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                             67 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Activatable fluorescence molecular imaging and anti-tumor effects investigation of GSH-sensitive BRD4 ligands Zhang, Hang
120 C p.
 artikel
2 A fluorescent probe for monitoring Cys fluctuations in the oxidative stress environment simulated by Cu2+ or H2O2 Wang, Zhuo
120 C p.
 artikel
3 Anti-leukemic effect and molecular mechanism of 11-methoxytabersonine from Melodinus cochinchinensis via network pharmacology, ROS-mediated mitochondrial dysfunction and PI3K/Akt signaling pathway Wang, Yong-Peng
120 C p.
 artikel
4 6-Benzyloxyphthalides as selective and reversible monoamine oxidase B inhibitors with antioxidant and anti-neuroinflammatory activities for Parkinson’s disease treatment Song, Qing
120 C p.
 artikel
5 Bioactive imidamide-based compounds targeted against nitric oxide synthase Arias, Fabio
120 C p.
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6 Caffeine improves the cytotoxic effect of dacarbazine on B16F10 murine melanoma cells Fagundes, Tatiane Renata
120 C p.
 artikel
7 Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins Mottin, Melina
120 C p.
 artikel
8 Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant cancer cells, dual β-tubulin/c-Src inhibition, cell cycle arrest and apoptosis induction Abdelall, Eman K.A.
120 C p.
 artikel
9 Chemoenzymatic enantioselective route to get (+) and (−) 4-acetoxy-azetidin-2-one by lipase-catalysed kinetic resolution and their applications Martelli, Giulia
120 C p.
 artikel
10 Cholinesterase inhibitors assessment of aporphine alkaloids from Annona crassiflora and molecular docking studies Fontes Barbosa, Marília
120 C p.
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11 Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents Nidhar, Manisha
120 C p.
 artikel
12 Combined active pocket and hinge region engineering to develop an NADPH-dependent phenylglycine dehydrogenase Yin, Xinjian
120 C p.
 artikel
13 Comprehensive investigation of binding of some polycyclic aromatic hydrocarbons with bovine serum albumin: Spectroscopic and molecular docking studies Rostamnezhad, Fatemeh
120 C p.
 artikel
14 Corrigendum to “A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants” [Bioorg. Chem. 116 (2021) 105376] Decalf, Jérémie
120 C p.
 artikel
15 Corrigendum to “Design and synthesis of novel isatin-based derivatives targeting cell cycle checkpoint pathways as potential anticancer agents” [Bioorg. Chem. 105 (2020) 104366] Yousef, Mohamed A.
120 C p.
 artikel
16 Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo Ao, Mingtao
120 C p.
 artikel
17 Design and synthesis of the 4H-chromenone derivatives against psoriasis Zhang, Famin
120 C p.
 artikel
18 Design, synthesis, and biological activities of 3-((4,6-diphenylpyrimidin-2-ylamino)methylene)-2,3-dihydrochromen-4-ones Shin, Soon Young
120 C p.
 artikel
19 Design, synthesis and biological evaluation of antitumor platinum(II) agents conjugated with non-steroidal anti-inflammatory drug species Zang, Ju
120 C p.
 artikel
20 Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway Xie, Hong-Xu
120 C p.
 artikel
21 Design, synthesis and molecular docking studies of new azomethine derivatives as promising anti-inflammatory agents Desai, Sulaksha R.
120 C p.
 artikel
22 Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on celecoxib scaffold supported with in vivo anti-inflammatory activity, ulcerogenic liability, ADME profiling and docking study Abdellatif, Khaled R.A.
120 C p.
 artikel
23 Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection Qian, Weiyi
120 C p.
 artikel
24 Design, synthesis, in vitro antiproliferative evaluation and in silico studies of new VEGFR-2 inhibitors based on 4-piperazinylquinolin-2(1H)-one scaffold Hassan, Abdelfattah
120 C p.
 artikel
25 Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling Yıldız, Minhal
120 C p.
 artikel
26 Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist that regulates high-density lipoprotein-cholesterol levels, modulates adipogenesis, and improves glucose tolerance in diet-induced obese mice Dutra, Luiz A.
120 C p.
 artikel
27 Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars Pingitore, Valeria
120 C p.
 artikel
28 Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment Yang, Chao
120 C p.
 artikel
29 Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD) Li, Ling
120 C p.
 artikel
30 Discovery of novel cholic acid derivatives as highly potent agonists for G protein-coupled bile acid receptor Qian, Mingcheng
120 C p.
 artikel
31 Discovery of novel potent covalent inhibitor-based EGFR degrader with excellent in vivo efficacy Shi, Shi
120 C p.
 artikel
32 Discovery, synthesis and exploration of N-benzylsulfonyl-2-phenylazepanes as inhibitors of Bim expression in a mouse embryonic fibroblast model Richards, Benjamin J.
120 C p.
 artikel
33 Editorial Board
120 C p.
 artikel
34 Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agent Liu, Yuanlin
120 C p.
 artikel
35 Enzyme engineering improves catalytic efficiency and enantioselectivity of hydroxynitrile lyase for promiscuous retro-nitroaldolase activity Vishnu Priya, Badipatla
120 C p.
 artikel
36 Harmine-based dual inhibitors targeting histone deacetylase (HDAC) and DNA as a promising strategy for cancer therapy Lu, Dehua
120 C p.
 artikel
37 Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment Elgiushy, Hossam R.
