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                             90 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Aloe emodin-conjugated sulfonyl hydrazones as novel type of antibacterial modulators against S. aureus 25923 through multifaceted synergistic effects Deng, Zhao
127 C p.
 artikel
2 An insight into the interaction between Indisulam and human serum albumin: Spectroscopic method, computer simulation and in vitro cytotoxicity assay Zhou, Bijia
127 C p.
 artikel
3 A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma Yao, Si
127 C p.
 artikel
4 A novel long excitation/emission wavelength fluorophore as platform utilized to construct NIR probes for bioimaging and biosensing Qin, Jingcan
127 C p.
 artikel
5 A novel ratiometric fluorescent probe for the detection and imaging of cysteine in living cells Zheng, Cheng
127 C p.
 artikel
6 Antidiabetic lanostane triterpenoids from the fruiting bodies of Ganoderma weberianum Yang, Li
127 C p.
 artikel
7 Antifungal evaluation and mechanistic investigations of membrane active short synthetic peptides-based amphiphiles Sharma, Komal
127 C p.
 artikel
8 An unprecedented ergostane with a 6/6/5 tricyclic 13(14 → 8)abeo-8,14-seco skeleton from Talaromyces adpressus Zhang, Mi
127 C p.
 artikel
9 Applications of “linkers” in fragment-based drug design Wu, Xin
127 C p.
 artikel
10 Biocatalytic hydrogen-transfer to access enantiomerically pure proxyphylline, xanthinol, and diprophylline Borowiecki, Paweł
127 C p.
 artikel
11 Brujavanoids A–U, structurally diverse apotirucallane-type triterpenoids from Brucea javanica and their anti-inflammatory effects Hu, Zhuo-Fan
127 C p.
 artikel
12 Cadinane-type sesquiterpenoid dimeric diastereomers hibisceusones A-C from infected stems of Hibiscus tiliaceus with cytotoxic activity against triple-negative breast cancer cells Chen, De-Li
127 C p.
 artikel
13 Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease Velueta-Viveros, Martha
127 C p.
 artikel
14 Cardiac glycosides from the roots of Streblus asper Lour. with activity against Epstein-Barr virus lytic replication Cai, Jing
127 C p.
 artikel
15 [11]-chaetoglobosins with cytotoxic activities from Pseudeurotium bakeri Duan, Fangfang
127 C p.
 artikel
16 Corrigendum to “Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity” [Bioorg. Chem. 121 (2022) 105691] Svirčev, Miloš
127 C p.
 artikel
17 Cucurbitane triterpenoid entities derived from Hemsleya penxianensis triggered glioma cell apoptosis via ER stress and MAPK signalling cross-talk Li, Zongyang
127 C p.
 artikel
18 Dehydromevalonolactone ameliorates liver fibrosis and inflammation by repressing activation of NLRP3 inflammasome Niu, Wei-Xiao
127 C p.
 artikel
19 Design and synthesis of novel benzimidazole-iminosugars linked a substituted phenyl group and their inhibitory activities against β-glucosidase Liu, Xu
127 C p.
 artikel
20 Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies Hammouda, Mohamed M.
127 C p.
 artikel
21 Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors Li, Wen
127 C p.
 artikel
22 Design, synthesis and biological evaluation of a series of novel pyrrolo[2,3-d]pyrimidin/pyrazolo[3,4-d]pyrimidin-4-amine derivatives as FGFRs-dominant multi-target receptor tyrosine kinase inhibitors for the treatment of gastric cancer Wu, Xiuli
127 C p.
 artikel
23 Design, synthesis and biological evaluation of N-(4-alkoxy-3-(1H-tetrazol-1-yl)phenyl) heterocyclic aromatic amide derivatives as xanthine oxidase inhibitors Zhang, Ting-jian
127 C p.
 artikel
24 Design, synthesis, characterization and anticancer activity evaluation of deoxycholic acid-chalcone conjugates Patel, Sejal
127 C p.
 artikel
25 Design, synthesis, in vitro, and in silico enzymatic evaluations of thieno[2,3-b]quinoline-hydrazones as novel inhibitors for α-glucosidase Noori, Milad
127 C p.
 artikel
26 Development of a series of novel Mcl-1 inhibitors bearing an indole carboxylic acid moiety Deng, Hongguang
127 C p.
 artikel
27 Dihydroxyphenyl-substituted thiosemicarbazone: A potent scaffold for the development of metallo-β-lactamases inhibitors and antimicrobial Liu, Lu
127 C p.
 artikel
28 Directed evolution of a carbonyl reductase LsCR for the enantioselective synthesis of (1S)-2-chloro-1-(3,4-difluorophenyl) ethanol Liu, Hua-Tao
