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                             121 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Acid-triggered controlled release and fluorescence-switchable phthalocyanine nanoassemblies combined with O2-economizer for tumor imaging and collaborative photodynamic antitumor therapy Liu, Xinxin
143 C p.
 artikel
2 A comprehensive review of small molecules targeting PI3K pathway: Exploring the structural development for the treatment of breast cancer Dubey, Rahul
143 C p.
 artikel
3 Advances in synthesis and biological evaluation of CDK2 inhibitors for cancer therapy Patel, Dharmesh A.
143 C p.
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4 A highly oxidized germacranolide from elephantopus tomentosus inhibits the growth of hepatocellular carcinoma cells by targeting EGFR in vitro and in vivo Li, Qian
143 C p.
 artikel
5 A near-infrared aggregation-induced emission photosensitizer targeting mitochondria for depleting Cu2+ to trigger light-activated cancer cells oncosis Xue, Ke
143 C p.
 artikel
6 A newly synthesized magnetic nanoparticle coated with glycidyl methacrylate monomer and 1,2,4-Triazole: Immobilization of α-Amylase from Bacillus licheniformis for more reuse, stability, and activity in the presence of H2O2 Kaptan Usul, Sedef
143 C p.
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7 Apigenin analogs as α-glucosidase inhibitors with antidiabetic activity Liu, Honghui
143 C p.
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8 A supercritical fluid co-extract of turmeric powder and dried coconut shreds shows neuroprotection against AlCl3-induced Alzheimer’s disease in rats through nose to brain delivery Sharma, Abhinav
143 C p.
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9 A turn-on fluorescent probe for detecting and bioimaging of HOCl in inflammatory and liver disease models Zhang, Peng
143 C p.
 artikel
10 Bialorastins A–F, highly oxygenated and polycyclic andrastin-type meroterpenoids with proangiogenic activity from the deep-sea cold-seep-derived fungus Penicillium bialowiezense CS-283 Yan, Li-Hong
143 C p.
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11 Biological activity and structural modification of isosteviol over the past 15 years Yang, Youfu
143 C p.
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12 Bioseparation of rare earth elements and high value-added biomaterials applications Qian, Xining
143 C p.
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13 Boron-containing carbonic anhydrases inhibitors Giovannuzzi, Simone
143 C p.
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14 5′-cap RNA/SAM mimetic conjugates as bisubstrate inhibitors of viral RNA cap 2′-O-methyltransferases Ahmed-Belkacem, Rostom
143 C p.
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15 Carbazole-based mitochondria-targeted fluorescent probes for in vivo viscosity and cyanide detection in cells and zebrafish Han, Lin-Lin
143 C p.
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16 Catalyzing a Cure: Discovery and development of LRRK2 inhibitors for the treatment of Parkinson’s disease Baidya, Anurag TK
143 C p.
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17 Challenging the anticolorectal cancer capacity of quinoxaline-based scaffold via triazole ligation unveiled new efficient dual VEGFR-2/MAO-B inhibitors Ayoup, Mohammed Salah
143 C p.
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18 Characteristic alkaloids from Stemona sessilifolia with lung protective effects Jiang, Wanru
143 C p.
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19 Characterization of the metabolites of Eucommiae Cortex in rats provides a further insight into its estrogen-like effective substances Ding, Liqin
143 C p.
 artikel
20 Chemical synthesis of a 28 kDa full-length PET degrading enzyme ICCG by the removable backbone modification strategy Gao, Yun-Pu
143 C p.
 artikel
21 Click chemistry in the synthesis of antibody-drug conjugates Dudchak, Rostyslav
143 C p.
 artikel
22 Computational Design, Synthesis, and Bioevaluation of 2-(Pyrimidin-4-yl)oxazole-4-carboxamide Derivatives: Dual Inhibition of EGFRWT and EGFRT790M with ADMET Profiling Raghunath Khedkar, Nilesh
143 C p.
 artikel
23 Corrigendum to “Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators” [Bioorg. Chem. 117 (2021) 105427] Lotfy, Gehad
