| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase
|
Gu, Shuang-Xi
|
|
2016
|
24 |
21 |
p. 5007-5016
10 p.
|
artikel
|
| 2 |
Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties
|
Alfadhli, Ayna
|
|
2016
|
24 |
21 |
p. 5618-5625
8 p.
|
artikel
|
| 3 |
A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β
|
Zhao, Li-Ming
|
|
2016
|
24 |
21 |
p. 5400-5409
10 p.
|
artikel
|
| 4 |
An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain
|
Ronsisvalle, Simone
|
|
2016
|
24 |
21 |
p. 5280-5290
11 p.
|
artikel
|
| 5 |
Anti-influenza activity of monoterpene-derived substituted hexahydro-2H-chromenes
|
Patrusheva, Oksana S.
|
|
2016
|
24 |
21 |
p. 5158-5161
4 p.
|
artikel
|
| 6 |
Anti-tubercular activities of 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine analogues endowed with high activity toward non-replicative Mycobacterium tuberculosis
|
Samala, Ganesh
|
|
2016
|
24 |
21 |
p. 5556-5564
9 p.
|
artikel
|
| 7 |
Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity
|
Rak, Aleksandra
|
|
2016
|
24 |
21 |
p. 5582-5591
10 p.
|
artikel
|
| 8 |
Blood–brain barrier permeability of ginkgolide: Comparison of the behavior of PET probes 7α-[18F]fluoro- and 10-O-p-[11C]methylbenzyl ginkgolide B in monkey and rat brains
|
Doi, Hisashi
|
|
2016
|
24 |
21 |
p. 5148-5157
10 p.
|
artikel
|
| 9 |
Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities
|
Richard, Mylène
|
|
2016
|
24 |
21 |
p. 5315-5325
11 p.
|
artikel
|
| 10 |
Convergent 18F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands
|
Petersen, Ida Nymann
|
|
2016
|
24 |
21 |
p. 5353-5356
4 p.
|
artikel
|
| 11 |
Design and synthesis of novel HDAC8 inhibitory 2,5-disubstituted-1,3,4-oxadiazoles containing glycine and alanine hybrids with anti cancer activity
|
Pidugu, Vijaya Rao
|
|
2016
|
24 |
21 |
p. 5611-5617
7 p.
|
artikel
|
| 12 |
Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C
|
Carpenter, Colleen
|
|
2016
|
24 |
21 |
p. 5495-5504
10 p.
|
artikel
|
| 13 |
Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4
|
Yang, Yilei
|
|
2016
|
24 |
21 |
p. 5393-5399
7 p.
|
artikel
|
| 14 |
Design, synthesis, and structure–activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element
|
Wang, Yong
|
|
2016
|
24 |
21 |
p. 5646-5661
16 p.
|
artikel
|
| 15 |
Design, synthesis, crystal structure, biological evaluation and molecular docking studies of carbazole-arylpiperazine derivatives
|
Xu, Wei
|
|
2016
|
24 |
21 |
p. 5565-5572
8 p.
|
artikel
|
| 16 |
Development of acetophenone ligands as potential neuroimaging agents for cholinesterases
|
Jollymore-Hughes, Courtney T.
|
|
2016
|
24 |
21 |
p. 5270-5279
10 p.
|
artikel
|
| 17 |
Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure–activity relationships and fluorescence properties
|
Kinoshita, Marie
|
|
2016
|
24 |
21 |
p. 5602-5610
9 p.
|
artikel
|
| 18 |
Development, synthesis and structure–activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei
|
Seufert, Florian
|
|
2016
|
24 |
21 |
p. 5134-5147
14 p.
|
artikel
|
| 19 |
Discovery and structure–activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents
|
Kwak, Seung-Hwa
|
|
2016
|
24 |
21 |
p. 5357-5367
11 p.
|
artikel
|
| 20 |
Discovery of novel free fatty acid receptor 1 agonists bearing triazole core via click chemistry
|
Li, Zheng
|
|
2016
|
24 |
21 |
p. 5449-5454
6 p.
|
artikel
|
| 21 |
Discovery of N-(1-(3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl)ethyl)acetamides as novel acetyl-CoA carboxylase 2 (ACC2) inhibitors with peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonistic activity
|
Okazaki, Shogo
|
|
2016
|
24 |
21 |
p. 5258-5269
12 p.
|
artikel
|
| 22 |
Discovery of O 6-benzyl glaziovianin A, a potent cytotoxic substance and a potent inhibitor of α,β-tubulin polymerization
|
Hayakawa, Ichiro
|
|
2016
|
24 |
21 |
p. 5639-5645
7 p.
|
artikel
|
| 23 |
Editorial board
|
|
|
2016
|
24 |
21 |
p. IFC-
1 p.
