| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A facile stereoselective synthesis of dispiro-indeno pyrrolidine/pyrrolothiazole–thiochroman hybrids and evaluation of their antimycobacterial, anticancer and AchE inhibitory activities
|
Bharkavi, Chelliah
|
|
2016
|
24 |
22 |
p. 5873-5883
11 p.
|
artikel
|
| 2 |
Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody–drug conjugates
|
Giddens, Anna C.
|
|
2016
|
24 |
22 |
p. 6075-6081
7 p.
|
artikel
|
| 3 |
ArgTX-636, a polyamine isolated from spider venom: A novel class of melanogenesis inhibitors
|
Verdoni, Marion
|
|
2016
|
24 |
22 |
p. 5685-5692
8 p.
|
artikel
|
| 4 |
Biological evaluation of tetracationic compounds based on two 1,4-diazabicyclo[2.2.2]octane moieties connected by different linkers
|
Burakova, Ekaterina A.
|
|
2016
|
24 |
22 |
p. 6012-6020
9 p.
|
artikel
|
| 5 |
Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents
|
dos Santos Filho, José Maurício
|
|
2016
|
24 |
22 |
p. 5693-5701
9 p.
|
artikel
|
| 6 |
Cyclen-based Gd3+ complexes as MRI contrast agents: Relaxivity enhancement and ligand design
|
Rashid, Haroon Ur
|
|
2016
|
24 |
22 |
p. 5663-5684
22 p.
|
artikel
|
| 7 |
Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter
|
Lougiakis, Nikolaos
|
|
2016
|
24 |
22 |
p. 5941-5952
12 p.
|
artikel
|
| 8 |
Design, synthesis and biological evaluation of lapachol derivatives possessing indole scaffolds as topoisomerase I inhibitors
|
Zhang, Chong
|
|
2016
|
24 |
22 |
p. 5781-5786
6 p.
|
artikel
|
| 9 |
Design, synthesis and biological evaluation of potential antibacterial butyrolactones
|
Sweidan, Alaa
|
|
2016
|
24 |
22 |
p. 5823-5833
11 p.
|
artikel
|
| 10 |
Design, synthesis and evaluation of anti-CD123 antibody drug conjugates
|
Li, Bin
|
|
2016
|
24 |
22 |
p. 5855-5860
6 p.
|
artikel
|
| 11 |
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold
|
Xu, Zhixiang
|
|
2016
|
24 |
22 |
p. 5861-5872
12 p.
|
artikel
|
| 12 |
Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity
|
Curreli, Francesca
|
|
2016
|
24 |
22 |
p. 5988-6003
16 p.
|
artikel
|
| 13 |
Direct protein–protein conjugation by genetically introducing bioorthogonal functional groups into proteins
|
Kim, Sanggil
|
|
2016
|
24 |
22 |
p. 5816-5822
7 p.
|
artikel
|
| 14 |
Discovery, design and synthesis of 6H-anthra[1,9-cd]isoxazol-6-one scaffold as G9a inhibitor through a combination of shape-based virtual screening and structure-based molecular modification
|
Chen, Wei-Lin
|
|
2016
|
24 |
22 |
p. 6102-6108
7 p.
|
artikel
|
| 15 |
Discovery of a novel chimeric ubenimex–gemcitabine with potent oral antitumor activity
|
Jiang, Yuqi
|
|
2016
|
24 |
22 |
p. 5787-5795
9 p.
|
artikel
|
| 16 |
Editorial board
|
|
|
2016
|
24 |
22 |
p. IFC-
1 p.
|
artikel
|
| 17 |
Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization
|
Arnatt, Christopher K.
|
|
2016
|
24 |
22 |
p. 5969-5987
19 p.
|
artikel
|
| 18 |
Inhibition of the metastatic progression of breast and colorectal cancer in vitro and in vivo in murine model by the oxidovanadium(IV) complex with luteolin
|
Naso, Luciana G.
|
|
2016
|
24 |
22 |
p. 6004-6011
8 p.
|
artikel
|
| 19 |
Insights into tyrosinase inhibition by compounds isolated from Greyia radlkoferi Szyszyl using biological activity, molecular docking and gene expression analysis
|
Lall, Namrita
|
|
2016
|
24 |
22 |
p. 5953-5959
7 p.
|
artikel
|
| 20 |
Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor
|
Begum, Anjuman Ara
|
|
2016
|
24 |
22 |
p. 5834-5841
8 p.
|
artikel
|
| 21 |
In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors
|
Balasubramanian, Gopalan
|
|
2016
|
24 |
22 |
p. 5702-5716
15 p.
