| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin
|
Çapcı Karagöz, Aysun
|
|
2018
|
26 |
12 |
p. 3610-3618
|
artikel
|
| 2 |
An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assay
|
Stevenson, Ralph J.
|
|
2018
|
26 |
12 |
p. 3406-3413
|
artikel
|
| 3 |
Anthranilic diamides derivatives as potential ryanodine receptor modulators: Synthesis, biological evaluation and structure activity relationship
|
Liu, Jing-Bo
|
|
2018
|
26 |
12 |
p. 3541-3550
|
artikel
|
| 4 |
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair
|
Prabha, B.
|
|
2018
|
26 |
12 |
p. 3461-3467
|
artikel
|
| 5 |
Applications of a novel biodetection system to saliva using protein fingerprints with data processing
|
Tominaga, Yuki
|
|
2018
|
26 |
12 |
p. 3210-3216
|
artikel
|
| 6 |
Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonist
|
Sagratini, Gianni
|
|
2018
|
26 |
12 |
p. 3502-3513
|
artikel
|
| 7 |
Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imaging
|
Kaide, Sho
|
|
2018
|
26 |
12 |
p. 3352-3358
|
artikel
|
| 8 |
Corrigendum to “A study of 2-component i, i + 3 peptide stapling using thioethers” [Bioorg. Med. Chem. 26(6) (2018) 1203–1205]
|
St. Louis, Lauren E.
|
|
2018
|
26 |
12 |
p. 3727
|
artikel
|
| 9 |
Corrigendum to “Structure–activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures” [Bioorg. Med. Chem. 23 (2015) 1601–1612]
|
Nowotarski, Shannon L.
|
|
2018
|
26 |
12 |
p. 3728-3729
|
artikel
|
| 10 |
Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptors
|
Remesic, Michael
|
|
2018
|
26 |
12 |
p. 3664-3667
|
artikel
|
| 11 |
Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure
|
Boulahjar, Rajaa
|
|
2018
|
26 |
12 |
p. 3296-3307
|
artikel
|
| 12 |
Design and synthesis of new antitumor agents with the 1,7-epoxycyclononane framework. Study of their anticancer action mechanism by a model compound
|
Montaña, Ángel M.
|
|
2018
|
26 |
12 |
p. 3379-3398
|
artikel
|
| 13 |
Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agents
|
Mostofi, Manizheh
|
|
2018
|
26 |
12 |
p. 3076-3095
|
artikel
|
| 14 |
Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonists
|
Oka, Hiromasa
|
|
2018
|
26 |
12 |
p. 3716-3726
|
artikel
|
| 15 |
Design, synthesis and biological evaluation of phosphopeptides as Polo-like kinase 1 Polo-box domain inhibitors
|
Lin, Tong-yuan
|
|
2018
|
26 |
12 |
p. 3429-3437
|
artikel
|
| 16 |
Design, synthesis and biological evaluation of pyrimidine derivatives as novel CDK2 inhibitors that induce apoptosis and cell cycle arrest in breast cancer cells
|
Wang, Yiting
|
|
2018
|
26 |
12 |
p. 3491-3501
|
artikel
|
| 17 |
Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51
|
Zhao, Shizhen
|
|
2018
|
26 |
12 |
p. 3242-3253
|
artikel
|
| 18 |
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
|
Liu, Wenwen
|
|
2018
|
26 |
12 |
p. 3117-3125
|
artikel
|
| 19 |
Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells
|
Batran, Rasha Z.
