| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: Synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis
|
Khan, Imtiaz
|
|
2014
|
22 |
21 |
p. 6163-6173
11 p.
|
artikel
|
| 2 |
AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: Identification, SAR and pharmacological characterization
|
Vranesic, Ivo
|
|
2014
|
22 |
21 |
p. 5790-5803
14 p.
|
artikel
|
| 3 |
Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi
|
Bashyal, Bharat P.
|
|
2014
|
22 |
21 |
p. 6112-6116
5 p.
|
artikel
|
| 4 |
Betulin derivatives impair Leishmania braziliensis viability and host–parasite interaction
|
Alcazar, Wilmer
|
|
2014
|
22 |
21 |
p. 6220-6226
7 p.
|
artikel
|
| 5 |
2-(2-Bromophenyl)-formononetin and 2-heptyl-formononetin are PPARγ partial agonists and reduce lipid accumulation in 3T3-L1 adipocytes
|
Andersen, Charlotte
|
|
2014
|
22 |
21 |
p. 6105-6111
7 p.
|
artikel
|
| 6 |
Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase
|
Tallorin, Lorillee
|
|
2014
|
22 |
21 |
p. 6053-6061
9 p.
|
artikel
|
| 7 |
Chemical synthesis, cytotoxicity, selectivity and bioavailability of 5α-androstane-3α,17β-diol derivatives
|
Ayan, Diana
|
|
2014
|
22 |
21 |
p. 5847-5859
13 p.
|
artikel
|
| 8 |
Design, synthesis and biological activity of flavonoid derivatives as selective agonists for neuromedin U 2 receptor
|
Ma, Ming-Liang
|
|
2014
|
22 |
21 |
p. 6117-6123
7 p.
|
artikel
|
| 9 |
Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors
|
Yang, Wei
|
|
2014
|
22 |
21 |
p. 6146-6155
10 p.
|
artikel
|
| 10 |
Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAFV600E inhibitors
|
Wang, Shu-Fu
|
|
2014
|
22 |
21 |
p. 6201-6208
8 p.
|
artikel
|
| 11 |
Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles
|
Li , Zeng
|
|
2014
|
22 |
21 |
p. 5838-5846
9 p.
|
artikel
|
| 12 |
Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer’s disease
|
Lan, Jin-Shuai
|
|
2014
|
22 |
21 |
p. 6089-6104
16 p.
|
artikel
|
| 13 |
Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol
|
Fernández-Tejada, Alberto
|
|
2014
|
22 |
21 |
p. 5917-5923
7 p.
|
artikel
|
| 14 |
Design, synthesis and pharmacological evaluation of chalcone derivatives as acetylcholinesterase inhibitors
|
Liu, Hao-ran
|
|
2014
|
22 |
21 |
p. 6124-6133
10 p.
|
artikel
|
| 15 |
Design, synthesis, and structure–activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists
|
Yoshida, Yu
|
|
2014
|
22 |
21 |
p. 6071-6088
18 p.
|
artikel
|
| 16 |
Design, synthesis and structure–activity relationship studies of morpholino-1H-phenalene derivatives that antagonize Mcl-1/Bcl-2
|
Li, Xiangqian
|
|
2014
|
22 |
21 |
p. 5738-5746
9 p.
|
artikel
|
| 17 |
Development of benzo[d]oxazol-2(3H)-ones derivatives as novel inhibitors of Mycobacterium tuberculosis InhA
|
Pedgaonkar, Ganesh S.
|
|
2014
|
22 |
21 |
p. 6134-6145
12 p.
|
artikel
|
| 18 |
Direct evidence for the function of crustacean insulin-like androgenic gland factor (IAG): Total chemical synthesis of IAG
|
Katayama, Hidekazu
|
|
2014
|
22 |
21 |
p. 5783-5789
7 p.
|
artikel
|
| 19 |
Discovery and structure–activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase
|
Zhulenkovs, Dmitrijs
|
|
2014
|
22 |
21 |
p. 5988-6003
16 p.
|
artikel
|
| 20 |
Discovery of 4-aminoquinazoline—urea derivatives as Aurora kinase inhibitors with antiproliferative activity
|
Cai, Jin
|
|
2014
|
22 |
21 |
p. 5813-5823
11 p.
