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                             92 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A class of geranylquinol-derived polycyclic meroterpenoids from Arnebia euchroma against heart failure by reducing excessive autophagy and apoptosis in cardiomyocytes Zhao, Ling-Hao
151 C p.
 artikel
2 Acovenosigenin A β-glucoside mediates JAK2-STAT3 signaling pathway by targeting GP130 in A549 and H460 cells based on integrative analysis of transcriptome and proteome and biological verification Liu, Zhe
151 C p.
 artikel
3 Activity-based protein profiling in drug/pesticide discovery: Recent advances in target identification of antibacterial compounds Chen, Kunlun
151 C p.
 artikel
4 Advances in HER2-Targeted Therapies: From monoclonal antibodies to dual inhibitors developments in cancer treatment Bhagyalalitha, Meduri
151 C p.
 artikel
5 Alstomaphylines A–K, monoterpenoid bisindole alkaloids from Alstonia macrophylla with AChE inhibitory activity and cytotoxicity Li, Zi-Wei
151 C p.
 artikel
6 7-Amino-[1,2,4]triazolo[1,5-a][1,3,5]triazines as CK1δ inhibitors: Exploring substitutions at the 2 and 5-positions Grieco, Ilenia
151 C p.
 artikel
7 An innovative dual-organelle targeting NIR fluorescence probe for detecting hydroxyl radicals in biosystem and inflammation models Ma, Junyan
151 C p.
 artikel
8 A novel approach to investigate the combinatorial effects of TLK1 (Tousled-Like Kinase1) inhibitors with Temozolomide for glioblastoma therapy Priya, Bhanu
151 C p.
 artikel
9 Aromatase inhibitors for the treatment of breast cancer: An overview (2019–2023) Bhatia, Neha
151 C p.
 artikel
10 Auto-induction, biochemical characterization and application of a novel thermo-alkaline and detergent-stable lipase (S9 peptidase domain) from Thermotoga petrophila as cleaning additive and degrading oil/fat wastes Akram, Fatima
151 C p.
 artikel
11 Bio-inspired multifunctional and reusable LiP@MFO-GO and LiP@MFO-Chit hybrid enzyme complexes for efficient degradation of melanin Rathour, Ranju Kumari
151 C p.
 artikel
12 Cedrol in ginger (Zingiber officinale) as a promising hair growth drug: The effects of oral and external administration on hair regeneration and its mechanism Li, Tao
151 C p.
 artikel
13 Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities Tammam, Mohamed A.
151 C p.
 artikel
14 Chitosan decorated magnetic nanobiocatalyst of Bacillus derived α-amylase as a role model for starchy wastewater treatment, detergent additive and textile desizer Gupta, Nisha
151 C p.
 artikel
15 Comparative study of [18F]AlF-PAI-PDL1p and [68Ga]Ga-PAI-PDL1p as novel PD-L1 targeting PET probes for tumor imaging Bai, Lu
151 C p.
 artikel
16 Corrigendum to “Design, synthesis and biological evaluation of glucose metabolism inhibitors as anticancer agents” [Bioorg. Chem. 151 (2024) 107665] Cheng, Yao
151 C p.
 artikel
17 Critical review on plant-derived quorum sensing signaling inhibitors in pseudomonas aeruginosa Vadakkan, Kayeen
151 C p.
 artikel
18 Design and bio-evaluation of novel millepachine derivatives targeting tubulin colchicine binding site for treatment of osteosarcoma Geng, Dawei
151 C p.
 artikel
19 Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma Bouzian, Younos
151 C p.
 artikel
20 Design and structure-activity relationships of ether-linked alkylides: Hybrids of 3-O-descladinosyl macrolides and quinolone motifs Zhang, Na
151 C p.
 artikel
21 Design and synthesis of 6,20-epoxy A-ring modified oridonin derivatives with antitumor activity through extrinsic and mitochondrial pathways Li, Haonan
151 C p.
 artikel
22 Design of Multi-Target drugs of HDACs and other Anti-Alzheimer related Targets: Current strategies and future prospects in Alzheimer’s diseases therapy Soltan, Osama M.
