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                             70 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Acyl-quinic acids from the root bark of Acanthopanax gracilistylus and their inhibitory effects on neutrophil elastase and cyclooxygenase-2 in vitro Yang, Hao-Dong
140 C p.
 artikel
2 4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamide salts: Novel hydrosoluble prodrugs of antimitotics selectively bioactivated by the cytochrome P450 1A1 in breast cancer cells Ouellette, Vincent
140 C p.
 artikel
3 A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different Antioxidants Rashad, Aya Y.
140 C p.
 artikel
4 A novel 68Ga-labeled cyclic peptide molecular probe based on the computer-aided design for noninvasive imaging of PD-L1 expression in tumors Ge, Shushan
140 C p.
 artikel
5 An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives Wang, Xiuli
140 C p.
 artikel
6 BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies Iftikhar, Fizza
140 C p.
 artikel
7 Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism Habib Ullah, Syed
140 C p.
 artikel
8 Cyclometalated iridium(III) complexes induce immunogenic cell death in HepG2 cells via paraptosis Liao, Jiaxin
140 C p.
 artikel
9 Design and synthesis of broad-spectrum antimicrobial amphiphilic peptidomimetics to combat drug-resistance Chen, Yating
140 C p.
 artikel
10 Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors Zhang, Junjie
140 C p.
 artikel
11 Design, synthesis and anti-tumor efficacy evaluation of novel 1,3-diaryl propane-based polyphenols obtained from Claisen rearrangement reaction Jiang, Song-Wei
140 C p.
 artikel
12 Design, synthesis and bioactivity evaluation of selenium-containing PI3Kδ inhibitors Gao, Li
140 C p.
 artikel
13 Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors Long, Zhiwu
140 C p.
 artikel
14 Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77 Hu, Hongyu
140 C p.
 artikel
15 Design, synthesis, and biological evaluation of novel bivalent PI3K inhibitors for the potential treatment of cancer Xia, Liang
140 C p.
 artikel
16 Design, synthesis and evaluation of EZH2-based PROTACs targeting PRC2 complex in lymphoma Xie, Huiru
140 C p.
 artikel
17 Design, synthesis and evaluation of 177Lu-labeled inverso and retro-inverso A9 peptide variants targeting HER2-overexpression Kumar Sharma, Amit
140 C p.
 artikel
18 Design, synthesis, and pharmacological evaluation of quinazoline derivatives as novel and potent pan-JAK inhibitors Xiang, Jinbao
140 C p.
 artikel
19 Development of 4,4′-dibromobinaphthalene analogues with potent photo-inducible DNA cross-linking capability and cytotoxicity towards breast MDA-MB 468 cancer cells Zhang, Qi
140 C p.
 artikel
20 Development of 5-fluorouracil-dichloroacetate mutual prodrugs as anticancer agents Mironiuk-Puchalska, Ewa
140 C p.
 artikel
21 Development of novel HEPT analogs featuring significantly improved anti-resistance potency against HIV-1 through chemical space exploration of the tolerant region I Zhou, Ruo-Lan
140 C p.
 artikel
22 Discovery and identification of a novel PI3K inhibitor with enhanced CDK2 inhibition for the treatment of triple negative breast cancer Yang, Chengbin
140 C p.
 artikel
23 Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity Barbaraci, Carla
140 C p.
 artikel
24 Discovery of hepatoprotective activity components from Thymus quinquecostatus celak. by molecular networking, biological evaluation and molecular dynamics studies Zhong, Xiangjian
140 C p.
 artikel
25 Discovery of new non-covalent and covalent inhibitors targeting SARS-CoV-2 papain-like protease and main protease Liu, Wandong
140 C p.
 artikel
26 Discovery of novel cGAS inhibitors based on natural flavonoids Li, Jiameng
140 C p.
 artikel
27 Editorial Board
140 C p.
 artikel
28 Efficient biosynthesis of Vibegron intermediate using a novel carbonyl reductase based on molecular modification of hydrogen bonding network regulation Zhang, Xiao-Jian
140 C p.
 artikel
29 Evolution of peptide YY analogs for the management of type 2 diabetes and obesity Chen, Wang
140 C p.
 artikel
30 From CPG to hybrid support: Review on the approaches in nucleic acids synthesis in various media Brzezinska, Jolanta
140 C p.
 artikel
31 Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase Weber, Patrick
140 C p.
 artikel
32 Identification and bioactivity evaluation of miliusanes from Miliusa sinensis Xie, Wen-Jian
140 C p.
 artikel
33 Identification and molecular mechanism of novel 5-alkenyl-2-benzylaminothiazol-4(5H)-one analogs as anti-melanogenic and antioxidant agents Kang, Min Kyung
140 C p.
 artikel
34 Imidazopyridine-based kinase inhibitors as potential anticancer agents: A review Peytam, Fariba
140 C p.
 artikel
35 Improving the anti-HIV-1 activity and solubility of poorly water-soluble DAPYs by heteroaromatic replacement strategy: From naphthalene-DAPYs to quinoline-DAPYs Zhou, Ruo-Lan
140 C p.
 artikel
36 Initial study of the detection of ADAM 10 in the urine of type-2 diabetic patients Gruba, Natalia
140 C p.
 artikel
37 Issue TOC
140 C p.
 artikel
38 LC/HRESI-MS/MS screening, phytochemical characterization, and in vitro antioxidant and cytotoxic potential of Jatropha integerrima Jacq. extracts Marzouk, Mohamed
