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                                       Details van artikel 2 van 14 gevonden artikelen
 
 
  Analysis of Tandem Repeats Found in 44 Prokaryotic Genomes
 
 
Titel: Analysis of Tandem Repeats Found in 44 Prokaryotic Genomes
Auteur: Mizuta, Satoshi
Munakata, Hikaru
Aimaiti, Abulimiti
Oya, Ichitaro
Oosawa, Kenji
Shimizu, Toshio
Verschenen in: In silico biology
Paginering: Jaargang 6 (2006) nr. 1-2 pagina's 147-159
Jaar: 2006-07-05
Inhoud: Genomes contain various types of repetitive sequences. They may be used as probes for seeking genome rearrangements because they are rather free from the natural selection if they are located in the intergenic regions. In this study, we searched for tandem repeats (TRs) in 44 prokaryotic genomes by the color-coding method and sought the signs of genome rearrangements by detailed analysis of the detected TRs. We found 13,542 tandem repeats from 44 prokaryotic genomes in total ranging from several tens to one thousand per genome. The results of statistical analysis show that TRs tend to exist on high base composition bias regions in some genomes. Moreover, we recognized the characteristic distribution patterns of equivalent TR-pairs in 12 genomes, which are expected to indicate the occurrence of whole-genome duplication (WGD) on the genomes. It is demonstrated that TRs could indeed be used for seeking genome rearrangements. Although it has not been made clear at this time whether or not WGD had occurred in prokaryotic genomes, the results of the analyses of equivalent TR-pairs in this study are thought to be evidences of WGD in these genomes.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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