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Details van artikel 10 van 17 gevonden artikelen
| Titel: |
Role of the hepatic endocytic compartment in signal transduction |
| Auteur: |
Albert Pol Maria Calvo Mònica Pons Sandra Peiró Noemí Andrés Francesc Tebar Carlos Enrich |
| Verschenen in: |
Electronic journal of pathology and histopathology |
| Paginering: | Jaargang 6 (2002) nr. 1 pagina's 11 |
| Jaar: |
2002-03-25 |
| Inhoud: |
Hormones and growth factors regulate cell metabolism, growth, differentiation and mitogenesis by interacting with plasma membrane located receptors. Upon ligand binding receptors are rapidly internalised into a series of complex membranes system collectively called endocytic compartment. Detailed studies on a number of receptor tyrosine kinases suggest that internalisation, rather than simply serving as a mechanism for uptake, may also allow for selected and regulated signal transduction from intracellular compartments. Although signal transduction is often credited with being a cascade of interactions initiated at the plasma membrane but exerting its final effects in the nucleus, now it has become clear that certain signal-transduction pathways affect membrane trafficking. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 10 van 17 gevonden artikelen
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