
|
|
153 |
C |
p.
|
artikel
|
| 93 |
Enabling oral novel Taxanes-based Chemotherapy with Lipophilic prodrug Self-nanoemulsifying drug delivery system
|
Miao, Yifan
|
|
|
153 |
C |
p.
|
artikel
|
| 94 |
Enhancing rhamnolipid production via immobilized Pseudomonas stutzeri lipase: A comparative study
|
Cruz, Guillermo
|
|
|
153 |
C |
p.
|
artikel
|
| 95 |
Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa
|
Fihn, Conrad A.
|
|
|
153 |
C |
p.
|
artikel
|
| 96 |
Evaluation of the antifungal activity of novel bis-pyrazole carboxamide derivatives and preliminary investigation of the mechanism
|
Song, Yaping
|
|
|
153 |
C |
p.
|
artikel
|
| 97 |
Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide
|
Cao, Jun
|
|
|
153 |
C |
p.
|
artikel
|
| 98 |
Exploring the antifungal potential of novel carbazate derivatives as promising drug candidates against emerging superbug, Candida auris
|
Fatima, Tazeen
|
|
|
153 |
C |
p.
|
artikel
|
| 99 |
Exploring the selective incorporation of 15β-senecioyloxi-ent-kaurenoic acid methyl ester in Langmuir monolayers mimicking cell membranes
|
da Silva, Gustavo H.O.
|
|
|
153 |
C |
p.
|
artikel
|
| 100 |
Expression of PPAR-γ TF by newly synthesized thiazolidine-2,4-diones to manage glycemic control: Insights from in silico, in vitro and experimental pharmacology in wistar rats
|
Gharge, Shankar
|
|
|
153 |
C |
p.
|
artikel
|
| 101 |
Facile constructed meroterpenoids with novel hexadecahydroacephenanthrylene carbon skeleton using the biotransformation and chemical synthesis method
|
Yan, Die
|
|
|
153 |
C |
p.
|
artikel
|
| 102 |
Filicinic acid based meroterpenoids from Hypericum elodeoides and their anti-Alzheimer’s disease effects
|
Li, Jing-Dian
|
|
|
153 |
C |
p.
|
artikel
|
| 103 |
First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo
|
Dernovšek, Jaka
|
|
|
153 |
C |
p.
|
artikel
|
| 104 |
FL118: A potential bladder cancer therapeutic compound targeting H2A.X identified through library screening
|
Fan, Guangrui
|
|
|
153 |
C |
p.
|
artikel
|
| 105 |
Flexible 2,4-diaminopyrimidine bearing a butyrolactone as Plasmodium falciparum dihydrofolate reductase inhibitors
|
Decharuangsilp, Sasithorn
|
|
|
153 |
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