| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A binary QSAR model for classification of hERG potassium channel blockers
|
Thai, Khac-Minh
|
|
2008
|
16 |
7 |
p. 4107-4119
13 p.
|
artikel
|
| 2 |
A class of novel nitronyl nitroxide labeling basic and acidic amino acids: Synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations
|
Zhang, Jianwei
|
|
2008
|
16 |
7 |
p. 4019-4028
10 p.
|
artikel
|
| 3 |
Alkyl deoxy-arabino-hexopyranosides: Synthesis, surface properties, and biological activities
|
Silva, Filipa V.M.
|
|
2008
|
16 |
7 |
p. 4083-4092
10 p.
|
artikel
|
| 4 |
A novel sesquiterpene lactone from Centaurea pullata: Structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties
|
Djeddi, Samah
|
|
2008
|
16 |
7 |
p. 3725-3731
7 p.
|
artikel
|
| 5 |
Antioxidant and cytotoxic activities of canadine: Biological effects and structural aspects
|
Correché, Estela R.
|
|
2008
|
16 |
7 |
p. 3641-3651
11 p.
|
artikel
|
| 6 |
A single thiourea group is not enough to get stable thiourea lipoplexes
|
Kabha, Eihab
|
|
2008
|
16 |
7 |
p. 4003-4008
6 p.
|
artikel
|
| 7 |
A spectroscopy approach for the study of the interactions of bioactive vanadium species with bovine serum albumin
|
Ferrer, Evelina G.
|
|
2008
|
16 |
7 |
p. 3878-3886
9 p.
|
artikel
|
| 8 |
A structural analysis of the differential cytotoxicity of chemicals in the NCI-60 cancer cell lines
|
Chakravarti, Suman K.
|
|
2008
|
16 |
7 |
p. 4052-4063
12 p.
|
artikel
|
| 9 |
Bioactive alkenylphenols from Piper obliquum
|
Valdivia, Carola
|
|
2008
|
16 |
7 |
p. 4120-4126
7 p.
|
artikel
|
| 10 |
4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators
|
Colabufo, Nicola Antonio
|
|
2008
|
16 |
7 |
p. 3732-3743
12 p.
|
artikel
|
| 11 |
γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity
|
Sako, Kumiko
|
|
2008
|
16 |
7 |
p. 3780-3790
11 p.
|
artikel
|
| 12 |
Carbonic anhydrase activators: Activation of the human tumor-associated isozymes IX and XII with amino acids and amines
|
Pastorekova, Silvia
|
|
2008
|
16 |
7 |
p. 3530-3536
7 p.
|
artikel
|
| 13 |
Carbonic anhydrase inhibitors: Inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides
|
Sączewski, Franciszek
|
|
2008
|
16 |
7 |
p. 3933-3940
8 p.
|
artikel
|
| 14 |
1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Synthesis, biological activity, metabolic stability, and solubility
|
Fritsche, Alexandra
|
|
2008
|
16 |
7 |
p. 3489-3500
12 p.
|
artikel
|
| 15 |
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme
|
Shin, Eui Seok
|
|
2008
|
16 |
7 |
p. 3580-3586
7 p.
|
artikel
|
| 16 |
CoMFA and HQSAR studies on 6,7-dimethoxy-4-pyrrolidylquinazoline derivatives as phosphodiesterase10A inhibitors
|
Kulkarni, Shridhar S.
|
|
2008
|
16 |
7 |
p. 3675-3686
12 p.
|
artikel
|
| 17 |
Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens
|
Gouda, Hiroaki
|
|
2008
|
16 |
7 |
p. 3565-3579
15 p.
|
artikel
|
| 18 |
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity
|
Zhu, Zhengxiang
|
|
2008
|
16 |
7 |
p. 3848-3865
18 p.
|
artikel
|
| 19 |
Cytotoxic activity of proflavine diureas: Synthesis, antitumor, evaluation and DNA binding properties of 1′,1″-(acridin-3,6-diyl)-3′,3″-dialkyldiureas
|
Kožurková, Mária
|
|
2008
|
16 |
7 |
p. 3976-3984
9 p.
|
artikel
|
| 20 |
Design and synthesis of cyclic disulfide-bonded antibacterial peptides on the basis of the α helical domain of Tenecin 1, an insect defensin
|
Ahn, Hye-sun
|
|
2008
|
16 |
7 |
p. 4127-4137
11 p.
|
artikel
|
| 21 |
Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: Introducing a diketoacid functionality into delavirdine
|
Wang, Zhengqiang
|
|
2008
|
16 |
7 |
p. 3587-3595
9 p.
|
artikel
|
| 22 |
Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors
|
Alexiou, Polyxeni
|
|
2008
|
16 |
7 |
p. 3926-3932
7 p.
|
artikel
|
| 23 |
Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity
|
Fortuna, Cosimo Gianluca
|
|
2008
|
16 |
7 |
p. 4150-4159
10 p.
|
artikel
|
| 24 |
Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands
|
Song, Kwang-Seop
|
|
2008
|
16 |
7 |
p. 4035-4051
17 p.
