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                             106 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Activity of the lyases LysSSE1 and HolSSE1 against common pathogenic bacteria and their antimicrobial efficacy in biofilms Lu, Han
116 C p.
 artikel
2 Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonists Reddy, Gangireddy Sujeevan
116 C p.
 artikel
3 An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 Munikishore, Rachakunta
116 C p.
 artikel
4 A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics Al-Hamashi, Ayad A.
116 C p.
 artikel
5 A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants Decalf, Jérémie
116 C p.
 artikel
6 A novel peptidomimetic therapeutic for selective suppression of lung cancer stem cells over non-stem cancer cells Shukla, Satya Prakash
116 C p.
 artikel
7 A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors Yin, Xinjian
116 C p.
 artikel
8 A solid-phase approach for the synthesis of muramyl dipeptide conjugates for detection of NOD2 Kekessie, Ivy
116 C p.
 artikel
9 Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells Mansour, Ghada H.
116 C p.
 artikel
10 Bioactive phenylpropanoid derivatives from the fruits of Lycium ruthenicum Murr Zhao, Sen-Sen
116 C p.
 artikel
11 Biological evaluation and synthesis of calcitroic acid Yu, Olivia B.
116 C p.
 artikel
12 Biotransformations of anthranilic acid and phthalimide to potent antihyperlipidemic alkaloids by the marine-derived fungus Scedosporium apiospermum F41-1 Chen, Pei-Nan
116 C p.
 artikel
13 Bisfischoids A and B, dimeric ent-abietane-type diterpenoids with anti-inflammatory potential from Euphorbia fischeriana Steud. Sun, Cheng-Peng
116 C p.
 artikel
14 Cajamolides A-N: Cytotoxic and anti-inflammatory sesquiterpene lactones from Calea jamaicensis Grafakou, Maria-Eleni
116 C p.
 artikel
15 (±)-Caryopterisines A and B, dimeric monoterpene alkaloids with unprecedented 6/5/5/5/6 pentacyclic rings scaffold from Caryopteris glutinosa Zhang, Xuejian
116 C p.
 artikel
16 Chebulic acid derivatives from Balakata baccata and their antineuroinflammatory and antioxidant activities Zhao, Hai-Yan
116 C p.
 artikel
17 Chemical characterization and multifunctional neuroprotective effects of sesquiterpenoid-enriched Inula britannica flowers extract Tang, Jiang-Jiang
116 C p.
 artikel
18 Concise syntheses and anti-inflammatory effects of isocorniculatolide B and corniculatolide B and C Kim, Taewoo
116 C p.
 artikel
19 Concise total synthesis of (+)-Zeylenone with antitumor activity and the structure–activity relationship of its derivatives Sun, Zhonghao
116 C p.
 artikel
20 Degradable cationic polyesters via ring-opening copolymerization of valerolactones as nanocarriers for the gene delivery Liu, Xu-Ying
116 C p.
 artikel
21 Design and synthesis of curcumin nanostructures: Evaluation of solubility, stability, antibacterial and antioxidant activities Omidi, Sakineh
116 C p.
 artikel
22 Design and synthesis of novel furan, furo[2,3-d]pyrimidine and furo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as potential VEGFR-2 inhibitors Abd El-Mageed, Menna M.A.
116 C p.
 artikel
23 Design and synthesis of novel pyridopyrimidine derivatives with anchoring non-coplanar aromatic extensions of EGFR inhibitory activity Eissa, Amal A.M.
116 C p.
 artikel
24 Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer’s disease Zhang, Panpan
116 C p.
 artikel
25 Design, synthesis and antibacterial activity of chalcones against MSSA and MRSA planktonic cells and biofilms Garcia, Mayara A.R.