151 C p.
 artikel
23 Design, synthesis and anticancer activity of β-carboline based pseudo-natural products by inhibiting AKT/mTOR signaling pathway Lv, Lijie
151 C p.
 artikel
24 Design, synthesis and antitumor activities of phthalazinone derivatives as PARP-1 inhibitors and PARP-1/HDAC-1 inhibitors Wu, Jie
151 C p.
 artikel
25 Design, synthesis and bioevaluation of dual EGFR-PI3Kα inhibitors for potential treatment of NSCLC Wang, Tingliang
151 C p.
 artikel
26 Design, synthesis, and biological activities of arecoline derivatives containing 1,3,4-oxadiazole structure Li, Taiqing
151 C p.
 artikel
27 Design, synthesis, and biological evaluation of β-carboline-cinnamic acid derivatives as DYRK1A inhibitors in the treatment of diabetes Guan, Li
151 C p.
 artikel
28 Design, synthesis and biological evaluation of glucose metabolism inhibitors as anticancer agents Cheng, Yao
151 C p.
 artikel
29 Design, synthesis and biological evaluation of novel quinazoline-derived EGFR/HER-2 dual-target inhibitors bearing a heterocyclic-containing tail as potential anti-tumor agents Hao, Shuang
151 C p.
 artikel
30 Design, synthesis, and biological evaluation of Pyrido[1,2-a]pyrimidin-4-one derivatives as novel allosteric SHP2 inhibitors Zhang, Le
151 C p.
 artikel
31 Design, synthesis, and in vivo and in vitro biological screening of pseudolaric acid B derivatives as potential anti-tumor agents Xu, Qian
151 C p.
 artikel
32 Development and biological evaluation of 68Ga-labeled peptides for potential application in HER2-positive colorectal cancer Zhang, Jinglin
151 C p.
 artikel
33 Development of a fluorescent ligand that specifically binds to the c-MYC G-quadruplex by migrating the benzene group on a carbazole-benzothiazolium scaffold Wang, Rui
151 C p.
 artikel
34 Development of new chiral 1,2,4-triazole-3-thiones and 1,3,4-thiadiazoles with promising in vivo anticonvulsant activity targeting GABAergic system and voltage-gated sodium channels (VGSCs) Karaküçük-İyidoğan, Ayşegül
151 C p.
 artikel
35 Development of non-acidic 4-methylbenzenesulfonate-based aldose reductase inhibitors; Design, Synthesis, Biological evaluation and in-silico studies Said, Gehad E.
151 C p.
 artikel
36 Directing novel ChoKα1 inhibitors using MamC-mediated biomimetic magnetic nanoparticles: a way to improve specificity and efficiency Sola-Leyva, Alberto
151 C p.
 artikel
37 Discovery and development of thiazolidine-2,4-dione derivatives as Bcl-2/Mcl-1 dual inhibitors Long, Jiabing
151 C p.
 artikel
38 Discovery and evolution of berberine analogues as anti-Helicobacter pylori agents with multi-target mechanisms Zhang, Xin
151 C p.
 artikel
39 Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors Sabt, Ahmed
151 C p.
 artikel
40 Discovery of novel amide derivatives against VEGFR-2/tubulin with potent antitumor and antiangiogenic activity Liu, Zhenling
151 C p.
 artikel
41 Discovery of novel pyrazolo[1,5-a]pyrimidine derivatives as selective ROCK2 inhibitors with anti-breast cancer migration and invasion activities Cao, Zhi
151 C p.
 artikel
42 Discovery of pyrimidine-2,4-diamine analogues as efficiency anticancer drug by targeting GTSE1 Xing, Sunhui
151 C p.
 artikel
43 Editorial Board
151 C p.
 artikel
44 Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents Naguib, Bassem H.
