| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A new motif for inhibitors of geranylgeranyl diphosphate synthase
|
Foust, Benjamin J.
|
|
2016
|
24 |
16 |
p. 3734-3741
8 p.
|
artikel
|
| 2 |
An expeditious four-component domino protocol for the synthesis of novel thiazolo[3,2-a]thiochromeno[4,3-d]pyrimidine derivatives as antibacterial and antibiofilm agents
|
Suresh, Lingala
|
|
2016
|
24 |
16 |
p. 3808-3817
10 p.
|
artikel
|
| 3 |
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae
|
Del Prete, Sonia
|
|
2016
|
24 |
16 |
p. 3413-3417
5 p.
|
artikel
|
| 4 |
Antiprotozoal activity of bicycles featuring a dimethylamino group at their bridgehead
|
Faist, Johanna
|
|
2016
|
24 |
16 |
p. 3781-3789
9 p.
|
artikel
|
| 5 |
Arabinoamidine synthesis and its inhibition toward β-glucosidase (sweet almonds) in comparison to a library of galactonoamidines
|
Pickens, Jessica B.
|
|
2016
|
24 |
16 |
p. 3371-3377
7 p.
|
artikel
|
| 6 |
A sulfanyl-PEG derivative of relaxin-like peptide utilizable for the conjugation with KLH and the antibody production
|
Katayama, Hidekazu
|
|
2016
|
24 |
16 |
p. 3596-3602
7 p.
|
artikel
|
| 7 |
Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction
|
Khan, Firoz A. Kalam
|
|
2016
|
24 |
16 |
p. 3456-3463
8 p.
|
artikel
|
| 8 |
2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase
|
Leong, Sze Wei
|
|
2016
|
24 |
16 |
p. 3742-3751
10 p.
|
artikel
|
| 9 |
Bistacrine derivatives as new potent antimalarials
|
Schmidt, Ines
|
|
2016
|
24 |
16 |
p. 3636-3642
7 p.
|
artikel
|
| 10 |
Combined dual effect of modulation of human neutrophils’ oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives
|
Tavares-da-Silva, Elisiário J.
|
|
2016
|
24 |
16 |
p. 3556-3564
9 p.
|
artikel
|
| 11 |
Cyclopamine bioactivity by extraction method from Veratrum californicum
|
Turner, Matthew W.
|
|
2016
|
24 |
16 |
p. 3752-3757
6 p.
|
artikel
|
| 12 |
Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands
|
Ofori, Edward
|
|
2016
|
24 |
16 |
p. 3464-3471
8 p.
|
artikel
|
| 13 |
Design and synthesis of potent and selective pyridazin-4(1H)-one-based PDE10A inhibitors interacting with Tyr683 in the PDE10A selectivity pocket
|
Yoshikawa, Masato
|
|
2016
|
24 |
16 |
p. 3447-3455
9 p.
|
artikel
|
| 14 |
Design, synthesis, and anticancer activity of C8-substituted-4′-thionucleosides as potential HSP90 inhibitors
|
Qu, Shuhao
|
|
2016
|
24 |
16 |
p. 3418-3428
11 p.
|
artikel
|
| 15 |
Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2
|
Qiang, Hao
|
|
2016
|
24 |
16 |
p. 3353-3358
6 p.
|
artikel
|
| 16 |
Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors – Part 3
|
Yukawa, Tomoya
|
|
2016
|
24 |
16 |
p. 3716-3726
11 p.
|
artikel
|
| 17 |
Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-β-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer’s disease
|
Mishra, Chandra Bhushan
|
|
2016
|
24 |
16 |
p. 3829-3841
13 p.
|
artikel
|
| 18 |
Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres
|
Kormos, Chad M.
|
|
2016
|
24 |
16 |
p. 3842-3848
7 p.
|
artikel
|
| 19 |
Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies
|
Abdel-Aziz, Alaa A.-M.
|
|
2016
|
24 |
16 |
p. 3818-3828
11 p.
|
artikel
|
| 20 |
Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores
|
Etukala, Jagan R.
|
|
2016
|
24 |
16 |
p. 3671-3679
9 p.
|
artikel
|
| 21 |
Development of novel NK3 receptor antagonists with reduced environmental impact
|
Yamamoto, Koki
|
|
2016
|
24 |
16 |
p. 3494-3500
7 p.
|
artikel
|
| 22 |
Dihydropyrimidones: As novel class of β-glucuronidase inhibitors
|
Ali, Farman
|
|
2016
|
24 |
16 |
p. 3624-3635
12 p.
|
artikel
|
| 23 |
Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist
|
Koura, Minoru
|
|
2016
|
24 |
16 |
p. 3436-3446
11 p.
