| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity
|
Rasina, Dace
|
|
2018
|
26 |
9 |
p. 2488-2500
|
artikel
|
| 2 |
A new class of pyrazolo[5,1-c][1,2,4]triazines as γ-aminobutyric type A (GABAA) receptor subtype ligand: synthesis and pharmacological evaluation
|
Guerrini, Gabriella
|
|
2018
|
26 |
9 |
p. 2475-2487
|
artikel
|
| 3 |
Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids
|
Nittoli, Thomas
|
|
2018
|
26 |
9 |
p. 2271-2279
|
artikel
|
| 4 |
Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers
|
Tomassi, Stefano
|
|
2018
|
26 |
9 |
p. 2539-2550
|
artikel
|
| 5 |
Characterization of Protease-Activated Receptor (PAR) ligands: Parmodulins are reversible allosteric inhibitors of PAR1-driven calcium mobilization in endothelial cells
|
Gandhi, Disha M.
|
|
2018
|
26 |
9 |
p. 2514-2529
|
artikel
|
| 6 |
Chemical synthesis of febrifugine and analogues
|
Smullen, Shaun
|
|
2018
|
26 |
9 |
p. 2199-2220
|
artikel
|
| 7 |
Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate
|
Mondal, Dibyendu
|
|
2018
|
26 |
9 |
p. 2365-2371
|
artikel
|
| 8 |
Contents continued
|
|
|
2018
|
26 |
9 |
p. IV-XIV
|
artikel
|
| 9 |
Cyclization of PLP139-151 peptide reduces its encephalitogenic potential in experimental autoimmune encephalomyelitis
|
Lourbopoulos, Athanasios
|
|
2018
|
26 |
9 |
p. 2221-2228
|
artikel
|
| 10 |
Design and discovery of thioether and nicotinamide containing sorafenib analogues as multikinase inhibitors targeting B-Raf, B-RafV600E and VEGFR-2
|
Sun, Shaofeng
|
|
2018
|
26 |
9 |
p. 2381-2391
|
artikel
|
| 11 |
Design, in silico prioritization and biological profiling of apoptosis-inducing lactams amenable by the Castagnoli-Cushman reaction
|
Krasavin, Mikhail
|
|
2018
|
26 |
9 |
p. 2651-2673
|
artikel
|
| 12 |
Design, synthesis, and biological evaluation of new B-RafV600E kinase inhibitors
|
Wang, Peng-Fei
|
|
2018
|
26 |
9 |
p. 2372-2380
|
artikel
|
| 13 |
Design, synthesis and biological evaluation of novel hydrogen sulfide releasing capsaicin derivatives
|
Gao, Mingxiang
|
|
2018
|
26 |
9 |
p. 2632-2639
|
artikel
|
| 14 |
Design, synthesis and biological evaluation of novel tetrahydroisoquinoline derivatives as P-glycoprotein-mediated multidrug resistance inhibitors
|
Gao, Yang
|
|
2018
|
26 |
9 |
p. 2420-2427
|
artikel
|
| 15 |
Design, synthesis, and functional assessment of Cmpd-15 derivatives as negative allosteric modulators for the β2-adrenergic receptor
|
Meng, Kaicheng
|
|
2018
|
26 |
9 |
p. 2320-2330
|
artikel
|
| 16 |
Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B
|
Liu, Moyi
|
|
2018
|
26 |
9 |
p. 2621-2631
|
artikel
|
| 17 |
Design, synthesis, molecular modelling and in vitro cytotoxicity analysis of novel carbamate derivatives as inhibitors of Monoacylglycerol lipase
|
Lauria, Simone
|
|
2018
|
26 |
9 |
p. 2561-2572
|
artikel
|
| 18 |
Development of a Ga-68 labeled PET tracer with short linker for prostate-specific membrane antigen (PSMA) targeting
|
Moon, Sung-Hyun
|
|
2018
|
26 |
9 |
p. 2501-2507
|
artikel
|
| 19 |
Development of concise two-step catalytic approach towards lasofoxifene precursor nafoxidine
|
Johansson Seechurn, Carin C.C.
|
|
2018
|
26 |
9 |
p. 2691-2697
|
artikel
|
| 20 |
Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors
|
Hamajima, Toshihiro
|
|
2018
|
26 |
9 |
p. 2410-2419
|
artikel
|
| 21 |
Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells
|
Dutta, Shilpa
|
|
2018
|
26 |
9 |
p. 2428-2436
|
artikel
|
| 22 |
Discovery of new A- and B-type laxaphycins with synergistic anticancer activity
|
Cai, Weijing
|
|
2018
|
26 |
9 |
p. 2310-2319
|
artikel
|
| 23 |
Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents
|
Kojima, Takuto
|
|
2018
|
26 |
9 |
p. 2452-2465
|
artikel
|
| 24 |
Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists
|
Kojima, Takuto
|
|
2018
|
26 |
9 |
p. 2229-2250
|
artikel
|
| 25 |
DNA sequence-specific ligands. XVII. Synthesis, spectral properties, virological and biochemical studies of fluorescent dimeric bisbenzimidazoles DBA(n)
|
Koval, Vasiliy S.