116 C p.
 artikel
26 Design, synthesis, and antiviral evaluation of novel piperidine-substituted arylpyrimidines as HIV-1 NNRTIs by exploring the hydrophobic channel of NNIBP Zhang, Tao
116 C p.
 artikel
27 Design, synthesis and bioactive evaluation of geniposide derivatives for antihyperuricemic and nephroprotective effects Wang, Muxuan
116 C p.
 artikel
28 Design, synthesis and bioactivity evaluation of thiazolidinedione derivatives as partial agonists targeting PPARγ Sun, Juan
116 C p.
 artikel
29 Design, synthesis, and biological evaluation of cyano-substituted 2,4-diarylaminopyrimidines as potent JAK3 inhibitors for the treatment of B-cell lymphoma Wu, Bin
116 C p.
 artikel
30 Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy Yue, Kairui
116 C p.
 artikel
31 Design, synthesis, and evaluation of HIV-1 entry inhibitors based on broadly neutralizing antibody 447-52D and gp120 V3loop interactions Senapathi, Jagadeesh
116 C p.
 artikel
32 Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects Amin, Noha H.
116 C p.
 artikel
33 Design, synthesis, and molecular docking study of some 2-((7-chloroquinolin-4-yl) amino) benzohydrazide Schiff bases as potential Eg5 inhibitory agents Kavalapure, Rohini S.
116 C p.
 artikel
34 Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers Sherbiny, Farag F.
116 C p.
 artikel
35 Design, synthesis, stereochemical determination, molecular docking study, in silico pre-ADMET prediction and anti-proliferative activities of indole-pyrimidine derivatives as Mcl-1 inhibitors Lamie, Phoebe F.
116 C p.
 artikel
36 Development of 2′-aminospiro [pyrano[3,2–c]quinoline]-3′-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation Ramadan, Mohamed
116 C p.
 artikel
37 Development of bifunctional anti-PD-L1 antibody MMAE conjugate with cytotoxicity and immunostimulation Xiao, Dian
116 C p.
 artikel
38 Development of pteridin-7(8H)-one analogues as highly potent cyclin-dependent kinase 4/6 inhibitors: Synthesis, structure-activity relationship, and biological activity Li, Qiu
116 C p.
 artikel
39 Development of selective HDAC6 inhibitors with in vitro and in vivo anti-multiple myeloma activity Li, Shunda
116 C p.
 artikel
40 Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors Zhou, Tao-Shun
116 C p.
 artikel
41 Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action Elkamhawy, Ahmed
116 C p.
 artikel
42 Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease Al-Wahaibi, Lamya H.
116 C p.
 artikel
43 Diterpenoid glucosides with cystathionine γ-lyase inhibitory activity from Tinospora sinensis Zhang, Jun-Sheng
116 C p.
 artikel
44 Diterpenoid glycosides from the flower of Trollius chinensis Bunge and their nitric oxide inhibitory activities Guo, Mei-Li
116 C p.
 artikel
45 Double-edged Swords: Diaryl pyrazoline thiazolidinediones synchronously targeting cancer epigenetics and angiogenesis Upadhyay, Neha
116 C p.
 artikel
46 Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer’s disease Manzoor, Shoaib
116 C p.
 artikel
47 Editorial Board
116 C p.
 artikel
48 Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress Sharma, Bharti
116 C p.
 artikel
49 Euphorfistrines A-G, cytotoxic and AChE inhibiting triterpenoids from the roots of Euphorbia fischeriana Wei, Jiang-Chun
116 C p.
 artikel
50 Exploration of brominated Plastoquinone analogs: Discovery and structure-activity relationships of small antimicrobial lead molecules Yıldız, Mahmut
116 C p.
 artikel
51 Exploration of novel anti-angiogenic PEDF-derived peptides with improved activitives by inhibiting proliferation, suppressing migration, and inducing 67LR internalization Shi, Wei
116 C p.
 artikel
52 Exploration of the 2,3-dihydroisoindole pharmacophore for inhibition of the influenza virus PA endonuclease Rogolino, Dominga
116 C p.
 artikel
53 Extraction, structural characterization, and antioxidant and immunomodulatory activities of a polysaccharide from Notarchus leachii freeri eggs Pan, Qiting
116 C p.
 artikel
54 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure–activity relationships Kunwar, Surendra
116 C p.
 artikel
55 FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma Peng, Xing-Rong
116 C p.
 artikel
56 Hybrids of 4-hydroxy derivatives of goniothalamin and piplartine bearing a diester or a 1,2,3-triazole linker as antiproliferative agents Grigolo, Thiago A.
