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                             104 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors Ahmad, Haseen
105 C p.
 artikel
2 Advanced glycation end-products (AGE) trapping agents: Design and synthesis of nature inspired indeno[2,1-c]pyridinones Anaga, Nair
105 C p.
 artikel
3 An allomaltol derivative triggers distinct death pathways in luminal a and triple-negative breast cancer subtypes Ercan, A.
105 C p.
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4 An insight into medicinal attributes of dithiocarbamates: Bird’s eye view Shinde, Sangita Dattatray
105 C p.
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5 Antibacterial activities of sulfonyl or sulfonamide containing heterocyclic derivatives and its structure-activity relationships (SAR) studies: A critical review Kumar Verma, Santosh
105 C p.
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6 Antileishmanial activity of 4-phenyl-1-[2-(phthalimido-2-yl)ethyl]-1H-1,2,3-triazole (PT4) derivative on Leishmania amazonensis and Leishmania braziliensis: In silico ADMET, in vitro activity, docking and molecular dynamic simulations Holanda, Vanderlan Nogueira
105 C p.
 artikel
7 Antioxidant activity and inhibition of ultraviolet radiation-induced skin damage of Selenium-rich peptide fraction from selenium-rich yeast protein hydrolysate Guo, Hengke
105 C p.
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8 Antioxidant compounds from Banisteriopsis argyrophylla leaves as α-amylase, α-glucosidase, lipase, and glycation inhibitors Quaresma, Daiane M.O.
105 C p.
 artikel
9 Asperochratides A–J, Ten new polyketides from the deep-sea-derived Aspergillus ochraceus Zou, Zheng-Biao
105 C p.
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10 Batzelladine D and norbatzelladine L purified from marine sponge Monanchora arbuscula induce the reversal of fluconazole Domingos, Levy T.S.
105 C p.
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11 Bioactive daphnane diterpenes from Wikstroemia chuii with their potential anti-inflammatory effects and anti-HIV activities Liu, Yun-Yao
105 C p.
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12 Briarane-type diterpenoids from a gorgonian coral Ellisella sp. with anti-HBV activities Wu, Jiru
105 C p.
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13 Colletotrichalactones A-Ca, unusual 5/6/10-fused tricyclic polyketides produced by an endophytic fungus, Colletotrichum sp. JS-0361 Bang, Sunghee
105 C p.
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14 Coumarin-based fluorescent biosensor with large linear range for ratiometric measurement of intracellular pH Iacopini, Dalila
105 C p.
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15 Cytotoxic secondary metabolites from the vulnerable conifer Cephalotaxus oliveri and its associated endophytic fungus Alternaria alternate Y-4-2 Ma, Guang-Lei
105 C p.
 artikel
16 Design and synthesis of aryl-substituted pyrrolidone derivatives as quorum sensing inhibitors Liu, Zhiyang
105 C p.
 artikel
17 Design and synthesis of new pyranoquinolinone heteroannulated to triazolopyrimidine of potential apoptotic antiproliferative activity Ramadan, Mohamed
105 C p.
 artikel
18 Design and synthesis of novel isatin-based derivatives targeting cell cycle checkpoint pathways as potential anticancer agents Yousef, Mohamed A.
105 C p.
 artikel
19 Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy Ibrahim, Tarek S.
105 C p.
 artikel
20 Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance Gu, Xinjie
105 C p.
 artikel
21 Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors Ismail, Magda M.F.
105 C p.
 artikel
22 Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity Tokala, Ramya
105 C p.
 artikel
23 Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity Nemr, Mohamed T.M.
