| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements
|
Taban, Ismail M.
|
|
2017
|
25 |
20 |
p. 5629-5636
|
artikel
|
| 2 |
A novel class of Plasmodial ClpP protease inhibitors as potential antimalarial agents
|
Mundra, Sourabh
|
|
2017
|
25 |
20 |
p. 5662-5677
|
artikel
|
| 3 |
A novel delocalized lipophilic cation-chlorambucil conjugate inhibits P-glycoprotein in HepG2/ADM cells
|
Liu, Teng
|
|
2017
|
25 |
20 |
p. 5461-5467
|
artikel
|
| 4 |
A prodrug design for improved oral absorption and reduced hepatic interaction
|
Ahmed, Gulzar
|
|
2017
|
25 |
20 |
p. 5569-5575
|
artikel
|
| 5 |
β-Arrestin biased dopamine D2 receptor partial agonists: Synthesis and pharmacological evaluation
|
Männel, Barbara
|
|
2017
|
25 |
20 |
p. 5613-5628
|
artikel
|
| 6 |
Axially substituted silicon(IV) phthalocyanine and its quaternized derivative as photosensitizers towards tumor cells and bacterial pathogens
|
Ömeroğlu, İpek
|
|
2017
|
25 |
20 |
p. 5415-5422
|
artikel
|
| 7 |
Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities
|
Thakkar, Sampark S.
|
|
2017
|
25 |
20 |
p. 5396-5406
|
artikel
|
| 8 |
Biological evaluation of 2-pyrazolinyl-1-carbothioamide derivatives against HCT116 human colorectal cancer cell lines and elucidation on QSAR and molecular binding modes
|
Kim, Beom Soo
|
|
2017
|
25 |
20 |
p. 5423-5432
|
artikel
|
| 9 |
Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands
|
Łażewska, Dorota
|
|
2017
|
25 |
20 |
p. 5341-5354
|
artikel
|
| 10 |
Characterisation of a novel coumarin-based fluorescent probe for monitoring nitric oxide production in macrophages
|
Sadek, Maiada M.
|
|
2017
|
25 |
20 |
p. 5743-5748
|
artikel
|
| 11 |
Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs fluorinated fungal metabolites
|
Paguigan, Noemi D.
|
|
2017
|
25 |
20 |
p. 5238-5246
|
artikel
|
| 12 |
Conjugates of 18β-glycyrrhetinic acid derivatives with 3-(1H-benzo[d]imidazol-2-yl)propanoic acid as Pin1 inhibitors displaying anti-prostate cancer ability
|
Li, Kun
|
|
2017
|
25 |
20 |
p. 5441-5451
|
artikel
|
| 13 |
Constructing novel dihydrofuran and dihydroisoxazole analogues of isocombretastatin-4 as tubulin polymerization inhibitors through [3+2] reactions
|
Song, Ming-Yu
|
|
2017
|
25 |
20 |
p. 5290-5302
|
artikel
|
| 14 |
Corrigenda to “Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents” [Bioorg Med Chem 24 (2016) 5172–5182]
|
Song, Lijun
|
|
2017
|
25 |
20 |
p. 5889
|
artikel
|
| 15 |
Design and optimization of N-acylhydrazone pyrimidine derivatives as E. coli PDHc E1 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study
|
He, Haifeng
|
|
2017
|
25 |
20 |
p. 5652-5661
|
artikel
|
| 16 |
Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents
|
Torikai, Kohei
|
|
2017
|
25 |
20 |
p. 5216-5237
|
artikel
|
| 17 |
Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold
|
Wang, Min
|
|
2017
|
25 |
20 |
p. 5754-5763
|
artikel
|
| 18 |
Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines
|
Arepalli, Sateesh Kumar
|
|
2017
|
25 |
20 |
p. 5586-5597
|
artikel
|
| 19 |
Design, synthesis and biological evaluation of novel antitumor spirotetrahydrothiopyran–oxindole derivatives as potent p53-MDM2 inhibitors
|
Ji, Changjin
|
|
2017
|
25 |
20 |
p. 5268-5277
|
artikel
|
| 20 |
Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors
|
Angapelly, Srinivas
|
|
2017
|
25 |
20 |
p. 5726-5732
|
artikel
|
| 21 |
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents
|
Roh, Jaroslav
|
|
2017
|
25 |
20 |
p. 5468-5476
|
artikel
|
| 22 |
Discovery of berberine based derivatives as anti-influenza agent through blocking of neuraminidase
|
Enkhtaivan, Gansukh
|
|
2017
|
25 |
20 |
p. 5185-5193
|
artikel
|
| 23 |
Discovery of non-zwitterionic aryl sulfonamides as Nav1.7 inhibitors with efficacy in preclinical behavioral models and translational measures of nociceptive neuron activation
|
Wu, Yong-Jin
|
|
2017
|
25 |
20 |
p. 5490-5505
|
artikel
|