116 C p.
 artikel
57 Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies against MRSA Ibrahim, Seham A.
116 C p.
 artikel
58 Identification of N,N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization Della Volpe, S.
116 C p.
 artikel
59 Interactions of isoorientin and its Semi-synthetic analogs with human serum albumin Wang, Wenliang
116 C p.
 artikel
60 Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference Baussanne, Isabelle
116 C p.
 artikel
61 In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents Fayed, Eman A.
116 C p.
 artikel
62 Isatin-hydrazide conjugates as potent α-amylase and α-glucosidase inhibitors: Synthesis, structure and invitro evaluations Abbasi, Inzamam
116 C p.
 artikel
63 Issue TOC
116 C p.
 artikel
64 Microtubule associated proteins as targets for anticancer drug development Khwaja, Sadiya
116 C p.
 artikel
65 α-naphthoflavone-derived cytochrome P450 (CYP)1B1 degraders specific for sensitizing CYP1B1-mediated drug resistance to prostate cancer DU145: Structure activity relationship Chen, Peng
116 C p.
 artikel
66 New dammarane-type triterpenoid saponins from Gynostemma pentaphyllum and their Sirt1 agonist activity Lou, Yun-Yun
116 C p.
 artikel
67 New dimeric phloroglucinol derivatives from Agrimonia pilosa and their hepatoprotective activities Zhang, Jia
116 C p.
 artikel
68 Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 Yao, Zhai-Wen
116 C p.
 artikel
69 Novel cinnamic acid magnolol derivatives as potent α-glucosidase and α-amylase inhibitors: Synthesis, in vitro and in silico studies Hu, Chun-Mei
116 C p.
 artikel
70 Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects Hendawy, O.M.
116 C p.
 artikel
71 Novel inhibitors of eukaryotic elongation factor 2 kinase: In silico, synthesis and in vitro studies Onder, Ferah Comert
116 C p.
 artikel
72 Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study Krátký, Martin
116 C p.
 artikel
73 Panaxadiol as a major metabolite of AD-1 can significantly inhibit the proliferation and migration of breast cancer cells: In vitro and in vivo study Xu, Lei
116 C p.
 artikel
74 Pharmacophore based drug design and synthesis of oxindole bearing hybrid as anticancer agents Pathak, Ankita
116 C p.
 artikel
75 Piperazine-Coumarin based fluorescence probe with enhanced brightness and solubility for bio-thiol detection and esophageal carcinoma diagnosis Ma, Junyan
116 C p.
 artikel
76 Polyketone metabolites isolated from Rhodiola tibetica endohytic fungus Alternaria sp. HJT-Y7 and their SARS-CoV-2 virus inhibitory activitives Lu, Xuan
116 C p.
 artikel
77 Probing the helical stability in a VEGF-mimetic peptide De Rosa, Lucia
116 C p.
 artikel
78 Recent advances on the intervention sites targeting USP7-MDM2-p53 in cancer therapy Harakandi, Chrisanta
116 C p.
 artikel
79 Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu Tang through a new technique of reverse finding target Wang, Zixuan
116 C p.
 artikel
80 Selective CDK4/6 inhibition of novel 1,2,3-triazole tethered acridinedione derivatives induces G1/S cell cycle transition arrest via Rb phosphorylation blockade in breast cancer models Praveenkumar, E.