|
artikel
|
| 24 |
Discovery of a novel small molecule agonist scaffold for the APJ receptor
|
Narayanan, Sanju
|
|
2016
|
24 |
16 |
p. 3758-3770
13 p.
|
artikel
|
| 25 |
Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition
|
Sweeney, Martin
|
|
2016
|
24 |
16 |
p. 3565-3570
6 p.
|
artikel
|
| 26 |
Discovery of 3-benzyl-1,3-benzoxazine-2,4-dione analogues as allosteric mitogen-activated kinase kinase (MEK) inhibitors and anti-enterovirus 71 (EV71) agents
|
Sun, Jing
|
|
2016
|
24 |
16 |
p. 3472-3482
11 p.
|
artikel
|
| 27 |
Doxifluridine-conjugated 2-5A analog shows strong RNase L activation ability and tumor suppressive effect
|
Kitamura, Yoshiaki
|
|
2016
|
24 |
16 |
p. 3870-3874
5 p.
|
artikel
|
| 28 |
Editorial board
|
|
|
2016
|
24 |
16 |
p. IFC-
1 p.
|
artikel
|
| 29 |
Effects of 8-halo-7-deaza-2′-deoxyguanosine triphosphate on DNA synthesis by DNA polymerases and cell proliferation
|
Yin, Yizhen
|
|
2016
|
24 |
16 |
p. 3856-3861
6 p.
|
artikel
|
| 30 |
Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization
|
Toyama, Kei
|
|
2016
|
24 |
16 |
p. 3406-3412
7 p.
|
artikel
|
| 31 |
Hydrophobic substituents increase the potency of salacinol, a potent α-glucosidase inhibitor from Ayurvedic traditional medicine ‘Salacia’
|
Tanabe, Genzoh
|
|
2016
|
24 |
16 |
p. 3705-3715
11 p.
|
artikel
|
| 32 |
Identification of a novel boronic acid as a potent, selective, and orally active hormone sensitive lipase inhibitor
|
Ogiyama, Tomoko
|
|
2016
|
24 |
16 |
p. 3801-3807
7 p.
|
artikel
|
| 33 |
Identification of anticancer agents based on the thieno[2,3-b]pyridine and 1H-pyrazole molecular scaffolds
|
Eurtivong, Chatchakorn
|
|
2016
|
24 |
16 |
p. 3521-3526
6 p.
|
artikel
|
| 34 |
Ionophoric polyphenols selectively bind Cu2+, display potent antioxidant and anti-amyloidogenic properties, and are non-toxic toward Tetrahymena thermophila
|
Martínez, Alberto
|
|
2016
|
24 |
16 |
p. 3657-3670
14 p.
|
artikel
|
| 35 |
Isomeric iodinated analogs of nimesulide: Synthesis, physicochemical characterization, cyclooxygenase-2 inhibitory activity, and transport across Caco-2 cells
|
Yamamoto, Yumi
|
|
2016
|
24 |
16 |
p. 3727-3733
7 p.
|
artikel
|
| 36 |
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine–benzenesulfonamides acting as carbonic anhydrase inhibitors
|
Vullo, Daniela
|
|
2016
|
24 |
16 |
p. 3643-3648
6 p.
|
artikel
|
| 37 |
Microwave assisted synthesis of novel acridine–acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII
|
Ulus, Ramazan
|
|
2016
|
24 |
16 |
p. 3548-3555
8 p.
|
artikel
|
| 38 |
Molecular similarity guided optimization of novel Nrf2 activators with 1,2,4-oxadiazole core
|
Xu, Li-Li
|
|
2016
|
24 |
16 |
p. 3540-3547
8 p.
|
artikel
|
| 39 |
N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition
|
Nocentini, Alessio
|
|
2016
|
24 |
16 |
p. 3612-3617
6 p.
|
artikel
|
| 40 |
Novel benzimidazol-2-ylidene carbene precursors and their silver(I) complexes: Potential antimicrobial agents
|
Kaloğlu, Murat
|
|
2016
|
24 |
16 |
p. 3649-3656
8 p.
|
artikel
|
| 41 |
Novel drug design for Chagas disease via targeting Trypanosoma cruzi tubulin: Homology modeling and binding pocket prediction on Trypanosoma cruzi tubulin polymerization inhibition by naphthoquinone derivatives
|
Ogindo, Charles O.
|
|
2016
|
24 |
16 |
p. 3849-3855
7 p.
|
artikel
|
| 42 |
6-Oxooxazolidine–quinazolines as noncovalent inhibitors with the potential to target mutant forms of EGFR
|
Shao, Jiaan
|
|
2016
|
24 |
16 |
p. 3359-3370
12 p.
