Digital Library
Close Browse articles from a journal
     Journal description
       All volumes of the corresponding journal
         All issues of the corresponding volume
                                       All articles of the corresponding issues
 
                             131 results found
no title author magazine year volume issue page(s) type
1 Activity and specificity studies of the new thermostable esterase EstDZ2 Myrtollari, Kamela

104 C p.
article
2 Agallolides A-M, including two rearranged ent-atisanes featuring a bicyclo[3.2.1]octane motif, from the Chinese Excoecaria agallocha Jiang, Zhong-Ping

104 C p.
article
3 Aminotriazines with indole motif as novel, 5-HT7 receptor ligands with atypical binding mode Kułaga, Damian

104 C p.
article
4 (+)- and (–)-Corydecumbenines A and B, two pairs of novel quaternary protoberberine alkaloid cycloadduct enantiomers with anti-neuroinflammatory and neuroprotective activities from the rhizomes of Corydalis decumbens Yin, Xu

104 C p.
article
5 Anticandidal formyl phloroglucinol meroterpenoids: Biomimetic synthesis and in vitro evaluation Zhong, Lin–Fang

104 C p.
article
6 Antidiabetic and cytotoxic polyhydroxylated oleanane and ursane type triterpenoids from Salvia grossheimii Zare, Somayeh

104 C p.
article
7 Anti-inflammatory and antioxidant properties of chemical constituents of Broussonetia papyrifera Malaník, Milan

104 C p.
article
8 Antimicrobial chloro-hydroxylactones derived from the biotransformation of bicyclic halolactones by cultures of Pleurotus ostreatus Grabarczyk, Małgorzata

104 C p.
article
9 Antimycobacterial activity of azepanobetulin and its derivative: In vitro, in vivo, ADMET and docking studies Kazakova, Oxana

104 C p.
article
10 Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta Zheng, Xiaofeng

104 C p.
article
11 Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis El-Azab, Adel S.

104 C p.
article
12 A perspective on potential target proteins of COVID-19: Comparison with SARS-CoV for designing new small molecules Kumar, Devendra

104 C p.
article
13 A review on kinases phosphorylating the carboxyl-terminal domain of RNA polymerase II—Biological functions and inhibitors Zhang, Jianru

104 C p.
article
14 A trifunctional Pt(II) complex alleviates the NHEJ/HR-related DSBs repairs to evade cisplatin-resistance in NSCLC Wang, Xing

104 C p.
article
15 Bioactive sesquiterpene coumarins from the resin of Ferula sinkiangensis targeted on over-activation of microglia Guo, Tingting

104 C p.
article
16 Bioassay-guided isolation of cyclooxygenase-2 inhibitory and antioxidant phenylpropanoid derivatives from the roots of Dendropanax dentiger Yang, Li

104 C p.
article
17 Cadinane- and drimane-type sesquiterpenoids produced by Paecilomyces sp. TE-540, an endophyte from Nicotiana tabacum L., are acetylcholinesterase inhibitors Xu, Kuo

104 C p.
article
18 Characterization of a novel thermostable glucose-tolerant GH1 β-glucosidase from the hyperthermophile Ignisphaera aggregans and its application in the efficient production of baohuoside I from icariin and total epimedium flavonoids Xie, Jingcong

104 C p.
article
19 Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues Tsai, Shuo-En

104 C p.
article
20 Combination of DN604 with gemcitabine led to cell apoptosis and cell motility inhibition via p38 MAPK signaling pathway in NSCLC Wang, Xinyi

104 C p.
article
21 Copper (II)-based halogen-substituted chromone antitumor drug entities: Studying biomolecular interactions with ct-DNA mediated by sigma hole formation and cytotoxicity activity Arjmand, Farukh

104 C p.
article
22 Core modified 8–17 DNAzymes with 2′-deoxy-2′-C-methylpyrimidine nucleosides Dellafiore, María

104 C p.
article
23 Correlation study on methoxylation pattern of flavonoids and their heme-targeted antiplasmodial activity Ortiz, Sergio