151 C p.
 artikel
45 Haperforatones A-M, thirteen undescribed limonoids from Harrisonia perforata with anti-inflammatory activity Wang, Qing
151 C p.
 artikel
46 Heteryunine A, an amidated tryptophan-catechin-spiroketal hybrid with antifibrotic activity from Heterosmilax yunnanensis Du, Rong-Rong
151 C p.
 artikel
47 Identification of antimycobacterial 8-hydroxyquinoline derivatives as in vitro enzymatic inhibitors of Mycobacterium tuberculosis enoyl-acyl carrier protein reductase Joaquim, Angélica Rocha
151 C p.
 artikel
48 Identification of diterpenoids from Salvia castanea Diels f. tomentosa Stib and their antitumor activities Wang, Dong-Dong
151 C p.
 artikel
49 Intersite communication in dimeric enzymes highlighted by structural and thermodynamic analysis of didansyltyrosine binding to thymidylate synthases Venturelli, Alberto
151 C p.
 artikel
50 Intriguing steroid glycosides for cancer therapy by suppressing the DNA damage response and mTOR/S6K signaling pathways An, Pei-Pei
151 C p.
 artikel
51 Investigating the effect of ligand structure on the anticancer properties of several new Co(II) complexes of vitaminB3-based phosphoramides Oroujzadeh, Nasrin
151 C p.
 artikel
52 Investigation of relationships between metabolic chemical reporter structures and S-glyco-modification effects Dou, Biao
151 C p.
 artikel
53 Issue TOC
151 C p.
 artikel
54 Macrocyclic peptides derived from AcPHF6* and AcPHF6 to selectively modulate the Tau aggregation Dangi, Abha
151 C p.
 artikel
55 Metal-free internal nucleophile-triggered domino route for synthesis of fused quinoxaline [1,4]-diazepine hybrids and the evaluation of their DNA binding properties Majhi, Bhim
151 C p.
 artikel
56 Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide Liu, Peng
151 C p.
 artikel
57 Multi-component forms of the 2nd generation H1 receptor antagonist drug, Bilastine and its enhanced physicochemical characteristics Kar, Ananya
151 C p.
 artikel
58 N-Acyl phenothiazines as mycobacterial ATP synthase inhibitors: Rational design, synthesis and in vitro evaluation against drug sensitive, RR and MDR-TB Reddyrajula, Rajkumar
151 C p.
 artikel
59 New cyclometalated iridium(III) complexes bearing substituted 2-(1H-benzimidazol-2-yl)quinoline: Synthesis, characterization, electrochemical and anticancer studies Sahin, Cigdem
151 C p.
 artikel
60 New polycyclic polyprenylated acylphloroglucinols with antidepressant activities from Hypericum perforatum L. Pan, Xue-Ge
151 C p.
 artikel
61 New sesquiterpenes and viridin derivatives from Penicillium sp. Ameliorates NAFLD by regulating the PINK1/Parkin mitophagy pathway Zhang, Hang
151 C p.
 artikel
62 New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer Espinosa-Bustos, Christian
151 C p.
 artikel
63 Novel antibody-drug conjugates based on DXd-ADC technology Chen, Rong
151 C p.
 artikel
64 Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations Elkotamy, Mahmoud S.
151 C p.
 artikel
65 Novel mandelic acid derivatives containing piperazinyls as potential candidate fungicides against Monilinia fructicola: Design, synthesis and mechanism study Zheng, Ya
151 C p.
 artikel
66 Novel PROTAC probes targeting FOSL1 degradation to eliminate head and neck squamous cell carcinoma cancer stem cells Zaman, Shadid U.