143 C p.
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24 Corrigendum to “Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma” [Bioorg. Chem. 129 (2022) 106124] Barakat, Assem
143 C p.
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25 Corrigendum to “The active phthalate metabolite, DHEP, induces proliferation and metastasis of prostate cancer cells via upregulation of β-catenin and downregulation of KLF7” [Bioorganic Chem., 141 (2023) 106864] Li, Hecheng
143 C p.
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26 C3-Spirooxindoles: Divergent chemical synthesis and bioactivities (2018–2023) Helal, Mohamed H.
143 C p.
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27 Decaging-to-labeling: Development and investigation of quinone methide warhead for protein labeling Guo, Fuhu
143 C p.
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28 Deciphering single-cell protein secretion and gene expressions by constructing cell-antibody conjugates Li, Yachao
143 C p.
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29 Design and synthesis of luotonin A-derived topoisomerase targeting scaffold with potent antitumor effect and low genotoxicity Li, Xin-Wei
143 C p.
 artikel
30 Design of balanced dual-target inhibitors of EGFR and microtubule Liu, Yifan
143 C p.
 artikel
31 Design, synthesis, and biological evaluation of novel capsaicin-tacrine hybrids as multi-target agents for the treatment of Alzheimer's disease Long, Juanyue
143 C p.
 artikel
32 Design, synthesis, and biological evaluation of novel donepezil-tacrine hybrids as multi-functional agents with low neurotoxicity against Alzheimer’s disease Wang, Ningwei
143 C p.
 artikel
33 Design, synthesis, and biological evaluation of novel tryptanthrin derivatives as selective acetylcholinesterase inhibitors for the treatment of Alzheimer's disease Xia, Jucheng
143 C p.
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34 Design, synthesis, and biological evaluation of N-(pyridin-3-yl)pyrimidin-4-amine analogues as novel cyclin-dependent kinase 2 inhibitors for cancer therapy Zeng, Wen-Bin
143 C p.
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35 Design, synthesis and biological evaluation of potent epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors against resistance mutation for lung cancer treatment Wang, Cheng
143 C p.
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36 Design, synthesis, and evaluation of pirfenidone-NSAIDs conjugates for the treatment of idiopathic pulmonary fibrosis Lu, Xiang
143 C p.
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37 Design, synthesis and evaluation of quinazoline derivatives as Gαq/11 proteins inhibitors against uveal melanoma Fan, Guangjin
143 C p.
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38 Design, synthesis, and evaluation of VHL-based EZH2 degraders for breast cancer Xiao, Boren
143 C p.
 artikel
39 Design, synthesis, molecular docking and biological evaluation of 1,3,5-trisubstituted-1H-pyrazole derivatives as anticancer agents with cell cycle arrest, ERK and RIPK3- kinase activities Boshta, Nader M.
143 C p.
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40 Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease Bajad, Nilesh Gajanan
143 C p.
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41 Development of new thieno[2,3-d]pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activities Elsebaie, Heba A.
143 C p.
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42 Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides K. A. Abdelall, Eman
143 C p.
 artikel
43 Discovery and characterization of natural product luteolin as an effective inhibitor of human pyridoxal kinase Zhu, Yunmei
143 C p.
 artikel
44 Discovery of a near-infrared fluorescent probe for G-quadruplexes by exploiting the concept of unfolding-intramolecular-aggregation-induced emission Wang, Xiao-Dong
143 C p.
 artikel
45 Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor Sun, Yaoliang
143 C p.
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46 Discovery of highly efficient CRBN-recruiting HPK1-PROTAC as a potential chemical tool for investigation of scaffolding roles in TCR signaling Zeng, Shenxin
143 C p.
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47 Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups Huang, Qiao
143 C p.
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48 Discovery of LH10, a novel fexaramine-based FXR agonist for the treatment of liver disease Huang, Wanqiu