104 C p.
article
24 Corrigendum to “Hyperpatulols A-I, spirocyclic acylphloroglucinol derivatives with anti-migration activities from the flowers of hypericum patulum” [Bioorg. Chem. 87 (2019) 409–416] Liu, Yang-Yang

104 C p.
article
25 Coumarin-chalcone hybrids targeting insulin receptor: Design, synthesis, anti-diabetic activity, and molecular docking Konidala, Sathish Kumar

104 C p.
article
26 Cytochalasins from an endophytic fungus Phoma multirostrata XJ-2-1 with cell cycle arrest and TRAIL-resistance-overcoming activities Peng, Xiaogang

104 C p.
article
27 Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors Al-Wahaibi, Lamya H.

104 C p.
article
28 Design and synthesis of novel 4-thiazolidinone derivatives with promising anti-breast cancer activity: Synthesis, characterization, in vitro and in vivo results Tahmasvand, Raheleh

104 C p.
article
29 Design and synthesis of quinoxaline-1,3,4-oxadiazole hybrid derivatives as potent inhibitors of the anti-apoptotic Bcl-2 protein Ono, Yukari

104 C p.
article
30 Design and synthesis of some barbituric and 1,3-dimethylbarbituric acid derivatives: A non-classical scaffold for potential PARP1 inhibitors Eldin A. Osman, Essam

104 C p.
article
31 Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers Abbass, Eslam M.

104 C p.
article
32 Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors Saleh, Nashwa M.

104 C p.
article
33 Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors Wang, Guangcheng

104 C p.
article
34 Design, synthesis and antitumor evaluation of novel 5-methylpyrazolo[1,5-a]pyrimidine derivatives as potential c-Met inhibitors Luo, Guolin

104 C p.
article
35 Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents El-Zahabi, Mohamed Ayman

104 C p.
article
36 Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents Hao, Shuang

104 C p.
article
37 Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition Li, Na

104 C p.
article
38 Design, synthesis and biological evaluation of thieno[3,2-d]pyrimidine derivatives containing aroyl hydrazone or aryl hydrazide moieties for PI3K and mTOR dual inhibition Han, Yufei

104 C p.
article
39 Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles Wang, Chao

104 C p.
article
40 Design, synthesis and evaluation of diaryl γ-dihydropyrone derivatives as cyclocurcumin mimetics and inhibitors of the aggregation of amyloid β Hotsumi, Mayumi

104 C p.
article
41 Design, synthesis, and pharmacological evaluation of novel 1,2,4-triazol-3-amine derivatives as potential agonists of GABAA subtype receptors with anticonvulsant and hypnotic effects Jahani, Reza

104 C p.
article
42 Design, synthesis and structure-activity relationship studies of novel partial FXR agonists for the treatment of fatty liver Qiu, Qianqian

104 C p.
article
43 Design, synthesis and the structure-activity relationship of agonists targeting on the ALDH2 catalytic tunnel Cheng, Ming-Che

104 C p.
article
44 Design, synthesis, antimicrobial activity and molecular docking studies of some novel di-substituted sulfonylquinoxaline derivatives Ammar, Yousry A.

104 C p.
article
45 Development of activity-based probes for the protein deacylase Sirt1 Goetz, Christopher J.

104 C p.
article
46 Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis Abdullah, Maryam Aisyah

104 C p.
article
47 β,γ-Diaryl α-methylene-γ-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus Hamann, Henry J.

104 C p.
article
48 Dimethylated acylphloroglucinol meroterpenoids with anti-oral-bacterial and anti-inflammatory activities from Hypericum elodeoides Li, Qi-Ji

104 C p.
article
49 Discovery and rational design of 2-aminopyrimidine-based derivatives targeting Janus kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3) Li, Yingxiu

104 C p.
article
50 Discovery, biological evaluation and docking studies of novel N-acyl-2-aminothiazoles fused (+)-nootkatone from Citrus paradisi Macf. as potential α-glucosidase inhibitors Guo, Yong

104 C p.
article
51 Discovery of a cobalt (III) salen complex that induces apoptosis in Burkitt like lymphoma and leukemia cells, overcoming multidrug resistance in vitro Hopff, Sina M.

