| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Addition of niclosamide to palladium(II) saccharinate complex of terpyridine results in enhanced cytotoxic activity inducing apoptosis on cancer stem cells of breast cancer
|
Karakas, Didem
|
|
2015
|
23 |
17 |
p. 5580-5586
7 p.
|
artikel
|
| 2 |
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties
|
Liu, Chong
|
|
2015
|
23 |
17 |
p. 5496-5501
6 p.
|
artikel
|
| 3 |
A new small molecule inhibitor of soluble guanylate cyclase
|
Mota , Filipa
|
|
2015
|
23 |
17 |
p. 5303-5310
8 p.
|
artikel
|
| 4 |
Anti-inflammatory and antiproliferative evaluation of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivatives
|
Dalla Via, L.
|
|
2015
|
23 |
17 |
p. 5816-5828
13 p.
|
artikel
|
| 5 |
Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferases
|
Hocková, Dana
|
|
2015
|
23 |
17 |
p. 5502-5510
9 p.
|
artikel
|
| 6 |
Antimalarial benzoheterocyclic 4-aminoquinolines: Structure–activity relationship, in vivo evaluation, mechanistic and bioactivation studies
|
Ongarora, Dennis S.B.
|
|
2015
|
23 |
17 |
p. 5419-5432
14 p.
|
artikel
|
| 7 |
Anti-Plasmodium falciparum activity of quinoline–sulfonamide hybrids
|
Pinheiro, Luiz C.S.
|
|
2015
|
23 |
17 |
p. 5979-5984
6 p.
|
artikel
|
| 8 |
Antiproliferative and apoptosis-inducing activities of novel naphthalimide–cyclam conjugates through dual topoisomerase (topo) I/II inhibition
|
Tan , Shaoying
|
|
2015
|
23 |
17 |
p. 5672-5680
9 p.
|
artikel
|
| 9 |
A P450 fusion library of heme domains from Rhodococcus jostii RHA1 and its evaluation for the biotransformation of drug molecules
|
Kulig, Justyna K.
|
|
2015
|
23 |
17 |
p. 5603-5609
7 p.
|
artikel
|
| 10 |
A-ring substituted 17β-arylsulfonamides of 17β-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase
|
Mostafa, Yaser A.
|
|
2015
|
23 |
17 |
p. 5681-5692
12 p.
|
artikel
|
| 11 |
Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses
|
Botta, Giorgia
|
|
2015
|
23 |
17 |
p. 5345-5351
7 p.
|
artikel
|
| 12 |
Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels
|
Lu, Jianyu
|
|
2015
|
23 |
17 |
p. 5985-5998
14 p.
|
artikel
|
| 13 |
Chemoenzymatic synthesis and cytotoxicity of oenanthotoxin and analogues
|
Sommerwerk , Sven
|
|
2015
|
23 |
17 |
p. 5595-5602
8 p.
|
artikel
|
| 14 |
Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A
|
Teng, Yu-Han Gary
|
|
2015
|
23 |
17 |
p. 5489-5495
7 p.
|
artikel
|
| 15 |
Corrigendum to “Discovery and structural analyses of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogs” [Bioorg. Med. Chem. 23 (2015) 4952–4969]
|
Nakao, Akira
|
|
2015
|
23 |
17 |
p. 6078-
1 p.
|
artikel
|
| 16 |
Corrigendum to “Discovery of novel tetrahydroisoquinoline derivatives as orally active N-type calcium channel blockers with high selectivity for hERG potassium channels” [Bioorg. Med. Chem. 22 (2014) 6899–6907]
|
Ogiyama, Takashi
|
|
2015
|
23 |
17 |
p. 6079-
1 p.
|
artikel
|
| 17 |
Cyclen-based double-tailed lipids for DNA delivery: Synthesis and the effect of linking group structures
|
Zhang , Yi-Mei
|
|
2015
|
23 |
17 |
p. 5756-5763
8 p.
|
artikel
|
| 18 |
Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability
|
Kamal, Ahmed
|
|
2015
|
23 |
17 |
p. 5511-5526
16 p.
|
artikel
|
| 19 |
Design and synthesis of new barbituric- and thiobarbituric acid derivatives as potent urease inhibitors: Structure activity relationship and molecular modeling studies
|
Rauf, Abdul
|
|
2015
|
23 |
17 |
p. 6049-6058
10 p.
|
artikel
|
| 20 |
Design and synthesis of new non nucleoside inhibitors of DNMT3A
|
Erdmann, Alexandre
|
|
2015
|
23 |
17 |
p. 5946-5953
8 p.
