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                             71 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A comprehensive review of multi-target directed ligands in the treatment of Alzheimer’s disease Pathak, Chandni

144 C p.
artikel
2 A GSH-resistant FK228 analogue containing a stable disulfide bond Zhan, Mei-miao

144 C p.
artikel
3 Alpha-glucosidase inhibitory and hypoglycemic effects of imidazole-bearing thioquinoline derivatives with different substituents: In silico, in vitro, and in vivo evaluations Azmi, Anita

144 C p.
artikel
4 Anti-necroptosis and anti-ferroptosis compounds from the Deep-Sea-Derived fungus Aspergillus sp. MCCC 3A00392 Yu, Hao-Yu

144 C p.
artikel
5 Artificial structural proteins: Synthesis, assembly and material applications Li, Ming

144 C p.
artikel
6 Assessment of Mononuclear/Dinuclear copper acylhydrazone complexes for lung cancer treatment Wu, Youru

144 C p.
artikel
7 Atrachinenins D–S, novel meroterpenoids with geranyl hydroquinone moiety from Atractylodes chinensis by the LC/MS-based molecular decoy and targeted isolation Chen, Fei-Long

144 C p.
artikel
8 Bioassay-guided isolation of anti-leukemic steroids from Aglaia abbreviata by inducing apoptosis Liu, Keying

144 C p.
artikel
9 Biochemical evaluation and ligand binding studies on glycerophosphodiester phosphodiesterase from Staphylococcus aureus using STD-NMR spectroscopy and molecular docking analysis Salar, Uzma

144 C p.
artikel
10 Chemosensitization of non-small cell lung cancer to sorafenib via non-hydroxamate s-triazinedione-based MMP-9/10 inhibitors Khalil, Hosam H.

144 C p.
artikel
11 Comparative investigation into the anticancer activity of analogs of marine coelenterazine and coelenteramine Magalhães, Carla M.

144 C p.
artikel
12 Constructing triazole-modified quinazoline derivatives as selective c-MYC G-quadruplex ligands and potent anticancer agents through click chemistry Cai, Jiong-Heng

144 C p.
artikel
13 Corydecusines A-H, new phthalideisoquinoline hemicetal alkaloids from the bulbs of Corydalis decumbens inhibit Tau pathology by activating autophagy mediated by AMPK-ULK1 pathway Li, Sheng

144 C p.
artikel
14 Decoding active compounds and molecular targets of herbal medicine by high-throughput metabolomics technology: A systematic review Wang, Zhibo

144 C p.
artikel
15 Design and synthesis of novel dithiazole carboxylic acid Derivatives: In vivo and in silico investigation of their Anti-Inflammatory and analgesic effects Yücel, Nazlı Turan

144 C p.
artikel
16 Design and synthesis of quinazolin-4-one derivatives as potential anticancer agents and investigation of their interaction with RecQ helicases Haggag, Hanan S.

144 C p.
artikel
17 Design, synthesis and anticholinergic properties of novel α-benzyl dopamine, tyramine, and phenethylamine derivatives Naderi, Ali

144 C p.
artikel
18 Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders Li, Xiaomei

144 C p.
artikel
19 Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity Abdelhakeem, Marwa M.

144 C p.
artikel
20 Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers Abdulrahman, Fatma G.

144 C p.
artikel
21 Design, synthesis, and pharmacological evaluation of novel benzothiazole derivatives targeting LCK in acute lymphoblastic leukemia Chen, Yanmei

144 C p.
artikel
22 Dibenzofurans from nature: Biosynthesis, structural diversity, sources, and bioactivities Liang, Xin

144 C p.
artikel
23 Discovery of adamantane-type polycyclic polyprenylated acylphloroglucinols that can prevent concanavalin A-induced autoimmune hepatitis in mice Tao, Bo

144 C p.
artikel
24 Discovery of a quinoline-containing compound JT21-25 as a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1) Pang, Lidan

144 C p.
artikel
25 Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma Blua, Federica

144 C p.
artikel
26 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties Zhuo, Ning

144 C p.
artikel
27 Discovery of 2,4-diarylaminopyrimidine derivatives bearing sulfonamide moiety as novel FAK inhibitors Li, Ridong

144 C p.
artikel
28 Discovery of novel selective phosphodiesterase‑1 inhibitors for the treatment of acute myelogenous leukemia Le, Mei-Ling

144 C p.
artikel
29 Druggable targets of protein tyrosine phosphatase Family, viz. PTP1B, SHP2, Cdc25, and LMW-PTP: Current scenario on medicinal Attributes, and SAR insights Bhavana,

144 C p.
artikel
30 Editorial Board
144 C p.
artikel
31 Exploration of oxadiazole clubbed benzhydrylpiperazine pharmacophoric features as structural feature for antidepressant activity: In vitro, in vivo and in silico analysis Kumar Nandi, Nilay

144 C p.
artikel
32 Four undescribed coumarin derivatives, with ten amides from the roots of Ficus hirta and their cytotoxic activities Ye, Xian-Sheng

144 C p.
artikel
33 Glaucatotones A−I: Guaiane-type sesquiterpenoids from the roots of Lindera glauca with anti-inflammatory activity Pan, Xinyuan

144 C p.
artikel
34 HUH Endonuclease: A Sequence-specific Fusion Protein Tag for Precise DNA-Protein Conjugation Du, Jiajun

144 C p.
artikel
35 Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA) Khaleel, Eman F.

144 C p.
artikel
36 Identification of new multi-substituted 1H-pyrazolo[3,4-c]pyridin-7(6H)-ones as soluble guanylyl cyclase (sGC) stimulators with vasoprotective and anti-inflammatory activities Kintos, Dionysios-Panagiotis