104 C p.
article
52 Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency Buravchenko, Galina I.

104 C p.
article
53 Discovery of dihydro-β-agarofurans from Tripterygium wilfordii with their H2O2-induced SH-SY5Y cell protective effects Zhou, Le

104 C p.
article
54 Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities An, Ran

104 C p.
article
55 Discovery of novel indazole-acylsulfonamide hybrids as selective Mcl-1 inhibitors Wan, Yichao

104 C p.
article
56 Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors Abdel-Halim, Mohammad

104 C p.
article
57 DNA binding studies of novel diazatruxenones analogs as potential anticancer agents: Synthesis, antitumor investigation, DNA binding, SAR and molecular modeling calculation El Sayed, Mardia T.

104 C p.
article
58 Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19 Faheem,

104 C p.
article
59 Drug-like biimidazole derivatives dually target c-MYC/BCL-2 G-quadruplexes and inhibit acute myeloid leukemia Hu, Ming-Hao

104 C p.
article
60 Editorial Board
104 C p.
article
61 Enantiomeric chromene derivatives with anticancer effects from Mallotus apelta Kiem, Phan Van

104 C p.
article
62 Enantiomeric 8-O-4′-type neolignans from Crataegus pinnatifida exhibit cytotoxic effect via apoptosis and autophagy in Hep3B cells Shang, Xin-Yue

104 C p.
article
63 Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) Zhang, Shengnan

104 C p.
article
64 Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents Anbar, Hanan S.

104 C p.
article
65 Exploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups Sharma, Anamika

104 C p.
article
66 Fluorescently-labelled amyloid paired helical filaments (PHF) in monitoring its fibrillation kinetics Šmidlehner, Tamara

104 C p.
article
67 Fungal mediated biotransformation of melengestrol acetate, and T-cell proliferation inhibitory activity of biotransformed compounds Javed, Saira

104 C p.
article
68 68Ga-Labeled bismacrocyclic methylene phosphonate as potential bone seeking PET radiopharmaceutical Chauhan, Kanchan

104 C p.
article
69 Geissoschizoline, a promising alkaloid for Alzheimer’s disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking Lima, Josélia A.

104 C p.
article
70 Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes Su, Hai-Guo

104 C p.
article
71 History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action Shafiei, Mohammad

104 C p.
article
72 Identification of a potent heme oxygenase-2 (HO-2) inhibitor by targeting the secondary hydrophobic pocket of the HO-2 western region Floresta, Giuseppe

104 C p.
article
73 Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one Xu, Bin

104 C p.
article
74 In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound Chan, Sock Ying

104 C p.
article
75 Is oseltamivir suitable for fighting against COVID-19: In silico assessment, in vitro and retrospective study Tan, Qi

104 C p.
article
76 Issue TOC
104 C p.
article
77 Metabolites with phytopathogenic fungi inhibitory activities from the mangrove endophytic fungus Botryosphaeria ramose Hu, Zhibo

104 C p.
article
78 Natural iridoids from Patrinia heterophylla showing anti-inflammatory activities in vitro and in vivo Wu, Peng

104 C p.
article
79 New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their α-glucosidase inhibitory activity Wu, Meng-Jun

104 C p.
article
80 New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential Shirinzadeh, Hanif

104 C p.
article
81 New insight of red seaweed derived Callophycin A as an alternative strategy to treat drug resistance vaginal candidiasis Ganeshkumar, Arumugam

104 C p.
article
82 New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study Li, Sin-Min

104 C p.
article
83 New synthetic analogues of natural 5Z,9Z-dienoic acids: Stereoselective synthesis and study of the anticancer activity Makarov, Alexey A.

