| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
|
Spencer, John
|
|
2008
|
16 |
6 |
p. 2974-2983
10 p.
|
artikel
|
| 2 |
A comparative density-functional study of the reaction mechanism of the O2-dependent coproporphyrinogen III oxidase
|
Silva, Pedro J.
|
|
2008
|
16 |
6 |
p. 2726-2733
8 p.
|
artikel
|
| 3 |
A genetic algorithm optimized fuzzy neural network analysis of the affinity of inhibitors for HIV-1 protease
|
Fabry-Asztalos, Levente
|
|
2008
|
16 |
6 |
p. 2903-2911
9 p.
|
artikel
|
| 4 |
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor
|
Stefanachi, Angela
|
|
2008
|
16 |
6 |
p. 2852-2869
18 p.
|
artikel
|
| 5 |
A new generation of adenosine receptor antagonists: From di- to trisubstituted aminopyrimidines
|
van Veldhoven, Jacobus P.D.
|
|
2008
|
16 |
6 |
p. 2741-2752
12 p.
|
artikel
|
| 6 |
A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-Propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol
|
Liu, Danyang
|
|
2008
|
16 |
6 |
p. 3438-3444
7 p.
|
artikel
|
| 7 |
Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2-a]quinoline-6-carboxylic acid
|
Dinakaran, Murugesan
|
|
2008
|
16 |
6 |
p. 3408-3418
11 p.
|
artikel
|
| 8 |
Binding to human serum albumin of zidovudine (AZT) and novel AZT derivatives. Experimental and theoretical analyses
|
Quevedo, Mario A.
|
|
2008
|
16 |
6 |
p. 2779-2790
12 p.
|
artikel
|
| 9 |
Biocatalytic and semisynthetic optimization of the anti-invasive tobacco (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol
|
El Sayed, Khalid A.
|
|
2008
|
16 |
6 |
p. 2886-2893
8 p.
|
artikel
|
| 10 |
Conformations of 3-carboxylic esters essential for neurotoxicity in veratrum alkaloids are loosely restricted and fluctuate
|
Niitsu, Ai
|
|
2008
|
16 |
6 |
p. 3025-3031
7 p.
|
artikel
|
| 11 |
Core-modified porphyrins. Part 6: Effects of lipophilicity and core structures on physicochemical and biological properties in vitro
|
Ngen, Ethel J.
|
|
2008
|
16 |
6 |
p. 3171-3183
13 p.
|
artikel
|
| 12 |
Corrigendum to “Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′O)-methyltransferase” [Bioorg. Med. Chem. 15 (2007) 7795–7802]
|
Luzhkov, Victor B.
|
|
2008
|
16 |
6 |
p. 3462-
1 p.
|
artikel
|
| 13 |
Deoxygenated phosphorothioate inositol phosphate analogs: Synthesis, phosphatase stability, and binding affinity
|
Liu, Xiaodan
|
|
2008
|
16 |
6 |
p. 3419-3427
9 p.
|
artikel
|
| 14 |
1-Deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae
|
Naganuma, Mitsuki
|
|
2008
|
16 |
6 |
p. 2939-2944
6 p.
|
artikel
|
| 15 |
Design and synthesis of biologically active analogues of vitamin K2: Evaluation of their biological activities with cultured human cell lines
|
Suhara, Yoshitomo
|
|
2008
|
16 |
6 |
p. 3108-3117
10 p.
|
artikel
|
| 16 |
Design, synthesis and cell growth inhibitory activity of a series of novel aminosubstituted xantheno[1,2-d]imidazoles in breast cancer cells
|
Kostakis, Ioannis K.
|
|
2008
|
16 |
6 |
p. 3445-3455
11 p.
|
artikel
|
| 17 |
Development of polymeric drug delivery system for recognizing vascular endothelial dysfunction
|
Ikuta, Kenjiro
|
|
2008
|
16 |
6 |
p. 2811-2818
8 p.
|
artikel
|
| 18 |
Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: Synthesis, cyclooxygenase inhibition, and nitric oxide release studies
|
Abdellatif, Khaled R.A.
|
|
2008
|
16 |
6 |
p. 3302-3308
7 p.