144 C p.
artikel
37 Identification of novel Nrf2-activating neuroprotective agents: Elucidation of structural congeners of (-)-galiellalactone and congener-based novel Nrf2 activators Kim, Taewoo

144 C p.
artikel
38 Identification of thienopyrimidine derivatives tethered with sulfonamide and other moieties as carbonic anhydrase inhibitors: Design, synthesis and anti-proliferative activity Higazy, Samah

144 C p.
artikel
39 Inhibition of staphylococcal nuclease by benzimidazole-based Ligand: Implications in DNA-Mediated entrapment and uptake of MRSA by Macrophage-like cells Konwar, Barlina

144 C p.
artikel
40 In vitro safety signals for potential clinical development of the anti-inflammatory pregnane X receptor agonist FKK6 Dvořák, Zdeněk

144 C p.
artikel
41 Isolation and target identification of anti-renal fibrosis compounds from Cordyceps militaris Yang, Wei

144 C p.
artikel
42 Issue TOC
144 C p.
artikel
43 Multiple medicinal chemistry strategies of targeting KRAS: State-of-the art and future directions Shang, Yanguo

144 C p.
artikel
44 Multi-targeting oligopyridiniums: Rational design for biofilm dispersion and bacterial persister eradication Li, Jiaqi

144 C p.
artikel
45 New pyranopyrazole based derivatives: Design, synthesis, and biological evaluation as potential topoisomerase II inhibitors, apoptotic inducers, and antiproliferative agents Sobh, Eman A.

144 C p.
artikel
46 Novel 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide based thiosemicarbazides as potent and selective inhibitors of tumor-associated human carbonic anhydrase IX and XII: Synthesis, cytotoxicity, and molecular modelling studies Demir-Yazıcı, Kübra

144 C p.
artikel
47 Optimization and biological evaluation of l-DOPA derivatives as potent influenza PAN endonuclease inhibitors with multi-site binding characteristics Ruan, Jiaai

144 C p.
artikel
48 Photoactive rhodamine-based photosensitizer eliminates Staphylococcus aureus via superoxide radical photosensitization Zhang, Zhishang

144 C p.
artikel
49 Potential oral VEGFR2 inhibitors: Treatment of wet age-related macular degeneration Xiu, Xiaomeng

144 C p.
artikel
50 Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers Ma, Ting

144 C p.
artikel
51 Properties and synergistic effects of a nonionic backbone and aminoalkyl modified nucleosides in RNAs Sawada, Hibiki

144 C p.
artikel
52 Rational design and synthesis of triazene-amonafide derivatives as novel potential antitumor agents causing oxidative damage towards DNA through intercalation mode Sun, Ping

144 C p.
artikel
53 Recent advances in biocatalytic C–N bond-forming reactions Yin, Hong-Ning

144 C p.
artikel
54 Recent advances in hypoxia-activated compounds for cancer diagnosis and treatment Yuan, Xiaoyu

144 C p.
artikel
55 Recent advances in pyruvate dehydrogenase kinase inhibitors: Structures, inhibitory mechanisms and biological activities Li, Yiyang

144 C p.
artikel
56 Recent advances of Pin1 inhibitors as potential anticancer agents Bai, Yiru

144 C p.
artikel
57 Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform Nao, Sang-Cuo

144 C p.
artikel
58 Second generation of pyrimidin-quinolone hybrids obtained from virtual screening acting as sphingosine kinase 1 inhibitors and potential anticancer agents Vettorazzi, Marcela

144 C p.
artikel
59 Self-feedback loop-containing synthetic mRNA switches for controlled microRNA sensing Liang, Zhenghua

144 C p.
artikel
60 Self-lysis microbial consortia for predictable multi-proteins assembly Zhang, Xi

144 C p.
artikel
61 Shaping the future of antiviral Treatment: Spotlight on Nucleobase-Containing drugs and their revolutionary impact Wong, Xi Khai

144 C p.
artikel
62 Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene Hong, Wenbin

144 C p.
artikel
63 Study of novel ginsenoside metabolites targeting HSP70 as anti-prostate cancer drugs Xu, Lei

144 C p.
artikel
64 Synthesis and biological evaluation of new nicotinic acid derivatives as potential anti-inflammatory agents with enhanced gastric safety profile Ahmed, Eman M.

144 C p.
artikel
65 Synthesis and mechanistic study of ultrashort peptides that inhibits Alzheimer’s Aβ-aggregation-induced neurotoxicity Sehra, Naina

144 C p.
artikel
66 Synthesis, antitumor activity evaluation of 2-selenocyano-3-selenocyanoalkyloxyestradiols with a bisselenocyanate structure Huang, Yanmin

144 C p.
artikel
67 Synthesis, biochemical and computational evaluations of novel bis-acylhydrazones of 2,2′-(1,1′-biphenyl)-4,4′-diylbis(oxy))di(acetohydrazide) as dual cholinesterase inhibitors Ibrahim, Muhammad

144 C p.
artikel
68 Synthesis, structure, theoretical calculation and antibacterial property of two novel Zn(II)/Ni(II) compounds based on 3, 5-dichlorosalicylaldehyde thiocarbamide ligand Wang, Yuan-Peng

144 C p.
artikel
69 The progress of small molecules against cannabinoid 2 receptor (CB2R) Zhang, Qinying

144 C p.
artikel
70 Thiazolidine-2,4-dione derivatives as potential α-glucosidase inhibitors: Synthesis, inhibitory activity, binding interaction and hypoglycemic activity Li, Mengyue

144 C p.
artikel
71 Ursonic acid attenuates spermatogenesis in oligozoospermia mice through inhibiting ferroptosis Dong, Jin

144 C p.
artikel
                             71 gevonden resultaten
 
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