| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Anti-growth effect of a novel trans-dichloridobis[2-(2-hydroxyethyl)pyridine]platinum (II) complex via induction of apoptosis on breast cancer cell lines
|
Oral, Arzu Yilmaztepe
|
|
|
23 |
15 |
p. 4303-4310
|
artikel
|
| 2 |
Anti-HIV screening for cell-penetrating peptides using chloroquine and identification of anti-HIV peptides derived from matrix proteins
|
Mizuguchi, Takaaki
|
|
|
23 |
15 |
p. 4423-4427
|
artikel
|
| 3 |
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes
|
Lee, Hsueh-Yun
|
|
|
23 |
15 |
p. 4230-4236
|
artikel
|
| 4 |
Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines
|
Temburnikar, Kartik W.
|
|
|
23 |
15 |
p. 4354-4363
|
artikel
|
| 5 |
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII
|
Cvijetić, Ilija N.
|
|
|
23 |
15 |
p. 4649-4659
|
artikel
|
| 6 |
Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2
|
Stroth, Nikolas
|
|
|
23 |
15 |
p. 4824-4830
|
artikel
|
| 7 |
Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH
|
Abdullah, Iskandar
|
|
|
23 |
15 |
p. 4669-4680
|
artikel
|
| 8 |
Benzoic acid derivatives with improved antifungal activity: Design, synthesis, structure–activity relationship (SAR) and CYP53 docking studies
|
Berne, Sabina
|
|
|
23 |
15 |
p. 4264-4276
|
artikel
|
| 9 |
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect
|
Alves, Silmara L.G.
|
|
|
23 |
15 |
p. 4397-4404
|
artikel
|
| 10 |
BN/CC isosterism in borazaronaphthalenes towards phosphodiesterase 10A (PDE10A) inhibitors
|
Vlasceanu, Alexandru
|
|
|
23 |
15 |
p. 4453-4461
|
artikel
|
| 11 |
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis
|
De Luca, Viviana
|
|
|
23 |
15 |
p. 4405-4409
|
artikel
|
| 12 |
Corrigendum to “Discovery of quinazolin-4-amines bearing benzimidazole fragments as dual inhibitors of c-Met and VEGFR-2” [Bioorg. Med. Chem. 22 (2014) 4735–4744]
|
Shi, Lei
|
|
|
23 |
15 |
p. 5076
|
artikel
|
| 13 |
Corrigendum to “Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease” [Bioorg. Med. Chem. 23 (2015) 1102–1111]
|
Dixon, Monica
|
|
|
23 |
15 |
p. 5077
|
artikel
|
| 14 |
Corrigendum to “Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR” [Bioorg. Med. Chem. 23, 2015, 2767–2780]
|
Basu, Debjit
|
|
|
23 |
15 |
p. 5075
|
artikel
|
| 15 |
Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates
|
Fonseca, Emanuella M.B.
|
|
|
23 |
15 |
p. 4462-4471
|
artikel
|
| 16 |
Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors
|
Liao, Weike
|
|
|
23 |
15 |
p. 4410-4422
|
artikel
|
| 17 |
Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis
|
Masaki, So
|
|
|
23 |
15 |
p. 4434-4441
|
artikel
|
| 18 |
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII
|
Ibrahim, Diaa A.