120 C p.
 artikel
38 In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterification Zhang, Mengmeng
120 C p.
 artikel
39 In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa Esharkawy, Eman R.
120 C p.
 artikel
40 Issue TOC
120 C p.
 artikel
41 Lead optimization and biological evaluation of diazenylbenzenesulfonamides inhibitors against glyoxalase-I enzyme as potential anticancer agents Al-Oudat, Buthina A.
120 C p.
 artikel
42 2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response Sun, Moran
120 C p.
 artikel
43 Microwave assisted Biology-Oriented Drug Synthesis (BIODS) of new N,N′-disubstituted benzylamine analogous of 4-aminoantipyrine against leishmaniasis – In vitro assay and in silico-predicted molecular interactions with key metabolic targets Choudhary, Muhammad Iqbal
120 C p.
 artikel
44 New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies Abd El-wahab, Hend A.A.
120 C p.
 artikel
45 New diarylheptanoid dimers as GLP-1 secretagogues and multiple-enzyme inhibitors from Alpinia katsumadai He, Xiao-Feng
120 C p.
 artikel
46 New phosphoramides containing imidazolidine moiety as anticancer agents: An experimental and computational study Gholivand, Khodayar
120 C p.
 artikel
47 New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies Darwish, Sara A.
120 C p.
 artikel
48 Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers Ma, Hongguang
120 C p.
 artikel
49 Novel imidazo[1,2-a]pyridine derivatives as potent ATX allosteric inhibitors: Design, synthesis and promising in vivo anti-fibrotic efficacy in mice lung model Lei, Hongrui
120 C p.
 artikel
50 Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents Liu, Ju
120 C p.
 artikel
51 Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities Gomaa, Hesham A.M.
120 C p.
 artikel
52 Preliminary evaluation of [11C]MAGL-0519 as a promising PET ligand for the diagnosis of Hepatocellular carcinoma Shao, Tuo
120 C p.
 artikel
53 Quinolinyl sulfonamides and sulphonyl esters exhibit inhibitory efficacy against New Delhi metallo-β-lactamase-1 (NDM-1) Chigan, Jia-Zhu
120 C p.
 artikel
54 Rates of competing fluoride elimination and iodination from a thiamin-derived Breslow intermediate Wu, Nathan
120 C p.
 artikel
55 Recent advances in B-RAF inhibitors as anticancer agents Khan, Pathan Shahebaaz
120 C p.
 artikel
56 Recent developments in the management of Huntington's disease Devadiga, Shanaika J.
120 C p.
 artikel
57 RETRACTED: LncRNA SNHG6 facilitates cell proliferation, migration, invasion and EMT by upregulating UCK2 and activating the Wnt/β-catenin signaling in cervical cancer Wei, Jing
120 C p.
 artikel
58 Retraction notice to “LncRNA SNHG6 facilitates cell proliferation, migration, invasion and EMT by upregulating UCK2 and activating the Wnt/ß-catenin signaling in cervical cancer” [Bioorg. Chem. 120 (2022) 105488] Wei, Jing
120 C p.
 artikel
59 Selenourea and thiourea derivatives of chiral and achiral enetetramines: Synthesis, characterization and enzyme inhibitory properties Yiğit, Murat
120 C p.
 artikel
60 Semi-rational protein engineering of a novel esterase from Bacillus aryabhattai (BaCE) for resolution of (R,S)-ethyl indoline-2-carboxylate to prepare (S)-indoline-2-carboxylic acid Zhang, Hongjun
120 C p.
 artikel
61 Structurally diverse glycosides of secoiridoid, bisiridoid, and triterpene-bisiridoid conjugates from the flower buds of two Caprifoliaceae plants and their ATP-citrate lyase inhibitory activities Wan, Jiang
120 C p.
 artikel
62 Structural modification and strategies for the enhanced doxorubicin drug delivery Alam Khan, Shah
120 C p.
 artikel
63 Structures and antitumor activities of ten new and twenty known surfactins from the deep-sea bacterium Limimaricola sp. SCSIO 53532 Ding, Wenping
120 C p.
 artikel
64 Synthesis and in vitro urease inhibitory activity of 5-nitrofuran-2-yl-thiadiazole linked to different cyclohexyl-2-(phenylamino)acetamides, in silico and kinetic studies Asadi, Mehdi
120 C p.
 artikel
65 Synthesis, biological evaluation, pharmacokinetic studies and molecular docking of 4′′′-acetyl-delicaflavone as antitumor agents Li, Shaoguang
120 C p.
 artikel
66 Tamoxifen charge transfer complexes with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and 7,7,8,8-tetracyanoquinodimethan: Synthesis, spectroscopic characterization and theoretical study Mostafa, Gamal A.E.
120 C p.
 artikel
67 VX-11e protects articular cartilage and subchondral bone in osteoarthritis by inhibiting the RIP1/RIP3/MLKL and MAPK signaling pathways Zhang, Weikang
120 C p.
 artikel
                             67 gevonden resultaten
 
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