127 C p.
 artikel
29 Discovery and evaluation of cytisine N-isoflavones as novel EGFR/HER2 dual inhibitors Wang, Yanqing
127 C p.
 artikel
30 Discovery of a novel class of benzoxazole derivatives as histamine H3 receptor ligands for the treatment of neuropathic pain Li, Ziying
127 C p.
 artikel
31 Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors Tian, Ye
127 C p.
 artikel
32 Discovery of carbamate-based N-salicyloyl tryptamine derivatives as novel pleiotropic agents for the treatment of Alzheimer's disease Wang, Yuying
127 C p.
 artikel
33 Discovery of evodiamine derivatives as potential lead antifungal agents for the treatment of superficial fungal infections Liang, Yan
127 C p.
 artikel
34 Discovery of novel 4-arylamino-quinazoline derivatives as EGFRL858R/T790M inhibitors with the potential to inhibit the non-small cell lung cancers Gan, Wenhui
127 C p.
 artikel
35 Diverse polycyclic polyprenylated acylphloroglucinols with anti-neuroinflammatory activity from Hypericum beanii Li, Ya-Wei
127 C p.
 artikel
36 Editorial Board
127 C p.
 artikel
37 Energy metabolism as a target for cyclobenzaprine: A drug candidate against Visceral Leishmaniasis Lima, Marta Lopes
127 C p.
 artikel
38 Evaluation of the cell permeability of bicyclic peptoids and bicyclic peptide-peptoid hybrids Wang, Hee Myeong
127 C p.
 artikel
39 Flavone-1,2,3-triazole derivatives as potential α-glucosidase inhibitors: Synthesis, enzyme inhibition, kinetic analysis and molecular docking study Dhameja, Manoj
127 C p.
 artikel
40 From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitors Wagdy, Reem A.
127 C p.
 artikel
41 Further studies on C2′-substituted 1-phenylbenzazepines as dopamine D1 receptor ligands Giri, Rajan
127 C p.
 artikel
42 Genus Thermotoga: A valuable home of multifunctional glycoside hydrolases (GHs) for industrial sustainability Akram, Fatima
127 C p.
 artikel
43 Heterocyclic ring expansion yields anthraquinone derivatives potent against multidrug resistant tumor cells Tikhomirov, Alexander S.
127 C p.
 artikel
44 Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determination Beytur, Asiye
127 C p.
 artikel
45 Imidazo[4,5-b]pyridine derived tubulin polymerization inhibitors: Design, synthesis, biological activity in vitro and computational analysis Boček, Ida
127 C p.
 artikel
46 Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2′-deoxy-adenosine: Investigation by nucleotide analogues Wu, Junjie
127 C p.
 artikel
47 Investigation of binding mechanism for human plasminogen Kringle 5 with its potential receptor vWA1 domain in Cochlin by bio-specific technologies and molecular dynamic simulation Zhang, Jiaxin
127 C p.
 artikel
48 Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores Yamali, Cem
127 C p.
 artikel
49 Investigation on the potential targets of Astragaloside IV against intracerebral hemorrhage based on network pharmacology and experimental validation Zheng, Yingyi
127 C p.
 artikel
50 (+)-Isocryptotanshinone derivatives and its simplified analogs as STAT3 signaling pathway inhibitors Shi, Xiang
127 C p.
 artikel
51 Isolation, derivatization, in-vitro, and in-silico studies of potent butyrylcholinesterase inhibitors from Berberis parkeriana Schneid Ali, Rabia
127 C p.
 artikel
52 Issue TOC
127 C p.
 artikel
53 Menisperdaurines A-W, structurally diverse isoquinoline alkaloids from Menispermum dauricum and their dopamine D1 receptor activities Wei, Hong-Li
127 C p.
 artikel
54 Modified peroxamide-based reactive oxygen species (ROS)-responsive doxorubicin prodrugs Jafari, Mina
127 C p.
 artikel
55 Nanogel-mediated drug delivery system for anticancer agent: pH stimuli responsive poly(ethylene glycol/acrylic acid) nanogel prepared by gamma irradiation El-Sattar, Nour E.A. Abd
127 C p.
 artikel
56 Nanotechnology applications for treatment of hepatic infections via modulating Hepatic histopathological and DNA alterations Gad, Sameh S.
127 C p.
 artikel
57 Natural product protulactone A: Total synthesis from D-galactose, X-ray analysis and biological evaluation Djokić, Sanja
127 C p.
 artikel
58 New benzimidazole based hybrids: Synthesis, molecular modeling study and anticancer evaluation as TopoII inhibitors Nawareg, Nareman A.
127 C p.
 artikel
59 New dihydrobenzoxanthone derivatives with bacterial neuraminidase inhibitory activity isolated from Artocarpus elasticus Baiseitova, Aizhamal
127 C p.
 artikel
60 New fluorinated diarylureas linked to pyrrolo[2,3-d]pyrimidine scaffold as VEGFR-2 inhibitors: Molecular docking and biological evaluation Adel, Mai
127 C p.
 artikel
61 New phthalimide-based derivatives as EGFR-TK inhibitors: Synthesis, biological evaluation, and molecular modeling study Mansour, Nayera I.