151 C p.
 artikel
67 Oleanane-type triterpenoids from Sabia limoniacea and their anti-inflammatory activities Huang, Yan
151 C p.
 artikel
68 Pyrimidine-based sulfonamides and acetamides as potent antimicrobial Agents: Synthesis, Computational Studies, and biological assessment Indalkar, Supriya
151 C p.
 artikel
69 Rational design on loop regions for precisely regulating flexibility of catalytic center to mitigate overoxidation of prazole sulfides by Baeyer-Villiger monooxygenase Su, Bingmei
151 C p.
 artikel
70 Rosmarinic acid turned α-syn oligomers into non-toxic species preserving microtubules in Raw 264.7 cells Flores, Nicolás
151 C p.
 artikel
71 Saponins from Dolichos lablab seeds with anti-inflammatory activity Zhang, Wei
151 C p.
 artikel
72 Scutellarein derivatives with histamine H3 receptor antagonism and cholinesterase inhibitory potency as multi target-directed ligands for possible Alzheimer’s disease therapy Chen, Jiao
151 C p.
 artikel
73 13,14-seco withaphysalins from Physalis minima and their inhibitory effects on NLRP3 inflammasome activation Hu, Bintao
151 C p.
 artikel
74 Sesquiterpenoids from Carpesium abrotanoides and their anti-inflammatory activity both in vitro and in vivo Zhang, Xiao-Fang
151 C p.
 artikel
75 Synthesis and antimicrobial activity testing of quaternary ammonium silane compounds Kuruca, Tuğçe
151 C p.
 artikel
76 Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents Chen, Ling
151 C p.
 artikel
77 Synthesis and broad-spectrum biocidal effect of novel gemini quaternary ammonium compounds Zivna, Natalie
151 C p.
 artikel
78 Synthesis and evaluation of 5,15-diaryltetrabenzoporphyrins as photosensitizers for photo-diagnosis and photodynamic activity of tumors Mi, Le
151 C p.
 artikel
79 Synthesis, biological evaluation, and molecular docking studies of novel N-substituted piperazine-tethered thiophene-3-carboxamide selenides as potent antiproliferative agents with EGFR kinase inhibitory activity Makhal, Priyanka N.
151 C p.
 artikel
80 Synthetic routes and clinical application of Small-Molecule HER2 inhibitors for cancer therapy Liu, He-Nan
151 C p.
 artikel
81 Targeting DNA methyltransferases for cancer therapy Wang, Kaiyue
151 C p.
 artikel
82 Targeting histone methylation and demethylation for non-alcoholic fatty liver disease Du, Yuanbing
151 C p.
 artikel
83 Targeting next-generation PDE4 inhibitors in search of potential management of rheumatoid arthritis and psoriasis Bhuktar, Harshavardhan
151 C p.
 artikel
84 Tetrahydropyridine appended 8-aminoquinoline derivatives: Design, synthesis, in silico, and in vitro antimalarial studies Sharma, Ganesh
151 C p.
 artikel
85 The potential of marine natural Products: Recent Advances in the discovery of Anti-Tuberculosis agents Peng, Xinyu
151 C p.
 artikel
86 The utility of Streptococcus mutans undecaprenol kinase for the chemoenzymatic synthesis of diverse non-natural isoprenoids Kumar, Vikas
151 C p.
 artikel
87 Transcriptomic analysis of MCF7 breast cancer cells treated with MGBs reveals a profound inhibition of estrogen receptor genes Alniss, Hasan Y.
151 C p.
 artikel
88 TRIP13 − a potential drug target in cancer pharmacotherapy Jacob Bunu, Samuel
151 C p.
 artikel
89 Unlocking the potential of higher-molecular-weight 5-HT7R ligands: Synthesis, affinity, and ADMET examination Pyka, Patryk
151 C p.
 artikel
90 Unveiling anti-diabetic potential of new thiazole-sulfonamide derivatives: Design, synthesis, in vitro bio-evaluation targeting DPP-4, α-glucosidase, and α-amylase with in-silico ADMET and docking simulation Khamees Thabet, Hamdy
151 C p.
 artikel
91 Unveiling the potential of isatin-grafted phenyl-1,2,3-triazole derivatives as dual VEGFR-2/STAT-3 inhibitors: Design, synthesis and biological assessments Elsebaie, Heba A.
151 C p.
 artikel
92 Visualization of nonsmall-cell lung cancer by near-infrared fluorescence imaging with tumor-targeting peptide ABT-510 Tu, Yuanbiao
151 C p.
 artikel
                             92 gevonden resultaten
 
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