|
artikel
|
| 19 |
Discovery of piperazinylimidazo[1,2-a]pyridines as novel S4 binding elements for orally active Factor Xa inhibitors
|
Imaeda, Yasuhiro
|
|
2008
|
16 |
6 |
p. 3125-3140
16 p.
|
artikel
|
| 20 |
Disruption of Kv1.1 N-type inactivation by novel small molecule inhibitors (disinactivators)
|
Lu, Qiang
|
|
2008
|
16 |
6 |
p. 3067-3075
9 p.
|
artikel
|
| 21 |
Docking analyses on human muscarinic receptors: Unveiling the subtypes peculiarities in agonists binding
|
Vistoli, Giulio
|
|
2008
|
16 |
6 |
p. 3049-3058
10 p.
|
artikel
|
| 22 |
3D-QSAR CoMFA studies on bis-coumarine analogues as urease inhibitors: A strategic design in anti-urease agents
|
Zaheer-ul-Haq,
|
|
2008
|
16 |
6 |
p. 3456-3461
6 p.
|
artikel
|
| 23 |
Editorial board
|
|
|
2008
|
16 |
6 |
p. IFC-
1 p.
|
artikel
|
| 24 |
Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases
|
Minami, Yasuhiro
|
|
2008
|
16 |
6 |
p. 2734-2740
7 p.
|
artikel
|
| 25 |
Effects of lipid constituents on membrane-permeabilizing activity of amphidinols
|
Morsy, Nagy
|
|
2008
|
16 |
6 |
p. 3084-3090
7 p.
|
artikel
|
| 26 |
Exploring the potential of 3′-O-carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin
|
Ghosh, Kalyan S.
|
|
2008
|
16 |
6 |
p. 2819-2828
10 p.
|
artikel
|
| 27 |
Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: Interaction with dopamine, serotonin, and norepinephrine transporters
|
Mishra, Manoj
|
|
2008
|
16 |
6 |
p. 2769-2778
10 p.
|
artikel
|
| 28 |
Graphical contents list
|
|
|
2008
|
16 |
6 |
p. 2707-2725
19 p.
|
artikel
|
| 29 |
Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety
|
Rönn, Robert
|
|
2008
|
16 |
6 |
p. 2955-2967
13 p.
|
artikel
|
| 30 |
Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts
|
Gediya, Lalji K.
|
|
2008
|
16 |
6 |
p. 3352-3360
9 p.
|
artikel
|
| 31 |
Inhibition of 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) by aldose reductase inhibitors
|
Dhagat, Urmi
|
|
2008
|
16 |
6 |
p. 3245-3254
10 p.
|
artikel
|
| 32 |
Inhibitory property of the Piper betel phenolics against photosensitization-induced biological damages
|
Mula, Soumyaditya
|
|
2008
|
16 |
6 |
p. 2932-2938
7 p.
|
artikel
|
| 33 |
Instructions to contributors
|
|
|
2008
|
16 |
6 |
p. I-
1 p.
|
artikel
|
| 34 |
Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells
|
Akao, Yukihiro
|
|
2008
|
16 |
6 |
p. 2803-2810
8 p.
|
artikel
|
| 35 |
Lead identification of acetylcholinesterase inhibitors–histamine H3 receptor antagonists from molecular modeling
|
Bembenek, Scott D.
|
|
2008
|
16 |
6 |
p. 2968-2973
6 p.
|
artikel
|
| 36 |
Molecular modeling studies of N-substituted pyrrole derivatives—Potential HIV-1 gp41 inhibitors
|
Teixeira, Cátia
|
|
2008
|
16 |
6 |
p. 3039-3048
10 p.
|
artikel
|
| 37 |
New anti-viral drugs for the treatment of the common cold
|
Maugeri, Caterina
|
|
2008
|
16 |
6 |
p. 3091-3107
17 p.
|
artikel
|
| 38 |
New triterpenoid saponins with strong α-glucosidase inhibitory activity from the roots of Gypsophila oldhamiana
|
Luo, Jian-Guang
|
|
2008
|
16 |
6 |
p. 2912-2920
9 p.