|
|
2018
|
26 |
12 |
p. 3474-3490
|
artikel
|
| 20 |
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrido[4,3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy
|
Qin, Li-Huai
|
|
2018
|
26 |
12 |
p. 3559-3572
|
artikel
|
| 21 |
Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile
|
Tokuhara, Hidekazu
|
|
2018
|
26 |
12 |
p. 3261-3286
|
artikel
|
| 22 |
Discovery of bicyclo[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors
|
Ueda, Hiroki
|
|
2018
|
26 |
12 |
p. 3345-3351
|
artikel
|
| 23 |
Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators
|
Gerlach, Kai
|
|
2018
|
26 |
12 |
p. 3227-3241
|
artikel
|
| 24 |
Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5,7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospective
|
Ponnusamy, Thangarasu
|
|
2018
|
26 |
12 |
p. 3438-3452
|
artikel
|
| 25 |
Dual emissive bispyrene peptide probes for highly sensitive measurements of trypsin activity and evaluation of trypsin inhibitors
|
Sato, Daisuke
|
|
2018
|
26 |
12 |
p. 3468-3473
|
artikel
|
| 26 |
Editorial Board
|
|
|
2018
|
26 |
12 |
p. ii
|
artikel
|
| 27 |
Efficiency of newly prepared thiazole derivatives against some cutaneous fungi
|
Ouf, Salama A.
|
|
2018
|
26 |
12 |
p. 3287-3295
|
artikel
|
| 28 |
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus
|
Liang, Hai
|
|
2018
|
26 |
12 |
p. 3453-3460
|
artikel
|
| 29 |
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs
|
Pileggi, Elisa
|
|
2018
|
26 |
12 |
p. 3596-3609
|
artikel
|
| 30 |
Exploiting polarity and chirality to probe the Hsp90 C-terminus
|
Forsberg, Leah K.
|
|
2018
|
26 |
12 |
p. 3096-3110
|
artikel
|
| 31 |
Facilely accessible quinoline derivatives as potent antibacterial agents
|
Teng, Peng
|
|
2018
|
26 |
12 |
p. 3573-3579
|
artikel
|
| 32 |
Graphical abstract TOC
|
|
|
2018
|
26 |
12 |
p. IBC
|
artikel
|
| 33 |
Graphical abstract TOC
|
|
|
2018
|
26 |
12 |
p. OBC
|
artikel
|
| 34 |
Graphical abstract TOC continued
|
|
|
2018
|
26 |
12 |
p. III-XVI
|
artikel
|
| 35 |
Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A1 and A2A adenosine receptor antagonists/inverse agonists
|
Varano, Flavia
|
|
2018
|
26 |
12 |
p. 3688-3695
|
artikel
|
| 36 |
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich’s ataxia
|
Khdour, Omar M.
|
|
2018
|
26 |
12 |
p. 3359-3369
|
artikel
|
| 37 |
Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescence
|
Fuchi, Yasufumi
|
|
2018
|
26 |
12 |
p. 3254-3260
|
artikel
|
| 38 |
Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazole
|
Naaz, Farha
|
|
2018
|
26 |
12 |
p. 3414-3428
|
artikel
|
| 39 |
Novel amidrazone derivatives: Design, synthesis and activity evaluation
|
Zhou, Hua
|
|
2018
|
26 |
12 |
p. 3158-3165
|
artikel
|
| 40 |
Novel carbamate-linked quaternary ammonium lipids containing unsaturated hydrophobic chains for gene delivery
|
Zhou, Hengjun
|
|
2018
|
26 |
12 |
p. 3535-3540
|
artikel
|
| 41 |
Novel 8-hydroxyquinoline derivatives targeting β-amyloid aggregation, metal chelation and oxidative stress against Alzheimer’s disease
|
Yang, Xuelian
|
|
2018
|
26 |
12 |
p. 3191-3201
|
artikel
|
| 42 |
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry
|
Cao, Jiangying
|
|
2018
|
26 |
12 |
p. 3145-3157
|
artikel
|
| 43 |
Novel oxazolxanthone derivatives as a new type of α-glucosidase inhibitor: synthesis, activities, inhibitory modes and synergetic effect
|
Ding, Sen-Miao
|
|
2018
|
26 |
12 |
p. 3370-3378
|
artikel
|
| 44 |
Optimized synthesis and antiproliferative activity of desTHPdactylolides
|
Chen, Guanglin
|
|
2018
|
26 |
12 |
p. 3514-3520
|
artikel
|
| 45 |
Osteoblastic differentiation on hydrogels fabricated from Ca2+-responsive self-assembling peptides functionalized with bioactive peptides
|
Tsutsumi, Hiroshi
|
|
2018
|
26 |
12 |
p. 3126-3132
|
artikel
|
| 46 |
Pyrroloquinoline scaffold-based 5-HT6R ligands: Synthesis, quantum chemical and molecular dynamic studies, and influence of nitrogen atom position in the scaffold on affinity
|
Grychowska, Katarzyna
|
|
2018
|
26 |
12 |
p. 3588-3595
|
artikel
|
| 47 |
Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase
|
Taha, Muhammad
|
|
2018
|
26 |
12 |
p. 3654-3663
|
artikel
|
| 48 |
Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitors
|
Borysko, Petro
|
|
2018
|
26 |
12 |
p. 3399-3405
|
artikel
|
| 49 |
Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors
|
Ngo, Van T.H.
