nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A chemistry wiki to facilitate and enhance compound design in drug discovery
|
Robb, Graeme R. |
|
2013 |
|
3-4 |
p. 141-147 7 p. |
artikel |
2 |
Adiponectin normalization: a clue to the anti-metabolic syndrome action of rimonabant
|
Maynadier, Marie |
|
2009 |
|
3-4 |
p. 192-197 6 p. |
artikel |
3 |
A guidance for renal biomarker lead optimization and use in translational pharmacodynamics
|
Ozer, Josef S. |
|
2010 |
|
3-4 |
p. 142-147 6 p. |
artikel |
4 |
Being a Scientist today: are you still having fun?
|
Anastasia, Luigi |
|
2013 |
|
3-4 |
p. 107-109 3 p. |
artikel |
5 |
Biologics: a new approach needed?
|
Foster, Keith A. |
|
2010 |
|
3-4 |
p. 81-83 3 p. |
artikel |
6 |
Biomarkers of Parkinson's disease: current status and future perspectives
|
Wang, Jian |
|
2013 |
|
3-4 |
p. 155-162 8 p. |
artikel |
7 |
Biomimetic tissues on a chip for drug discovery
|
Ghaemmaghami, Amir M. |
|
2012 |
|
3-4 |
p. 173-181 9 p. |
artikel |
8 |
Biotechnology in Ireland: hard work, money and the brain gain
|
O’Neill, Michael F |
|
2007 |
|
3-4 |
p. 108-111 4 p. |
artikel |
9 |
Can molecular biomarker-based patient selection in Phase I trials accelerate anticancer drug development?
|
Carden, Craig P. |
|
2010 |
|
3-4 |
p. 88-97 10 p. |
artikel |
10 |
Chemical probes for biological systems
|
Garcia-Serna, Ricard |
|
2011 |
|
3-4 |
p. 99-106 8 p. |
artikel |
11 |
Chromatin-modulating agents as epigenetic anticancer drugs – ‘the die is cast’
|
Konstantinopoulos, Panagiotis A. |
|
2006 |
|
3-4 |
p. 91-93 3 p. |
artikel |
12 |
Circulating tumour-derived predictive biomarkers in oncology
|
Hodgson, Darren R. |
|
2010 |
|
3-4 |
p. 98-101 4 p. |
artikel |
13 |
Combinatorial chemistry improves molecular options over pre-existing leads
|
Edwards, Paul |
|
2007 |
|
3-4 |
p. 185-186 2 p. |
artikel |
14 |
Contents
|
|
|
2013 |
|
3-4 |
p. i- 1 p. |
artikel |
15 |
Contents
|
|
|
2013 |
|
3-4 |
p. iii- 1 p. |
artikel |
16 |
Contents
|
|
|
2012 |
|
3-4 |
p. i- 1 p. |
artikel |
17 |
Contents
|
|
|
2012 |
|
3-4 |
p. iii- 1 p. |
artikel |
18 |
Contents page 2
|
|
|
2009 |
|
3-4 |
p. iii- 1 p. |
artikel |
19 |
Contents page 1
|
|
|
2009 |
|
3-4 |
p. i- 1 p. |
artikel |
20 |
Contents page 2
|
|
|
2010 |
|
3-4 |
p. iii- 1 p. |
artikel |
21 |
Contents page 1
|
|
|
2010 |
|
3-4 |
p. i- 1 p. |
artikel |
22 |
Contents page 1
|
|
|
2008 |
|
3-4 |
p. i- 1 p. |
artikel |
23 |
Contents page 1
|
|
|
2011 |
|
3-4 |
p. i- 1 p. |
artikel |
24 |
Contents page 2
|
|
|
2011 |
|
3-4 |
p. iii- 1 p. |
artikel |
25 |
Current and future ophthalmic drug delivery systems
|
del Amo, Eva M. |
|
2008 |
|
3-4 |
p. 135-143 9 p. |
artikel |
26 |
Diary
|
|
|
2007 |
|
3-4 |
p. 187- 1 p. |
artikel |
27 |
Disease induction by human microbial pathogens in plant-model systems: potential, problems and prospects
|
van Baarlen, Peter |
|
2007 |
|
3-4 |
p. 167-173 7 p. |
artikel |
28 |
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
|