|
artikel
|
| 21 |
Editorial board
|
|
|
2014
|
22 |
21 |
p. IFC-
1 p.
|
artikel
|
| 22 |
Effect of dehydroepiandrosterone derivatives on the activity of 5α-reductase isoenzymes and on cancer cell line PC-3
|
Bratoeff, Eugene
|
|
2014
|
22 |
21 |
p. 6233-6241
9 p.
|
artikel
|
| 23 |
Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism
|
Meneely, Kathleen M.
|
|
2014
|
22 |
21 |
p. 5961-5969
9 p.
|
artikel
|
| 24 |
Graphical contents list
|
|
|
2014
|
22 |
21 |
p. 5705-5720
16 p.
|
artikel
|
| 25 |
hERG blocking potential of acids and zwitterions characterized by three thresholds for acidity, size and reactivity
|
Nikolov, Nikolai G.
|
|
2014
|
22 |
21 |
p. 6004-6013
10 p.
|
artikel
|
| 26 |
Human α1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines
|
Chen, Junli
|
|
2014
|
22 |
21 |
p. 5910-5916
7 p.
|
artikel
|
| 27 |
γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: A study of their activity as glycosidase inhibitors and as immunosuppressive agents
|
Markad, Pramod R.
|
|
2014
|
22 |
21 |
p. 5776-5782
7 p.
|
artikel
|
| 28 |
Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif
|
Guan, Peng
|
|
2014
|
22 |
21 |
p. 5766-5775
10 p.
|
artikel
|
| 29 |
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: Identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones
|
Sarikaya, Busra
|
|
2014
|
22 |
21 |
p. 5883-5890
8 p.
|
artikel
|
| 30 |
Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome
|
Kim, Jang Hoon
|
|
2014
|
22 |
21 |
p. 6047-6052
6 p.
|
artikel
|
| 31 |
New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death
|
Serafim, Teresa L.
|
|
2014
|
22 |
21 |
p. 6270-6287
18 p.
|
artikel
|
| 32 |
N-methylthioacetylation of RYYRIK-NH2 with enhanced specific binding affinity and high antagonist activity for nociceptin ORL1 receptor
|
Li, Jinglan
|
|
2014
|
22 |
21 |
p. 5721-5726
6 p.
|
artikel
|
| 33 |
Organochalcogen compounds from glycerol: Synthesis of new antioxidants
|
Nobre, Patrick C.
|
|
2014
|
22 |
21 |
p. 6242-6249
8 p.
|
artikel
|
| 34 |
Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors
|
Hin, Niyada
|
|
2014
|
22 |
21 |
p. 5831-5837
7 p.
|
artikel
|
| 35 |
Pyrazole derivatives as potent inhibitors of c-Jun N-terminal kinase: Synthesis and SAR studies
|
Doma, Anuradha
|
|
2014
|
22 |
21 |
p. 6209-6219
11 p.
|
artikel
|
| 36 |
Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping
|
Doig, Peter
|
|
2014
|
22 |
21 |
p. 6256-6269
14 p.
|
artikel
|
| 37 |
SAR analysis and biological studies of synthesized podophyllum derivates obtained by N linkage modification at C-4 position
|
Wang, Huai
|
|
2014
|
22 |
21 |
p. 6183-6192
10 p.
|
artikel
|
| 38 |
Sequential and parallel dual labeling of nanoparticles using click chemistry
|
Zong, Hong
|
|
2014
|
22 |
21 |
p. 6288-6296
9 p.
|
artikel
|
| 39 |
Simple molecular engineering of glycol nucleic acid: Progression from self-pairing to cross-pairing with cDNA and RNA
|
Bose, Tanaya
|
|
2014
|
22 |
21 |
p. 6227-6232
6 p.
|
artikel
|
| 40 |
Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs
|
Fujii, Shinya
|
|
2014
|
22 |
21 |
p. 5891-5901
11 p.
|
artikel
|
| 41 |
Structure–activity relationships of the thujaplicins for inhibition of human tyrosinase
|
Yoshimori, Atsushi
|
|
2014
|
22 |
21 |
p. 6193-6200
8 p.
|
artikel
|
| 42 |
Structure–activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication
|
Di Mola, Antonia
|
|
2014
|
22 |
21 |
p. 6014-6025
12 p.