|
|
|
23 |
15 |
p. 4989-4999
|
artikel
|
| 19 |
Design, synthesis and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitor
|
Fujimori, Ikuo
|
|
|
23 |
15 |
p. 5000-5014
|
artikel
|
| 20 |
Design, synthesis and preliminary bioactivity evaluations of substituted quinoline hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors
|
Wang, Lei
|
|
|
23 |
15 |
p. 4364-4374
|
artikel
|
| 21 |
Design, synthesis and preliminary biological evaluation of indoline-2,3-dione derivatives as novel HDAC inhibitors
|
Jin, Kang
|
|
|
23 |
15 |
p. 4728-4736
|
artikel
|
| 22 |
Development of novel DIF-1 derivatives that selectively suppress innate immune responses
|
Nguyen, Van Hai
|
|
|
23 |
15 |
p. 4311-4315
|
artikel
|
| 23 |
Discovery and structural analyses of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogs
|
Nakao, Akira
|
|
|
23 |
15 |
p. 4952-4969
|
artikel
|
| 24 |
Discovery of a 1-isopropyltetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain
|
Ogiyama, Takashi
|
|
|
23 |
15 |
p. 4624-4637
|
artikel
|
| 25 |
Discovery of an 8-methoxytetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain without CYP inhibition liability
|
Ogiyama, Takashi
|
|
|
23 |
15 |
p. 4638-4648
|
artikel
|
| 26 |
Discovery of a novel class anti-proliferative agents and potential inhibitors of EGFR tyrosine kinases based on 4-anilinotetrahydropyrido[4,3-d]pyrimidine scaffold: Design, synthesis and biological evaluations
|
Zhang, Yong
|
|
|
23 |
15 |
p. 4591-4607
|
artikel
|
| 27 |
Discovery of 3,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2(1H)-one derivatives as novel JAK inhibitors
|
Yamagishi, Hiroaki
|
|
|
23 |
15 |
p. 4846-4859
|
artikel
|
| 28 |
Discovery of natural alkaloid bouchardatine as a novel inhibitor of adipogenesis/lipogenesis in 3T3-L1 adipocytes
|
Rao, Yong
|
|
|
23 |
15 |
p. 4719-4727
|
artikel
|
| 29 |
Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol
|
Noha, Stefan M.
|
|
|
23 |
15 |
p. 4839-4845
|
artikel
|
| 30 |
Discovery of novel N-(5-(tert-butyl)isoxazol-3-yl)-N′-phenylurea analogs as potent FLT3 inhibitors and evaluation of their activity against acute myeloid leukemia in vitro and in vivo
|
Xu, Ying
|
|
|
23 |
15 |
p. 4333-4343
|
artikel
|
| 31 |
Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design
|
Du, Yongli
|
|
|
23 |
15 |
p. 4891-4898
|
artikel
|
| 32 |
Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics
|
Nkizinkiko, Yves
|
|
|
23 |
15 |
p. 4139-4149
|
artikel
|
| 33 |
Discovery of small molecules with vasodilating characteristics and adjustable hydrolytic behavior
|
Brunhofer-Bolzer, Gerda
|
|
|
23 |
15 |
p. 4710-4718
|
artikel
|
| 34 |
Discovery of substituted 1,4-dihydroquinolines as novel class of ABCB1 modulators
|
Hemmer, Marc
|
|
|
23 |
15 |
p. 5015-5021
|
artikel
|
| 35 |
Double Sonogashira reactions on dihalogenated aminopyridines for the assembly of an array of 7-azaindoles bearing triazole and quinoxaline substituents at C-5: Inhibitory bioactivity against Giardia duodenalis trophozoites
|
Leboho, Tlabo C.
|
|
|
23 |
15 |
p. 4943-4951
|
artikel
|
| 36 |
Editorial board
|
|
|
|
23 |
15 |
p. IFC
|
artikel
|
| 37 |
Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi
|
García Liñares, Guadalupe
|
|
|
23 |
15 |
p. 4804-4814
|
artikel
|
| 38 |
Graphical contents list
|
|
|
|
23 |
15 |
p. 4093-4118
|
artikel
|
| 39 |
Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens
|
Arai, Midori A.