|
artikel
|
| 43 |
Proteasome inhibition by new dual warhead containing peptido vinyl sulfonyl fluorides
|
Brouwer, Arwin J.
|
|
2016
|
24 |
16 |
p. 3429-3435
7 p.
|
artikel
|
| 44 |
Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface
|
Bhakkiyalakshmi, Elango
|
|
2016
|
24 |
16 |
p. 3378-3386
9 p.
|
artikel
|
| 45 |
Sequence-specific DNA binding by long hairpin pyrrole–imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit
|
Sawatani, Yoshito
|
|
2016
|
24 |
16 |
p. 3603-3611
9 p.
|
artikel
|
| 46 |
5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms
|
Orban, Oliver C.F.
|
|
2016
|
24 |
16 |
p. 3790-3800
11 p.
|
artikel
|
| 47 |
Synthesis and anticancer activity of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives bearing chromone moiety
|
Sun, Chengyu
|
|
2016
|
24 |
16 |
p. 3862-3869
8 p.
|
artikel
|
| 48 |
Synthesis and biological evaluation of new [1,2,4]triazolo[4,3-a]pyridine derivatives as potential c-Met inhibitors
|
Zhao, Junjun
|
|
2016
|
24 |
16 |
p. 3483-3493
11 p.
|
artikel
|
| 49 |
Synthesis and biological evaluation of novel N-arylidenequinoline-3-carbohydrazides as potent β-glucuronidase inhibitors
|
Taha, Muhammad
|
|
2016
|
24 |
16 |
p. 3696-3704
9 p.
|
artikel
|
| 50 |
Synthesis and evaluation of antioxidant phenolic diaryl hydrazones as potent antiangiogenic agents in atherosclerosis
|
Vanucci-Bacqué, Corinne
|
|
2016
|
24 |
16 |
p. 3571-3578
8 p.
|
artikel
|
| 51 |
Synthesis and evaluation of antitubercular activity of fluorinated 5-aryl-4-(hetero)aryl substituted pyrimidines
|
Verbitskiy, Egor V.
|
|
2016
|
24 |
16 |
p. 3771-3780
10 p.
|
artikel
|
| 52 |
Synthesis and evaluation of copper-64 labeled benzofuran derivatives targeting β-amyloid aggregates
|
Watanabe, Hiroyuki
|
|
2016
|
24 |
16 |
p. 3618-3623
6 p.
|
artikel
|
| 53 |
Synthesis and investigation of novel benzimidazole derivatives as antifungal agents
|
Chandrika, Nishad Thamban
|
|
2016
|
24 |
16 |
p. 3680-3686
7 p.
|
artikel
|
| 54 |
Synthesis and in vitro α-chymotrypsin inhibitory activity of 6-chlorobenzimidazole derivatives
|
Siddiqui, Hina
|
|
2016
|
24 |
16 |
p. 3387-3395
9 p.
|
artikel
|
| 55 |
Synthesis and Th1-immunostimulatory activity of α-galactosylceramide analogues bearing a halogen-containing or selenium-containing acyl chain
|
Hossain, Md. Imran
|
|
2016
|
24 |
16 |
p. 3687-3695
9 p.
|
artikel
|
| 56 |
Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates
|
Faidallah, Hassan M.
|
|
2016
|
24 |
16 |
p. 3527-3539
13 p.
|
artikel
|
| 57 |
Synthesis, photophysical properties of triazolyl-donor/acceptor chromophores decorated unnatural amino acids: Incorporation of a pair into Leu-enkephalin peptide and application of triazolylperylene amino acid in sensing BSA
|
Bag, Subhendu Sekhar
|
|
2016
|
24 |
16 |
p. 3579-3595
17 p.
|
artikel
|
| 58 |
Synthetic sulfoglycolipids targeting the serine–threonine protein kinase Akt
|
Costa, Barbara
|
|
2016
|
24 |
16 |
p. 3396-3405
10 p.
|
artikel
|
| 59 |
Systematic N-methylation of oxytocin: Impact on pharmacology and intramolecular hydrogen bonding network
|
Sciabola, Simone
|
|
2016
|
24 |
16 |
p. 3513-3520
8 p.
|
artikel
|
| 60 |
The design strategy of selective PTP1B inhibitors over TCPTP
|
Li, XiangQian
|
|
2016
|
24 |
16 |
p. 3343-3352
10 p.
|
artikel
|
| 61 |
Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives
|
Mowafy, Samar
|
|
2016
|
24 |
16 |
p. 3501-3512
12 p.
|
artikel
|
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