| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Acylated glucosylflavones as α-glucosidase inhibitors from Tinospora crispa leaf
|
Chang, Chi-Chih
|
|
2015
|
23 |
13 |
p. 3388-3396
9 p.
|
artikel
|
| 2 |
Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436
|
Hamaguchi, Wataru
|
|
2015
|
23 |
13 |
p. 3351-3367
17 p.
|
artikel
|
| 3 |
Anti-arthritic agents: Progress and potential
|
Laev, Sergey S.
|
|
2015
|
23 |
13 |
p. 3059-3080
22 p.
|
artikel
|
| 4 |
Anticancer activity of koningic acid and semisynthetic derivatives
|
Rahier, Nicolas J.
|
|
2015
|
23 |
13 |
p. 3712-3721
10 p.
|
artikel
|
| 5 |
Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp.
|
Arai, Masayoshi
|
|
2015
|
23 |
13 |
p. 3534-3541
8 p.
|
artikel
|
| 6 |
Anti-HIV diarylpyrimidine–quinolone hybrids and their mode of action
|
Mao, Tian-Qi
|
|
2015
|
23 |
13 |
p. 3860-3868
9 p.
|
artikel
|
| 7 |
Anti-MRSA activity of isoplagiochin-type macrocyclic bis(bibenzyl)s is mediated through cell membrane damage
|
Onoda, Kenji
|
|
2015
|
23 |
13 |
p. 3309-3316
8 p.
|
artikel
|
| 8 |
1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose
|
Xu, Shilin
|
|
2015
|
23 |
13 |
p. 3751-3760
10 p.
|
artikel
|
| 9 |
Chimeric derivatives of functionalized amino acids and α-aminoamides: Compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels
|
Torregrosa, Robert
|
|
2015
|
23 |
13 |
p. 3655-3666
12 p.
|
artikel
|
| 10 |
Cloning, characterization and anion inhibition study of a β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans
|
Dedeoglu, Nurcan
|
|
2015
|
23 |
13 |
p. 2995-3001
7 p.
|
artikel
|
| 11 |
Colloidal and antibacterial properties of novel triple-headed, double-tailed amphiphiles: Exploring structure–activity relationships and synergistic mixtures
|
Marafino, John N.
|
|
2015
|
23 |
13 |
p. 3566-3573
8 p.
|
artikel
|
| 12 |
Combination of 4-anilinoquinazoline and rhodanine as novel epidermal growth factor receptor tyrosine kinase inhibitors
|
Li, Si-Ning
|
|
2015
|
23 |
13 |
p. 3221-3227
7 p.
|
artikel
|
| 13 |
Corrigendum to “Design, synthesis, and structure–activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists” [Bioorg. Med. Chem. 22 (2014) 6071–6088]
|
Yoshida, Yu
|
|
2015
|
23 |
13 |
p. 3870-
1 p.
|
artikel
|
| 14 |
Corrigendum to “Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis” [Bioorg. Med. Chem. 23 (2015) 742–752]
|
Singh, Supriya
|
|
2015
|
23 |
13 |
p. 3871-
1 p.
|
artikel
|
| 15 |
Corrigendum to “The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments” [Bioorg. Med. Chem. 22 (2014) 4462–4473]
|
Tony Liu, C.
|
|
2015
|
23 |
13 |
p. 3869-
1 p.
|
artikel
|
| 16 |
Design and synthesis of a crosslinker for studying intracellular steroid trafficking pathways
|
Byrd, Katherine M.
|
|
2015
|
23 |
13 |
p. 3843-3851
9 p.
|
artikel
|
| 17 |
Design and synthesis of novel ROR inverse agonists with a dibenzosilole scaffold as a hydrophobic core structure
|
Toyama, Hirozumi
|
|
2015
|
23 |
13 |
p. 2982-2988
7 p.
|
artikel
|
| 18 |
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues
|
Kokosza, Kamil
|
|
2015
|
23 |
13 |
p. 3135-3146
12 p.
|
artikel
|
| 19 |
Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides
|
Mokrov, G.V.