|
|
|
23 |
15 |
p. 4150-4154
|
artikel
|
| 40 |
How to find the optimal partner—studies of snurportin 1 interactions with U snRNA 5′ TMG-cap analogues containing modified 2-amino group of 7-methylguanosine
|
Piecyk, Karolina
|
|
|
23 |
15 |
p. 4660-4668
|
artikel
|
| 41 |
Hybrid chemistry. Part 4: Discovery of etravirine–VRX-480773 hybrids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
|
Wan, Zheng-Yong
|
|
|
23 |
15 |
p. 4248-4255
|
artikel
|
| 42 |
Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression
|
Duan, Hongliang
|
|
|
23 |
15 |
p. 4514-4521
|
artikel
|
| 43 |
Identification of peptidic substrates for the human kinase Myt1 using peptide microarrays
|
Rohe, Alexander
|
|
|
23 |
15 |
p. 4936-4942
|
artikel
|
| 44 |
Imidazole clubbed 1,3,4-oxadiazole derivatives as potential antifungal agents
|
Wani, Mohmmad Younus
|
|
|
23 |
15 |
p. 4172-4180
|
artikel
|
| 45 |
Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties
|
Ceruso, Mariangela
|
|
|
23 |
15 |
p. 4181-4187
|
artikel
|
| 46 |
In silico investigation of FOXM1 binding and novel inhibitors in epithelial ovarian cancer
|
Chen, Yi
|
|
|
23 |
15 |
p. 4576-4582
|
artikel
|
| 47 |
Instructions to contributors
|
|
|
|
23 |
15 |
p. I
|
artikel
|
| 48 |
Intriguing possibilities and beneficial aspects of transporter-conscious drug design
|
Tashima, Toshihiko
|
|
|
23 |
15 |
p. 4119-4131
|
artikel
|
| 49 |
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine
|
Taleli, Lebusetsa
|
|
|
23 |
15 |
p. 4163-4171
|
artikel
|
| 50 |
In vitro evaluation and in silico screening of synthetic acetylcholinesterase inhibitors bearing functionalized piperidine pharmacophores
|
Brahmachari, Goutam
|
|
|
23 |
15 |
p. 4567-4575
|
artikel
|
| 51 |
Lipocarbazole, an efficient lipid peroxidation inhibitor anchored in the membrane
|
Fabre, Gabin
|
|
|
23 |
15 |
p. 4866-4870
|
artikel
|
| 52 |
Modified quaternary ammonium salts as potential antimalarial agents
|
Basilico, Nicoletta
|
|
|
23 |
15 |
p. 4681-4687
|
artikel
|
| 53 |
Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole
|
Clausen, Dane J.
|
|
|
23 |
15 |
p. 5061-5074
|
artikel
|
| 54 |
N-[(2,6-Dimethylphenoxy)alkyl]aminoalkanols—their physicochemical and anticonvulsant properties
|
Waszkielewicz, Anna M.
|
|
|
23 |
15 |
p. 4197-4217
|
artikel
|
| 55 |
New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds
|
Zhang, Yu
|
|
|
23 |
15 |
p. 4815-4823
|
artikel
|
| 56 |
N-mustard analogs of S-adenosyl-l-methionine as biochemical probes of protein arginine methylation
|
Hymbaugh Bergman, Sarah J.
|
|
|
23 |
15 |
p. 5050-5055
|
artikel
|
| 57 |
NO-donor thiacarbocyanines as multifunctional agents for Alzheimer’s disease
|
Chegaev, Konstantin
|
|
|
23 |
15 |
p. 4688-4698
|
artikel
|
| 58 |
Novel inhibitors of RANKL-induced osteoclastogenesis: Design, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones
|
Lee, Chia-Chung
|
|
|
23 |
15 |
p. 4522-4532
|
artikel
|
| 59 |
4-(N-Phenyl-N′-substituted benzenesulfonyl)-6-(4-hydroxyphenyl)quinolines as inhibitors of mammalian target of rapamycin
|
Venkateswarlu, Vunnam
|
|
|
23 |
15 |
p. 4237-4247
|
artikel
|
| 60 |
One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases
|
Kiebist, Jan
|
|
|
23 |
15 |
p. 4324-4332
|
artikel
|
| 61 |
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities
|
Sato, Kenjiro
|
|
|
23 |
15 |
p. 4544-4560
|
artikel
|
| 62 |
Optimization of histone deacetylase inhibitor activity in non-secosteroidal vitamin D-receptor agonist hybrids
|
Kaldre, Dainis
|
|
|
23 |
15 |
p. 5035-5049
|
artikel
|
| 63 |
Orally active ghrelin receptor inverse agonists and their actions on a rat obesity model
|
Takahashi, Bitoku
|
|
|
23 |
15 |
p. 4792-4803
|
artikel
|
| 64 |
PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells
|
Kim, Youseung
|
|
|
23 |
15 |
p. 4980-4988
|
artikel
|
| 65 |
Pentamidine analogs as inhibitors of [3H]MK-801 and [3H]ifenprodil binding to rat brain NMDA receptors
|
Berger, Michael L.