143 C p.
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49 Discovery of novel 1H-benzo[d]imidazole-4,7-dione based transglutaminase 2 inhibitors as p53 stabilizing anticancer agents in renal cell carcinoma Kim, Ga-Ram
143 C p.
 artikel
50 Divergent synthesis of fractionated Cannabis sativa extract led to multiple cannabinoids C-&O-glycosides with anti-proliferative/anti-metastatic properties Nalli, Yedukondalu
143 C p.
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51 Dual chemodynamic/photothermal therapeutic nanoplatform based on DNA-functionalized prussian blue Zeng, Qin
143 C p.
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52 Editorial Board
143 C p.
 artikel
53 Enhancement efficiency delivery of antiviral Molnupiravir-drug via the loading with self-assembly nanoparticles of pycnogenol and cellulose which are decorated by zinc oxide nanoparticles for COVID-19 therapy El-Shafai, Nagi M.
143 C p.
 artikel
54 Enhancing nicotinamide N-methyltransferase bisubstrate inhibitor activity through 7-deazaadenosine and linker modifications Li, Pengyu
143 C p.
 artikel
55 Evaluation of a biomarker (NO) dynamics in inflammatory zebrafish and periodontitis saliva samples via a fast-response and sensitive fluorescent probe Zhang, Yibin
143 C p.
 artikel
56 Evaluation of antihypertensive activity and molecular docking analysis of Padina boergesenii extract Patel, Nidhi
143 C p.
 artikel
57 Exploration of costunolide derivatives as potential anti-inflammatory agents for topical treatment of atopic dermatitis by inhibiting MAPK/NF-κB pathways Lu, Cheng
143 C p.
 artikel
58 Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors Tamhaev, Rasoul
143 C p.
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59 Expression of a thermostable glucose-stimulated β-glucosidase from a hot-spring metagenome and its promising application to produce gardenia blue Mo, Haiying
143 C p.
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60 Fluorinated azoles as effective weapons in fight against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies Zhao, Xuanming
143 C p.
 artikel
61 Fourteen new 2-benzylbenzofuran glycosides with cardioprotective activity from Heterosmilax yunnanensis Du, Rong-Rong
143 C p.
 artikel
62 Fructooligosaccharides from Cynoglossum tubiflorus: Effect of the molecular size on their antidiabetic activity in high-fat diet and alloxan induced diabetic rats Dallali, Dhouha
143 C p.
 artikel
63 Green approach to the synthesis of α-aminophosphonate-tetrahydroisoquinoline hybrids and their anti-cholinesterase activity Marchán-García, Joaquín
143 C p.
 artikel
64 Groebke Blackburn Bienaymé-mediated multi-component synthesis of selective HDAC6 inhibitors with anti-inflammatory properties Kraft, Fabian B.
143 C p.
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65 Human serum albumin as a potential drug delivery system for N-methylated hot spot insulin analogs inhibiting hormone aggregation Wasko, Joanna
143 C p.
 artikel
66 Identification and evolution of non-traditional nitrilase from Spirosoma linguale DSM 74 with high hydration activity Sun, Yangyang
143 C p.
 artikel
67 Identification of diverse sesquiterpenoids with anti-fibrotic potential from Inula japonica Thunb. Peng, Yulin
143 C p.
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68 Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents Lin, Gang
143 C p.
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69 Identification of novel ureido benzothiophenes as dual VEGFR-2/EGFR anticancer agents Eldehna, Wagdy M.
143 C p.
 artikel
70 In situ interaction between the hormone 17α-ethynylestradiol and the liquid-ordered phase composed of the lipid rafts sphingomyelin and cholesterol Ruiz, Gilia Cristine Marques
143 C p.
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71 In vitro α-amylase and α-glucosidase inhibition study of dihydropyrimidinones synthesized via one-pot Biginelli reaction in the presence of a green catalyst Kamat, Vinuta
143 C p.
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72 Iodoquinazoline-derived VEGFR-2 and EGFRT790M dual inhibitors: Design, synthesis, molecular docking and anticancer evaluations Mohamed, Abeer A.