105 C p.
 artikel
24 Design, synthesis and antitumor activity of icotinib derivatives Mao, Longfei
105 C p.
 artikel
25 Design, synthesis and biological assessment of acridine derivatives containing 1,3,4-thiadiazole moiety as novel selective acetylcholinesterase inhibitors Lotfi, Safa
105 C p.
 artikel
26 Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor Fan, Qing-Zhu
105 C p.
 artikel
27 Design, synthesis and biological evaluation of anticholinesterase peptides: Fragment-based vs. template-based peptide design Tahmasebi, Elahe
105 C p.
 artikel
28 Design, synthesis and biological evaluation of new series of hexahydroquinoline and fused quinoline derivatives as potent inhibitors of wild-type EGFR and mutant EGFR (L858R and T790M) Shaheen, Mennatallah A.
105 C p.
 artikel
29 Design, synthesis and biological evaluation of novel arylpropionic esters for the treatment of acute kidney injury Zuo, Jiawei
105 C p.
 artikel
30 Design, synthesis and biological evaluation of novel 7H-benzo [c] [1, 3] dioxolo [4, 5-f] chromen-7-one derivatives with potential anti-tumor activity Zhou, Shiyang
105 C p.
 artikel
31 Design, synthesis and biological evaluation of novel 4-phenoxypyridine based 3-oxo-3,4-dihydroquinoxaline-2-carboxamide derivatives as potential c-Met kinase inhibitors Wang, Zhen
105 C p.
 artikel
32 Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker Zhang, Guang-Yu
105 C p.
 artikel
33 Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway Szeliga, Monika
105 C p.
 artikel
34 Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors Mohamed, Mamdouh F.A.
105 C p.
 artikel
35 Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers Amin, Noha H.
105 C p.
 artikel
36 Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators Carullo, Gabriele
105 C p.
 artikel
37 Design, synthesis, biological evaluation and in silico studies of certain aryl sulfonyl hydrazones conjugated with 1,3-diaryl pyrazoles as potent metallo-β-lactamase inhibitors Shaaban, Marwa M.
105 C p.
 artikel
38 Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors El-Adl, Khaled
105 C p.
 artikel
39 2,4-Diketo esters: Crucial intermediates for drug discovery Joksimović, Nenad
105 C p.
 artikel
40 Discovery of cell-internalizing artificial nucleic acid aptamers for lung fibroblasts and targeted drug delivery Uemachi, Hiro
105 C p.
 artikel
41 Discovery of dipeptidyl peptidase 4 inhibitory peptides from Largemouth bass (Micropterus salmoides) by a comprehensive approach Wang, Kai
105 C p.
 artikel
42 Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2 Zhao, Yi-Shu
105 C p.
 artikel
43 Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation Eissa, Ibrahim H.
105 C p.
 artikel
44 Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity Al-Hussain, Sami A.
105 C p.
 artikel
45 Discovery of novel sulfonamide-containing aminophosphonate derivatives as selective COX-2 inhibitors and anti-tumor candidates Zhang, Bo
105 C p.
 artikel
46 Diterpenoids and triterpenoids from Triadica rotundifolia and their effects on microglial nitric oxide production Zhao, Hai-Yan
105 C p.
 artikel
47 Dual active 1, 4-dihydropyridine derivatives: Design, green synthesis and in vitro anti-cancer and anti-oxidant studies Anaikutti, Parthiban
105 C p.
 artikel
48 Editorial Board
105 C p.
 artikel
49 Effects of different ester chains on the antioxidant activity of caffeic acid Zheng, Yan-Zhen
105 C p.
 artikel
50 Efficacy of novel methylenecyclohexenone derivatives as TrxR inhibitors in suppressing the proliferation and metastasis of human cancer cells Meng, Chi
105 C p.
 artikel
51 Flavonoid analogues as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation Liu, Honghui
105 C p.
 artikel
52 Flavonoids from Barnebydendron riedelii leaf extract mitigate thioacetamide-induced hepatic encephalopathy in rats: The interplay of NF-κB/IL-6 and Nrf2/HO-1 signaling pathways Baraka, Sara M.