|
|
2015
|
23 |
13 |
p. 3368-3378
11 p.
|
artikel
|
| 20 |
Design, synthesis, and biological activity of phenyl-pyrazole derivatives as BCR–ABL kinase inhibitors
|
Hu, Liming
|
|
2015
|
23 |
13 |
p. 3147-3152
6 p.
|
artikel
|
| 21 |
Design, synthesis, and biological evaluation of a series of alkoxy-3-indolylacetic acids as peroxisome proliferator-activated receptor γ/δ agonists
|
Gim, Hyo Jin
|
|
2015
|
23 |
13 |
p. 3322-3336
15 p.
|
artikel
|
| 22 |
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents
|
Abdelazeem, Ahmed H.
|
|
2015
|
23 |
13 |
p. 3248-3259
12 p.
|
artikel
|
| 23 |
Design, synthesis and evaluation of novel 2-butyl-4-chloroimidazole derived peptidomimetics as Angiotensin Converting Enzyme (ACE) inhibitors
|
Jallapally, Anvesh
|
|
2015
|
23 |
13 |
p. 3526-3533
8 p.
|
artikel
|
| 24 |
Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1
|
Penthala, Narsimha R.
|
|
2015
|
23 |
13 |
p. 3681-3686
6 p.
|
artikel
|
| 25 |
Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B
|
Vezenkov, Lubomir
|
|
2015
|
23 |
13 |
p. 3237-3247
11 p.
|
artikel
|
| 26 |
Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents
|
Cai, Jin
|
|
2015
|
23 |
13 |
p. 3457-3471
15 p.
|
artikel
|
| 27 |
Discovery of biphenyl-aryl ureas as novel VEGFR-2 inhibitors. Part 4: Exploration of diverse hinge-binding fragments
|
Su, Ping
|
|
2015
|
23 |
13 |
p. 3228-3236
9 p.
|
artikel
|
| 28 |
Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators
|
Chang, Ken-Ming
|
|
2015
|
23 |
13 |
p. 3852-3859
8 p.
|
artikel
|
| 29 |
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones
|
Akıncıoğlu, Akın
|
|
2015
|
23 |
13 |
p. 3592-3602
11 p.
|
artikel
|
| 30 |
Editorial board
|
|
|
2015
|
23 |
13 |
p. IFC-
1 p.
|
artikel
|
| 31 |
Effect of chirality on cellular uptake, imaging and photodynamic therapy of photosensitizers derived from chlorophyll-a
|
Srivatsan, Avinash
|
|
2015
|
23 |
13 |
p. 3603-3617
15 p.
|
artikel
|
| 32 |
Effect of deuteration on metabolism and clearance of Nerispirdine (HP184) and AVE5638
|
Schofield, Joseph
|
|
2015
|
23 |
13 |
p. 3831-3842
12 p.
|
artikel
|
| 33 |
Effect of intercalator substituent and nucleotide sequence on the stability of DNA- and RNA-naphthalimide complexes
|
Johnson, Charles A.
|
|
2015
|
23 |
13 |
p. 3586-3591
6 p.
|
artikel
|
| 34 |
Effect of water solvation on the lipophilicity of isomeric pyrimidine-carboxamides
|
Linton, Maria Angelica
|
|
2015
|
23 |
13 |
p. 3408-3413
6 p.
|
artikel
|
| 35 |
Efficient method for iodine radioisotope labeling of cyclooctyne-containing molecules using strain-promoted copper-free click reaction
|
Jeon, Jongho
|
|
2015
|
23 |
13 |
p. 3303-3308
6 p.
|
artikel
|
| 36 |
Enhanced detection of type C botulinum neurotoxin by the Endopep-MS assay through optimization of peptide substrates
|
Wang, Dongxia
|
|
2015
|
23 |
13 |
p. 3667-3673
7 p.
|
artikel
|
| 37 |
Exploring S1 plasticity and probing S1′ subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors
|
Revelant, Germain
|
|
2015
|
23 |
13 |
p. 3192-3207
16 p.