|
artikel
|
| 25 |
Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
|
Reddy, M.V. Ramana
|
|
2008
|
16 |
7 |
p. 3907-3916
10 p.
|
artikel
|
| 26 |
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα
|
Mizuno, Cassia S.
|
|
2008
|
16 |
7 |
p. 3800-3808
9 p.
|
artikel
|
| 27 |
Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors
|
Zhang, Jie
|
|
2008
|
16 |
7 |
p. 3839-3847
9 p.
|
artikel
|
| 28 |
Discovery of potent cholecystokinin-2 receptor antagonists: Elucidation of key pharmacophore elements by X-ray crystallographic and NMR conformational analysis
|
Rosen, Mark D.
|
|
2008
|
16 |
7 |
p. 3917-3925
9 p.
|
artikel
|
| 29 |
DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy·dG
|
Weledji, Yvonne N.
|
|
2008
|
16 |
7 |
p. 4029-4034
6 p.
|
artikel
|
| 30 |
Editorial board
|
|
|
2008
|
16 |
7 |
p. IFC-
1 p.
|
artikel
|
| 31 |
Erratum to “Novel analogs of d-e-MAPP and B13. Part 2: Signature effects on bioactive sphingolipids” [Bioorg. Med. Chem. 16 (2008) 1032–1045]
|
Bielawska, Alicja
|
|
2008
|
16 |
7 |
p. 4187-
1 p.
|
artikel
|
| 32 |
Erratum to “Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents” [Bioorg. Med. Chem. 16 (2008) 1015–1031]
|
Szulc, Zdzislaw M.
|
|
2008
|
16 |
7 |
p. 4186-
1 p.
|
artikel
|
| 33 |
Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cells
|
Locatelli, Claudriana
|
|
2008
|
16 |
7 |
p. 3791-3799
9 p.
|
artikel
|
| 34 |
Graphical contents list
|
|
|
2008
|
16 |
7 |
p. 3463-3481
19 p.
|
artikel
|
| 35 |
2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: Synthesis and structure–activity relationship
|
Vicini, Paola
|
|
2008
|
16 |
7 |
p. 3714-3724
11 p.
|
artikel
|
| 36 |
Instructions to contributors
|
|
|
2008
|
16 |
7 |
p. I-
1 p.
|
artikel
|
| 37 |
In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdin
|
Bulmer, Andrew C.
|
|
2008
|
16 |
7 |
p. 3616-3625
10 p.
|
artikel
|
| 38 |
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase
|
Hatano, Akihiko
|
|
2008
|
16 |
7 |
p. 3866-3870
5 p.
|
artikel
|
| 39 |
Methoxylation of 3′,4′-aromatic side chains improves P-glycoprotein inhibitory and multidrug resistance reversal activities of 7,8-pyranocoumarin against cancer cells
|
Fong, Wang-Fun
|
|
2008
|
16 |
7 |
p. 3694-3703
10 p.
|
artikel
|
| 40 |
Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9
|
Peng, Chi-Chi
|
|
2008
|
16 |
7 |
p. 4064-4074
11 p.
|
artikel
|
| 41 |
N-Aroyl-3,5-bis(benzylidene)-4-piperidones: A novel class of antimycobacterial agents
|
Das, Umashankar
|
|
2008
|
16 |
7 |
p. 3602-3607
6 p.
|
artikel
|
| 42 |
N-1H-Benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists
|
Benod, Cindy
|
|
2008
|
16 |
7 |
p. 3537-3549
13 p.
|
artikel
|
| 43 |
Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A
|
Wang, Si-Hong
|
|
2008
|
16 |
7 |
p. 3596-3601
6 p.
|
artikel
|
| 44 |
Novel cyclohexene derivatives as anti-sepsis agents: Synthetic studies and inhibition of NO and cytokine production
|
Yamada, Masami
|
|
2008
|
16 |
7 |
p. 3941-3958
18 p.
|
artikel
|
| 45 |
Novel 16-membered macrolides modified at C-12 and C-13 positions of midecamycin A1 and miokamycin. Part 1: Synthesis and evaluation of 12,13-carbamate and 12-arylalkylamino-13-hydroxy analogues
|
Miura, Tomoaki
|
|
2008
|
16 |
7 |
p. 3985-4002
18 p.
|
artikel
|
| 46 |
Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity
|
Kamal, Ahmed
|
|
2008
|
16 |
7 |
p. 3895-3906
12 p.
|
artikel
|
| 47 |
Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation
|
Wiemer, Andrew J.
|
|
2008
|
16 |
7 |
p. 3652-3660
9 p.
|
artikel
|
| 48 |
Platinum(II) complexes with steroidal esters of l-methionine and l-histidine: Synthesis, characterization and cytotoxic activity
|
Kvasnica, Miroslav
|
|
2008
|
16 |
7 |
p. 3704-3713
10 p.
|
artikel
|
| 49 |
Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent
|
Purushottamachar, Puranik
|
|
2008
|
16 |
7 |
p. 3519-3529
11 p.
|
artikel
|
| 50 |
Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones
|
Serra, H.
|
|
2008
|
16 |
7 |
p. 4009-4018
10 p.
