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                             131 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Activity and specificity studies of the new thermostable esterase EstDZ2 Myrtollari, Kamela
104 C p.
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2 Agallolides A-M, including two rearranged ent-atisanes featuring a bicyclo[3.2.1]octane motif, from the Chinese Excoecaria agallocha Jiang, Zhong-Ping
104 C p.
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3 Aminotriazines with indole motif as novel, 5-HT7 receptor ligands with atypical binding mode Kułaga, Damian
104 C p.
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4 (+)- and (–)-Corydecumbenines A and B, two pairs of novel quaternary protoberberine alkaloid cycloadduct enantiomers with anti-neuroinflammatory and neuroprotective activities from the rhizomes of Corydalis decumbens Yin, Xu
104 C p.
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5 Anticandidal formyl phloroglucinol meroterpenoids: Biomimetic synthesis and in vitro evaluation Zhong, Lin–Fang
104 C p.
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6 Antidiabetic and cytotoxic polyhydroxylated oleanane and ursane type triterpenoids from Salvia grossheimii Zare, Somayeh
104 C p.
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7 Anti-inflammatory and antioxidant properties of chemical constituents of Broussonetia papyrifera Malaník, Milan
104 C p.
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8 Antimicrobial chloro-hydroxylactones derived from the biotransformation of bicyclic halolactones by cultures of Pleurotus ostreatus Grabarczyk, Małgorzata
104 C p.
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9 Antimycobacterial activity of azepanobetulin and its derivative: In vitro, in vivo, ADMET and docking studies Kazakova, Oxana
104 C p.
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10 Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta Zheng, Xiaofeng
104 C p.
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11 Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis El-Azab, Adel S.
104 C p.
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12 A perspective on potential target proteins of COVID-19: Comparison with SARS-CoV for designing new small molecules Kumar, Devendra
104 C p.
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13 A review on kinases phosphorylating the carboxyl-terminal domain of RNA polymerase II—Biological functions and inhibitors Zhang, Jianru
104 C p.
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14 A trifunctional Pt(II) complex alleviates the NHEJ/HR-related DSBs repairs to evade cisplatin-resistance in NSCLC Wang, Xing
104 C p.
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15 Bioactive sesquiterpene coumarins from the resin of Ferula sinkiangensis targeted on over-activation of microglia Guo, Tingting
104 C p.
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16 Bioassay-guided isolation of cyclooxygenase-2 inhibitory and antioxidant phenylpropanoid derivatives from the roots of Dendropanax dentiger Yang, Li
104 C p.
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17 Cadinane- and drimane-type sesquiterpenoids produced by Paecilomyces sp. TE-540, an endophyte from Nicotiana tabacum L., are acetylcholinesterase inhibitors Xu, Kuo
104 C p.
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18 Characterization of a novel thermostable glucose-tolerant GH1 β-glucosidase from the hyperthermophile Ignisphaera aggregans and its application in the efficient production of baohuoside I from icariin and total epimedium flavonoids Xie, Jingcong
104 C p.
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19 Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues Tsai, Shuo-En
104 C p.
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20 Combination of DN604 with gemcitabine led to cell apoptosis and cell motility inhibition via p38 MAPK signaling pathway in NSCLC Wang, Xinyi
104 C p.
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21 Copper (II)-based halogen-substituted chromone antitumor drug entities: Studying biomolecular interactions with ct-DNA mediated by sigma hole formation and cytotoxicity activity Arjmand, Farukh
104 C p.
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22 Core modified 8–17 DNAzymes with 2′-deoxy-2′-C-methylpyrimidine nucleosides Dellafiore, María
104 C p.
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23 Correlation study on methoxylation pattern of flavonoids and their heme-targeted antiplasmodial activity Ortiz, Sergio
104 C p.
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24 Corrigendum to “Hyperpatulols A-I, spirocyclic acylphloroglucinol derivatives with anti-migration activities from the flowers of hypericum patulum” [Bioorg. Chem. 87 (2019) 409–416] Liu, Yang-Yang
104 C p.
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25 Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking Konidala, Sathish Kumar
104 C p.
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26 Cytochalasins from an endophytic fungus Phoma multirostrata XJ-2-1 with cell cycle arrest and TRAIL-resistance-overcoming activities Peng, Xiaogang
104 C p.
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27 Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors Al-Wahaibi, Lamya H.
104 C p.
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28 Design and synthesis of novel 4-thiazolidinone derivatives with promising anti-breast cancer activity: Synthesis, characterization, in vitro and in vivo results Tahmasvand, Raheleh
104 C p.
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29 Design and synthesis of quinoxaline-1,3,4-oxadiazole hybrid derivatives as potent inhibitors of the anti-apoptotic Bcl-2 protein Ono, Yukari
104 C p.
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30 Design and synthesis of some barbituric and 1,3-dimethylbarbituric acid derivatives: A non-classical scaffold for potential PARP1 inhibitors Eldin A. Osman, Essam
104 C p.
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31 Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers Abbass, Eslam M.