|
artikel
|
| 21 |
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3
|
Djigoué, Guy Bertrand
|
|
2015
|
23 |
17 |
p. 5433-5451
19 p.
|
artikel
|
| 22 |
Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors
|
Yang, Wei
|
|
2015
|
23 |
17 |
p. 5881-5890
10 p.
|
artikel
|
| 23 |
Design, synthesis and biological evaluation of saccharin-based N-hydroxybenzamides as histone deacetylases (HDACs) inhibitors
|
Fu, Huansheng
|
|
2015
|
23 |
17 |
p. 5774-5781
8 p.
|
artikel
|
| 24 |
Design, synthesis and cytotoxicity studies of dithiocarbamate ester derivatives of emetine in prostate cancer cell lines
|
Akinboye, Emmanuel S.
|
|
2015
|
23 |
17 |
p. 5839-5845
7 p.
|
artikel
|
| 25 |
Design, synthesis and immunological evaluation of 1,2,3-triazole-tethered carbohydrate–Pam3Cys conjugates as TLR2 agonists
|
Nalla, Naresh
|
|
2015
|
23 |
17 |
p. 5846-5855
10 p.
|
artikel
|
| 26 |
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET radiotracers
|
Ebert, Kristin
|
|
2015
|
23 |
17 |
p. 6025-6035
11 p.
|
artikel
|
| 27 |
Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1
|
Lazarus, Michael B.
|
|
2015
|
23 |
17 |
p. 5483-5488
6 p.
|
artikel
|
| 28 |
Discovery of a series of novel compounds with moderate anti-hepatitis C virus NS3 protease activity in vitro
|
Shi, Fangyuan
|
|
2015
|
23 |
17 |
p. 5539-5545
7 p.
|
artikel
|
| 29 |
Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonists
|
Wang, Yonghui
|
|
2015
|
23 |
17 |
p. 5293-5302
10 p.
|
artikel
|
| 30 |
Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton’s tyrosine kinase (BTK) inhibitors
|
Zhao, Xinge
|
|
2015
|
23 |
17 |
p. 6059-6068
10 p.
|
artikel
|
| 31 |
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells
|
Okolotowicz, Karl J.
|
|
2015
|
23 |
17 |
p. 5282-5292
11 p.
|
artikel
|
| 32 |
Dual inhibitors of the dengue and West Nile virus NS2B–NS3 proteases: Synthesis, biological evaluation and docking studies of novel peptide-hybrids
|
Bastos Lima, Allan
|
|
2015
|
23 |
17 |
p. 5748-5755
8 p.
|
artikel
|
| 33 |
Editorial board
|
|
|
2015
|
23 |
17 |
p. IFC-
1 p.
|
artikel
|
| 34 |
Efficient one-pot synthesis of CXCL14 and its derivative using an N-sulfanylethylanilide peptide as a peptide thioester equivalent and their biological evaluation
|
Tsuji , Kohei
|
|
2015
|
23 |
17 |
p. 5909-5914
6 p.
|
artikel
|
| 35 |
Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine
|
Del Bello , Fabio
|
|
2015
|
23 |
17 |
p. 5574-5579
6 p.
|
artikel
|
| 36 |
Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
|
Hattori, Yasunao
|
|
2015
|
23 |
17 |
p. 5626-5640
15 p.
|
artikel
|
| 37 |
Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
|
Paine, Helen A.
|
|
2015
|
23 |
17 |
p. 5891-5908
18 p.
|
artikel
|
| 38 |
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies
|
Mollica, Adriano
|
|
2015
|
23 |
17 |
p. 5311-5318
8 p.
|
artikel
|
| 39 |
Factors that influence T box riboswitch efficacy and tRNA affinity
|
Zeng, C.
|
|
2015
|
23 |
17 |
p. 5702-5708
7 p.
|
artikel
|
| 40 |
Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity
|
Atanasova, Mariyana
|
|
2015
|
23 |
17 |
p. 5382-5389
8 p.
|
artikel
|
| 41 |
Graphical contents list
|
|
|
2015
|
23 |
17 |
p. 5225-5246
22 p.
|
artikel
|
| 42 |
Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluations
|
Massimba-Dibama, Hugues
|
|
2015
|
23 |
17 |
p. 5410-5418
9 p.
|
artikel
|
| 43 |
Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy
|
Lounsbury, Nicole
|
|
2015
|
23 |
17 |
p. 5352-5359
8 p.