Whitworth, Alexander J. |
|
2006 |
|
3-4 |
p. 119-126 8 p. |
artikel |
29 |
Editorial Board
|
|
|
2008 |
|
3-4 |
p. iii- 1 p. |
artikel |
30 |
Effective pharmaceutical regulation needs alignment with doctors
|
Ebbers, Hans C. |
|
2012 |
|
3-4 |
p. 100-103 4 p. |
artikel |
31 |
Emergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterials
|
Mimeault, Murielle |
|
2013 |
|
3-4 |
p. 128-140 13 p. |
artikel |
32 |
Emerging chemical and biological approaches for the preparation of discovery libraries
|
Boldt, Grant E. |
|
2006 |
|
3-4 |
p. 143-148 6 p. |
artikel |
33 |
Erratum
|
|
|
2007 |
|
3-4 |
p. 182- 1 p. |
artikel |
34 |
Fetal hypoxia and programming of matrix metalloproteinases
|
Tong, Wenni |
|
2012 |
|
3-4 |
p. 124-134 11 p. |
artikel |
35 |
Filling the pipeline for neglected diseases: creation of a medicinal chemistry-centric international drug discovery institute [iDDi]
|
Kozikowski, Alan P. |
|
2008 |
|
3-4 |
p. 97-98 2 p. |
artikel |
36 |
Fragments, network biology and designing multiple ligands
|
Morphy, Richard |
|
2007 |
|
3-4 |
p. 156-160 5 p. |
artikel |
37 |
From biomarker strategies to biomarker activities and back
|
van Gool, Alain J. |
|
2010 |
|
3-4 |
p. 121-126 6 p. |
artikel |
38 |
Global clinical data interchange standards are here!
|
Souza, Tammy |
|
2007 |
|
3-4 |
p. 174-181 8 p. |
artikel |
39 |
Imaging in the cardiovascular and metabolic disease area
|
Comley, Robert A. |
|
2013 |
|
3-4 |
p. 185-192 8 p. |
artikel |
40 |
Iminosugars past, present and future: medicines for tomorrow
|
Horne, Graeme |
|
2011 |
|
3-4 |
p. 107-118 12 p. |
artikel |
41 |
Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits
|
Wunberg, Tobias |
|
2006 |
|
3-4 |
p. 175-180 6 p. |
artikel |
42 |
Informatic innovations in glycobiology: relevance to drug discovery
|
Mamitsuka, Hiroshi |
|
2008 |
|
3-4 |
p. 118-123 6 p. |
artikel |
43 |
In silico drug repositioning – what we need to know
|
Liu, Zhichao |
|
2013 |
|
3-4 |
p. 110-115 6 p. |
artikel |
44 |
In silico selection of active siRNA
|
Patzel, Volker |
|
2007 |
|
3-4 |
p. 139-148 10 p. |
artikel |
45 |
In vitro models for human skin disease
|
Semlin, Lydia |
|
2011 |
|
3-4 |
p. 132-139 8 p. |
artikel |
46 |
Isotopic biomarker discovery and application in translational medicine
|
Bayele, Henry K. |
|
2010 |
|
3-4 |
p. 127-136 10 p. |
artikel |
47 |
Keynote review: Chromatin control and cancer-drug discovery: realizing the promise
|
Inche, Adam G. |
|
2006 |
|
3-4 |
p. 97-109 13 p. |
artikel |
48 |
Lead optimization in the nondrug-like space
|
Zhao, Hongyu |
|
2011 |
|
3-4 |
p. 158-163 6 p. |
artikel |
49 |
Liposomal drug formulations in cancer therapy: 15 years along the road
|
Slingerland, Marije |
|
2012 |
|
3-4 |
p. 160-166 7 p. |
artikel |
50 |
Liquid chromatography–mass spectrometry in in vitro drug metabolite screening
|
Tolonen, Ari |
|
2009 |
|
3-4 |
p. 120-133 14 p. |
artikel |
51 |
Low-dose metronomic chemotherapy: from past experience to new paradigms in the treatment of cancer
