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| Titel: |
Efficient Shape Descriptors for Feature Extraction in 3D Protein Structures |
| Auteur: |
Ranganath, Aruna Shet, K. Chandra Shekar Vidyavathi, Nagardone |
| Verschenen in: |
In silico biology |
| Paginering: | Jaargang 7 (2007) nr. 2 pagina's 169-174 |
| Jaar: |
2007-08-14 |
| Inhoud: |
Structural Genomics initiatives are generating an increasing number of protein structures with very limited biochemical characterization. Characterization of a protein's function and understanding the specific nature of a protein's binding is a critical part of both protein engineering and structure-based drug discovery. The accurate detection of binding site in these protein structures can be valuable in determining its function. As shape plays a crucial role in bimolecular recognition and function, the development of shape analysis techniques is important for understanding protein structure-function relationships. This paper describes the use of the continuous wavelet transforms (CWT) for characterizing shape features of 3D protein structures. The goal is to explore the CWT as a multiscale tool to generate rotation- and translation-invariant shape features. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 5 van 12 gevonden artikelen
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