|
artikel
|
| 24 |
Effect of lysine methylation and acetylation on the RNA recognition and cellular uptake of Tat-derived peptides
|
Liu, Mu-Chun
|
|
2016
|
24 |
21 |
p. 5047-5051
5 p.
|
artikel
|
| 25 |
Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents
|
Song, Lijun
|
|
2016
|
24 |
21 |
p. 5172-5182
11 p.
|
artikel
|
| 26 |
Expedient synthesis of an atypical oxazolidinone compound library
|
Cully, Sarah J.
|
|
2016
|
24 |
21 |
p. 5249-5257
9 p.
|
artikel
|
| 27 |
Exploration of substituted arylpiperazine–tetrazoles as promising dual norepinephrine and dopamine reuptake inhibitors
|
Paudel, Suresh
|
|
2016
|
24 |
21 |
p. 5546-5555
10 p.
|
artikel
|
| 28 |
Focused screening to identify new adenosine kinase inhibitors
|
Köse, Meryem
|
|
2016
|
24 |
21 |
p. 5127-5133
7 p.
|
artikel
|
| 29 |
Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835
|
Krasavin, Mikhail
|
|
2016
|
24 |
21 |
p. 5481-5494
14 p.
|
artikel
|
| 30 |
Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency
|
Armstrong, Michelle
|
|
2016
|
24 |
21 |
p. 5380-5387
8 p.
|
artikel
|
| 31 |
Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents
|
Li, Yangmei
|
|
2016
|
24 |
21 |
p. 5633-5638
6 p.
|
artikel
|
| 32 |
Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2
|
Keček Plešec, Kaja
|
|
2016
|
24 |
21 |
p. 5221-5234
14 p.
|
artikel
|
| 33 |
In silico and in vitro methods to identify ebola virus VP35-dsRNA inhibitors
|
Glanzer, Jason G.
|
|
2016
|
24 |
21 |
p. 5388-5392
5 p.
|
artikel
|
| 34 |
Investigation of C-5 alkynyl (alkynyloxy or hydroxymethyl) and/or N-3 propynyl substituted pyrimidine nucleoside analogs as a new class of antimicrobial agents
|
Garg, Saurabh
|
|
2016
|
24 |
21 |
p. 5521-5533
13 p.
|
artikel
|
| 35 |
In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification
|
Żołnierczyk, Jolanta D.
|
|
2016
|
24 |
21 |
p. 5076-5087
12 p.
|
artikel
|
| 36 |
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of α-glucosidase
|
Özil, Musa
|
|
2016
|
24 |
21 |
p. 5103-5114
12 p.
|
artikel
|
| 37 |
Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents
|
Ziemska, Joanna
|
|
2016
|
24 |
21 |
p. 5302-5314
13 p.
|
artikel
|
| 38 |
New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties
|
Khomenko, Tatyana
|
|
2016
|
24 |
21 |
p. 5573-5581
9 p.
|
artikel
|
| 39 |
New potently bioactive alkaloids from Crinum erubescens
|
Presley, Christopher C.
|
|
2016
|
24 |
21 |
p. 5418-5422
5 p.
|
artikel
|
| 40 |
Novel multifunctional dopamine D2/D3 receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties
|
Luo, Dan
|
|
2016
|
24 |
21 |
p. 5088-5102
15 p.
|
artikel
|
| 41 |
Optimization and biological evaluation of celastrol derivatives as Hsp90–Cdc37 interaction disruptors with improved druglike properties
|
Jiang, Fen
|
|
2016
|
24 |
21 |
p. 5431-5439
9 p.
|
artikel
|
| 42 |
Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability
|
Chevalier, Arnaud
|
|
2016
|
24 |
21 |
p. 5206-5220
15 p.
|
artikel
|
| 43 |
Phosphonate-based irreversible inhibitors of human γ-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity
|
Kamiyama, Akane
|
|
2016
|
24 |
21 |
p. 5340-5352
13 p.
|
artikel
|
| 44 |
Phosphorothioate analogs of P1,P3-di(nucleosid-5′-yl) triphosphates: Synthesis, assignment of the absolute configuration at P-atoms and P-stereodependent recognition by Fhit hydrolase
|
Kaczmarek, Renata
|
|
2016
|
24 |
21 |
p. 5068-5075
8 p.
|
artikel
|
| 45 |
Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors
|
Pissarnitski, Dmitri A.
|
|
2016
|
24 |
21 |
p. 5534-5545
12 p.
|
artikel
|
| 46 |
Sterol-dependent membrane association of the marine sponge-derived bicyclic peptide Theonellamide A as examined by 1H NMR
|
Cornelio, Kimberly
|
|
2016
|
24 |
21 |
p. 5235-5242
8 p.