|
artikel
|
| 44 |
Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities
|
Reiter, Christoph
|
|
2015
|
23 |
17 |
p. 5452-5458
7 p.
|
artikel
|
| 45 |
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathway
|
Del Bello , Fabio
|
|
2015
|
23 |
17 |
p. 5725-5733
9 p.
|
artikel
|
| 46 |
Identification of 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (29) as an orally available MGAT2 inhibitor
|
Busujima, Tsuyoshi
|
|
2015
|
23 |
17 |
p. 5922-5931
10 p.
|
artikel
|
| 47 |
Imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibition
|
Negi, Arvind
|
|
2015
|
23 |
17 |
p. 5654-5661
8 p.
|
artikel
|
| 48 |
Instructions to contributors
|
|
|
2015
|
23 |
17 |
p. I-
1 p.
|
artikel
|
| 49 |
Metabolically programmed iron chelators
|
Bergeron, Raymond J.
|
|
2015
|
23 |
17 |
p. 5954-5971
18 p.
|
artikel
|
| 50 |
Modification of N-(6-(2-methoxy-3-(4-fluorophenylsulfonamido)pyridin-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide as PI3Ks inhibitor by replacement of the acetamide group with alkylurea
|
Wang, Xiao-Meng
|
|
2015
|
23 |
17 |
p. 5662-5671
10 p.
|
artikel
|
| 51 |
Molecular dynamics and density functional studies on the metabolic selectivity of antipsychotic thioridazine by cytochrome P450 2D6: Connection with crystallographic and metabolic results
|
Sasahara, Katsunori
|
|
2015
|
23 |
17 |
p. 5459-5465
7 p.
|
artikel
|
| 52 |
New acyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregation
|
Mohamed , Heba A.H.
|
|
2015
|
23 |
17 |
p. 6069-6077
9 p.
|
artikel
|
| 53 |
NMR-based conformational analysis of 2′,6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs
|
da Paixão Soares, Fábio
|
|
2015
|
23 |
17 |
p. 5809-5815
7 p.
|
artikel
|
| 54 |
Novel diazabicycloalkane delta opioid agonists
|
Loriga, Giovanni
|
|
2015
|
23 |
17 |
p. 5527-5538
12 p.
|
artikel
|
| 55 |
Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis
|
Waldmann, Christopher M.
|
|
2015
|
23 |
17 |
p. 5734-5739
6 p.
|
artikel
|
| 56 |
Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine–pyridine–histidine system
|
Ali , Taha F.S.
|
|
2015
|
23 |
17 |
p. 5476-5482
7 p.
|
artikel
|
| 57 |
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558
|
Takano , Rieko
|
|
2015
|
23 |
17 |
p. 5546-5565
20 p.
|
artikel
|
| 58 |
Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitors
|
Wang, Sheng-Biao
|
|
2015
|
23 |
17 |
p. 5740-5747
8 p.
|
artikel
|
| 59 |
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors
|
Wang, Zhen
|
|
2015
|
23 |
17 |
p. 5566-5573
8 p.
|
artikel
|
| 60 |
Phosphate-modified analogues of m7GTP and m7Gppppm7G—Synthesis and biochemical properties
|
Ziemniak, Marcin
|
|
2015
|
23 |
17 |
p. 5369-5381
13 p.
|
artikel
|
| 61 |
Photoaffinity labeling studies of the carbohydrate-binding proteins with different affinities
|
Sakurai, Kaori
|
|
2015
|
23 |
17 |
p. 5319-5325
7 p.
|
artikel
|
| 62 |
Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase
|
Patel, Rahul V.
|
|
2015
|
23 |
17 |
p. 5247-5263
17 p.
|
artikel
|
| 63 |
Radiosynthesis of 4-[18F]fluoro-l-tryptophan by isotopic exchange on carbonyl-activated precursors
|
Weiss, Philipp S.
|
|
2015
|
23 |
17 |
p. 5856-5869
14 p.
|
artikel
|
| 64 |
Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting
|
Tran, Thi Phuong Anh
|
|
2015
|
23 |
17 |
p. 5334-5344
11 p.
|
artikel
|
| 65 |
Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane
|
Yamamoto, Tomoya
|
|
2015
|
23 |
17 |
p. 5782-5788
7 p.
|
artikel
|
| 66 |
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase
|
Fudo, Satoshi
|
|
2015
|
23 |
17 |
p. 5466-5475
10 p.
|
artikel
|
| 67 |
Structure–activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure
|
Mook Jr., Robert A.
|
|
2015
|
23 |
17 |
p. 5829-5838
10 p.