143 C p.
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73 Issue TOC
143 C p.
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74 Molecular glues targeting GSPT1 in cancers: A potent therapy Zhang, Dandan
143 C p.
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75 Molecular hybrids of substituted phenylcarbamoylpiperidine and 1,2,4-triazole methylacetamide as potent 15-LOX inhibitors: Design, synthesis, DFT calculations and molecular docking studies Nawaz, Zahid
143 C p.
 artikel
76 Near-infrared light controlled protein degradation by photo-caged lenalidomide and pomalidomide Zhu, Yaoji
143 C p.
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77 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation Zheng, Yingying
143 C p.
 artikel
78 New fusidane-type nortriterpenoids from the Arctic marine-derived fungus Simplicillium lamellicola culture medium with their inhibitory effect on benign prostatic hyperplasia Kwon, Haeun
143 C p.
 artikel
79 New resveratrol analogs as improved biologically active structures: Design, synthesis and computational modeling Mlakić, Milena
143 C p.
 artikel
80 New thiophene-1,3,4-oxadiazole-thiazolidine-2,4-dione hybrids: Synthesis, MCF-7 inhibition and binding studies Doddagaddavalli, Manasa A.
143 C p.
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81 N-(3-Methoxyphenyl)-6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)pyridin-2-amine is an inhibitor of the FLT3-ITD and BCR-ABL pathways, and potently inhibits FLT3-ITD/D835Y and FLT3-ITD/F691L secondary mutants Wang, Xiuqi
143 C p.
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82 Novel GSH-responsive prodrugs derived from indole-chalcone and camptothecin trigger apoptosis and autophagy in colon cancer Wang, Hui
143 C p.
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83 Novel heptafluoroisopropyl N-phenylpyrazole aryl amides containing cyanoalkyl groups: Design, synthesis, insecticidal activity, docking studies and theoretical calculations Liu, Dongdong
143 C p.
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84 Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study Eldehna, Wagdy M.
143 C p.
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85 Novel 1,3,4-oxadiazole hybrids of 3-n-butylphthalide derivatives as potential anti-ischemic stroke agents Yu, Qinyang
143 C p.
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86 Novel quinazolinone Derivatives: Design, synthesis and in vivo evaluation as potential agents targeting Alzheimer disease Moftah, Hadeer K.
143 C p.
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87 Novel sulfonyl-substituted tetrandrine derivatives for colon cancer treatment by inducing mitochondrial apoptosis and inhibiting PI3K/AKT/mTOR pathway Ling, Jie
143 C p.
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88 NQO-1 activatable NIR photosensitizer for visualization and selective killing of breast cancer cells Li, Zhipeng
143 C p.
 artikel
89 Old trees bloom new flowers, lysosome targeted near-infrared fluorescent probe for ratiometric sensing of hypobromous acid in vitro and in vivo based on Nile red skeleton Zhao, Wanqing
143 C p.
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90 Panaxadiol carbamate derivatives: Synthesis and biological evaluation as potential multifunctional anti-Alzheimer agents Quan, Yin-Sheng
143 C p.
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91 Pathology, target discovery, and the evolution of XO inhibitors from the first discovery to recent advances (2020–2023) Kumar, Nitish
143 C p.
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92 Penicimides A and B, two novel diels–alder [4 + 2] cycloaddition ergosteroids from Penicillium herquei Deng, Mengyi
143 C p.
 artikel
93 Platanosides from Platanus × acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis Wu, Xi-Ying
143 C p.
 artikel
94 Potential therapeutic medicines for renal fibrosis: Small-molecule compounds and natural products Xiang, Yu
143 C p.
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95 Programming and monitoring surface-confined DNA computing Sun, Chenyun
