| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A combination of inhibiting microglia activity and remodeling gut microenvironment suppresses the development and progression of experimental autoimmune uveitis
|
Zhou, Jianhong
|
|
|
180 |
C |
p.
|
artikel
|
| 2 |
Aconitase 2 sensitizes MCF-7 cells to cisplatin eliciting p53-mediated apoptosis in a ROS-dependent manner
|
Ciccarone, Fabio
|
|
|
180 |
C |
p.
|
artikel
|
| 3 |
Activation of AMP-activated protein kinase attenuates ethanol-induced ER/oxidative stress and lipid phenotype in human pancreatic acinar cells
|
Srinivasan, Mukund P.
|
|
|
180 |
C |
p.
|
artikel
|
| 4 |
Activation of AMPK/aPKCζ/CREB pathway by metformin is associated with upregulation of GDNF and dopamine
|
Katila, Nikita
|
|
|
180 |
C |
p.
|
artikel
|
| 5 |
Alkannin induces cytotoxic autophagy and apoptosis by promoting ROS-mediated mitochondrial dysfunction and activation of JNK pathway
|
Zheng, Qianwen
|
|
|
180 |
C |
p.
|
artikel
|
| 6 |
Angiotensin-(1–9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism
|
Norambuena-Soto, Ignacio
|
|
|
180 |
C |
p.
|
artikel
|
| 7 |
Approaching coronavirus disease 2019: Mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2
|
Lisi, Lucia
|
|
|
180 |
C |
p.
|
artikel
|
| 8 |
Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer’s and Parkinson’s disease therapeutics
|
Salameh, Therese S.
|
|
|
180 |
C |
p.
|
artikel
|
| 9 |
Caveolin-1 protects against DSS-induced colitis through inhibiting intestinal nitrosative stress and mucosal barrier damage in mice
|
Song, Yuhong
|
|
|
180 |
C |
p.
|
artikel
|
| 10 |
Characterization of the mechanism of action of RDR01752, a novel corrector of F508del-CFTR
|
Lopes-Pacheco, Miquéias
|
|
|
180 |
C |
p.
|
artikel
|
| 11 |
Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-β/Smad signaling pathway
|
Dou, Fang
|
|
|
180 |
C |
p.
|
artikel
|
| 12 |
Corrigendum to “‘Heme oxygenase-1 induction by methylene blue protects RAW264.7 cells from hydrogen peroxide-induced injury” [Biochem Pharmacol 148 (2018) 265–277]
|
Zhang, Xiao-tong
|
|
|
180 |
C |
p.
|
artikel
|
| 13 |
COVID-19: An overview of the current pharmacological interventions, vaccines, and clinical trials
|
Chakraborty, Rohan
|
|
|
180 |
C |
p.
|
artikel
|
| 14 |
Dehydrodieugenol improved lung inflammation in an asthma model by inhibiting the STAT3/SOCS3 and MAPK pathways
|
Santana, Fernanda P.R.
|
|
|
180 |
C |
p.
|
artikel
|
| 15 |
Design and pharmacological profile of a novel covalent partial agonist for the adenosine A1 receptor
|
Yang, Xue
|
|
|
180 |
C |
p.
|
artikel
|
| 16 |
Editorial Board
|
|
|
|
180 |
C |
p.
|
artikel
|
| 17 |
β-estradiol adjusts intestinal function via ERβ and GPR30 mediated PI3K/AKT signaling activation to alleviate postmenopausal dyslipidemia
|
Meng, Qinghai
|
|
|
180 |
C |
p.
|
artikel
|
| 18 |
Etifoxine reverses weight gain and alters the colonic bacterial community in a mouse model of obesity
|
Ibrahim, Khalid S.
|
|
|
180 |
C |
p.
|
artikel
|
| 19 |
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
|
Darbalaei, Sanaz
|
|
|
180 |
C |
p.
|
artikel
|
| 20 |
Evolution of a concept: From accessory protein to key virulence factor, the case of HIV-1 Vpr
|
Wallet, Clémentine
|
|
|
180 |
C |
p.