105 C p.
 artikel
53 Herqueilenone A, a unique rearranged benzoquinone-chromanone from the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729 Yu, Jae Sik
105 C p.
 artikel
54 Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors Li, Jia-Qi
105 C p.
 artikel
55 HZ-A-005, a potent, selective, and covalent Bruton’s tyrosine kinase inhibitor in preclinical development Huang, Wenhai
105 C p.
 artikel
56 Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities Choi, Ji Won
105 C p.
 artikel
57 Identification of a potent and selective phosphatidylinositol 3-kinase δ inhibitor for the treatment of non-Hodgkin's lymphoma Zuo, Wei-Qiong
105 C p.
 artikel
58 Identification of novel inhibitors of the ABC transporter BmrA Serçinoğlu, Onur
105 C p.
 artikel
59 Identification of quinoline-chalcones and heterocyclic chalcone-appended quinolines as broad-spectrum pharmacological agents Atukuri, Dorababu
105 C p.
 artikel
60 Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization Vitale, Rosa Maria
105 C p.
 artikel
61 Inhibition of Aβ aggregates in Alzheimer’s disease by epigallocatechin and epicatechin-3-gallate from green tea Chen, Tingting
105 C p.
 artikel
62 Inhibition of histone deacetylases, topoisomerases and epidermal growth factor receptor by metal-based anticancer agents: Design & synthetic strategies and their medicinal attributes Kaur, Manpreet
105 C p.
 artikel
63 Investigation of serum and brain superoxide dismutase levels depending on atomoxetine used in attention-deficit/hyperactivity disorder treatment: A combination of in vivo and molecular docking studies Gür, Fatma
105 C p.
 artikel
64 Issue TOC
105 C p.
 artikel
65 Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis Chen, Yan-Ni
105 C p.
 artikel
66 Measurement of oxidized albumin: An opportunity for diagnoses or treatment of COVID-19 Rahmani-Kukia, Nasim
105 C p.
 artikel
67 Modified lanostane-type triterpenoids with neuroprotective effects from the fungus Inonotus obliquus Zou, Chun-Xin
105 C p.
 artikel
68 Nano-sized formazan analogues: Synthesis, structure elucidation, antimicrobial activity and docking study for COVID-19 Mahmoud, Huda K.
105 C p.
 artikel
69 Neuroprotective schinortriterpenoids with diverse scaffolds from Schisandra henryi He, Tao-Bin
105 C p.
 artikel
70 Neurotrophic and anti-neuroinflammatory constituents from the aerial parts of Coriandrum sativum Cha, Joon Min
105 C p.
 artikel
71 New chalcone-tethered 1,3,5-triazines potentiate the anticancer effect of cisplatin against human lung adenocarcinoma A549 cells by enhancing DNA damage and cell apoptosis El-Wakil, Marwa H.
105 C p.
 artikel
72 New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study Farrag, Amel M.
105 C p.
 artikel
73 New insight into enzymatic hydrolysis of peptides with site-specific amino acid d-isomerization Yan, Liang
105 C p.
 artikel
74 Novel 3,4-dihydroquinolin-2(1H)-one derivatives as dual inhibitor targeting AKR1B1/ROS for treatment of diabetic complications: Design, synthesis and biological evaluation Han, Zhongfei
105 C p.
 artikel
75 Novel Linezolid analogues with antiparasitic activity against Hymenolepis nana Alcántar-Zavala, Eleazar
105 C p.
 artikel
76 Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity Gomaa, Hesham A.M.
105 C p.
 artikel
77 Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents Xu, Chenhao
105 C p.
 artikel
78 Novel ureido-dihydropyridine scaffolds as theranostic agents Auria-Luna, Fernando
105 C p.
 artikel
79 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors Naz, Fouzia
105 C p.
 artikel
80 Phenolic bisabolane and cuparene sesquiterpenoids with anti-inflammatory activities from the deep-sea-derived Aspergillus sydowii MCCC 3A00324 fungus Niu, Siwen
105 C p.
 artikel
81 Platinum(IV) complexes conjugated with chalcone analogs as dual targeting anticancer agents: In vitro and in vivo studies Huang, Xiaochao
105 C p.
 artikel
82 Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies Petrović, Milena M.