|
artikel
|
| 38 |
Exploring the isoform selectivity of TGX-221 related pyrido[1,2-a]pyrimidinone-based Class IA PI 3-kinase inhibitors: Synthesis, biological evaluation and molecular modelling
|
Marshall, Andrew J.
|
|
2015
|
23 |
13 |
p. 3796-3808
13 p.
|
artikel
|
| 39 |
Exploring the structure–activity relationships of ABCC2 modulators using a screening approach
|
Wissel, Gloria
|
|
2015
|
23 |
13 |
p. 3513-3525
13 p.
|
artikel
|
| 40 |
Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties
|
Flesch, Daniel
|
|
2015
|
23 |
13 |
p. 3490-3498
9 p.
|
artikel
|
| 41 |
Glycosyl hydroperoxides: A new class of potential antimalarial agents
|
Szechner, Barbara
|
|
2015
|
23 |
13 |
p. 3033-3039
7 p.
|
artikel
|
| 42 |
Graphical contents list
|
|
|
2015
|
23 |
13 |
p. 2929-2952
24 p.
|
artikel
|
| 43 |
Higenamine 4′-O-β-d-glucoside in the lotus plumule induces glucose uptake of L6 cells through β2-adrenergic receptor
|
Kato, Eisuke
|
|
2015
|
23 |
13 |
p. 3317-3321
5 p.
|
artikel
|
| 44 |
Identification of p-hydroxybenzyl alcohol, tyrosol, phloretin and its derivate phloridzin as tyrosinase substrates
|
Ortiz-Ruiz, Carmen Vanessa
|
|
2015
|
23 |
13 |
p. 3738-3746
9 p.
|
artikel
|
| 45 |
Influence of linker length in shape recognition of B∗ DNA by dimeric aminoglycosides
|
Kumar, Sunil
|
|
2015
|
23 |
13 |
p. 3105-3109
5 p.
|
artikel
|
| 46 |
Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation
|
Imai, Masahiko
|
|
2015
|
23 |
13 |
p. 3788-3795
8 p.
|
artikel
|
| 47 |
Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems
|
Twum, Elvis A.
|
|
2015
|
23 |
13 |
p. 3481-3489
9 p.
|
artikel
|
| 48 |
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity
|
Anighoro, Andrew
|
|
2015
|
23 |
13 |
p. 3040-3058
19 p.
|
artikel
|
| 49 |
In silico evaluation of human small heat shock protein HSP27: Homology modeling, mutation analyses and docking studies
|
Fossa, Paola
|
|
2015
|
23 |
13 |
p. 3215-3220
6 p.
|
artikel
|
| 50 |
Isolation of cholinesterase and β-secretase 1 inhibiting compounds from Lycopodiella cernua
|
Nguyen, Van Thu
|
|
2015
|
23 |
13 |
p. 3126-3134
9 p.
|
artikel
|
| 51 |
Macrocyclic analogues of the diuretic insect neuropeptide helicokinin I show strong receptor-binding
|
Tran Van, Chien
|
|
2015
|
23 |
13 |
p. 3278-3286
9 p.
|
artikel
|
| 52 |
Macrocyclic naphthalene diimides as G-quadruplex binders
|
Marchetti, Chiara
|
|
2015
|
23 |
13 |
p. 3819-3830
12 p.
|
artikel
|
| 53 |
(−)-Meptazinol–melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-β aggregation with high antioxidant potency for Alzheimer’s therapy
|
Cheng, Shaobing
|
|
2015
|
23 |
13 |
p. 3110-3118
9 p.
|
artikel
|
| 54 |
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: Biological evaluation and molecular modelling studies
|
Carradori, Simone
|
|
2015
|
23 |
13 |
p. 2975-2981
7 p.
|
artikel
|
| 55 |
New matrix metalloproteinase inhibitors based on γ-fluorinated α-aminocarboxylic and α-aminohydroxamic acids
|
Behrends, Malte
|
|
2015
|
23 |
13 |
p. 3809-3818
10 p.