104 C p.
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32 Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors Saleh, Nashwa M.
104 C p.
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33 Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors Wang, Guangcheng
104 C p.
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34 Design, synthesis and antitumor evaluation of novel 5-methylpyrazolo[1,5-a]pyrimidine derivatives as potential c-Met inhibitors Luo, Guolin
104 C p.
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35 Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents El-Zahabi, Mohamed Ayman
104 C p.
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36 Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents Hao, Shuang
104 C p.
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37 Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition Li, Na
104 C p.
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38 Design, synthesis and biological evaluation of thieno[3,2-d]pyrimidine derivatives containing aroyl hydrazone or aryl hydrazide moieties for PI3K and mTOR dual inhibition Han, Yufei
104 C p.
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39 Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles Wang, Chao
104 C p.
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40 Design, synthesis and evaluation of diaryl γ-dihydropyrone derivatives as cyclocurcumin mimetics and inhibitors of the aggregation of amyloid β Hotsumi, Mayumi
104 C p.
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41 Design, synthesis, and pharmacological evaluation of novel 1,2,4-triazol-3-amine derivatives as potential agonists of GABAA subtype receptors with anticonvulsant and hypnotic effects Jahani, Reza
104 C p.
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42 Design, synthesis and structure-activity relationship studies of novel partial FXR agonists for the treatment of fatty liver Qiu, Qianqian
104 C p.
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43 Design, synthesis and the structure-activity relationship of agonists targeting on the ALDH2 catalytic tunnel Cheng, Ming-Che
104 C p.
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44 Design, synthesis, antimicrobial activity and molecular docking studies of some novel di-substituted sulfonylquinoxaline derivatives Ammar, Yousry A.
104 C p.
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45 Development of activity-based probes for the protein deacylase Sirt1 Goetz, Christopher J.
104 C p.
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46 Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis Abdullah, Maryam Aisyah
104 C p.
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47 β,γ-Diaryl α-methylene-γ-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus Hamann, Henry J.
104 C p.
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48 Dimethylated acylphloroglucinol meroterpenoids with anti-oral-bacterial and anti-inflammatory activities from Hypericum elodeoides Li, Qi-Ji
104 C p.
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49 Discovery and rational design of 2-aminopyrimidine-based derivatives targeting Janus kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3) Li, Yingxiu
104 C p.
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50 Discovery, biological evaluation and docking studies of novel N-acyl-2-aminothiazoles fused (+)-nootkatone from Citrus paradisi Macf. as potential α-glucosidase inhibitors Guo, Yong
104 C p.
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51 Discovery of a cobalt (III) salen complex that induces apoptosis in Burkitt like lymphoma and leukemia cells, overcoming multidrug resistance in vitro Hopff, Sina M.
104 C p.
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52 Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency Buravchenko, Galina I.
104 C p.
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53 Discovery of dihydro-β-agarofurans from Tripterygium wilfordii with their H2O2-induced SH-SY5Y cell protective effects Zhou, Le
104 C p.
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54 Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities An, Ran
104 C p.
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55 Discovery of novel indazole-acylsulfonamide hybrids as selective Mcl-1 inhibitors Wan, Yichao
104 C p.
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56 Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors Abdel-Halim, Mohammad
104 C p.
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57 DNA binding studies of novel diazatruxenones analogs as potential anticancer agents: Synthesis, antitumor investigation, DNA binding, SAR and molecular modeling calculation El Sayed, Mardia T.
104 C p.
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58 Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19 Faheem,
104 C p.
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59 Drug-like biimidazole derivatives dually target c-MYC/BCL-2 G-quadruplexes and inhibit acute myeloid leukemia Hu, Ming-Hao
104 C p.
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60 Editorial Board
104 C p.
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61 Enantiomeric chromene derivatives with anticancer effects from Mallotus apelta Kiem, Phan Van
104 C p.
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62 Enantiomeric 8-O-4′-type neolignans from Crataegus pinnatifida exhibit cytotoxic effect via apoptosis and autophagy in Hep3B cells Shang, Xin-Yue
104 C p.
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63 Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) Zhang, Shengnan
104 C p.
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64 Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents Anbar, Hanan S.
