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                             64 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 8-Alkylmercaptocaffeine derivatives: antioxidant, molecular docking, and in-vitro cytotoxicity studies Sargazi, Saman
111 C p.
 artikel
2 Antiproliferative and cytotoxic activities of C-Geranylated flavonoids from Paulownia tomentosa Steud. Fruit Molčanová, Lenka
111 C p.
 artikel
3 Biomimetic synthesis and anti-inflammatory evaluation of violacin A analogues Wu, Wenxi
111 C p.
 artikel
4 Blended polar/nonpolar peptide conjugate interferes with human insulin amyloid-mediated cytotoxicity Sen, Shantanu
111 C p.
 artikel
5 Butyrolactone and sesquiterpene derivatives as inhibitors of iNOS from the roots of Lindera glauca Ruan, Qing-Feng
111 C p.
 artikel
6 Chemical space exploration of novel naphthyl-carboxamide-diarylpyrimidine derivatives with potent anti-HIV-1 activity Sang, Yali
111 C p.
 artikel
7 Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule Egyed, Attila
111 C p.
 artikel
8 Design and linkage optimization of ursane-thalidomide-based PROTACs and identification of their targeted-degradation properties to MDM2 protein Qi, Zhiwen
111 C p.
 artikel
9 Design and synthesis of β-carboline and combretastatin derivatives as anti-neutrophilic inflammatory agents Kumar, Sunil
111 C p.
 artikel
10 Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability Ihmaid, Saleh K.
111 C p.
 artikel
11 Design, synthesis and antitumor activity evaluation of Chrysamide B derivatives Zhu, Longqing
111 C p.
 artikel
12 Design, synthesis, and biological activity evaluation of a series of novel sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia Feng, Ziying
111 C p.
 artikel
13 Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway Ma, Yingying
111 C p.
 artikel
14 Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile Abdel-Aziz, Salah A.
111 C p.
 artikel
15 Design, synthesis and biological evaluation of novel bischalcone derivatives as potential anticancer agents Burmaoglu, Serdar
111 C p.
 artikel
16 Design, synthesis and biological evaluation of selective histone deacetylase 6 (HDAC6) inhibitors bearing benzoindazole or pyrazoloindazole scaffold as surface recognition motif Xu, Qihao
111 C p.
 artikel
17 Design, synthesis and evaluation of cholinesterase hybrid inhibitors using a natural steroidal alkaloid as precursor Borioni, José L.
111 C p.
 artikel
18 Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer’s disease Choubey, Priyanka Kumari
111 C p.
 artikel
19 Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer’s disease agents Ye, Chanyuan
111 C p.
 artikel
20 Design, synthesis and in vivo anticancer activity of novel parthenolide and micheliolide derivatives as NF-κB and STAT3 inhibitors Zeng, Binglin
111 C p.
 artikel
21 Design, synthesis and mechanistic study of new 1,2,4-triazole derivatives as antimicrobial agents Amin, Noha H.
111 C p.
 artikel
22 Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity Abd El-Karim, Somaia S.
111 C p.
 artikel
23 Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment Marzouk, Adel A.
111 C p.
 artikel
24 Design, synthesis, modelling studies and biological evaluation of 1,3,4-oxadiazole derivatives as potent anticancer agents targeting thymidine phosphorylase enzyme Bajaj, Shalini
111 C p.
 artikel
25 Discovery of nor-bicyclic polyprenylated acylphloroglucinols possessing diverse architectures with anti-hepatoma activities from Hypericum patulum Duan, Yulin
111 C p.
 artikel
26 Discovery of novel celastrol-triazole derivatives with Hsp90-Cdc37 disruption to induce tumor cell apoptosis Li, Na
111 C p.
 artikel
27 Discovery of novel dihydroartemisinin-cinnamic hybrids inducing lung cancer cells apoptosis via inhibition of Akt/Bad signal pathway Hu, Yanping
111 C p.
 artikel
28 Discovery of pyridine- sulfonamide hybrids as a new scaffold for the development of potential VEGFR-2 inhibitors and apoptosis inducers Ahmed, Marwa F.