127 C p.
 artikel
62 New thiophene, thienopyridine and thiazoline-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents and multitargeting kinase inhibitors Alamshany, Zahra M.
127 C p.
 artikel
63 Nile crab Potamonautes niloticus shell extract: Chromatographic and molecular elucidation of potent antioxidant and anti-inflammatory capabilities Galal-Khallaf, Asmaa
127 C p.
 artikel
64 Novel chlorpromazine derivatives as anti-endometrial carcinoma agents with reduced extrapyramidal side effects Li, Lijuan
127 C p.
 artikel
65 Novel donepezil-chalcone-rivastigmine hybrids as potential multifunctional anti-Alzheimer's agents: Design, synthesis, in vitro biological evaluation, in vivo and in silico studies Sang, Zhipei
127 C p.
 artikel
66 One pot domino synthesis of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thiones (THTTs) as anti-inflammatory and antinociceptive candidates: A proof from in-vivo to in-vitro and in-silico mechanistic studies Raheem, Sumaya
127 C p.
 artikel
67 Rational drug design strategies for the development of promising multi-target directed indole hybrids as Anti-Alzheimer agents George, Namy
127 C p.
 artikel
68 Recent developments in promiscuous enzymatic reactions for carbon–nitrogen bond formation Xia, Hui
127 C p.
 artikel
69 SAR study culminates in a series of HDAC6 selective inhibitors featuring Schisandrin C-analogous Cap as potential immunomodulatory agents for cancer therapy Tao, Qiangqiang
127 C p.
 artikel
70 Scopariusicides D–M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius Li, Xing-Ren
127 C p.
 artikel
71 Six pairs of enantiomeric phthalide dimers from the rhizomes of Ligusticum chuanxiong and their absolute configurations and anti-inflammatory activities Huang, Lu
127 C p.
 artikel
72 Small molecules enhancers of amyloid aggregation of C-terminal domain of Nucleophosmin 1 in acute myeloid leukemia Florio, Daniele
127 C p.
 artikel
73 Structural and biosynthetic studies of botrycinereic acid, a new cryptic metabolite from the fungus Botrytis cinerea Pinto, Ana A.
127 C p.
 artikel
74 Structurally diverse metabolites from a soil-derived fungus Aspergillus calidoustus Li, Fengli
127 C p.
 artikel
75 Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model Takwale, Akshay D.
127 C p.
 artikel
76 Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells del Rosario, Henoc
127 C p.
 artikel
77 Styryl dyes with N-Methylpiperazine and N-Phenylpiperazine Functionality: AT-DNA and G-quadruplex binding ligands and theranostic agents Zonjić, Iva
127 C p.
 artikel
78 Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell Gong, Xiaobao
127 C p.
 artikel
79 Synthesis and biological evaluation of antibacterial activity of novel clarithromycin derivatives incorporating 1,2,3-triazole moieties at the 4″- and 11-OH positions Qin, Yinhui
127 C p.
 artikel
80 Synthesis and evaluation of avermectin–imidazo[1,2-a]pyridine hybrids as potent GABAA receptor modulators Volkova, Yulia A.
127 C p.
 artikel
81 Synthesis and structure–activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2 Jang, Youngho
127 C p.
 artikel
82 Synthesis, biological evaluation and molecular docking studies of novel diosgenin derivatives as anti-inflammatory agents Zhang, Sheng-Nan
127 C p.
 artikel
83 Synthesis, biological evaluation and structure-activity relationship of 2-(2-hydroxyaryl)alkenylphosphonium salts with potency as anti-MRSA agents Terekhova, Natalia V.
127 C p.
 artikel
84 Synthesis of mitochondria-targeted ferulic acid amide derivatives with antioxidant, anti-inflammatory activities and inducing mitophagy Xie, Yu
127 C p.
 artikel
85 Synthesis of novel 4,7-disubstituted quinoline derivatives as autophagy inducing agents via targeting stabilization of ATG5 Li, Xiangpan
127 C p.
 artikel
86 Synthesis of the new nucleoside 5′-alpha-iminophosphates using Staudinger reaction Vasilyeva, Svetlana V.
127 C p.
 artikel
87 The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia Othman, Esraa M.
127 C p.
 artikel
88 Twelve novel sesquiterpenes with anti-inflammatory and cholesterol-lowering activities from burdock leaves Liang, Hanjing
127 C p.
 artikel
89 Unusual sesquilignans with anti-inflammatory activities from the resin of Ferula sinkiangensis Li, Qian
127 C p.
 artikel
90 Violacein switches off low molecular weight tyrosine phosphatase and rewires mitochondria in colorectal cancer cells Faria, Alessandra V.S.
127 C p.
 artikel
                             90 gevonden resultaten
 
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