104 C p.
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65 Exploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups Sharma, Anamika
104 C p.
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66 Fluorescently-labelled amyloid paired helical filaments (PHF) in monitoring its fibrillation kinetics Šmidlehner, Tamara
104 C p.
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67 Fungal mediated biotransformation of melengestrol acetate, and T-cell proliferation inhibitory activity of biotransformed compounds Javed, Saira
104 C p.
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68 68Ga-Labeled bismacrocyclic methylene phosphonate as potential bone seeking PET radiopharmaceutical Chauhan, Kanchan
104 C p.
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69 Geissoschizoline, a promising alkaloid for Alzheimer’s disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking Lima, Josélia A.
104 C p.
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70 Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes Su, Hai-Guo
104 C p.
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71 History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action Shafiei, Mohammad
104 C p.
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72 Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region Floresta, Giuseppe
104 C p.
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73 Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one Xu, Bin
104 C p.
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74 In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound Chan, Sock Ying
104 C p.
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75 Is oseltamivir suitable for fighting against COVID-19: In silico assessment, in vitro and retrospective study Tan, Qi
104 C p.
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76 Issue TOC
104 C p.
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77 Metabolites with phytopathogenic fungi inhibitory activities from the mangrove endophytic fungus Botryosphaeria ramose Hu, Zhibo
104 C p.
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78 Natural iridoids from Patrinia heterophylla showing anti-inflammatory activities in vitro and in vivo Wu, Peng
104 C p.
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79 New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their α-glucosidase inhibitory activity Wu, Meng-Jun
104 C p.
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80 New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential Shirinzadeh, Hanif
104 C p.
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81 New insight of red seaweed derived Callophycin A as an alternative strategy to treat drug resistance vaginal candidiasis Ganeshkumar, Arumugam
104 C p.
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82 New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study Li, Sin-Min
104 C p.
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83 New synthetic analogues of natural 5Z,9Z-dienoic acids: Stereoselective synthesis and study of the anticancer activity Makarov, Alexey A.
104 C p.
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84 Nonpeptidal compounds from the insect Polyphaga plancyi and their biological evaluation Zhu, Hong-Jie
104 C p.
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85 Novel adamantyl retinoid-related molecules with POLA1 inhibitory activity Cincinelli, Raffaella
104 C p.
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86 Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity Omar, Mohamed A.
104 C p.
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87 Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy Rodríguez-Enríquez, Fernanda
104 C p.
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88 Novel cyclic thiourea derivatives of aminoalcohols at the presence of AlCl3 catalyst as potent α-glycosidase and α-amylase inhibitors: Synthesis, characterization, bioactivity investigation and molecular docking studies Sujayev, Afsun
104 C p.
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89 Novel enantiopure isoxazolidine and C-alkyl imine oxide derivatives as potential hypoglycemic agents: Design, synthesis, dual inhibitors of α-amylase and α-glucosidase, ADMET and molecular docking study Ghannay, Siwar
104 C p.
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90 Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation Bułakowska, Anita
104 C p.
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91 Novel oligomeric neolignans with PTP1B inhibitory activity from the bark of Magnolia officinalis var. biloba Li, Chuan
104 C p.
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92 Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study Labib, Madlen B.
104 C p.
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93 Pehuén (Araucaria araucana) seed residues are a valuable source of natural antioxidants with nutraceutical, chemoprotective and metal corrosion-inhibiting properties Gallia, María C.
104 C p.
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94 Potent α-amylase inhibitors and radical (DPPH and ABTS) scavengers based on benzofuran-2-yl(phenyl)methanone derivatives: Syntheses, in vitro, kinetics, and in silico studies Ali, Irfan
104 C p.
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95 Prenylated xanthones and benzophenones from the fruits of Garcinia bracteata and their potential antiproliferative and anti-inflammatory activities Xue, Qing
104 C p.
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96 Preparation and assessment of a new radiotracer technetium-99m-6-hydrazinonicotinic acid-tyrosine as a targeting agent in tumor detecting through single photon emission tomography Mogadam, Hemat Yaghoubi
104 C p.
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97 P2X7 receptor inhibition by 2-amino-3-aryl-1,4-naphthoquinones de Luna Martins, Daniela
104 C p.
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98 (2R)- and (2S)- 2-hydroxy- hexanoyl and octanoyl-l-homoserine lactones: New highly potent Quorum Sensing modulators with opposite activities Zhang, Qiang
104 C p.
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99 Recent advancements in the medicinal chemistry of bacterial type II topoisomerase inhibitors Jaswal, Shalini
104 C p.
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100 Reductive domino reaction to access chromeno[2,3-c]isoquinoline-5-amines with antiproliferative activities against human tumor cells Yue, Xiaoyi
104 C p.
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101 Role of heterocyclic compounds in SARS and SARS CoV-2 pandemic Negi, Meenakshi