|
Loven, David |
|
2013 |
|
3-4 |
p. 193-201 9 p. |
artikel |
52 |
Manipulating molecular architecture in parallel
|
Edwards, Paul |
|
2007 |
|
3-4 |
p. 183-184 2 p. |
artikel |
53 |
Mechanistic systems modeling to guide drug discovery and development
|
Schmidt, Brian J. |
|
2013 |
|
3-4 |
p. 116-127 12 p. |
artikel |
54 |
Medicines for tropical diseases; support through tax-incentives
|
John, Jacob E. |
|
2011 |
|
3-4 |
p. 91-92 2 p. |
artikel |
55 |
Mesopore-assisted profiling strategies in clinical proteomics for drug/target discovery
|
Savino, Rocco |
|
2012 |
|
3-4 |
p. 143-152 10 p. |
artikel |
56 |
Micro- and nanofluidic systems for high-throughput biological screening
|
Hong, Jongin |
|
2009 |
|
3-4 |
p. 134-146 13 p. |
artikel |
57 |
Modelling iterative compound optimisation using a self-avoiding walk
|
Delaney, John |
|
2009 |
|
3-4 |
p. 198-207 10 p. |
artikel |
58 |
Monitor – An antitumor dual inhibitor of cyclin-dependent kinases and Aurora kinases
|
Westwell, Andrew D. |
|
2006 |
|
3-4 |
p. 182- 1 p. |
artikel |
59 |
Monitor – A proapoptotic resveratrol analogue
|
Westwell, Andrew D. |
|
2006 |
|
3-4 |
p. 182-183 2 p. |
artikel |
60 |
Monitor – Combinatorial approach towards the discovery of tryptase inhibitors
|
Edwards, Paul |
|
2006 |
|
3-4 |
p. 181-182 2 p. |
artikel |
61 |
Monitor – Molecules
|
Edwards, Paul |
|
2006 |
|
3-4 |
p. 181- 1 p. |
artikel |
62 |
MRI as a tool for evaluation of oral controlled release dosage forms
|
Dorożyński, Przemysław P. |
|
2012 |
|
3-4 |
p. 110-123 14 p. |
artikel |
63 |
Nanotechnology in ocular drug delivery
|
Sahoo, Sanjeeb K. |
|
2008 |
|
3-4 |
p. 144-151 8 p. |
artikel |
64 |
Newly developed strategies for multifunctional mitochondria-targeted agents in cancer therapy
|
Zhang, Erlong |
|
2011 |
|
3-4 |
p. 140-146 7 p. |
artikel |
65 |
Oncology exploration: charting cancer medicinal chemistry space
|
Lloyd, David G. |
|
2006 |
|
3-4 |
p. 149-159 11 p. |
artikel |
66 |
Ophthalmic light sensitive nanocarrier systems
|
Christie, Jennifer G. |
|
2008 |
|
3-4 |
p. 124-134 11 p. |
artikel |
67 |
Optimizing the use of open-source software applications in drug discovery
|
Geldenhuys, Werner J. |
|
2006 |
|
3-4 |
p. 127-132 6 p. |
artikel |
68 |
Orphan drugs: the regulatory environment
|
Franco, Pedro |
|
2013 |
|
3-4 |
p. 163-172 10 p. |
artikel |
69 |
Outsourcing lead optimization: the eye of the storm
|
Clark, David E. |
|
2011 |
|
3-4 |
p. 147-157 11 p. |
artikel |
70 |
Peptides in DNA delivery: current insights and future directions
|
Mann, Anita |
|
2008 |
|
3-4 |
p. 152-160 9 p. |
artikel |
71 |
Perispinal etanercept for neuroinflammatory disorders
|
Tobinick, Edward |
|
2009 |
|
3-4 |
p. 168-177 10 p. |
artikel |
72 |
PET and SPECT tracers for glutamate receptors
|
Majo, Vattoly J. |
|
2013 |
|
3-4 |
p. 173-184 12 p. |
artikel |
73 |
Phenothiazine: the seven lives of pharmacology's first lead structure
|
Ohlow, Maike J. |
|
2011 |
|
3-4 |
p. 119-131 13 p. |
artikel |
74 |