|
|
|
23 |
15 |
p. 4489-4500
|
artikel
|
| 66 |
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE)
|
Choi, Kwanghyun
|
|
|
23 |
15 |
p. 4919-4935
|
artikel
|
| 67 |
Plasmid DNA delivery using fluorescein-labeled arginine-rich peptides
|
Oba, Makoto
|
|
|
23 |
15 |
p. 4911-4918
|
artikel
|
| 68 |
Potential antibacterial activity of triazine dendrimer: Synthesis and controllable drug release properties
|
Vembu, Sandhirakasu
|
|
|
23 |
15 |
p. 4561-4566
|
artikel
|
| 69 |
Pyrrolo[2,3-b]pyridine derivatives as potent Bruton’s tyrosine kinase inhibitors
|
Zhao, Xinge
|
|
|
23 |
15 |
p. 4344-4353
|
artikel
|
| 70 |
Retraction notice to ‘Design and synthesis of CHAP31, trapoxin B and HC-toxin based bicyclic tetrapeptides disulfide as potent histone deacetylase inhibitors’ [Bioorg Med Chem 22 (2014) 3850–3855]
|
Hoque, Md. Ashraful
|
|
|
23 |
15 |
p. 5078
|
artikel
|
| 71 |
Ring-substituted 8-hydroxyquinoline-2-carboxanilides as potential antimycobacterial agents
|
Kos, Jiri
|
|
|
23 |
15 |
p. 4188-4196
|
artikel
|
| 72 |
Selenorhodamine photosensitizers with the Texas-red core for photodynamic therapy of cancer cells
|
Kryman, Mark W.
|
|
|
23 |
15 |
p. 4501-4507
|
artikel
|
| 73 |
Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium
|
Karmakar, Utpal K.
|
|
|
23 |
15 |
p. 4746-4754
|
artikel
|
| 74 |
Stereoselective synthesis and pharmacological evaluation of [4.3.3]propellan-8-amines as analogs of adamantanamines
|
Torres-Gómez, Héctor
|
|
|
23 |
15 |
p. 4277-4285
|
artikel
|
| 75 |
Strong positive cooperativity in binding to the A3T3 repeat by Hoechst 33258 derivatives attaching the quinoline units at the end of a branched linker
|
Koda, Hironori
|
|
|
23 |
15 |
p. 4583-4590
|
artikel
|
| 76 |
Structural development of stabilized helical peptides as inhibitors of estrogen receptor (ER)-mediated transcription
|
Demizu, Yosuke
|
|
|
23 |
15 |
p. 4132-4138
|
artikel
|
| 77 |
Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa
|
Pinard, Melissa A.
|
|
|
23 |
15 |
p. 4831-4838
|
artikel
|
| 78 |
Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents
|
Knez, Damijan
|
|
|
23 |
15 |
p. 4442-4452
|
artikel
|
| 79 |
Structure Based Library Design (SBLD) for new 1,4-dihydropyrimidine scaffold as simultaneous COX-1/COX-2 and 5-LOX inhibitors
|
Lokwani, Deepak
|
|
|
23 |
15 |
p. 4533-4543
|
artikel
|
| 80 |
Studies on the preferred uracil–adenine base pair at the cleavage site of 10–23 DNAzyme by functional group modifications on adenine
|
Zhu, Junfei
|
|
|
23 |
15 |
p. 4256-4263
|
artikel
|
| 81 |
4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site
|
Pogorelčnik, Barbara
|
|
|
23 |
15 |
p. 4218-4229
|
artikel
|
| 82 |
Synthesis and antileukemic activities of C1–C10-modified parthenolide analogues
|
Kempema, Aaron M.