|
artikel
|
| 56 |
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors
|
Mojzych, Mariusz
|
|
2015
|
23 |
13 |
p. 3674-3680
7 p.
|
artikel
|
| 57 |
nor-Mevaldic acid surrogates as selective antifungal agent leads against Botrytis cinerea. Enantioselective preparation of 4-hydroxy-6-(1-phenylethoxy)tetrahydro-2H-pyran-2-one
|
Botubol-Ares, José Manuel
|
|
2015
|
23 |
13 |
p. 3379-3387
9 p.
|
artikel
|
| 58 |
Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: A new class of β-glucuronidase inhibitors and in silico studies
|
Zawawi, Nik Khairunissa Nik Abdullah
|
|
2015
|
23 |
13 |
p. 3119-3125
7 p.
|
artikel
|
| 59 |
Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior
|
Cui, Jin
|
|
2015
|
23 |
13 |
p. 2989-2994
6 p.
|
artikel
|
| 60 |
Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent
|
Czopek, Anna
|
|
2015
|
23 |
13 |
p. 3436-3447
12 p.
|
artikel
|
| 61 |
Novel type of plasmin inhibitors: Providing insight into P4 moiety and alternative scaffold to pyrrolopyrimidine
|
Teno, Naoki
|
|
2015
|
23 |
13 |
p. 3696-3704
9 p.
|
artikel
|
| 62 |
Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug–drug interactions and P-gp liability
|
Kunikawa, Shigeki
|
|
2015
|
23 |
13 |
p. 3269-3277
9 p.
|
artikel
|
| 63 |
Optimization of rhodanine scaffold for the development of protein–protein interaction inhibitors
|
Ferro, Stefania
|
|
2015
|
23 |
13 |
p. 3208-3214
7 p.
|
artikel
|
| 64 |
Phospholipid derivatives of cladribine and fludarabine: Synthesis and biological properties
|
Tsybulskaya, Ilona
|
|
2015
|
23 |
13 |
p. 3287-3296
10 p.
|
artikel
|
| 65 |
Potent antimicrobial agents against azole-resistant fungi based on pyridinohydrazide and hydrazomethylpyridine structural motifs
|
Backes, Gregory L.
|
|
2015
|
23 |
13 |
p. 3397-3407
11 p.
|
artikel
|
| 66 |
Preparation and biological evaluation of conformationally constrained BACE1 inhibitors
|
Winneroski, Leonard L.
|
|
2015
|
23 |
13 |
p. 3260-3268
9 p.
|
artikel
|
| 67 |
Protonography, a powerful tool for analyzing the activity and the oligomeric state of the γ-carbonic anhydrase identified in the genome of Porphyromonas gingivalis
|
Del Prete, Sonia
|
|
2015
|
23 |
13 |
p. 3747-3750
4 p.
|
artikel
|
| 68 |
Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects
|
Nguyen, Phi-Hung
|
|
2015
|
23 |
13 |
p. 3730-3737
8 p.
|
artikel
|
| 69 |
Selective induction of oxidative stress in cancer cells via synergistic combinations of agents targeting redox homeostasis
|
Akladios, Fady N.
|
|
2015
|
23 |
13 |
p. 3097-3104
8 p.
|
artikel
|
| 70 |
Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates
|
Vasta, James D.
|
|
2015
|
23 |
13 |
p. 3081-3090
10 p.
|
artikel
|
| 71 |
Simple structural modifications confer cytotoxicity to allobetulin
|
Heller, Lucie
|
|
2015
|
23 |
13 |
p. 3002-3012
11 p.
|
artikel
|
| 72 |
Structure–activity relationship studies on acremomannolipin A, the potent calcium signal modulator with a novel glycolipid structure 3: Role of the length of alditol side chain
|
Tsutsui, Nozomi
|
|
2015
|
23 |
13 |
p. 3761-3773
13 p.
|
artikel
|
| 73 |
Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogs
|
Yadav, Arun A.
|
|
2015
|
23 |
13 |
p. 3542-3551
10 p.
