| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Abbott Physicochemical Tiering (APT)—A unified approach to HTS triage
|
Cox, Philip B.
|
|
2012
|
20 |
14 |
p. 4564-4573
10 p.
|
artikel
|
| 2 |
A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity
|
Wellington, Kevin W.
|
|
2012
|
20 |
14 |
p. 4472-4481
10 p.
|
artikel
|
| 3 |
Aminothienopyridazine inhibitors of tau aggregation: Evaluation of structure–activity relationship leads to selection of candidates with desirable in vivo properties
|
Ballatore, Carlo
|
|
2012
|
20 |
14 |
p. 4451-4461
11 p.
|
artikel
|
| 4 |
Analogs of N′-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases
|
Bhat, Shridhar
|
|
2012
|
20 |
14 |
p. 4507-4513
7 p.
|
artikel
|
| 5 |
Antitumor agents 294. Novel E-ring-modified camptothecin–4β-anilino-4′-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents
|
Ye, Deyong
|
|
2012
|
20 |
14 |
p. 4489-4494
6 p.
|
artikel
|
| 6 |
Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases
|
Mak, Lok Hang
|
|
2012
|
20 |
14 |
p. 4371-4376
6 p.
|
artikel
|
| 7 |
Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding mode
|
Shi, Genbin
|
|
2012
|
20 |
14 |
p. 4303-4309
7 p.
|
artikel
|
| 8 |
Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles
|
Holler, Jes Gitz
|
|
2012
|
20 |
14 |
p. 4514-4521
8 p.
|
artikel
|
| 9 |
Covalent protein–oligonucleotide conjugates by copper-free click reaction
|
Khatwani, Santoshkumar L.
|
|
2012
|
20 |
14 |
p. 4532-4539
8 p.
|
artikel
|
| 10 |
Deconstructing 14-phenylpropyloxymetopon: Minimal requirements for binding to mu opioid receptors
|
Stavitskaya, Lidiya
|
|
2012
|
20 |
14 |
p. 4556-4563
8 p.
|
artikel
|
| 11 |
Design, synthesis and antimicrobial activities of nitroimidazole derivatives containing 1,3,4-oxadiazole scaffold as FabH inhibitors
|
Li, Yao
|
|
2012
|
20 |
14 |
p. 4316-4322
7 p.
|
artikel
|
| 12 |
Design, synthesis and antitumor activities of novel bis-aryl ureas derivatives as Raf kinase inhibitors
|
Zhan, Wenhu
|
|
2012
|
20 |
14 |
p. 4323-4329
7 p.
|
artikel
|
| 13 |
Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT1 receptor antagonists
|
Zhang, Jun
|
|
2012
|
20 |
14 |
p. 4208-4216
9 p.
|
artikel
|
| 14 |
Design, synthesis, biological evaluation and molecular modeling of novel 1,3,4-oxadiazole derivatives based on Vanillic acid as potential immunosuppressive agents
|
Tang, Jian-Feng
|
|
2012
|
20 |
14 |
p. 4226-4236
11 p.
|
artikel
|
| 15 |
Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors
|
Moran, Matthew D.
|
|
2012
|
20 |
14 |
p. 4482-4488
7 p.
|
artikel
|
| 16 |
DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences
|
Viswesh, Velliyur
|
|
2012
|
20 |
14 |
p. 4413-4421
9 p.
|
artikel
|
| 17 |
Edible Myrciaria vexator fruits: Bioactive phenolics for potential COPD therapy
|
Dastmalchi, Keyvan
|
|
2012
|
20 |
14 |
p. 4549-4555
7 p.
|
artikel
|
| 18 |
Editorial board
|
|
|
2012
|
20 |
14 |
p. IFC-
1 p.
|
artikel
|
| 19 |
Effect of C-ring modifications on the cytotoxicity of spirostan saponins and related glycosides
|
Pérez-Labrada, Karell
|
|
2012
|
20 |
14 |
p. 4522-4531
10 p.
|
artikel
|
| 20 |
Functional characterization of recombinant hyoscyamine 6β-hydroxylase from Atropa belladonna
|
Li, Jing
|
|
2012
|
20 |
14 |
p. 4356-4363
8 p.
|
artikel
|
| 21 |
Furin inhibitors: Importance of the positive formal charge and beyond
|
López-Vallejo, Fabian
|
|
2012
|
20 |
14 |
p. 4462-4471
10 p.
|
artikel
|
| 22 |
Graphical contents list
|
|
|
2012
|
20 |
14 |
p. 4173-4185
13 p.
|
artikel
|
| 23 |
Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: Design, synthesis and X-ray crystal structures of enzyme inhibitor complexes
|
Sandgren, Veronica
|
|
2012
|
20 |
14 |
p. 4377-4389
13 p.
|
artikel
|
| 24 |
Hyrtioreticulins A–E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus
|
Yamanokuchi, Rumi
|
|
2012
|
20 |
14 |
p. 4437-4442
6 p.