|
artikel
|
| 43 |
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin–N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA
|
Yadav, Arun A.
|
|
2014
|
22 |
21 |
p. 5935-5949
15 p.
|
artikel
|
| 44 |
Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus
|
Janupally, Renuka
|
|
2014
|
22 |
21 |
p. 5970-5987
18 p.
|
artikel
|
| 45 |
Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo
|
Spivak, Anna Yu.
|
|
2014
|
22 |
21 |
p. 6297-6304
8 p.
|
artikel
|
| 46 |
Synthesis and evaluation of novel triazoles and mannich bases functionalized 1,4-dihydropyridine as angiotensin converting enzyme (ACE) inhibitors
|
Kumbhare, Ravindra M.
|
|
2014
|
22 |
21 |
p. 5824-5830
7 p.
|
artikel
|
| 47 |
Synthesis and evaluation of pyrazolines bearing benzothiazole as anti-inflammatory agents
|
Kharbanda, Chetna
|
|
2014
|
22 |
21 |
p. 5804-5812
9 p.
|
artikel
|
| 48 |
Synthesis and evaluation of sulfonylethyl-containing phosphotriesters of 3′-azido-3′-deoxythymidine as anticancer prodrugs
|
Wang, Jiang
|
|
2014
|
22 |
21 |
p. 5747-5756
10 p.
|
artikel
|
| 49 |
Synthesis and evaluation of the antiplasmodial activity of novel indeno[2,1-c]quinoline derivatives
|
Barteselli, Anna
|
|
2014
|
22 |
21 |
p. 5757-5765
9 p.
|
artikel
|
| 50 |
Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors
|
Mendieta, Aarón
|
|
2014
|
22 |
21 |
p. 5871-5882
12 p.
|
artikel
|
| 51 |
Synthesis and in vitro evaluation of radioiodinated indolequinones targeting NAD(P)H: Quinone oxidoreductase 1 for internal radiation therapy
|
Sasaki, Junichi
|
|
2014
|
22 |
21 |
p. 6039-6046
8 p.
|
artikel
|
| 52 |
Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists
|
Moritomo, Ayako
|
|
2014
|
22 |
21 |
p. 6026-6038
13 p.
|
artikel
|
| 53 |
Synthesis, molecular docking and biological evaluation of coumarin derivatives containing piperazine skeleton as potential antibacterial agents
|
Wang, She-Feng
|
|
2014
|
22 |
21 |
p. 5727-5737
11 p.
|
artikel
|
| 54 |
Synthesis of chiral chloroquine and its analogues as antimalarial agents
|
Sinha, Manish
|
|
2014
|
22 |
21 |
p. 5950-5960
11 p.
|
artikel
|
| 55 |
Synthesis of 3′,4′-difluoro-3′-deoxyribonucleosides and its evaluation of the biological activities: Discovery of a novel type of anti-HCV agent 3′,4′-difluorocordycepin
|
Shimada, Hisashi
|
|
2014
|
22 |
21 |
p. 6174-6182
9 p.
|
artikel
|
| 56 |
Synthesis of IB-01212 by multiple N-methylations of peptide bonds
|
Nabika, Ryota
|
|
2014
|
22 |
21 |
p. 6156-6162
7 p.
|
artikel
|
| 57 |
Synthesis of iboga-like isoquinuclidines: Dual opioid receptors agonists having antinociceptive properties
|
Banerjee, Tuhin Suvro
|
|
2014
|
22 |
21 |
p. 6062-6070
9 p.
|
artikel
|
| 58 |
Thieno[2,3-b]pyridines—A new class of multidrug resistance (MDR) modulators
|
Krauze, Aivars
|
|
2014
|
22 |
21 |
p. 5860-5870
11 p.
|
artikel
|
| 59 |
Thymol and eugenol derivatives as potential antileishmanial agents
|
de Morais, Selene Maia
|
|
2014
|
22 |
21 |
p. 6250-6255
6 p.
|
artikel
|
| 60 |
Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor
|
Inamine, Shogo
|
|
2014
|
22 |
21 |
p. 5902-5909
8 p.
|
artikel
|
| 61 |
Tryptophan-based fluorophores for studying protein conformational changes
|
Talukder, Poulami
|
|
2014
|
22 |
21 |
p. 5924-5934
11 p.
|
artikel
|
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