|
artikel
|
| 21 |
Expression of functional sulfotransferases (SULT) 1A1, 1A3, 1B1, 1C2, 1E1, and 2A1 in common marmosets
|
Uno, Yasuhiro
|
|
|
180 |
C |
p.
|
artikel
|
| 22 |
From fatty hepatocytes to impaired bile flow: Matching model systems for liver biology and disease
|
Kunst, Roni F.
|
|
|
180 |
C |
p.
|
artikel
|
| 23 |
Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice
|
Mamiya, Takayoshi
|
|
|
180 |
C |
p.
|
artikel
|
| 24 |
Globular adiponectin antagonizes leptin-induced growth of cancer cells by modulating inflammasomes activation: Critical role of HO-1 signaling
|
Raut, Pawan Kumar
|
|
|
180 |
C |
p.
|
artikel
|
| 25 |
GR-C/EBPα-IGF1 axis mediated azithromycin-induced liver developmental toxicity in fetal mice
|
Liu, Kexin
|
|
|
180 |
C |
p.
|
artikel
|
| 26 |
Histamine H4 receptor agonists induce epithelial-mesenchymal transition events and enhance mammosphere formation via Src and TGF-β signaling in breast cancer cells
|
Galarza, Tamara E.
|
|
|
180 |
C |
p.
|
artikel
|
| 27 |
Histone deacetylases inhibitors as new potential drugs against Leishmania braziliensis, the main causative agent of new world tegumentary leishmaniasis
|
Ângelo de Souza, Luciana
|
|
|
180 |
C |
p.
|
artikel
|
| 28 |
Human red blood cell uptake and sequestration of arsenite and selenite: Evidence of seleno-bis(S-glutathionyl) arsinium ion formation in human cells
|
Kaur, Gurnit
|
|
|
180 |
C |
p.
|
artikel
|
| 29 |
Identification of N-acyl amino acids that are positive allosteric modulators of glycine receptors
|
Gallagher, Casey I.
|
|
|
180 |
C |
p.
|
artikel
|
| 30 |
Inhibition of RUNX1 promotes cisplatin-induced apoptosis in ovarian cancer cells
|
Xiao, Li
|
|
|
180 |
C |
p.
|
artikel
|
| 31 |
Inhibition of type 4 cAMP-phosphodiesterases (PDE4s) in mice induces hypothermia via effects on behavioral and central autonomous thermoregulation
|
McDonough, Will
|
|
|
180 |
C |
p.
|
artikel
|
| 32 |
Ionizing radiation induces BH4 deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis
|
Yan, Tao
|
|
|
180 |
C |
p.
|
artikel
|
| 33 |
α-Linolenic acid inhibits the migration of human triple-negative breast cancer cells by attenuating Twist1 expression and suppressing Twist1-mediated epithelial-mesenchymal transition
|
Wang, Shih-Chung
|
|
|
180 |
C |
p.
|
artikel
|
| 34 |
Macrophages confer resistance to BET inhibition in triple-negative breast cancer by upregulating IKBKE
|
Qiao, Jianghua
|
|
|
180 |
C |
p.
|
artikel
|
| 35 |
Metabolomic insights into the mode of action of natural products in the treatment of liver disease
|
Beyoğlu, Diren
|
|
|
180 |
C |
p.
|
artikel
|
| 36 |
MiR-23a-5p exacerbates intestinal ischemia–reperfusion injury by promoting oxidative stress via targeting PPAR alpha
|
Li, L.X.
|
|
|
180 |
C |
p.
|
artikel
|
| 37 |
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysis
|
Yang, Cheng-Wei
|
|
|
180 |
C |
p.
|
artikel
|
| 38 |
Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective
|
Bindu, Samik
|
|
|
180 |
C |
p.
|
artikel
|
| 39 |
Oridonin is an antidepressant molecule working through the PPAR-γ/AMPA receptor signaling pathway
|
Liu, Ping
|
|
|
180 |
C |
p.
|
artikel
|
| 40 |
Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines
|
Wu, Chung-Pu
|
|
|
180 |
C |
p.
|
artikel
|
| 41 |
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis
|
Chen, Lei
|
|
|
180 |
C |
p.
|
artikel
|
| 42 |
Pharmacokinetics of gemcitabine and its amino acid ester prodrug following intravenous and oral administrations in mice
|
Thompson, Brian R.