111 C p.
 artikel
29 Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents Zhang, Cong
111 C p.
 artikel
30 Dysiscalarones A-E, scalarane sesterterpenoids with nitric oxide production inhibitory activity from marine sponge Dysidea granulosa Sun, Jia-Bao
111 C p.
 artikel
31 Editorial Board
111 C p.
 artikel
32 Exploring the quorum sensing inhibition of isolated chrysin from Penicillium chrysogenum DXY-1 Chang, Aiping
111 C p.
 artikel
33 Ginsenoside derivatives inhibit advanced glycation end-product formation and glucose–fructose mediated protein glycation in vitro via a specific structure–activity relationship Yousof Ali, Md
111 C p.
 artikel
34 α-Glucosidase inhibitory and anti-inflammatory activities of dammarane triterpenoids from the leaves of Cyclocarya paliurus Li, Chenguo
111 C p.
 artikel
35 α-Glucosidase inhibitory triterpenoids from Euonymus fortunei Zhao, Ke
111 C p.
 artikel
36 Granatripodins A–B, limonoids featuring a Tricyclo[3.3.1.02,8]nonane motif: Absolute configuration and agonistic effects on human pregnane–X–receptor Shen, Li
111 C p.
 artikel
37 High-level expression of a novel multifunctional GH3 family β-xylosidase/α-arabinosidase/β-glucosidase from Dictyoglomus turgidum in Escherichia coli Tong, Xinyi
111 C p.
 artikel
38 Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) Potenza, Marianna
111 C p.
 artikel
39 In vitro and in vivo degradation of programmed cell death ligand 1 (PD-L1) by a proteolysis targeting chimera (PROTAC) Wang, Yubo
111 C p.
 artikel
40 Issue TOC
111 C p.
 artikel
41 Lithocholic acid-based design of noncalcemic vitamin D receptor agonists Gaikwad, Sunil
111 C p.
 artikel
42 New benzimidazolequinones as trypanosomicidal agents López-Lira, Claudia
111 C p.
 artikel
43 New dammarane-type glycosides from Gynostemma pentaphyllum and their lipid-lowering activity Weng, Xin
111 C p.
 artikel
44 New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways Batran, Rasha Z.
111 C p.
 artikel
45 Novel antibody-drug conjugate with UV-controlled cleavage mechanism for cytotoxin release Li, Jiaguo
111 C p.
 artikel
46 Novel 4,5-dihydrospiro[benzo[c]azepine-1,1′-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation Li, Shuai
111 C p.
 artikel
47 Novel inhibitors of the main protease enzyme of SARS-CoV-2 identified via molecular dynamics simulation-guided in vitro assay Loschwitz, Jennifer
111 C p.
 artikel
48 Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study Ibrahim, Tarek S.
111 C p.
 artikel
49 Novel 1,2,3-triazole-tethered Pam3CAG conjugates as potential TLR-2 agonistic vaccine adjuvants Mhamane, Tukaram B.
111 C p.
 artikel
50 Oxygenated pentacyclic triterpenoids from the stems and branches of Enkianthus chinensis Wang, Hai-Qiang
111 C p.
 artikel
51 Phenylpropanoid-conjugated pentacyclic triterpenoids from the whole plants of Leptopus lolonum induced cell apoptosis via MAPK and Akt pathways in human hepatocellular carcinoma cells Qi, Shi-Zhou
111 C p.
 artikel
52 Small organic molecules accelerate the expansion of regulatory T cells Afridi, Saifullah
111 C p.
 artikel
53 Structurally diverse diterpenoids with eight carbon skeletons from Rhododendron micranthum and their antinociceptive effects Jin, Pengfei
111 C p.
 artikel
54 Structure and cytotoxicity of trichothecenes produced by the potato-associated fungus Trichothecium crotocinigenum Yang, Hui-Xiang
111 C p.
 artikel
55 Synthesis and evaluation of technetium-99m labelled 1-(2-methoxyphenyl)piperazine derivative for single photon emission computed tomography imaging for targeting 5-HT1A Kumari, Neelam
111 C p.
 artikel
56 Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors Thapa Magar, Til Bahadur
111 C p.
 artikel
57 Synthesis, antioxidant activity and bioinformatics studies of L-3-hydroxytyrosine templated N-alkyl/aryl substituted urea/thioureas Kollu, Umapriya
111 C p.
 artikel
58 Synthesis, in vitro evaluation, and molecular docking studies of novel hydrazineylideneindolinone linked to phenoxymethyl-1,2,3-triazole derivatives as potential α-glucosidase inhibitors Shareghi-Boroujeni, Diba
111 C p.
 artikel
59 Synthesis, molecular modeling, selective aldose reductase inhibition and hypoglycemic activity of novel meglitinides Salem, Manar G.
111 C p.
 artikel
60 Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches Boraei, Ahmed T.A.
111 C p.
 artikel
61 The discovery of novel sanjuanolide derivatives as chemotherapeutic agents targeting castration-resistant prostate cancer Wang, Guangbao
111 C p.
 artikel
62 Therapeutic effect of cold atmospheric plasma and its combination with radiation as a novel approach on inhibiting cervical cancer cell growth (HeLa cells) Kenari, Ali Jamaati
111 C p.
 artikel
63 The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors Yang, Hao
111 C p.
 artikel
64 Tuning NO release of organelle-targeted furoxan derivatives and their cytotoxicity against lung cancer cells Sodano, Federica
111 C p.
 artikel
                             64 gevonden resultaten
 
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