143 C p.
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96 Recent advances in the synthesis and antimalarial activity of 1,2,4-trioxanes Rathi, Komal
143 C p.
 artikel
97 Recent advances of vacuolar protein-sorting 34 inhibitors targeting autophagy Chen, Long
143 C p.
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98 Recent developments of P-glycoprotein inhibitors and its structure–activity relationship (SAR) studies Zhao, Xuanming
143 C p.
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99 Revealing protein trafficking by proximity labeling-based proteomics Wang, Yankun
143 C p.
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100 RNA-binding MSI proteins and their related cancers: A medicinal chemistry perspective Liu, Chenxin
143 C p.
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101 Selective inhibition of SIRT2: A disputable therapeutic approach in cancer therapy Kaya, Selen Gozde
143 C p.
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102 Structural diversity of microbial secondary metabolites based on chemical epigenetic manipulation Lv, Huawei
143 C p.
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103 Structurally diverse amides from Chloranthus henryi var. hupehensis and their anti-inflammatory activities by blocking Akt phosphorylation Zhang, Dan-Yang
143 C p.
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104 Structurally diverse stilbenes from Gnetum parvifolium and their anti-neuroinflammatory activities Yan, Qi-Wei
143 C p.
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105 Sucrosephenylpropanoid esters and isoflavonoids isolated from Belamcanda chinensis roots and their potential anti-osteoclastogenic activity Ha, Manh Tuan
143 C p.
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106 Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity against antibiotic-resistant bacteria Ye, Jiqing
143 C p.
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107 Synthesis and application of clinically approved small-molecule drugs targeting androgen receptor Gao, Hua
143 C p.
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108 Synthesis and biological evaluation of 2′-hydroxychalcone derivatives as AMPK activators Vu Nguyen, Duy
143 C p.
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109 Synthesis and biological evaluations of 8-biaryl-2,2-dimethylbenzopyranamide derivatives against Alzheimer's disease and ischemic stroke Cao, Ruolin
143 C p.
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110 Synthesis and characterization of bis-amide SSE1917 as a microtubule-stabilizing anticancer agent Iqbal, Sana
143 C p.
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111 Synthesis and photodynamic activity of novel thieno[3,2–b]thiophene fused BODIPYs with good bio-solubility and anti-aggregation effect Cao, Ning
143 C p.
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112 Synthesis, in vitro, and in silico studies of new derivatives of diphenylpiperazine scaffold: A key substructure for MAO inhibition El-Halaby, Lamiaa O.
143 C p.
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113 Synthesis, molecular docking and biological evaluation of 1,2,4-oxadiazole based novel non-steroidal derivatives against prostate cancer Kumar, Shubham
143 C p.
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114 Synthesis, molecular docking, electrochemical and fluorimetric analysis of new caffeic and cinnamic acid-conjugated hemorphin derivatives designed as potential anticonvulsant and antinociceptive agents Todorov, Petar
143 C p.
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115 Synthetic and pharmacological developments in the hybrid s-triazine moiety: A review Bareth, Diksha
143 C p.
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116 Tailored horseshoe-shaped nicotinonitrile scaffold as dual promising c-Met and Pim-1 inhibitors: Design, synthesis, SAR and in silico study Mohamady, Samy
143 C p.
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117 Targeting JAK2/STAT3 for the treatment of cancer: A review on recent advancements in molecular development using structural analysis and SAR investigations Kohal, Rupali
143 C p.
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118 Tetrahydrobenzothiophene derivatives ameliorate Mia PaCa-2 cell progression and induces apoptosis via inhibiting EGFR2 tyrosine kinase signal Rahman, Abdul
143 C p.
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119 The discovery of a new potent FXR agonist based on natural product screening Yao, Zongwen
143 C p.
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120 Threose nucleic acid as a primitive genetic polymer and a contemporary molecular tool Wang, Juan
143 C p.
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121 Tubulin inhibitors. Selected scaffolds and main trends in the design of novel anticancer and antiparasitic agents Podolak, Magdalena
143 C p.
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                             121 gevonden resultaten
 
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