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                             60 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A novel synthetic acanthoic acid analogues and their cytotoxic activity in cholangiocarcinoma cells Kasemsuk, Teerapich
29 C p.
 artikel
2 Anti-tumor effects and cell motility inhibition of the DN604-gemcitabine combined treatment in human bladder cancer models Wang, Xinyi
29 C p.
 artikel
3 Assessing the cellular toxicity of peptide inhibitors of intracellular protein-protein interactions by microinjection Babu Reddiar, Sanjeevini
29 C p.
 artikel
4 Biotin and glucose co-modified multi-targeting liposomes for efficient delivery of chemotherapeutics for the treatment of glioma Liu, Qijun
29 C p.
 artikel
5 Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding Shi, Genbin
29 C p.
 artikel
6 C-2 derivatized 8-sulfonamidoquinolines as antibacterial compounds Davison, Emma K.
29 C p.
 artikel
7 Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide Araie, Yuki
29 C p.
 artikel
8 Covalent peptides and proteins for therapeutics Berdan, Viktoriya Y.
29 C p.
 artikel
9 Design and development of FGF-23 antagonists: Definition of the pharmacophore and initial structure-activity relationships probed by synthetic analogues Downs, Ryan P.
29 C p.
 artikel
10 Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors El-Adl, Khaled
29 C p.
 artikel
11 Design, synthesis, and biological activity of novel semicarbazones as potent Ryanodine receptor1 inhibitors of Alzheimer’s disease Dai, Baozhu
29 C p.
 artikel
12 Design, synthesis and biological evaluation of imidazolopyridone derivatives as novel BRD4 inhibitors Yang, Yifei
29 C p.
 artikel
13 Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors Huo, Peng-Chao
29 C p.
 artikel
14 Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors Du, Lifei
29 C p.
 artikel
15 Design, synthesis and stepwise optimization of nitrile-based inhibitors of cathepsins B and L Cianni, Lorenzo
29 C p.
 artikel
16 Design, synthesis biological activity, and docking of novel fluopyram derivatives containing guanidine group Liang, Peibo
29 C p.
 artikel
17 Development of a novel acetyl glucose-modified gefitinib derivative to enhance the radiosensitizing effect Yamahana, Hirari
29 C p.
 artikel
18 Discovery of 4-amino-1H-pyrazolo[3,4-d]pyrimidin derivatives as novel discoidin domain receptor 1 (DDR1) inhibitors Dong, Ru
29 C p.
 artikel
19 Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors Hao, Guiyun
29 C p.
 artikel
20 Discovery of new thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives as orally active phosphoinositide 3-kinase inhibitors Sun, Yan
29 C p.
 artikel
21 Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3Kα inhibitors via docking-based virtual screening Gu, Dongyan
29 C p.
 artikel
22 Editorial Board
29 C p.
 artikel
23 Efficient synthesis and antitumor evaluation of 4-aminomethyl-N-arylpyrazoles: Discovery of potent and selective agents for ovarian cancer da Silva, Michael J.V.
29 C p.
 artikel
24 Ester modification at the 3′ end of anti-microRNA oligonucleotides increases potency of microRNA inhibition Pham, Kevin M.
29 C p.
 artikel
25 Evaluation of imidazo[2,1–b]thiazole-based anticancer agents in one decade (2011–2020): Current status and future prospects Sbenati, Rawan M.
29 C p.
 artikel
26 Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors Cantini, Niccolò
29 C p.
 artikel
27 18F-labeled 2-phenylbenzoheterocycles with chiral dihydroxyl side chains as β-amyloid imaging probes Li, Yuying
29 C p.
 artikel
28 Fluorescent molecular rotors as sensors for the detection of thymidine phosphorylase Petaccia, Manuela
29 C p.
 artikel
29 Glutathione peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates Arai, Kenta
29 C p.
 artikel
30 Graphical Abstract Contents Continued
29 C p.
 artikel
31 Graphical abstract TOC
29 C p.
 artikel
32 Graphical abstract TOC
29 C p.
 artikel
33 Identification and structure-activity relationship studies of small molecule inhibitors of the human cathepsin D Goyal, Sandeep
29 C p.
 artikel
34 Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism Zhu, Yan-Yan
29 C p.
 artikel
35 N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands Wannberg, Johan
29 C p.
 artikel
36 Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket Hlaváč, Matúš
29 C p.
 artikel
37 Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors Zhao, Yanmei
29 C p.
 artikel
38 Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies El-Kashef, Dina H.
29 C p.
 artikel
39 Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors Amin, Sk. Abdul
29 C p.
 artikel
40 Pyrrolo[2,3-b]pyridine-3-one derivatives as novel fibroblast growth factor receptor 4 inhibitors for the treatment of hepatocellular carcinoma Jin, Qiaomei
29 C p.
 artikel
41 Recent advances on synthesis and biological activities of aurones Sui, Guoqing
29 C p.
 artikel
42 Review of NEDDylation inhibition activity detection methods Wang, Shu-Yu
29 C p.
 artikel
43 Selective recognition of DNA parallel G-quadruplexes by 3,8a-disubstituted indolizinones Zhang, Jing-Tao
29 C p.
 artikel
44 Structure-activity relationship of novel acridone derivatives as antiproliferative agents Chen, Ji-Ning
29 C p.
 artikel
45 Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors Ma, Guixing
29 C p.
 artikel
46 Synthesis and anticancer activity of new coumarin-3-carboxylic acid derivatives as potential lactatetransportinhibitors Ji, Hong
29 C p.
 artikel
47 Synthesis and biological evaluation of all possible inosine-mixed cyclic dinucleotides that activate different hSTING variants Wang, Zhenghua
29 C p.
 artikel
48 Synthesis and evaluation of a UMI-77-based fluorescent probe for selective detecting Mcl-1 protein and imaging in living cancer cells Li, Jia
29 C p.
 artikel
49 Synthesis and evaluation of new phenyl acrylamide derivatives as potent non-nucleoside anti-HBV agents Gu, Xiaoke
29 C p.
 artikel
50 Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment Xia, Yang-Liu
29 C p.
 artikel
51 Synthesis, in vitro evaluation, and computational simulations studies of 1,2,3-triazole analogues as DPP-4 inhibitors Vo, Duy-Viet
29 C p.
 artikel
52 Synthesis of nature product kinsenoside analogues with anti-inflammatory activity Song, Wei
29 C p.
 artikel
53 Synthetic approaches to unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles and their MAO-B inhibitory activity. A review Karabelyov, Valentin
29 C p.
 artikel
54 The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization Thorarensen, Atli
29 C p.
 artikel
55 The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity Xiang, Weiguo
29 C p.
 artikel
56 The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth Song, Jianing
29 C p.
 artikel
57 Thiacalixarene based quaternary ammonium salts as promising antibacterial agents Padnya, P.L.
29 C p.
 artikel
58 Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies Ribeiro, Joana L.S.
29 C p.
 artikel
59 Tubulin inhibitory activity of a novel colchicine-binding compounds based on a dinaphthospiropyranran scaffold Sundriyal, Sandeep
29 C p.
 artikel
60 Xanthones for melanogenesis inhibition: Molecular docking and QSAR studies to understand their anti-tyrosinase activity Rosa, G.P.
29 C p.
 artikel
                             60 gevonden resultaten
 
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