|
|
|
23 |
15 |
p. 4737-4745
|
artikel
|
| 83 |
Synthesis and anti-Trypanosoma cruzi activity of new 3‐phenylthio-nor-β-lapachone derivatives
|
Cardoso, Mariana F. do Carmo
|
|
|
23 |
15 |
p. 4763-4768
|
artikel
|
| 84 |
Synthesis and bioactivity of a Goralatide analog with antileukemic activity
|
Li, Zhiliang
|
|
|
23 |
15 |
p. 5056-5060
|
artikel
|
| 85 |
Synthesis and bioevaluation of heterocyclic derivatives of Cleistanthin-A
|
Zhao, Yu
|
|
|
23 |
15 |
p. 4884-4890
|
artikel
|
| 86 |
Synthesis and biological activity of novel deoxycholic acid derivatives
|
Popadyuk, Irina I.
|
|
|
23 |
15 |
p. 5022-5034
|
artikel
|
| 87 |
Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter
|
Tu, Zhude
|
|
|
23 |
15 |
p. 4699-4709
|
artikel
|
| 88 |
Synthesis and biological evaluation of isoflavone amide derivatives with antihyperlipidemic and preadipocyte antiproliferative activities
|
Wang, Wenbin
|
|
|
23 |
15 |
p. 4428-4433
|
artikel
|
| 89 |
Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity
|
Duan, Wenwen
|
|
|
23 |
15 |
p. 4481-4488
|
artikel
|
| 90 |
Synthesis and evaluation of hedgehog signaling inhibitor with novel core system
|
Ohashi, Tomohiro
|
|
|
23 |
15 |
p. 4777-4791
|
artikel
|
| 91 |
Synthesis and evaluation of N-analogs of 1,2-diarylethane as Helicobacter pylori urease inhibitors
|
Xiao, Zhu-Ping
|
|
|
23 |
15 |
p. 4508-4513
|
artikel
|
| 92 |
Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3
|
Nakajima, Yutaka
|
|
|
23 |
15 |
p. 4871-4883
|
artikel
|
| 93 |
Synthesis and evaluation of the anti-nociceptive and anti-inflammatory activity of 4-aminoquinoline derivatives
|
de Meneses Santos, Raquel
|
|
|
23 |
15 |
p. 4390-4396
|
artikel
|
| 94 |
Synthesis and in vitro kinetic evaluation of N-thiazolylacetamido monoquaternary pyridinium oximes as reactivators of sarin, O-ethylsarin and VX inhibited human acetylcholinesterase (hAChE)
|
Valiveti, Aditya Kapil
|
|
|
23 |
15 |
p. 4899-4910
|
artikel
|
| 95 |
Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor
|
Stehouwer, Jeffrey S.
|
|
|
23 |
15 |
p. 4286-4302
|
artikel
|
| 96 |
Synthesis, β-hematin inhibition studies and antimalarial evaluation of dehydroxy isotebuquine derivatives against Plasmodium berghei
|
Romero, Angel H.
|
|
|
23 |
15 |
p. 4755-4762
|
artikel
|
| 97 |
Synthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent
|
Wang, Xu-Dong
|
|
|
23 |
15 |
p. 4860-4865
|
artikel
|
| 98 |
Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects
|
Lee, Young Hun
|
|
|
23 |
15 |
p. 4970-4979
|
artikel
|
| 99 |
Synthesis of 2-aryl-1,2,4-oxadiazolo-benzimidazoles: Tubulin polymerization inhibitors and apoptosis inducing agents
|
Kamal, Ahmed
|
|
|
23 |
15 |
p. 4608-4623
|
artikel
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| 100 |
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