140 C p.
 artikel
39 Lipid droplet-specific near-infrared fluorescent probe for discriminating cancer and normal cells and diagnosing fatty liver Zhang, Yuehua
140 C p.
 artikel
40 Lysosome-targeted fluorescent probes: Design mechanism and biological applications Duan, Xiangning
140 C p.
 artikel
41 Mechanism and antibacterial synergies of poly(Dabco-BBAC) nanoparticles against multi-drug resistant Pseudomonas aeruginosa isolates from human burns Ebadati, Arefeh
140 C p.
 artikel
42 Mechanisms of polydatin against spinal cord ischemia–reperfusion injury based on network pharmacology, molecular docking and molecular dynamics simulation Sun, Zhicheng
140 C p.
 artikel
43 Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells Ma, Ren-Fen
140 C p.
 artikel
44 Metabolism of natural and synthetic bioactive compounds in Cunninghamella fungi and their applications in drug discovery Ibrahim, Abdel-Rahim S.
140 C p.
 artikel
45 Methanesulfonamide derivatives as gastric safe anti-inflammatory agents: Design, synthesis, selective COX-2 inhibitory activity, histopathological and histochemical studies Abdelall, Eman K.A.
140 C p.
 artikel
46 Mn(OAc)2-promoted [3+2] cyclization of enaminone with isocyanoacetate: Rapid access to pyrrole-2-carboxylic ester derivatives with potent anticancer activity Huang, Jiuzhong
140 C p.
 artikel
47 Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigations Husseiny, Ebtehal M.
140 C p.
 artikel
48 Monoterpenoid indole alkaloid dimers from the Melodinus axillaris induce G2/M phase arrest and apoptosis via p38 MAPK activation in HCT116 cells Du, Kaicheng
140 C p.
 artikel
49 Native-compound-Coupled Affinity Matrix (NCAM) in target identification and validation of bioactive compounds: Application, mechanism and outlooks Ma, Lu
140 C p.
 artikel
50 New quinazoline sulfonamide derivatives as potential anticancer agents: Identifying a promising hit with dual EGFR/VEGFR-2 inhibitory and radiosensitizing activity Ghorab, Mostafa M.
140 C p.
 artikel
51 Novel 4-(2-arylidenehydrazineyl)thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico insights Elsebaie, Heba A.
140 C p.
 artikel
52 Novel photoactivated Indole–pyridine chemotherapeutics with strong antimicrobial and antibiofilm activity toward Staphylococcus aureus Zhang, Zhishang
140 C p.
 artikel
53 Peripheral substitution effects on unnatural base pairs: A case of brominated TPT3 to enhance replication fidelity Huo, Bianbian
140 C p.
 artikel
54 Sarcodonol A–D from fruiting bodies of Sarcodon imbricatus inhibits HCoV-OC43 induced apoptosis in MRC-5 cells Jin Yang, Hye
140 C p.
 artikel
55 11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii Xia, Fan
140 C p.
 artikel
56 Selective degradation of BRD4 suppresses lung cancer cell proliferation using GSH-responsive PROTAC precursors Fan, Heli
140 C p.
 artikel
57 Some morpholine tethered novel aurones: Design, synthesis, biological, kinetic and molecular docking studies Saroha, Bhavna
140 C p.
 artikel
58 Spirooxindol alkaloids from Voacanga africana: Targeting biofilm of MBLs producing Escherichia coli Qin, Malong
140 C p.
 artikel
59 Structure-based drug design, synthesis, and biological evaluation of novel 1,3,5-triazine or pyrimidine derivatives containing benzoyl hydrazine moiety as PI3Kα selective inhibitors Fu, Siyu
140 C p.
 artikel
60 Study of G protein-coupled receptors dimerization: From bivalent ligands to drug-like small molecules Qian, Mingcheng
140 C p.
 artikel
61 Synthesis and biological evaluation of carboxamide and quinoline derivatives as P2X7R antagonists Shah, Qasim
140 C p.
 artikel
62 Synthesis and clinical application of small-molecule inhibitors and PROTACs of anaplastic lymphoma kinase Gao, Hua
140 C p.
 artikel
63 Synthesis and evaluation of antibacterial activity of transition metal-oleoyl amide complexes Farhan, Nesrain
140 C p.
 artikel
64 Synthesis and in vitro cytotoxic activity of dye-linker-macrocycle conjugates with variable linker length and components Tomczyk, Mateusz D.
140 C p.
 artikel
65 Synthesis, biological and molecular docking studies of pyrimidine-derived bioactive Schiff bases Manzoor, Saira
140 C p.
 artikel
66 Targeting the epigenetic reader “BET” as a therapeutic strategy for cancer Wahi, Abhishek
140 C p.
 artikel
67 Tinopanoids K-T, clerodane diterpenoids with anti-inflammatory activity from Tinospora crispa Zhu, Yang-Li
140 C p.
 artikel
68 Total syntheses and antibacterial evaluations of cudraflavones A-C and related Flavones Dong, Hongbo
140 C p.
 artikel
69 Unleashing the potential of natural biological peptide Macropin: Hydrocarbon stapling for effective breast cancer treatment Chen, Baobao
140 C p.
 artikel
70 Virtual screening of novel mTOR inhibitors for the potential treatment of human colorectal cancer Zhang, Na-Na
140 C p.
 artikel
                             70 gevonden resultaten
 
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