|
|
2018
|
26 |
9 |
p. 2302-2309
|
artikel
|
| 26 |
Editorial Board
|
|
|
2018
|
26 |
9 |
p. ii
|
artikel
|
| 27 |
Graphical abstract TOC
|
|
|
2018
|
26 |
9 |
p. OBC
|
artikel
|
| 28 |
Graphical abstract TOC
|
|
|
2018
|
26 |
9 |
p. IBC
|
artikel
|
| 29 |
Hydrophobic structure of hairpin ten-ring pyrrole-imidazole polyamides enhances tumor tissue accumulation/retention in vivo
|
Inoue, Takahiro
|
|
2018
|
26 |
9 |
p. 2337-2344
|
artikel
|
| 30 |
Inhibitors of dihydrofolate reductase as antitumor agents: design, synthesis and biological evaluation of a series of novel nonclassical 6-substituted pyrido[3,2-d]pyrimidines with a three- to five-carbon bridge
|
Li, Hao
|
|
2018
|
26 |
9 |
p. 2674-2685
|
artikel
|
| 31 |
Investigation of novel pyrazole carboxamides as new apoptosis inducers on neuronal cells in Helicoverpa zea
|
Ren, Yuanhang
|
|
2018
|
26 |
9 |
p. 2280-2286
|
artikel
|
| 32 |
Kinase-catalyzed biotinylation of DNA
|
Anthony, Thilani M.
|
|
2018
|
26 |
9 |
p. 2331-2336
|
artikel
|
| 33 |
Novel fatty acid chain modified GLP-1 derivatives with prolonged in vivo glucose-lowering ability and balanced glucoregulatory activity
|
Cai, Xingguang
|
|
2018
|
26 |
9 |
p. 2599-2609
|
artikel
|
| 34 |
Novel naphthyloxy derivatives – Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation
|
Łażewska, Dorota
|
|
2018
|
26 |
9 |
p. 2573-2585
|
artikel
|
| 35 |
Optimized allosteric inhibition of engineered protein tyrosine phosphatases with an expanded palette of biarsenical small molecules
|
Korntner, Samuel
|
|
2018
|
26 |
9 |
p. 2610-2620
|
artikel
|
| 36 |
Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease
|
Pagare, Piyusha P.
|
|
2018
|
26 |
9 |
p. 2530-2538
|
artikel
|
| 37 |
Selective binding and controlled release of anticancer drugs by polyanionic cyclodextrins
|
Cheng, Jian-Guang
|
|
2018
|
26 |
9 |
p. 2287-2290
|
artikel
|
| 38 |
Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance
|
Vanarotti, Murugendra
|
|
2018
|
26 |
9 |
p. 2345-2353
|
artikel
|
| 39 |
Structure–activity relationships of succinimidyl-Cys-C(O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen
|
Matsuoka, Daiko
|
|
2018
|
26 |
9 |
p. 2291-2301
|
artikel
|
| 40 |
Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
|
Xiang, Weiguo
|
|
2018
|
26 |
9 |
p. 2437-2451
|
artikel
|
| 41 |
Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca2+ overload, as a multitarget strategy for the treatment of Alzheimer’s disease
|
Gonzalez, Dorleta
|
|
2018
|
26 |
9 |
p. 2551-2560
|
artikel
|
| 42 |
4-Substituted carbamazepine derivatives: Conformational analysis and sodium channel-blocking properties
|
Kanase, Yuki
|
|
2018
|
26 |
9 |
p. 2508-2513
|
artikel
|
| 43 |
Syntheses and structure-activity relationships on antibacterial and anti-ulcerative colitis properties of quaternary 13-substituted palmatines and 8-oxo-13-substituted dihydropalmatines
|
Song, Li
|
|
2018
|
26 |
9 |
p. 2586-2598
|
artikel
|
| 44 |
Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones
|
Woodard, John L.
|
|
2018
|
26 |
9 |
p. 2354-2364
|
artikel
|
| 45 |
Synthesis and biological evaluation of aminothiazoles against Histoplasma capsulatum and Cryptococcus neoformans
|
Ishita, Keisuke
|
|
2018
|
26 |
9 |
p. 2251-2261
|
artikel
|
| 46 |
Synthesis and inhibitory activity of mechanism-based 4-coumaroyl-CoA ligase inhibitors
|
Watanabe, Bunta
|
|
2018
|
26 |
9 |
p. 2466-2474
|
artikel
|
| 47 |
Synthesis of enantiopure antiobesity drug lorcaserin
|
Smilovic, Ivana Gazic
|
|
2018
|
26 |
9 |
p. 2686-2690
|
artikel
|
| 48 |
Synthesis of S-linked NeuAc-α(2-6)-di-LacNAc bearing liposomes for H1N1 influenza virus inhibition assays
|
Cheng, Hou-Wen
|
|
2018
|
26 |
9 |
p. 2262-2270
|
artikel
|
| 49 |
Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents
|
Shah, Khushbu
|
|
2018
|
26 |
9 |
p. 2640-2650
|
artikel
|
| 50 |
Terpenoids isolated from Chinese liverworts Lepidozia reptans and their anti-inflammatory activity
|
Li, Siwen
|
|
2018
|
26 |
9 |
p. 2392-2400
|
artikel
|
| 51 |
Towards designing a synthetic antituberculosis vaccine: The Rv3587c peptide inhibits mycobacterial entry to host cells
|
Carabali-Isajar, Mary Lilian
|
|
2018
|
26 |
9 |
p. 2401-2409
|
artikel
|
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