| 24 |
Discovery of novel inhibitors of multidrug-resistant Acinetobacter baumannii
|
Soojhawon, Iswarduth
|
|
2017
|
25 |
20 |
p. 5477-5482
|
artikel
|
| 25 |
Discovery of tricyclic dipyrrolopyridine derivatives as novel JAK inhibitors
|
Yamagishi, Hiroaki
|
|
2017
|
25 |
20 |
p. 5311-5326
|
artikel
|
| 26 |
Editorial board
|
|
|
2017
|
25 |
20 |
p. IFC
|
artikel
|
| 27 |
Eudesmane sesquiterpenes from Chinese liverwort are substrates of Cdrs and display antifungal activity by targeting Erg6 and Erg11 of Candida albicans
|
Li, Siwen
|
|
2017
|
25 |
20 |
p. 5764-5771
|
artikel
|
| 28 |
Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes
|
Jürgens, Sophie
|
|
2017
|
25 |
20 |
p. 5452-5460
|
artikel
|
| 29 |
Facile alkylation of 4-nitrobenzotriazole and its platelet aggregation inhibitory activity
|
Singh, Dhandeep
|
|
2017
|
25 |
20 |
p. 5260-5267
|
artikel
|
| 30 |
Highly potent antiobesity effect of a short-length peptide YY analog in mice
|
Nishizawa, Naoki
|
|
2017
|
25 |
20 |
p. 5718-5725
|
artikel
|
| 31 |
1-Hydroxypyrido[2,3-d]pyrimidin-2(1H)-ones as novel selective HIV integrase inhibitors obtained via privileged substructure-based compound libraries
|
Gao, Ping
|
|
2017
|
25 |
20 |
p. 5779-5789
|
artikel
|
| 32 |
Identification of highly selective and potent orexin receptor 1 antagonists derived from a dual orexin receptor 1/2 antagonist based on the structural framework of pyrazoylethylbenzamide
|
Futamura, Aya
|
|
2017
|
25 |
20 |
p. 5203-5215
|
artikel
|
| 33 |
Identification of pyrazolopyrimidine arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists
|
Miah, Afjal H.
|
|
2017
|
25 |
20 |
p. 5327-5340
|
artikel
|
| 34 |
Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide
|
Yang, Jie
|
|
2017
|
25 |
20 |
p. 5838-5848
|
artikel
|
| 35 |
Interrogation of side chain biases for oligomannose recognition by antibody 2G12 via structure-guided phage display libraries
|
Lin, Tsung-Yi
|
|
2017
|
25 |
20 |
p. 5790-5798
|
artikel
|
| 36 |
In vitro antitumor activity of novel benzimidazole-based Cu(II) complexes
|
Hu, Jiyong
|
|
2017
|
25 |
20 |
p. 5733-5742
|
artikel
|
| 37 |
Linker structure-activity relationships in fluorodeoxyglucose chlorambucil conjugates for tumor-targeted chemotherapy
|
El Hilali, Mostafa
|
|
2017
|
25 |
20 |
p. 5692-5708
|
artikel
|
| 38 |
Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction
|
Roy Chowdhury, Sandipan
|
|
2017
|
25 |
20 |
p. 5537-5547
|
artikel
|
| 39 |
meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity
|
Reyes-Melo, Karen
|
|
2017
|
25 |
20 |
p. 5247-5259
|
artikel
|
| 40 |
Methyl propiolate and 3-butynone: Starting points for synthesis of amphiphilic 1,2,3-triazole peptidomimetics for antimicrobial evaluation
|
Bakka, Thomas A.
|
|
2017
|
25 |
20 |
p. 5380-5395
|
artikel
|
| 41 |
Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2′s-hydroxy-3′s-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors
|
Kandalkar, Sachin R.
|
|
2017
|
25 |
20 |
p. 5799-5819
|
artikel
|
| 42 |
New 5-HT1A, 5HT2A and 5HT2C receptor ligands containing a picolinic nucleus: Synthesis, in vitro and in vivo pharmacological evaluation
|
Fiorino, Ferdinando
|
|
2017
|
25 |
20 |
p. 5820-5837
|
artikel
|
| 43 |
Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl4-induced liver injury in mice
|
Lin, Yan
|
|
2017
|
25 |
20 |
p. 5522-5530
|
artikel
|
| 44 |
1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation
|
Xu, Guangsen
|
|
2017
|
25 |
20 |
p. 5548-5556
|
artikel
|
| 45 |
Picomolar inhibition of β-galactosidase (bovine liver) attributed to loop closure
|
Pickens, Jessica B.
|
|
2017
|
25 |
20 |
p. 5194-5202
|
artikel
|
| 46 |
Propolis reversed cigarette smoke-induced emphysema through macrophage alternative activation independent of Nrf2
|
Barroso, Marina Valente
|
|
2017
|
25 |
20 |
p. 5557-5568
|
artikel
|
| 47 |
Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action
|
Gouda, Ahmed M.