|
artikel
|
| 39 |
Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors
|
Ma, Zhongze
|
|
2008
|
16 |
6 |
p. 3218-3223
6 p.
|
artikel
|
| 40 |
Novel nitroheterocyclic hypoxic markers for solid tumor: Synthesis and biological evaluation
|
Zhu, Weiping
|
|
2008
|
16 |
6 |
p. 3255-3260
6 p.
|
artikel
|
| 41 |
Novel 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine as trypanocidal agents: Chemical and biological studies
|
da Silva Ferreira, Welisson
|
|
2008
|
16 |
6 |
p. 2984-2991
8 p.
|
artikel
|
| 42 |
N-Phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents
|
Matesic, Lidia
|
|
2008
|
16 |
6 |
p. 3118-3124
7 p.
|
artikel
|
| 43 |
Oligo(tyrosine sulfate)s as heparin pentasaccharide mimic: Evaluation by surface noncovalent affinity mass spectrometry
|
Yamaguchi, Miyuki
|
|
2008
|
16 |
6 |
p. 3342-3351
10 p.
|
artikel
|
| 44 |
11-(Pyridinylphenyl)steroids—A new class of mixed-profile progesterone agonists/antagonists
|
Rewinkel, Jos
|
|
2008
|
16 |
6 |
p. 2753-2763
11 p.
|
artikel
|
| 45 |
Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation
|
Wright, Christine M.
|
|
2008
|
16 |
6 |
p. 3291-3301
11 p.
|
artikel
|
| 46 |
QSAR modeling of the rodent carcinogenicity of nitrocompounds
|
Helguera, Aliuska Morales
|
|
2008
|
16 |
6 |
p. 3395-3407
13 p.
|
artikel
|
| 47 |
Recognition of T·A interruption by 2′,4′-BNAs bearing heteroaromatic nucleobases through parallel motif triplex formation
|
Obika, Satoshi
|
|
2008
|
16 |
6 |
p. 2945-2954
10 p.
|
artikel
|
| 48 |
Role of benzimidazole (Bid) in the δ-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502)
|
Salvadori, Severo
|
|
2008
|
16 |
6 |
p. 3032-3038
7 p.
|
artikel
|
| 49 |
Structure–activity relationship analysis of N-benzoylpyrazoles for elastase inhibitory activity: A simplified approach using atom pair descriptors
|
Khlebnikov, Andrei I.
|
|
2008
|
16 |
6 |
p. 2791-2802
12 p.
|
artikel
|
| 50 |
Structure–activity relationship of uniconazole, a potent inhibitor of ABA 8′-hydroxylase, with a focus on hydrophilic functional groups and conformation
|
Todoroki, Yasushi
|
|
2008
|
16 |
6 |
p. 3141-3152
12 p.
|
artikel
|
| 51 |
Structure–activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties
|
Palin, Ronald
|
|
2008
|
16 |
6 |
p. 2829-2851
23 p.
|
artikel
|
| 52 |
Structure and estrogenic activity of new lignans from Iryanthera lancifolia
|
Mesa-Siverio, Dulce
|
|
2008
|
16 |
6 |
p. 3387-3394
8 p.
|
artikel
|
| 53 |
Structure–reactivity relationships for electrophilic sugars in interaction with nucleophilic biological targets
|
Campodónico, Paola R.
|
|
2008
|
16 |
6 |
p. 3184-3190
7 p.
|
artikel
|
| 54 |
Synthesis, analgesic, anti-inflammatory, and antimicrobial activity of some novel pyrimido[4,5-b]quinolin-4-ones
|
El-Gazzar, Abdel-Rahman B.A.
|
|
2008
|
16 |
6 |
p. 3261-3273
13 p.
|
artikel
|
| 55 |
Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives
|
Tseng, Chih-Hua
|
|
2008
|
16 |
6 |
p. 3153-3162
10 p.
|
artikel
|
| 56 |
Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration
|
Chen, Zhuo
|
|
2008
|
16 |
6 |
p. 3076-3083
8 p.
|
artikel
|
| 57 |
Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase
|
Szajnman, Sergio H.
|
|
2008
|
16 |
6 |
p. 3283-3290
8 p.