|
artikel
|
| 47 |
Structure–activity relationship studies of non-carboxylic acid peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonists
|
Okazaki, Shogo
|
|
2016
|
24 |
21 |
p. 5455-5461
7 p.
|
artikel
|
| 48 |
8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors
|
Brunschweiger, Andreas
|
|
2016
|
24 |
21 |
p. 5462-5480
19 p.
|
artikel
|
| 49 |
Synthesis and activity evaluation of the cyclic dipeptides arylidene N-alkoxydiketopiperazines
|
Tian, Xia
|
|
2016
|
24 |
21 |
p. 5197-5205
9 p.
|
artikel
|
| 50 |
Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo
|
Niu, Chao
|
|
2016
|
24 |
21 |
p. 5440-5448
9 p.
|
artikel
|
| 51 |
Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors
|
Song, Zhendong
|
|
2016
|
24 |
21 |
p. 5505-5512
8 p.
|
artikel
|
| 52 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents
|
Sola, Irene
|
|
2016
|
24 |
21 |
p. 5162-5171
10 p.
|
artikel
|
| 53 |
Synthesis and biological evaluation of novel hydrogen sulfide releasing nicotinic acid derivatives
|
Sun, Yinxing
|
|
2016
|
24 |
21 |
p. 5368-5373
6 p.
|
artikel
|
| 54 |
Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity
|
Gromek, Samantha M.
|
|
2016
|
24 |
21 |
p. 5183-5196
14 p.
|
artikel
|
| 55 |
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors
|
Gaines, Theresa
|
|
2016
|
24 |
21 |
p. 5052-5060
9 p.
|
artikel
|
| 56 |
Synthesis and evaluation of 6-pyrazoylamido-3N-substituted azabicyclo[3,1,0]hexane derivatives as T-type calcium channel inhibitors for treatment of neuropathic pain
|
Kim, Jung Hyun
|
|
2016
|
24 |
21 |
p. 5028-5035
8 p.
|
artikel
|
| 57 |
Synthesis and preclinical characterization of 1-(6′-deoxy-6′-[18F]fluoro-β-d-allofuranosyl)-2-nitroimidazole (β-6′-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia
|
Wanek, Thomas
|
|
2016
|
24 |
21 |
p. 5326-5339
14 p.
|
artikel
|
| 58 |
Synthesis, biological evaluation and molecular docking study of N-arylbenzo[d]oxazol-2-amines as potential α-glucosidase inhibitors
|
Wang, Guangcheng
|
|
2016
|
24 |
21 |
p. 5374-5379
6 p.
|
artikel
|
| 59 |
Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor
|
Zeyrek, Celal Tuğrul
|
|
2016
|
24 |
21 |
p. 5592-5601
10 p.
|
artikel
|
| 60 |
Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB2 receptor antagonists/inverse agonists
|
Dore, Antonio
|
|
2016
|
24 |
21 |
p. 5291-5301
11 p.
|
artikel
|
| 61 |
Synthesis of arylated coumarins by Suzuki–Miyaura cross-coupling. Reactions and anti-HIV activity
|
Hamdy, Aws M.
|
|
2016
|
24 |
21 |
p. 5115-5126
12 p.
|
artikel
|
| 62 |
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors
|
Galal, Shadia A.
|
|
2016
|
24 |
21 |
p. 5423-5430
8 p.
|
artikel
|
| 63 |
Synthesis of phenylpiperazine derivatives of 1,4-benzodioxan as selective COX-2 inhibitors and anti-inflammatory agents
|
Sun, Juan
|
|
2016
|
24 |
21 |
p. 5626-5632
7 p.
|
artikel
|
| 64 |
The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3
|
Lee, Sun-Mi
|
|
2016
|
24 |
21 |
p. 5036-5046
11 p.
|
artikel
|
| 65 |
Thermodynamic properties of leukotriene A4 hydrolase inhibitors
|
Wittmann, Sandra K.
|
|
2016
|
24 |
21 |
p. 5243-5248
6 p.
|
artikel
|
| 66 |
Thioflavones as novel neuroprotective agents
|
Ravishankar, Divyashree
|
|
2016
|
24 |
21 |
p. 5513-5520
8 p.
|
artikel
|
| 67 |
1,2,3-Triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation
|
Patil, Pravin C.
|
|
2016
|
24 |
21 |
p. 5410-5417
8 p.
|
artikel
|
| 68 |
Triterpenoids from Momordica balsamina: Reversal of ABCB1-mediated multidrug resistance
|
Ramalhete, Cátia
|
|
2016
|
24 |
21 |
p. 5061-5067
7 p.
|
artikel
|
| 69 |
Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential
|
Laev, Sergey S.
|
|
2016
|
24 |
21 |
p. 5017-5027
11 p.
|
artikel
|
Tijdschrift beschrijving