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                             47 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 An exit beyond the pharmacophore model for 5-HT6R agents - a new strategy to gain dual 5-HT6/5-HT2A action for triazine derivatives with procognitive potential Kucwaj-Brysz, Katarzyna
121 C p.
 artikel
2 Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3 Brzeminski, Pawel
121 C p.
 artikel
3 Combinatorial assembly, traceless generation and in situ evaluation of inhibitors for therapeutically relevant serine proteases Vu, Lan Phuong
121 C p.
 artikel
4 Design and synthesis of new 2-oxoquinoxalinyl-1,2,4-triazoles as antitumor VEGFR-2 inhibitors Zengin, Merve
121 C p.
 artikel
5 Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease Kaur, Sukhvir
121 C p.
 artikel
6 Design, synthesis and anticancer evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 1,8-naphthyridine-3-carboxamide moiety as novel multi-target TKIs Chen, Pengqin
121 C p.
 artikel
7 Design, synthesis and biological evaluation of 2-aminopyrimidine-based LSD1 inhibitors Wang, Xinran
121 C p.
 artikel
8 Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors Liang, Xiao
121 C p.
 artikel
9 Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors Nie, Wenwen
121 C p.
 artikel
10 Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity Svirčev, Miloš
121 C p.
 artikel
11 Design, synthesis and evaluation of novel thienopyridazine derivatives as Chk1/2 inhibitors Shen, Dadong
121 C p.
 artikel
12 Design, synthesis, biological assessment, and in-Silico studies of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors Mohamed, Heba S.
121 C p.
 artikel
13 Discovery and structural optimization of 9-O-phenylsulfonyl-berberines as new lipid-lowering agents Kong, Yuan
121 C p.
 artikel
14 Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma Li, Baicun
121 C p.
 artikel
15 Discovery of ARS-1620 analogs as KRas G12C inhibitors with high in vivo antitumor activity Zhao, Huiting
121 C p.
 artikel
16 Discovery of EGFR-Targeted Environment-Sensitive fluorescent probes for cell imaging and efficient tumor detection Wang, Li-Xia
121 C p.
 artikel
17 Discovery of new pyrimido[5,4-c]quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies Mekheimer, Ramadan A.
121 C p.
 artikel
18 Discovery of PHGDH inhibitors by virtual screening and preliminary structure–activity relationship study Zhang, Fu-Mao
121 C p.
 artikel
19 Editorial Board
121 C p.
 artikel
20 Evaluation of the effects of natural isoquinoline alkaloids on low density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in hepatocytes, as new potential hypocholesterolemic agents Maharjan, Binita
121 C p.
 artikel
21 Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer Li, Deping
121 C p.
 artikel
22 Fe(III)-catalyzed regioselective and faster synthesis of isocoumarins with 3-oxoalkyl moiety at C-4: Identification of new inhibitors of PDE4 Thirupataiah, B.
121 C p.
 artikel
23 Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach Yen, Shih-Chung
121 C p.
 artikel
24 Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study Olğaç, Simla
121 C p.
 artikel
25 Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction Song, Doona
121 C p.
 artikel
26 Inflammation: Biochemistry, cellular targets, anti-inflammatory agents and challenges with special emphasis on cyclooxygenase-2 Kaur, Baljit
121 C p.
 artikel
27 Interaction between CD44 and highly condensed hyaluronic acid through crosslinking with proteins Tsuji, Reika
121 C p.
 artikel
28 Iridoids and sesquiterpenoids from Valeriana jatamansi and their anti-influenza virus activities Quan, Li-Qiu
121 C p.
 artikel
29 Issue TOC
121 C p.
 artikel
30 Mandelic acid-based spirothiazolidinones targeting M. tuberculosis: Synthesis, in vitro and in silico investigations Trawally, Muhammed
121 C p.
 artikel
31 [99mTc-BBPA]: A possible SPECT agent to understand the role of 18-kDa translocator protein (PBR/TSPO) during neuro-glial interaction Kumari, Neelam
121 C p.
 artikel
32 Novel sulfonyl thiazolyl-hydrazone derivatives as EGFR inhibitors: Design, synthesis, biological evaluation and molecular docking studies Farghaly, Thoraya A.
121 C p.
 artikel
33 One-step purification and immobilization of thermostable β-glucosidase on Na-Y zeolite based on the linker and its application in the efficient production of baohuoside I from icariin Lu, Shan
121 C p.
 artikel
34 Recent developments on 1,8-Naphthalimide moiety as potential target for anticancer agents Tandon, Runjhun
121 C p.
 artikel
35 Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders Singh, Sukhbir
121 C p.
 artikel
36 Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition Corro-Morón, Macarena
121 C p.
 artikel
37 Steroidal saponins from Trillium tschonoskii rhizome repress cancer stemness and proliferation of intrahepatic cholangiocarcinoma Pang, Xu
121 C p.
 artikel
38 Structure-based discovery of a specific SHP2 inhibitor with enhanced blood–brain barrier penetration from PubChem database Ma, Ying
121 C p.
 artikel
39 Structure-dependent of 3-fluorooxindole derivatives interacting with ctDNA: Binding effects and molecular docking approaches Huang, Ze-Yue
121 C p.
 artikel
40 Synthesis and biological evaluation of 6-(pyrimidin-4-yl)-1H-pyrazolo[4,3-b]pyridine derivatives as novel dual FLT3/CDK4 inhibitors Li, Xiandeng
121 C p.
 artikel
41 Synthesis and evaluation of biarylquinoline derivatives as novel HIF-1α inhibitors Wu, Yu-Chieh
121 C p.
 artikel
42 Synthesis, biological evaluation, Structure − Activity relationship studies of quinoline-imidazole derivatives as potent antimalarial agents Roy, Deblina
121 C p.
 artikel
43 Synthesis, photochemistry and computational study of novel 1,2,3-triazole heterostilbenes: Expressed biological activity of their electrocyclization photoproducts Mlakić, Milena
121 C p.
 artikel
44 Synthesis, structural elucidation, in vitro antibacterial activity, DFT calculations, and molecular docking aspects of mixed-ligand complexes of a novel oxime and phenylalanine Korkmaz, Ünal
121 C p.
 artikel
45 Synthesis, structure and acetylcholinesterase inhibition activity of new diarylpyrazoles Zia, Mehwash
121 C p.
 artikel
46 Target identification of anti-diabetic and anti-obesity flavonoid derivative (Fla-CN) Qin, Nan
121 C p.
 artikel
47 Triterpenoids and meroterpenoids from the edible Ganoderma resinaceum and their potential anti-inflammatory, antioxidant and anti-apoptosis activities Kou, Rong-Wei
121 C p.
 artikel
                             47 gevonden resultaten
 
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