Plant-derived compounds in clinical trials
|
Saklani, Arvind |
|
2008 |
|
3-4 |
p. 161-171 11 p. |
artikel |
75 |
Potential role of pharmacogenetics in anti-TNF treatment of rheumatoid arthritis and Crohn's disease
|
Kooloos, Wouter M. |
|
2007 |
|
3-4 |
p. 125-131 7 p. |
artikel |
76 |
Practical purification of hydrophilic fragments and lead/drug-like molecules by reverse phase flash chromatography: tips, tricks and contemporary developments
|
Hobbs, Andrew N. |
|
2013 |
|
3-4 |
p. 148-154 7 p. |
artikel |
77 |
Predicting druggable binding sites at the protein–protein interface
|
Fuller, Jonathan C. |
|
2009 |
|
3-4 |
p. 155-161 7 p. |
artikel |
78 |
Progress towards personalized medicine
|
Bates, Stewart |
|
2010 |
|
3-4 |
p. 115-120 6 p. |
artikel |
79 |
Project management of life-science research projects: project characteristics, challenges and training needs
|
Beukers, Margot W. |
|
2011 |
|
3-4 |
p. 93-98 6 p. |
artikel |
80 |
Rare disease patient groups as clinical researchers
|
Polich, Ginger R. |
|
2012 |
|
3-4 |
p. 167-172 6 p. |
artikel |
81 |
Rational drug design in parasitology: trans-sialidase as a case study for Chagas disease
|
Neres, João |
|
2008 |
|
3-4 |
p. 110-117 8 p. |
artikel |
82 |
Recent advances in molecular imaging biomarkers in cancer: application of bench to bedside technologies
|
van der Meel, Roy |
|
2010 |
|
3-4 |
p. 102-114 13 p. |
artikel |
83 |
Retrospective clinical analysis for drug rescue: for new indications or stratified patient groups
|
Cavalla, David |
|
2012 |
|
3-4 |
p. 104-109 6 p. |
artikel |
84 |
Role of pharmacologically active metabolites in drug discovery and development
|
Fura, Aberra |
|
2006 |
|
3-4 |
p. 133-142 10 p. |
artikel |
85 |
SAGE and related approaches for cancer target identification
|
Porter, Dale |
|
2006 |
|
3-4 |
p. 110-118 9 p. |
artikel |
86 |
Scaffold selection and scaffold hopping in lead generation: a medicinal chemistry perspective
|
Zhao, Hongyu |
|
2007 |
|
3-4 |
p. 149-155 7 p. |
artikel |
87 |
Seeing small molecules in action with bioorthogonal chemistry
|
Raghavan, Anuradha S. |
|
2009 |
|
3-4 |
p. 178-184 7 p. |
artikel |
88 |
Selective optimization of side activities: the SOSA approach
|
Wermuth, Camille G. |
|
2006 |
|
3-4 |
p. 160-164 5 p. |
artikel |
89 |
Something's got to give: psychiatric disease on the rise and novel drug development on the decline
|
Chandler, Daniel J. |
|
2013 |
|
3-4 |
p. 202-206 5 p. |
artikel |
90 |
Strategies and tactics for optimizing the Hit-to-Lead process and beyond—A computational chemistry perspective
|
Manly, Charles J. |
|
2008 |
|
3-4 |
p. 99-109 11 p. |
artikel |
91 |
Supporting and developing bioscience in Wales. Showcasing Welsh talent at BioWales 2009
|
Thomas, Sharon |
|
2009 |
|
3-4 |
p. 113-114 2 p. |
artikel |
92 |
Target discovery from data mining approaches
|
Yang, Yongliang |
|
2009 |
|
3-4 |
p. 147-154 8 p. |
artikel |
93 |
Targeted therapy for neuro-oncology: reviewing the menu
|
Lampson, Lois A. |