105 C p.
 artikel
83 Probing sulphamethazine and sulphamethoxazole based Schiff bases as urease inhibitors; synthesis, characterization, molecular docking and ADME evaluation Hamad, Asad
105 C p.
 artikel
84 Prodrugs for nitroreductase based cancer therapy-4: Towards prostate cancer targeting: Synthesis of N-heterocyclic nitro prodrugs, Ssap-NtrB enzymatic activation and anticancer evaluation Güngör, Tuğba
105 C p.
 artikel
85 Scaffold-based selective SHP2 inhibitors design using core hopping, molecular docking, biological evaluation and molecular simulation Li, Wei-Ya
105 C p.
 artikel
86 Sesquiterpene lactone dimers from Artemisia lavandulifolia inhibit interleukin-1β production in macrophages through activating autophagy Wang, Qiaoqiao
105 C p.
 artikel
87 Synthesis and antioxidant activity of conjugates of hydroxytyrosol and coumarin Li, Wen-Bo
105 C p.
 artikel
88 Synthesis and anti-parasitic activity of N-benzylated phosphoramidate Mg2+-chelating ligands Adeyemi, Christiana M.
105 C p.
 artikel
89 Synthesis and biological assessment of ciprofloxacin-derived 1,3,4-thiadiazoles as anticancer agents Ahadi, Hamideh
105 C p.
 artikel
90 Synthesis and controlled drug delivery studies of a novel Ubiquinol-Polyethylene glycol-Vitamin E adduct Cateni, Francesca
105 C p.
 artikel
91 Synthesis and discovery of ω-3 polyunsaturated fatty acid- alkanolamine (PUFA-AA) derivatives as anti-inflammatory agents targeting Nur77 Fang, Hua
105 C p.
 artikel
92 Synthesis and neuroprotective effects of novel chalcone-triazole hybrids Sooknual, Pichjira
105 C p.
 artikel
93 Synthesis, anticancer and antioxidant properties of new indole and pyranoindole derivatives Iacopetta, Domenico
105 C p.
 artikel
94 Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors Kode, Jyoti
105 C p.
 artikel
95 Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids Nural, Yahya
105 C p.
 artikel
96 Synthesis of novel halogenated triarylpyrazoles as selective COX-2 inhibitors: Anti-inflammatory activity, histopatholgical profile and in-silico studies Abdellatif, Khaled R.A.
105 C p.
 artikel
97 Synthesis of some novel methyl β-orsellinate based 3, 5-disubstituted isoxazoles and their anti-proliferative activity: Identification of potent leads active against MCF-7 breast cancer cell Reddy, Srilakshmi Tirupathamma
105 C p.
 artikel
98 Synthesis of substituted N-(2′-nitrophenyl)pyrrolidine-2-carboxamides towards the design of proline-rich antimicrobial peptide mimics to eliminate bacterial resistance to antibiotics Odusami, Jocelyn A.
105 C p.
 artikel
99 Synthesis of triphenylphosphonium dibenzothiophene S-oxide derivatives and their effect on cell cycle as photodeoxygenation-based cytotoxic agents Isor, Ankita
105 C p.
 artikel
100 Synthetic and medicinal chemistry of phthalazines: Recent developments, opportunities and challenges Zaib, Sumera
105 C p.
 artikel
101 Targeted degradation of CD147 proteins in melanoma Zhou, Zhe
105 C p.
 artikel
102 Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase Fouda, Ahmed M.
105 C p.
 artikel
103 Titanium decorated iron oxide (Ti@Fe2O3) regulates the proliferation of bovine muscle satellite cells through oxidative stress Ramalingam, Vaikundamoorthy
105 C p.
 artikel
104 Toonaolides A–X, limonoids from Toona ciliata: Isolation, structural elucidation, and bioactivity against NLRP3 inflammasome Shi, Qiang-Qiang
105 C p.
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                             104 gevonden resultaten
 
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