|
artikel
|
| 22 |
Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings
|
Moise, Iuliana-Monica
|
|
2016
|
24 |
22 |
p. 6021-6030
10 p.
|
artikel
|
| 23 |
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer’s disease
|
Wei, Shenqi
|
|
2016
|
24 |
22 |
p. 6031-6039
9 p.
|
artikel
|
| 24 |
Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson’s disease
|
Wang, Zhimin
|
|
2016
|
24 |
22 |
p. 5929-5940
12 p.
|
artikel
|
| 25 |
Novel approach of fragment-based lead discovery applied to renin inhibitors
|
Tawada, Michiko
|
|
2016
|
24 |
22 |
p. 6066-6074
9 p.
|
artikel
|
| 26 |
On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions
|
Escolà, Anna
|
|
2016
|
24 |
22 |
p. 5804-5815
12 p.
|
artikel
|
| 27 |
Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors
|
Hauck, Stefanie
|
|
2016
|
24 |
22 |
p. 5717-5729
13 p.
|
artikel
|
| 28 |
(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies
|
Ebrahim, Hassan Y.
|
|
2016
|
24 |
22 |
p. 5748-5761
14 p.
|
artikel
|
| 29 |
Sobetirome prodrug esters with enhanced blood–brain barrier permeability
|
Placzek, Andrew T.
|
|
2016
|
24 |
22 |
p. 5842-5854
13 p.
|
artikel
|
| 30 |
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors
|
Imaeda, Yasuhiro
|
|
2016
|
24 |
22 |
p. 5771-5780
10 p.
|
artikel
|
| 31 |
Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)–WDR5 interaction
|
Li, Dong-Dong
|
|
2016
|
24 |
22 |
p. 6109-6118
10 p.
|
artikel
|
| 32 |
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
|
Igumnova, Elizaveta M.
|
|
2016
|
24 |
22 |
p. 5884-5894
11 p.
|
artikel
|
| 33 |
Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors
|
Kim, Ho Shin
|
|
2016
|
24 |
22 |
p. 6082-6093
12 p.
|
artikel
|
| 34 |
Synthesis and biological evaluation of furocoumarin derivatives on melanin synthesis in murine B16 cells for the treatment of vitiligo
|
Niu, Chao
|
|
2016
|
24 |
22 |
p. 5960-5968
9 p.
|
artikel
|
| 35 |
Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer’s disease
|
Barbosa, Flavio A.R.
|
|
2016
|
24 |
22 |
p. 5762-5770
9 p.
|
artikel
|
| 36 |
Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors
|
Ofori, Edward
|
|
2016
|
24 |
22 |
p. 5730-5740
11 p.
|
artikel
|
| 37 |
Synthesis and pharmacological evaluation of conformationally constrained glutamic acid higher homologues
|
Tamborini, Lucia
|
|
2016
|
24 |
22 |
p. 5741-5747
7 p.
|
artikel
|
| 38 |
Synthesis and Pin1 inhibitory activity of thiazole derivatives
|
Zhao, Hailong
|
|
2016
|
24 |
22 |
p. 5911-5920
10 p.
|
artikel
|
| 39 |
Synthesis and structure–activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta
|
Yonekubo, Shigeru
|
|
2016
|
24 |
22 |
p. 5895-5910
16 p.
|
artikel
|
| 40 |
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones
|
Jeon, Kyung-Hwa
|
|
2016
|
24 |
22 |
p. 5921-5928
8 p.
|
artikel
|
| 41 |
Synthesis of novel tetrazole derivatives and evaluation of their antifungal activity
|
Łukowska-Chojnacka, Edyta
|
|
2016
|
24 |
22 |
p. 6058-6065
8 p.
|
artikel
|
| 42 |
Synthesis, photophysical properties and biological evaluation of β-alkylaminoporphyrin for photodynamic therapy
|
Liao, Ping-Yong
|
|
2016
|
24 |
22 |
p. 6040-6047
8 p.
|
artikel
|
| 43 |
Tautomeric and non-tautomeric N-substituted 2-iminobenzimidazolines as new lead compounds for the design of anti-influenza drugs: An in vitro study
|
Zarubaev, Vladimir V.
|
|
2016
|
24 |
22 |
p. 5796-5803
8 p.
|
artikel
|
| 44 |
Triethylated chromones with substituted naphthalenes as tubulin inhibitors
|
Nakagawa-Goto, Kyoko
|
|
2016
|
24 |
22 |
p. 6048-6057
10 p.
|
artikel
|
| 45 |
Zorbamycin has a different DNA sequence selectivity compared with bleomycin and analogues
|
Chen, Jon K.
|
|
2016
|
24 |
22 |
p. 6094-6101
8 p.
|
artikel
|
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