|
artikel
|
| 25 |
Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives
|
Okaecwe, Thokozile
|
|
2012
|
20 |
14 |
p. 4336-4347
12 p.
|
artikel
|
| 26 |
Modified tetrahalogenated benzimidazoles with CK2 inhibitory activity are active against human prostate cancer cells LNCaP in vitro
|
Schneider, Carolin C.
|
|
2012
|
20 |
14 |
p. 4390-4396
7 p.
|
artikel
|
| 27 |
Myxobacteria versus sponge-derived alkaloids: The bengamide family identified as potent immune modulating agents by scrutiny of LC–MS/ELSD libraries
|
Johnson, Tyler A.
|
|
2012
|
20 |
14 |
p. 4348-4355
8 p.
|
artikel
|
| 28 |
Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold
|
Gomaa, Mohamed S.
|
|
2012
|
20 |
14 |
p. 4201-4207
7 p.
|
artikel
|
| 29 |
Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors
|
Kumar, Satish
|
|
2012
|
20 |
14 |
p. 4237-4244
8 p.
|
artikel
|
| 30 |
Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents
|
Gangjee, Aleem
|
|
2012
|
20 |
14 |
p. 4217-4225
9 p.
|
artikel
|
| 31 |
Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: The hydrophobic side chain influences type A subtype selectivity
|
Li, Yanwu
|
|
2012
|
20 |
14 |
p. 4582-4589
8 p.
|
artikel
|
| 32 |
Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation
|
Kashida, Hiromu
|
|
2012
|
20 |
14 |
p. 4310-4315
6 p.
|
artikel
|
| 33 |
RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines
|
Tashiro, Takuya
|
|
2012
|
20 |
14 |
p. 4540-4548
9 p.
|
artikel
|
| 34 |
Selective hydroboration of dieneamines. Formation of hydroxyalkylphenothiazines as MDR modulators
|
Takács, Daniella
|
|
2012
|
20 |
14 |
p. 4258-4270
13 p.
|
artikel
|
| 35 |
Self-calibrating viscosity probes: Design and subcellular localization
|
Dakanali, Marianna
|
|
2012
|
20 |
14 |
p. 4443-4450
8 p.
|
artikel
|
| 36 |
Structure–activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent
|
Mun, Jiyoung
|
|
2012
|
20 |
14 |
p. 4590-4597
8 p.
|
artikel
|
| 37 |
Structure-based design of rhodanine-based acylsulfonamide derivatives as antagonists of the anti-apoptotic Bcl-2 protein
|
Li, Huan-qiu
|
|
2012
|
20 |
14 |
p. 4194-4200
7 p.
|
artikel
|
| 38 |
Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC–EGFR dual inhibitors
|
Zuo, Miao
|
|
2012
|
20 |
14 |
p. 4405-4412
8 p.
|
artikel
|
| 39 |
Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids
|
Malysheva, Yulia B.
|
|
2012
|
20 |
14 |
p. 4271-4278
8 p.
|
artikel
|
| 40 |
Synthesis and evaluation of a radioiodinated bladder cancer specific peptide
|
Ha, Yeong Su
|
|
2012
|
20 |
14 |
p. 4330-4335
6 p.
|
artikel
|
| 41 |
Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging
|
Herth, Matthias M.
|
|
2012
|
20 |
14 |
p. 4574-4581
8 p.
|
artikel
|
| 42 |
Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups
|
Tu, Zhude
|
|
2012
|
20 |
14 |
p. 4422-4429
8 p.
|
artikel
|
| 43 |
Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α1-adrenoceptor antagonistic properties
|
Handzlik, Jadwiga
|
|
2012
|
20 |
14 |
p. 4245-4257
13 p.
|
artikel
|
| 44 |
Synthesis and structure–activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents
|
Yamazaki, Yuri
|
|
2012
|
20 |
14 |
p. 4279-4289
11 p.
|
artikel
|
| 45 |
Synthesis, biological evaluation and molecular docking studies of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives as inhibitors of HDAC activity
|
Li, Xi
|
|
2012
|
20 |
14 |
p. 4430-4436
7 p.
|
artikel
|
| 46 |
Synthesis of 6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one derivatives as potential anticancer agents
|
Tseng, Chih-Hua
|
|
2012
|
20 |
14 |
p. 4397-4404
8 p.
|
artikel
|
| 47 |
Systematic SAR study of the side chain of nonsecosteroidal vitamin D3 analogs
|
Kashiwagi, Hirotaka
|
|
2012
|
20 |
14 |
p. 4495-4506
12 p.
|
artikel
|
| 48 |
The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer
|
Aviñó, Anna
|
|
2012
|
20 |
14 |
p. 4186-4193
8 p.
|
artikel
|
| 49 |
The influence of hydroquinone on tyrosinase kinetics
|
Stratford, Michael R.L.
|
|
2012
|
20 |
14 |
p. 4364-4370
7 p.
|
artikel
|
| 50 |
Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1)
|
Orchard, Alexandra
|
|
2012
|
20 |
14 |
p. 4290-4302
13 p.
|
artikel
|
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