|
|
2018
|
26 |
12 |
p. 3133-3144
|
artikel
|
| 50 |
Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregation
|
Tsunoda, Tatsuhiko
|
|
2018
|
26 |
12 |
p. 3202-3209
|
artikel
|
| 51 |
Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones
|
Murafuji, Hidenobu
|
|
2018
|
26 |
12 |
p. 3639-3653
|
artikel
|
| 52 |
Synthesis and biological evaluation of 2,4-disubstituted phthalazinones as Aurora kinase inhibitors
|
Wang, Wei
|
|
2018
|
26 |
12 |
p. 3217-3226
|
artikel
|
| 53 |
Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3,4-d]pyrimidine scaffold
|
Zhang, Hao
|
|
2018
|
26 |
12 |
p. 3619-3633
|
artikel
|
| 54 |
Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors
|
Tóth, Krisztián
|
|
2018
|
26 |
12 |
p. 3668-3687
|
artikel
|
| 55 |
Synthesis and biophysical properties of 5′-thio-2′,4′-BNA/LNA oligonucleotide
|
Islam, Md Ariful
|
|
2018
|
26 |
12 |
p. 3634-3638
|
artikel
|
| 56 |
Synthesis and characterization of radioiodinated 3-phenethyl-2-indolinone derivatives for SPECT imaging of survivin in tumors
|
Ishikawa, Natsumi
|
|
2018
|
26 |
12 |
p. 3111-3116
|
artikel
|
| 57 |
Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors
|
Wang, Chenglin
|
|
2018
|
26 |
12 |
p. 3308-3320
|
artikel
|
| 58 |
Synthesis and structure–activity relationship studies of MI-2 analogues as MALT1 inhibitors
|
Wu, Guolin
|
|
2018
|
26 |
12 |
p. 3321-3344
|
artikel
|
| 59 |
Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides
|
Laqua, Katja
|
|
2018
|
26 |
12 |
p. 3166-3190
|
artikel
|
| 60 |
Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
|
Stepniewski, Tomasz Maciej
|
|
2018
|
26 |
12 |
p. 3580-3587
|
artikel
|
| 61 |
Synthesis of 4′-C-aminoalkyl-2′-O-methyl modified RNA and their biological properties
|
Koizumi, Kana
|
|
2018
|
26 |
12 |
p. 3521-3534
|
artikel
|
| 62 |
Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis
|
Sajid-ur-Rehman,
|
|
2018
|
26 |
12 |
p. 3707-3715
|
artikel
|
| 63 |
Synthesis, structure-activity relationship and molecular docking studies of 3-O-flavonol glycosides as cholinesterase inhibitors
|
Mughal, Ehsan Ullah
|
|
2018
|
26 |
12 |
p. 3696-3706
|
artikel
|
| 64 |
The recent progress of isoxazole in medicinal chemistry
|
Zhu, Jie
|
|
2018
|
26 |
12 |
p. 3065-3075
|
artikel
|
| 65 |
Vinyldiaminotriazine-acridine conjugate as G-quadruplex alkylating agent
|
Hazemi, Madoka E.
|
|
2018
|
26 |
12 |
p. 3551-3558
|
artikel
|
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