|
|
|
180 |
C |
p.
|
artikel
|
| 43 |
Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function
|
Li, Xaria X.
|
|
|
180 |
C |
p.
|
artikel
|
| 44 |
Potential roles of PP2A-Rac1 signaling axis in pancreatic β-cell dysfunction under metabolic stress: Progress and promise
|
Kowluru, Anjaneyulu
|
|
|
180 |
C |
p.
|
artikel
|
| 45 |
Protective effects of morin against depressive-like behavior prompted by chronic unpredictable mild stress in rats: Possible role of inflammasome-related pathways
|
Hassan, Mennat-Allah M.
|
|
|
180 |
C |
p.
|
artikel
|
| 46 |
P2X7 receptor antagonism preserves retinal ganglion cells in glaucomatous mice
|
Romano, Giovanni Luca
|
|
|
180 |
C |
p.
|
artikel
|
| 47 |
PXR phosphorylated at Ser350 transduces a glucose signal to repress the estrogen sulfotransferase gene in human liver cells and fasting signal in mouse livers
|
Hu, Hao
|
|
|
180 |
C |
p.
|
artikel
|
| 48 |
Resolvin E1 protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress, autophagy and apoptosis by targeting AKT/mTOR signaling
|
Zhang, Jishou
|
|
|
180 |
C |
p.
|
artikel
|
| 49 |
RGFP966, a histone deacetylase 3 inhibitor, promotes glioma stem cell differentiation by blocking TGF-β signaling via SMAD7
|
Liang, Hang
|
|
|
180 |
C |
p.
|
artikel
|
| 50 |
Roles of Lys191 and Lys179 in regulating thermodynamic binding forces of ligands to determine their binding affinity for human histamine H1 receptors
|
Kobayashi, Chihiro
|
|
|
180 |
C |
p.
|
artikel
|
| 51 |
Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy
|
Liu, Xue-qi
|
|
|
180 |
C |
p.
|
artikel
|
| 52 |
20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway
|
Wang, Manying
|
|
|
180 |
C |
p.
|
artikel
|
| 53 |
SMAD-oncoprotein interplay: Potential determining factors in targeted therapies
|
Li, Xinran
|
|
|
180 |
C |
p.
|
artikel
|
| 54 |
TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression
|
Huang, Yapei
|
|
|
180 |
C |
p.
|
artikel
|
| 55 |
The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells
|
Cosialls, Ana M.
|
|
|
180 |
C |
p.
|
artikel
|
| 56 |
The development of a targeted and more potent, anti-Inflammatory derivative of colchicine: Implications for gout
|
Paré, Guillaume
|
|
|
180 |
C |
p.
|
artikel
|
| 57 |
The diverse role of optineurin in pathogenesis of disease
|
Guo, Qingyi
|
|
|
180 |
C |
p.
|
artikel
|
| 58 |
The indirubin derivative 6-bromoindirubin-3′-glycerol-oxime ether (6BIGOE) potently modulates inflammatory cytokine and prostaglandin release from human monocytes through GSK-3 interference
|
Czapka, Anna
|
|
|
180 |
C |
p.
|
artikel
|
| 59 |
The mechanisms of action of chromatin remodelers and implications in development and disease
|
Sahu, Rakesh Kumar
|
|
|
180 |
C |
p.
|
artikel
|
| 60 |
The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to Gαq for signaling but distinctly modulates function of the Gαi-coupled FPR2 and FFAR2
|
Holdfeldt, André
|
|
|
180 |
C |
p.
|
artikel
|
| 61 |
TNF-α inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure
|
Mattos, B.R.
|
|
|
180 |
C |
p.
|
artikel
|
| 62 |
Type 2 diabetes mellitus decreases systemic exposure of clopidogrel active metabolite through upregulation of P-glycoprotein in rats
|
Yao, Hongwei
|
|
|
180 |
C |
p.
|
artikel
|
| 63 |
Vitamin K3 chloro derivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis, and inhibits aggresome formation in hepatocellular carcinoma cells
|
Dawood, Mona
|
|
|
180 |
C |
p.
|
artikel
|
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