|
2009 |
|
3-4 |
p. 185-191 7 p. |
artikel |
94 |
Targeting mammalian target of rapamycin (mTOR) for health and diseases
|
Tsang, Chi Kwan |
|
2007 |
|
3-4 |
p. 112-124 13 p. |
artikel |
95 |
Targeting structural flexibility in HIV-1 protease inhibitor binding
|
Hornak, Viktor |
|
2007 |
|
3-4 |
p. 132-138 7 p. |
artikel |
96 |
Targeting tight junction proteins-significance for drug development
|
Kondoh, Masuo |
|
2008 |
|
3-4 |
p. 180-186 7 p. |
artikel |
97 |
Targeting virulence: A new paradigm for antifungals
|
Gauwerky, Katharina |
|
2009 |
|
3-4 |
p. 214-222 9 p. |
artikel |
98 |
The application of FAST-NMR for the identification of novel drug discovery targets
|
Powers, Robert |
|
2008 |
|
3-4 |
p. 172-179 8 p. |
artikel |
99 |
The formulation of polyhedral boranes for the boron neutron capture therapy of cancer
|
Calabrese, Gianpiero |
|
2012 |
|
3-4 |
p. 153-159 7 p. |
artikel |
100 |
The future of drug safety testing: expanding the view and narrowing the focus
|
Stevens, James L. |
|
2009 |
|
3-4 |
p. 162-167 6 p. |
artikel |
101 |
The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types
|
Ritchie, Timothy J. |
|
2011 |
|
3-4 |
p. 164-171 8 p. |
artikel |
102 |
The impact of microwave-assisted organic synthesis in drug discovery
|
Mavandadi, Farah |
|
2006 |
|
3-4 |
p. 165-174 10 p. |
artikel |
103 |
The importance of aryl C–Cl⋯π interaction in ligand–protein binding
|
Yeung, Kap-Sun |
|
2010 |
|
3-4 |
p. 158- 1 p. |
artikel |
104 |
The quest for biomarkers in tuberculosis
|
Parida, Shreemanta K. |
|
2010 |
|
3-4 |
p. 148-157 10 p. |
artikel |
105 |
Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity
|
Argilés, Josep M. |
|
2009 |
|
3-4 |
p. 208-213 6 p. |
artikel |
106 |
The rise of micropharma
|
Barden, Christopher J. |
|
2010 |
|
3-4 |
p. 84-87 4 p. |
artikel |
107 |
The routes to orphan drug designation – our recent experience at the FDA
|
Lev, Daniel |
|
2012 |
|
3-4 |
p. 97-99 3 p. |
artikel |
108 |
The use of technologies for the discovery of novel chemotherapeutic agents
|
Edwards, Paul |
|
2009 |
|
3-4 |
p. 223-225 3 p. |
artikel |
109 |
The value of in silico chemistry in the safety assessment of chemicals in the consumer goods and pharmaceutical industries
|
Modi, Sandeep |
|
2012 |
|
3-4 |
p. 135-142 8 p. |
artikel |
110 |
Treating desires not diseases: a pill for every ill and an ill for every pill?
|
Triggle, David. J. |
|
2007 |
|
3-4 |
p. 161-166 6 p. |
artikel |
111 |
Uppsala: turning knowledge into profits
|
Neil, Madeleine |
|
2006 |
|
3-4 |
p. 94-96 3 p. |
artikel |
112 |
Use of biomarkers in the discovery of novel anti-schizophrenia drugs
|
Mikkelsen, Jens D. |
|
2010 |
|
3-4 |
p. 137-141 5 p. |
artikel |
113 |
Where is the hope for drug discovery? Let history tell the future
|
Kong, De-Xin |
|
2009 |
|
3-4 |
p. 115-119 5 p. |
artikel |
114 |
Where is the optimism? Warrior teachings to regain the drug discovery spirit
|
Uitdehaag, Joost C.M. |
|
2007 |
|
3-4 |
p. 105-107 3 p. |
artikel |