|
artikel
|
| 58 |
Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain
|
Farina, Carlo
|
|
2008
|
16 |
6 |
p. 3224-3232
9 p.
|
artikel
|
| 59 |
Synthesis and cytotoxic activity of diosgenyl saponin analogues
|
Kaskiw, Matthew J.
|
|
2008
|
16 |
6 |
p. 3209-3217
9 p.
|
artikel
|
| 60 |
Synthesis and exploration of novel curcumin analogues as anti-malarial agents
|
Mishra, Satyendra
|
|
2008
|
16 |
6 |
p. 2894-2902
9 p.
|
artikel
|
| 61 |
Synthesis and in silico biological activity evaluation of new N-substituted pyrazolo-oxazin-2-one systems
|
Benaamane, Nora
|
|
2008
|
16 |
6 |
p. 3059-3066
8 p.
|
artikel
|
| 62 |
Synthesis and in vitro properties of trimethylamine- and phosphonate-substituted carboranylporphyrins for application in BNCT
|
Easson, Michael W.
|
|
2008
|
16 |
6 |
p. 3191-3208
18 p.
|
artikel
|
| 63 |
Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety
|
Jung, Bettina
|
|
2008
|
16 |
6 |
p. 2870-2885
16 p.
|
artikel
|
| 64 |
Synthesis and structure–activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists
|
Shimada, Itsuro
|
|
2008
|
16 |
6 |
p. 3309-3320
12 p.
|
artikel
|
| 65 |
Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists
|
Shen, Lan
|
|
2008
|
16 |
6 |
p. 3321-3341
21 p.
|
artikel
|
| 66 |
Synthesis and structure–activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem
|
Cappelli, Andrea
|
|
2008
|
16 |
6 |
p. 3428-3437
10 p.
|
artikel
|
| 67 |
Synthesis and structure–affinity relationships of novel spirocyclic σ receptor ligands with furopyrazole structure
|
Schläger, Torsten
|
|
2008
|
16 |
6 |
p. 2992-3001
10 p.
|
artikel
|
| 68 |
Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans
|
Andujar, Sebastian A.
|
|
2008
|
16 |
6 |
p. 3233-3244
12 p.
|
artikel
|
| 69 |
Synthesis of β- and γ-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates
|
Haemers, Timothy
|
|
2008
|
16 |
6 |
p. 3361-3371
11 p.
|
artikel
|
| 70 |
Synthesis of chemically functionalized superparamagnetic nanoparticles as delivery vectors for chemotherapeutic drugs
|
Hanessian, Stephen
|
|
2008
|
16 |
6 |
p. 2921-2931
11 p.
|
artikel
|
| 71 |
Synthesis of insecticidal fluorinated anthranilic diamides
|
Clark, David A.
|
|
2008
|
16 |
6 |
p. 3163-3170
8 p.
|
artikel
|
| 72 |
Synthesis of naphtho[2,3-a]phenoxazinium chlorides: Structure–activity relationships of these heterocycles and benzo[a]phenoxazinium chlorides as new antimicrobials
|
Frade, Vânia H.J.
|
|
2008
|
16 |
6 |
p. 3274-3282
9 p.
|
artikel
|
| 73 |
Synthetic derivatives of the α- and β-amyrin triterpenes and their antinociceptive properties
|
Soldi, Cristian
|
|
2008
|
16 |
6 |
p. 3377-3386
10 p.
|
artikel
|
| 74 |
Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer
|
Kumar, Srinivas K.
|
|
2008
|
16 |
6 |
p. 2764-2768
5 p.
|
artikel
|
| 75 |
The 2α-(3-hydroxypropyl) group as an active motif in vitamin D3 analogues as agonists of the mutant vitamin D receptor (Arg274Leu)
|
Honzawa, Shinobu
|
|
2008
|
16 |
6 |
p. 3002-3024
23 p.
|
artikel
|
| 76 |
Thiahomoisocitrate: A highly potent inhibitor of homoisocitrate dehydrogenase involved in the α-aminoadipate pathway
|
Yamamoto, Takashi
|
|
2008
|
16 |
6 |
p. 3372-3376
5 p.
|
artikel
|
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