|
artikel
|
| 68 |
Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin
|
Roubalová, Lenka
|
|
2015
|
23 |
17 |
p. 5402-5409
8 p.
|
artikel
|
| 69 |
Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compounds
|
Nguyen, Son T.
|
|
2015
|
23 |
17 |
p. 5789-5798
10 p.
|
artikel
|
| 70 |
Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines
|
Nitulescu , George Mihai
|
|
2015
|
23 |
17 |
p. 5799-5808
10 p.
|
artikel
|
| 71 |
Synthesis and biological evaluation of (3′,5′-dichloro-2,6-dihydroxy-biphenyl-4-yl)-aryl/alkyl-methanone selective CB2 inverse agonist
|
Presley, Chaela S.
|
|
2015
|
23 |
17 |
p. 5390-5401
12 p.
|
artikel
|
| 72 |
Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands
|
Prescher, Horst
|
|
2015
|
23 |
17 |
p. 5915-5921
7 p.
|
artikel
|
| 73 |
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties
|
Congiu, Cenzo
|
|
2015
|
23 |
17 |
p. 5619-5625
7 p.
|
artikel
|
| 74 |
Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligands
|
Cao, Yongkai
|
|
2015
|
23 |
17 |
p. 5264-5272
9 p.
|
artikel
|
| 75 |
Synthesis and optical properties of chlorin monomer, dimer and trimer on an amino nitrogen atom
|
Tamiaki, Hitoshi
|
|
2015
|
23 |
17 |
p. 5972-5978
7 p.
|
artikel
|
| 76 |
Synthesis and structure–activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists
|
Meltzer, Diana
|
|
2015
|
23 |
17 |
p. 5764-5773
10 p.
|
artikel
|
| 77 |
Synthesis, binding, nuclease resistance and cellular uptake properties of 2′-O-acetalester-modified oligonucleotides containing cationic groups
|
Biscans, Annabelle
|
|
2015
|
23 |
17 |
p. 5360-5368
9 p.
|
artikel
|
| 78 |
Synthesis, biological evaluation and docking study of maleimide derivatives bearing benzenesulfonamide as selective COX-2 inhibitors and anti-inflammatory agents
|
Firke, Sandip D.
|
|
2015
|
23 |
17 |
p. 5273-5281
9 p.
|
artikel
|
| 79 |
Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease
|
Bajda, Marek
|
|
2015
|
23 |
17 |
p. 5610-5618
9 p.
|
artikel
|
| 80 |
Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase
|
Ashraf , Zaman
|
|
2015
|
23 |
17 |
p. 5870-5880
11 p.
|
artikel
|
| 81 |
Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs
|
Ondachi , Pauline W.
|
|
2015
|
23 |
17 |
p. 5693-5701
9 p.
|
artikel
|
| 82 |
Synthesis of CNS active thyrotropin-releasing hormone (TRH)-like peptides: Biological evaluation and effect on cognitive impairment induced by cerebral ischemia in mice
|
Meena, Chhuttan L.
|
|
2015
|
23 |
17 |
p. 5641-5653
13 p.
|
artikel
|
| 83 |
Synthesis of mouse centromere-targeted polyamides and physico-chemical studies of their interaction with the target double-stranded DNA
|
Nozeret, Karine
|
|
2015
|
23 |
17 |
p. 5932-5945
14 p.
|
artikel
|
| 84 |
Synthesis of novel triazoles and a tetrazole of escitalopram as cholinesterase inhibitors
|
Mehr-un-Nisa ,
|
|
2015
|
23 |
17 |
p. 6014-6024
11 p.
|
artikel
|
| 85 |
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
|
St. John, Sarah E.
|
|
2015
|
23 |
17 |
p. 6036-6048
13 p.
|
artikel
|
| 86 |
The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor
|
Perrey, David A.
|
|
2015
|
23 |
17 |
p. 5709-5724
16 p.
|
artikel
|
| 87 |
The influence of the C5 substituent on the 2-thiouridine desulfuration pathway and the conformational analysis of the resulting 4-pyrimidinone products
|
Bartos, Paulina
|
|
2015
|
23 |
17 |
p. 5587-5594
8 p.
|
artikel
|
| 88 |
Tight binding enantiomers of pre-clinical drug candidates
|
Evans, Gary B.
|
|
2015
|
23 |
17 |
p. 5326-5333
8 p.
|
artikel
|
| 89 |
Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanoma
|
Murph, Mandi M.
|
|
2015
|
23 |
17 |
p. 5999-6013
15 p.
|
artikel
|
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