116 C p.
 artikel
81 Spectroscopic and Small-angle X-ray scattering analysis of binding between Copper(II) −1-allylimidazole complex, a potential anti-tumor agent, and bovine serum albumin Gałczyńska, Katarzyna
116 C p.
 artikel
82 Structural definition of the discrete hotspot sites of BMP-2 conformational wrist epitope and rational design of the hotspot-derived osteogenic peptides against chondrocyte senescence Zhang, Wei
116 C p.
 artikel
83 Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains Akunuri, Ravikumar
116 C p.
 artikel
84 Synthesis and biological assessment of new pyrimidopyrimidines as inhibitors of breast cancer resistance protein (ABCG2) Dakhlaoui, Imen
116 C p.
 artikel
85 Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors Meng, Xiang-Dong
116 C p.
 artikel
86 Synthesis and biological evaluation of heterocyclic ring-fused dammarane-type ginsenoside derivatives as potential anti-tumor agents Ma, Lu
116 C p.
 artikel
87 Synthesis and biological evaluation of NO-donor containing photosensitizers to induce ferroptosis of cancer cells Guo, Xiuhan
116 C p.
 artikel
88 Synthesis and biological evaluation of zwitterionic half-sandwich Rhodium(III) and Ruthenium(II) organometallic complexes Guo, Lihua
116 C p.
 artikel
89 Synthesis and evaluation of antitumor activity of 9-methoxy-1H-benzo[f]chromene derivatives El Gaafary, Menna
116 C p.
 artikel
90 Synthesis and evaluation of 3-(phenylethynyl)-1,1′-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors Wang, Shisheng
116 C p.
 artikel
91 Synthesis and in vitro and in silico studies of 1H- and 2H-1,2,3-triazoles as antichagasic agents Silva, Thais B.
116 C p.
 artikel
92 Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents Song, Zilan
116 C p.
 artikel
93 Synthesis, antimicrobial activity and cytotoxicity of triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl nucleoside analogues Yu. Strobykina, Irina
116 C p.
 artikel
94 Synthesis, characterization and biological evaluation of indomethacin derived thioureas as purinergic (P2Y1, P2Y2, P2Y4, and P2Y6) receptor antagonists Bano, Sehrish
116 C p.
 artikel
95 Synthesis, characterization, in vitro cholinesterase and hRBCs hemolysis assay and computational evaluation of novel 2,3,4,5-tetrahydrobenzothiazepine appended α-aminophosphonates Shaikh, Sarfaraz
116 C p.
 artikel
96 Synthesis, in vitro anticancer activity and in silico studies of certain isoxazole-based carboxamides, ureates, and hydrazones as potential inhibitors of VEGFR2 Abou-Seri, Sahar M.
116 C p.
 artikel
97 Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs) Mohammed, Esraa Z.
116 C p.
 artikel
98 Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines Jacques, Amanda Virtuoso
116 C p.
 artikel
99 Synthesis of α-l-Araf and β-d-Galf series furanobiosides using mutants of a GH51 α-l-arabinofuranosidase Zhao, Jiao
116 C p.
 artikel
100 Synthesis of N-methylpyridine-chlorofuranformamide analogs as novel OPG up-regulators and inhibitors of RANKL-induced osteoclastogenesis Liu, Chao
116 C p.
 artikel
101 Synthesis of novel calcium channel blockers with ACE2 inhibition and dual antihypertensive/anti-inflammatory effects: A possible therapeutic tool for COVID-19 Mahgoub, Shahenda
116 C p.
 artikel
102 The AMPA receptor biophysical gating properties and binding site: Focus on novel curcumin-based diazepines as non-competitive antagonists Qneibi, Mohammad
116 C p.
 artikel
103 Transforming Type II to Type I c-Met kinase inhibitors via combined scaffold hopping and structure-guided synthesis of new series of 1,3,4-thiadiazolo[2,3-c]-1,2,4-triazin-4-one derivatives El-Wakil, Marwa H.
116 C p.
 artikel
104 Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' Chen, Jing
116 C p.
 artikel
105 Ulmoidol, an unusual nortriterpenoid from Eucommia ulmoides Oliv. Leaves prevents neuroinflammation by targeting the PU.1 transcriptional signaling pathway Han, Rui
116 C p.
 artikel
106 Water-soluble matrine-type alkaloids with potential anti-neuroinflammatory activities from the seeds of Sophora alopecuroides Luo, Ding
116 C p.
 artikel
                             106 gevonden resultaten
 
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