104 C p.
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102 Sesquiterpenoids, phenolic and lignan glycosides from the roots and rhizomes of Clematis hexapetala Pall. and their bioactivities Cai, Lu
104 C p.
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103 Some thiocarbamoyl based novel anticathepsin agents Kaur, Ravinder
104 C p.
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104 Structure-activity relationship studies of prostate-specific membrane antigen (PSMA) inhibitors derived from α-amino acid with (S)- or (R)-configuration at P1′ region Kwon, Hongmok
104 C p.
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105 Structure based drug discovery and in vitro activity testing for DNA gyrase inhibitors of Salmonella enterica serovar Typhi Sharma, Priyanka
104 C p.
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106 Study on enhanced serum protein protecting and anti-cathepsin activities of various curcumin formulations containing traditional excipients and bio-enhancers Raghav, Neera
104 C p.
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107 Syntheses and evaluation of daphnetin derivatives as novel G protein-coupled receptor inhibitors and activators Wang, Yinan
104 C p.
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108 Synthesis, ADMET prediction and reverse screening study of 3,4,5-trimethoxy phenyl ring pendant sulfur‐containing cyanopyrimidine derivatives as promising apoptosis inducing anticancer agents Nainwal, Lalit Mohan
104 C p.
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109 Synthesis and biological evaluation of 3-amino-1,2,4-triazole derivatives as potential anticancer compounds Grytsai, Oleksandr
104 C p.
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110 Synthesis and biological evaluation of β-ionone oriented proapoptosis agents by enhancing the ROS generation Yang, Jie
104 C p.
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111 Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors Thacker, Pavitra S.
104 C p.
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112 Synthesis and biological evaluation of substituted phenyl azetidine-2-one sulphonyl derivatives as potential antimicrobial and antiviral agents Mandal, Milan Kumar
104 C p.
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113 Synthesis and biological study of class I selective HDAC inhibitors with NO releasing activity Ding, Qin'ge
104 C p.
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114 Synthesis, biological evaluation and computational studies of acrylohydrazide derivatives as potential Staphylococcus aureus NorA efflux pump inhibitors Kumar, Gautam
104 C p.
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115 Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity Haffez, Hesham
104 C p.
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116 Synthesis, DNA/RNA-interaction and biological activity of benzo[k,l]xanthene lignans Tumir, Lidija-Marija
104 C p.
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117 Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives Munir, Abida
104 C p.
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118 Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones Sevinçli, Zekiye Şeyma
104 C p.
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119 Synthesis of new riboflavin modified ODNs: Effect of riboflavin moiety on the G-quadruplex arrangement and stability Romanucci, Valeria
104 C p.
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120 Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties Akin Kazancioglu, Elif
104 C p.
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121 Synthesis of [1,2,4]triazolo[4,3-a]quinoxaline-1,3,4-oxadiazole derivatives as potent antiproliferative agents via a hybrid pharmacophore approach Kaneko, Daiki
104 C p.
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122 Synthesis, physicochemical properties and biological activities of novel alkylphosphocholines with foscarnet moiety Timko, Lukáš
104 C p.
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123 Synthetic strategies in construction of organic low molecular-weight carrier-drug conjugates Skwarecki, Andrzej S.
104 C p.
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124 Targeted isolation of cytotoxic germacranolide sesquiterpenes from Elephantopus scaber L. using small molecule accurate recognition technology Bai, Ming
104 C p.
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125 Targeting EGFR tyrosine kinase: Synthesis, in vitro antitumor evaluation, and molecular modeling studies of benzothiazole-based derivatives Mokhtar, Amal M.
104 C p.
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126 Targeting pathogenic fungi, bacteria and fungal-bacterial biofilms by newly synthesized quaternary ammonium derivative of pyridoxine and terbinafine with dual action profile Garipov, Marsel R.
104 C p.
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127 TCF3-activated FAM201A enhances cell proliferation and invasion via miR-186-5p/TNKS1BP1 axis in triple-negative breast cancer Jia, Hongyao
104 C p.
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128 The oxygenated products of cryptotanshinone by biotransformation with Cunninghamella elegans exerting anti-neuroinflammatory effects by inhibiting TLR 4-mediated MAPK signaling pathway Wu, Jing-Shuai
104 C p.
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129 Two resveratrol analogs, pinosylvin and 4,4′-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway Wang, Cheng-niu
104 C p.
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130 Uncommon terpenoids with anti-inflammatory activity from the Hainan soft coral Sinularia tumulosa Cai, You-Sheng
104 C p.
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131 Unusual terpenoids from the fruits of Evodia rutaecarpa and their activation on the farnesoid X receptor Zhang, Ming
104 C p.
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                             131 gevonden resultaten
 
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