104 C p.
article
84 Nonpeptidal compounds from the insect Polyphaga plancyi and their biological evaluation Zhu, Hong-Jie

104 C p.
article
85 Novel adamantyl retinoid-related molecules with POLA1 inhibitory activity Cincinelli, Raffaella

104 C p.
article
86 Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity Omar, Mohamed A.

104 C p.
article
87 Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy Rodríguez-Enríquez, Fernanda

104 C p.
article
88 Novel cyclic thiourea derivatives of aminoalcohols at the presence of AlCl3 catalyst as potent α-glycosidase and α-amylase inhibitors: Synthesis, characterization, bioactivity investigation and molecular docking studies Sujayev, Afsun

104 C p.
article
89 Novel enantiopure isoxazolidine and C-alkyl imine oxide derivatives as potential hypoglycemic agents: Design, synthesis, dual inhibitors of α-amylase and α-glucosidase, ADMET and molecular docking study Ghannay, Siwar

104 C p.
article
90 Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation Bułakowska, Anita

104 C p.
article
91 Novel oligomeric neolignans with PTP1B inhibitory activity from the bark of Magnolia officinalis var. biloba Li, Chuan

104 C p.
article
92 Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study Labib, Madlen B.

104 C p.
article
93 Pehuén (Araucaria araucana) seed residues are a valuable source of natural antioxidants with nutraceutical, chemoprotective and metal corrosion-inhibiting properties Gallia, María C.

104 C p.
article
94 Potent α-amylase inhibitors and radical (DPPH and ABTS) scavengers based on benzofuran-2-yl(phenyl)methanone derivatives: Syntheses, in vitro, kinetics, and in silico studies Ali, Irfan

104 C p.
article
95 Prenylated xanthones and benzophenones from the fruits of Garcinia bracteata and their potential antiproliferative and anti-inflammatory activities Xue, Qing

104 C p.
article
96 Preparation and assessment of a new radiotracer technetium-99m-6-hydrazinonicotinic acid-tyrosine as a targeting agent in tumor detecting through single photon emission tomography Mogadam, Hemat Yaghoubi

104 C p.
article
97 P2X7 receptor inhibition by 2-amino-3-aryl-1,4-naphthoquinones de Luna Martins, Daniela

104 C p.
article
98 (2R)- and (2S)- 2-hydroxy- hexanoyl and octanoyl-l-homoserine lactones: New highly potent Quorum Sensing modulators with opposite activities Zhang, Qiang

104 C p.
article
99 Recent advancements in the medicinal chemistry of bacterial type II topoisomerase inhibitors Jaswal, Shalini

104 C p.
article
100 Reductive domino reaction to access chromeno[2,3-c]isoquinoline-5-amines with antiproliferative activities against human tumor cells Yue, Xiaoyi

104 C p.
article
101 Role of heterocyclic compounds in SARS and SARS CoV-2 pandemic Negi, Meenakshi

104 C p.
article
102 Sesquiterpenoids, phenolic and lignan glycosides from the roots and rhizomes of Clematis hexapetala Pall. and their bioactivities Cai, Lu

104 C p.
article
103 Some thiocarbamoyl based novel anticathepsin agents Kaur, Ravinder

104 C p.
article
104 Structure-activity relationship studies of prostate-specific membrane antigen (PSMA) inhibitors derived from α-amino acid with (S)- or (R)-configuration at P1′ region Kwon, Hongmok

104 C p.
article
105 Structure based drug discovery and in vitro activity testing for DNA gyrase inhibitors of Salmonella enterica serovar Typhi Sharma, Priyanka

104 C p.
article
106 Study on enhanced serum protein protecting and anti-cathepsin activities of various curcumin formulations containing traditional excipients and bio-enhancers Raghav, Neera

104 C p.
article
107 Syntheses and evaluation of daphnetin derivatives as novel G protein-coupled receptor inhibitors and activators Wang, Yinan