|
artikel
|
| 74 |
Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases
|
Kumpan, Katerina
|
|
2015
|
23 |
13 |
p. 3013-3032
20 p.
|
artikel
|
| 75 |
Studies of binding interactions between Dufulin and southern rice black-streaked dwarf virus P9-1
|
Li, Xiangyang
|
|
2015
|
23 |
13 |
p. 3629-3637
9 p.
|
artikel
|
| 76 |
Synthesis and antibacterial activities of cadiolides A, B and C and analogues
|
Boulangé, Agathe
|
|
2015
|
23 |
13 |
p. 3618-3628
11 p.
|
artikel
|
| 77 |
Synthesis and antimicrobial activity of chloramphenicol–polyamine conjugates
|
Magoulas, George E.
|
|
2015
|
23 |
13 |
p. 3163-3174
12 p.
|
artikel
|
| 78 |
Synthesis and biological evaluation of caracasine acid derivatives
|
Chávez, Katiuska
|
|
2015
|
23 |
13 |
p. 3687-3695
9 p.
|
artikel
|
| 79 |
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity
|
Wang, Fang
|
|
2015
|
23 |
13 |
p. 3337-3350
14 p.
|
artikel
|
| 80 |
Synthesis and biological evaluation of thiabendazole derivatives as anti-angiogenesis and vascular disrupting agents
|
Zhang, Chao
|
|
2015
|
23 |
13 |
p. 3774-3780
7 p.
|
artikel
|
| 81 |
Synthesis and discovery of (I-3,II-3)-biacacetin as a novel non-zinc binding inhibitor of MMP-2 and MMP-9
|
Nanjan, Pandurangan
|
|
2015
|
23 |
13 |
p. 3781-3787
7 p.
|
artikel
|
| 82 |
Synthesis and evaluation of quinazoline amino acid derivatives as mono amine oxidase (MAO) inhibitors
|
Khattab, Sherine Nabil
|
|
2015
|
23 |
13 |
p. 3574-3585
12 p.
|
artikel
|
| 83 |
Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer’s disease
|
Xie, Shishun
|
|
2015
|
23 |
13 |
p. 3722-3729
8 p.
|
artikel
|
| 84 |
Synthesis and evaluation of tamoxifen derivatives with a long alkyl side chain as selective estrogen receptor down-regulators
|
Shoda, Takuji
|
|
2015
|
23 |
13 |
p. 3091-3096
6 p.
|
artikel
|
| 85 |
Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors
|
Pingaew, Ratchanok
|
|
2015
|
23 |
13 |
p. 3472-3480
9 p.
|
artikel
|
| 86 |
Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides
|
Brucoli, Federico
|
|
2015
|
23 |
13 |
p. 3705-3711
7 p.
|
artikel
|
| 87 |
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors
|
Brullo, Chiara
|
|
2015
|
23 |
13 |
p. 3426-3435
10 p.
|
artikel
|
| 88 |
Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists
|
Guillaume, Joren
|
|
2015
|
23 |
13 |
p. 3175-3182
8 p.
|
artikel
|
| 89 |
Synthesis, structure elucidation and identification of antiproliferative activities of a novel class of thiophene bioisosteres bearing the privileged 7,8-dihydroimidazo[2,1-c][1,2,4]triazin-4(6H)-one scaffold
|
Sztanke, Małgorzata
|
|
2015
|
23 |
13 |
p. 3448-3456
9 p.
|
artikel
|
| 90 |
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines
|
Kadayat, Tara Man
|
|
2015
|
23 |
13 |
p. 3499-3512
14 p.
|
artikel
|
| 91 |
Synthetic 1,2,3-triazole-linked glycoconjugates bind with high affinity to human galectin-3
|
Marchiori, Marcelo Fiori
|
|
2015
|
23 |
13 |
p. 3414-3425
12 p.
|
artikel
|
| 92 |
Systematic assessment of scaffold hopping versus activity cliff formation across bioactive compound classes following a molecular hierarchy
|
Stumpfe, Dagmar
|
|
2015
|
23 |
13 |
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