|
|
2017
|
25 |
20 |
p. 5637-5651
|
artikel
|
| 48 |
Radiosynthesis and preclinical PET evaluation of 89Zr-nivolumab (BMS-936558) in healthy non-human primates
|
Cole, Erin L.
|
|
2017
|
25 |
20 |
p. 5407-5414
|
artikel
|
| 49 |
Rational design of conformationally constrained oxazolidinone-fused 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors
|
Song, Gaopeng
|
|
2017
|
25 |
20 |
p. 5709-5717
|
artikel
|
| 50 |
Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity
|
Rath, Susann
|
|
2017
|
25 |
20 |
p. 5365-5372
|
artikel
|
| 51 |
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects
|
Damonte, Patrizia
|
|
2017
|
25 |
20 |
p. 5849-5858
|
artikel
|
| 52 |
Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria
|
Barker, William T.
|
|
2017
|
25 |
20 |
p. 5749-5753
|
artikel
|
| 53 |
Structural evidence for the DPPH radical-scavenging mechanism of 2-O-α-d-glucopyranosyl-l-ascorbic acid
|
Tai, Akihiro
|
|
2017
|
25 |
20 |
p. 5303-5310
|
artikel
|
| 54 |
Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells
|
Kimura, Hiroyuki
|
|
2017
|
25 |
20 |
p. 5772-5778
|
artikel
|
| 55 |
Synthesis and biological evaluation of 8-aryl-2-morpholino-7-O-substituted benzo[e][1,3]oxazin-4-ones against DNA-PK, PI3K, PDE3A enzymes and platelet aggregation
|
Saifuzzaman, Md.
|
|
2017
|
25 |
20 |
p. 5531-5536
|
artikel
|
| 56 |
Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474
|
Gamage, Swarna A.
|
|
2017
|
25 |
20 |
p. 5859-5874
|
artikel
|
| 57 |
Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties
|
Angeli, Andrea
|
|
2017
|
25 |
20 |
p. 5373-5379
|
artikel
|
| 58 |
Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity
|
Brockway, Anthony J.
|
|
2017
|
25 |
20 |
p. 5433-5440
|
artikel
|
| 59 |
Synthesis and evaluation of radioiodinated 1-{2-[5-(2-methoxyethoxy)-1H-benzo[d]imidazol-1-yl]quinolin-8-yl}piperidin-4-amine derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging
|
Effendi, Nurmaya
|
|
2017
|
25 |
20 |
p. 5576-5585
|
artikel
|
| 60 |
Synthesis and preliminary in vivo evaluation of new [18F]fluoro-inositols as Positron Emission Tomography radiotracers
|
Collet, Charlotte
|
|
2017
|
25 |
20 |
p. 5603-5612
|
artikel
|
| 61 |
Synthesis of amide isosteres of schweinfurthin-based stilbenes
|
Stockdale, David P.
|
|
2017
|
25 |
20 |
p. 5483-5489
|
artikel
|
| 62 |
Synthesis of damaged DNA containing the oxidative lesion 3′-oxothymidine
|
Bedi, Mel F.
|
|
2017
|
25 |
20 |
p. 5598-5602
|
artikel
|
| 63 |
Synthesis of novel flavonoid alkaloids as α-glucosidase inhibitors
|
Zhen, Jing
|
|
2017
|
25 |
20 |
p. 5355-5364
|
artikel
|
| 64 |
Synthesis, pharmacological activities and molecular docking studies of pyrazolyltriazoles as anti-bacterial and anti-inflammatory agents
|
Dayakar, Cherupally
|
|
2017
|
25 |
20 |
p. 5678-5691
|
artikel
|
| 65 |
Synthesis, pH dependent, plasma and enzymatic stability of bergenin prodrugs for potential use against rheumatoid arthritis
|
Singh, Rohit
|
|
2017
|
25 |
20 |
p. 5513-5521
|
artikel
|
| 66 |
The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrPC to PrPSc with lower IC50 in ScN2a cells
|
Pagadala, Nataraj S.
|
|
2017
|
25 |
20 |
p. 5875-5888
|
artikel
|
| 67 |
The design and synthesis of a novel compound of berberine and baicalein that inhibits the efficacy of lipid accumulation in 3T3-L1 adipocytes
|
Hao, Mengjiao
|
|
2017
|
25 |
20 |
p. 5506-5512
|
artikel
|
| 68 |
Triple reuptake inhibitors: Design, synthesis and structure–activity relationship of benzylpiperidine–tetrazoles
|
Paudel, Suresh
|
|
2017
|
25 |
20 |
p. 5278-5289
|
artikel
|
| 69 |
UPAR targeted molecular imaging of cancers with small molecule-based probes
|
Ding, Feng
|
|
2017
|
25 |
20 |
p. 5179-5184
|
artikel
|
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