104 C p.
article
108 Synthesis, ADMET prediction and reverse screening study of 3,4,5-trimethoxy phenyl ring pendant sulfur‐containing cyanopyrimidine derivatives as promising apoptosis inducing anticancer agents Nainwal, Lalit Mohan

104 C p.
article
109 Synthesis and biological evaluation of 3-amino-1,2,4-triazole derivatives as potential anticancer compounds Grytsai, Oleksandr

104 C p.
article
110 Synthesis and biological evaluation of β-ionone oriented proapoptosis agents by enhancing the ROS generation Yang, Jie

104 C p.
article
111 Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors Thacker, Pavitra S.

104 C p.
article
112 Synthesis and biological evaluation of substituted phenyl azetidine-2-one sulphonyl derivatives as potential antimicrobial and antiviral agents Mandal, Milan Kumar

104 C p.
article
113 Synthesis and biological study of class I selective HDAC inhibitors with NO releasing activity Ding, Qin'ge

104 C p.
article
114 Synthesis, biological evaluation and computational studies of acrylohydrazide derivatives as potential Staphylococcus aureus NorA efflux pump inhibitors Kumar, Gautam

104 C p.
article
115 Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity Haffez, Hesham

104 C p.
article
116 Synthesis, DNA/RNA-interaction and biological activity of benzo[k,l]xanthene lignans Tumir, Lidija-Marija

104 C p.
article
117 Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives Munir, Abida

104 C p.
article
118 Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones Sevinçli, Zekiye Şeyma

104 C p.
article
119 Synthesis of new riboflavin modified ODNs: Effect of riboflavin moiety on the G-quadruplex arrangement and stability Romanucci, Valeria

104 C p.
article
120 Synthesis of N-phenylsulfonamide derivatives and investigation of some esterase enzymes inhibiting properties Akin Kazancioglu, Elif

104 C p.
article
121 Synthesis of [1,2,4]triazolo[4,3-a]quinoxaline-1,3,4-oxadiazole derivatives as potent antiproliferative agents via a hybrid pharmacophore approach Kaneko, Daiki

104 C p.
article
122 Synthesis, physicochemical properties and biological activities of novel alkylphosphocholines with foscarnet moiety Timko, Lukáš

104 C p.
article
123 Synthetic strategies in construction of organic low molecular-weight carrier-drug conjugates Skwarecki, Andrzej S.

104 C p.
article
124 Targeted isolation of cytotoxic germacranolide sesquiterpenes from Elephantopus scaber L. using small molecule accurate recognition technology Bai, Ming

104 C p.
article
125 Targeting EGFR tyrosine kinase: Synthesis, in vitro antitumor evaluation, and molecular modeling studies of benzothiazole-based derivatives Mokhtar, Amal M.

104 C p.
article
126 Targeting pathogenic fungi, bacteria and fungal-bacterial biofilms by newly synthesized quaternary ammonium derivative of pyridoxine and terbinafine with dual action profile Garipov, Marsel R.

104 C p.
article
127 TCF3-activated FAM201A enhances cell proliferation and invasion via miR-186-5p/TNKS1BP1 axis in triple-negative breast cancer Jia, Hongyao

104 C p.
article
128 The oxygenated products of cryptotanshinone by biotransformation with Cunninghamella elegans exerting anti-neuroinflammatory effects by inhibiting TLR 4-mediated MAPK signaling pathway Wu, Jing-Shuai

104 C p.
article
129 Two resveratrol analogs, pinosylvin and 4,4′-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway Wang, Cheng-niu

104 C p.
article
130 Uncommon terpenoids with anti-inflammatory activity from the Hainan soft coral Sinularia tumulosa Cai, You-Sheng

104 C p.
article
131 Unusual terpenoids from the fruits of Evodia rutaecarpa and their activation on the farnesoid X receptor Zhang, Ming

104 C p.
article
                             131 results found
 
 Koninklijke Bibliotheek - National Library of the Netherlands