|
artikel
|
| 51 |
Selective plasma protein binding of antimalarial drugs to α1-acid glycoprotein
|
Zsila, Ferenc
|
|
2008
|
16 |
7 |
p. 3759-3772
14 p.
|
artikel
|
| 52 |
Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane
|
Bissel, Philippe
|
|
2008
|
16 |
7 |
p. 3557-3564
8 p.
|
artikel
|
| 53 |
Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR
|
Michalczyk, Anja
|
|
2008
|
16 |
7 |
p. 3482-3488
7 p.
|
artikel
|
| 54 |
Structure–activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects
|
Takasawa, Ryoko
|
|
2008
|
16 |
7 |
p. 3969-3975
7 p.
|
artikel
|
| 55 |
Structure-based virtual screening against SARS-3CLpro to identify novel non-peptidic hits
|
Mukherjee, Prasenjit
|
|
2008
|
16 |
7 |
p. 4138-4149
12 p.
|
artikel
|
| 56 |
Studies on quinones. Part 43: Synthesis and cytotoxic evaluation of polyoxyethylene-containing 1,4-naphthoquinones
|
Valderrama, Jaime A.
|
|
2008
|
16 |
7 |
p. 3687-3693
7 p.
|
artikel
|
| 57 |
Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines
|
Kok, Stanton Hon Lung
|
|
2008
|
16 |
7 |
p. 3626-3631
6 p.
|
artikel
|
| 58 |
Synthesis and antifungal activity of novel sulfoxide derivatives containing trimethoxyphenyl substituted 1,3,4-thiadiazole and 1,3,4-oxadiazole moiety
|
Liu, Fang
|
|
2008
|
16 |
7 |
p. 3632-3640
9 p.
|
artikel
|
| 59 |
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors
|
Wang, Yue-Ping
|
|
2008
|
16 |
7 |
p. 3887-3894
8 p.
|
artikel
|
| 60 |
Synthesis and DNA-cleaving activity of lactenediynes conjugated with DNA-complexing moieties
|
Banfi, Luca
|
|
2008
|
16 |
7 |
p. 3501-3518
18 p.
|
artikel
|
| 61 |
Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core
|
Bonger, Kimberly M.
|
|
2008
|
16 |
7 |
p. 3744-3758
15 p.
|
artikel
|
| 62 |
Synthesis and GABAA receptor activity of oxygen-bridged neurosteroid analogs
|
Alvarez, Lautaro D.
|
|
2008
|
16 |
7 |
p. 3831-3838
8 p.
|
artikel
|
| 63 |
Synthesis and neuropharmacological evaluation of 2-aryl- and alkylapomorphines
|
Sipos, Attila
|
|
2008
|
16 |
7 |
p. 3773-3779
7 p.
|
artikel
|
| 64 |
Synthesis and structure–activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
|
Fukushima, Hiroshi
|
|
2008
|
16 |
7 |
p. 4093-4106
14 p.
|
artikel
|
| 65 |
Synthesis, antimalarial activity, structure–activity relationship analysis of thieno-[3,2-b]benzothiazine S,S-dioxide analogs
|
Barazarte, Arthur
|
|
2008
|
16 |
7 |
p. 3661-3674
14 p.
|
artikel
|
| 66 |
Synthesis, DNA binding and cleavage activities of the copper (II) complexes of estrogen-macrocyclic polyamine conjugates
|
Yang, Xin-Bin
|
|
2008
|
16 |
7 |
p. 3871-3877
7 p.
|
artikel
|
| 67 |
Synthesis of curcumin mimics with multidrug resistance reversal activities
|
Um, Yumi
|
|
2008
|
16 |
7 |
p. 3608-3615
8 p.
|
artikel
|
| 68 |
Synthesis of eudistomin D analogues and its effects on adenosine receptors
|
Ishiyama, Haruaki
|
|
2008
|
16 |
7 |
p. 3825-3830
6 p.
|
artikel
|
| 69 |
Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-l-homocysteine hydrolase
|
Ando, Takayuki
|
|
2008
|
16 |
7 |
p. 3809-3815
7 p.
|
artikel
|
| 70 |
Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivatives
|
Liu, Xin-Hua
|
|
2008
|
16 |
7 |
p. 4075-4082
8 p.
|
artikel
|
| 71 |
Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator
|
Frezza, Marine
|
|
2008
|
16 |
7 |
p. 3550-3556
7 p.
|
artikel
|
| 72 |
The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds
|
Hasinoff, Brian B.
|
|
2008
|
16 |
7 |
p. 3959-3968
10 p.
|
artikel
|
| 73 |
The synthesis of 5-substituted ring E analogs of methyllycaconitine via the Suzuki–Miyaura cross-coupling reaction
|
Huang, Junfeng
|
|
2008
|
16 |
7 |
p. 3816-3824
9 p.
|
artikel
|
| 74 |
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure–activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate
|
Cesarini, Sara
|
|
2008
|
16 |
7 |
p. 4173-4185
13 p.
|
artikel
|
| 75 |
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure–activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates
|
Cesarini, Sara
|
|
2008
|
16 |
7 |
p. 4160-4172
13 p.
|
artikel
|
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